LOCUS       NM_001080444            2275 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens immunoglobulin superfamily member 5 (IGSF5), mRNA.
ACCESSION   NM_001080444 XM_086761
VERSION     NM_001080444.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2275)
  AUTHORS   Hirabayashi,S., Tajima,M., Yao,I., Nishimura,W., Mori,H. and
            Hata,Y.
  TITLE     JAM4, a junctional cell adhesion molecule interacting with a tight
            junction protein, MAGI-1
  JOURNAL   Mol Cell Biol 23 (12), 4267-4282 (2003)
   PUBMED   12773569
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AF121782.1.
            
            On Feb 11, 2021 this sequence version replaced NM_001080444.1.
            
            Sequence Note:.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK092516.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000380588.5/ ENSP00000369962.4
            RefSeq Select criteria :: based on manual assertion
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-344               AF121782.1         23923-24266
            345-427             AF121782.1         24956-25038
            428-745             AF121782.1         44275-44592
            746-1045            AF121782.1         49656-49955
            1046-1261           AF121782.1         57830-58045
            1262-1283           AF121782.1         66907-66928
            1284-1375           AF121782.1         70748-70839
            1376-1455           AF121782.1         72274-72353
            1456-2275           AF121782.1         80002-80821
FEATURES             Location/Qualifiers
     source          1..2275
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
                     /map="21q22.2"
     gene            1..2275
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /note="immunoglobulin superfamily member 5"
                     /db_xref="GeneID:150084"
                     /db_xref="HGNC:HGNC:5952"
                     /db_xref="MIM:610638"
     exon            1..344
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     CDS             328..1551
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /note="immunoglobulin superfamily 5 like; junctional
                     adhesion molecule 4"
                     /codon_start=1
                     /product="immunoglobulin superfamily member 5"
                     /protein_id="NP_001073913.1"
                     /db_xref="CCDS:CCDS33562.1"
                     /db_xref="GeneID:150084"
                     /db_xref="HGNC:HGNC:5952"
                     /db_xref="MIM:610638"
                     /translation="MGQKERSTADTLPDLEEWKSAAGLRWWQTAVVDGSGSGNEVIEG
                     PQNARVLKGSQARFNCTVSQGWKLIMWALSDMVVLSVRPMEPIITNDRFTSQRYDQGG
                     NFTSEMIIHNVEPSDSGNIRCSLQNSRLHGSAYLTVQVMGELFIPSVNLVVAENEPCE
                     VTCLPSHWTRLPDISWELGLLVSHSSYYFVPEPSDLQSAVSILALTPQSNGTLTCVAT
                     WKSLKARKSATVNLTVIRCPQDTGGGINIPGVLSSLPSLGFSLPTWGKVGLGLAGTML
                     LTPTCTLTIRCCCCRRRCCGCNCCCRCCFCCRRKRGFRIQFQKKSEKEKTNKETETES
                     GNENSGYNSDEQKTTDTASLPPKSCESSDPEQRNSSCGPPHQRADQRPPRPASHPQAS
                     FNLASPEKVSNTTVV"
     exon            345..427
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            428..745
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            746..1045
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1261
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            1262..1283
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1375
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..1455
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..2275
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2255..2260
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /note="hexamer: AATAAA"
     polyA_site      2275
                     /gene="IGSF5"
                     /gene_synonym="GSF5; JAM4"
                     /note="major polyA site"
ORIGIN      
        1 ctctctccgt gtctctctct tagccattac aaacttgggg ccctggcaag ggtggtgggg
       61 aatgggtcct gcataactgc tcatgtcaag agctgtatac ctaaattagg agggacgcca
      121 gggataagac tccctgggct atagcctagg tgcctgagga cgcagcgtag ggcttcctta
      181 gatccctttg gagatacaac ctgctagagg aaatgaaagt ctgaaccatt agtacctagg
      241 aggcagggat cagaggaagt agattcagag gtaaggagaa ttttggggct atactttcaa
      301 gaaagtcgtg ttcgggaccc aggaggtatg ggtcagaagg aaaggagcac agcagatact
      361 ctgccggatc tggaggaatg gaagtcagcg gcgggtctgc gatggtggca aacagcagtg
      421 gtggacggtt ctgggtctgg taatgaagtc atagaaggcc cccaaaatgc aagagtcctg
      481 aagggctccc aggctcgctt caactgcacc gtctcccagg gctggaagct catcatgtgg
      541 gctctcagtg acatggtggt gctaagcgtc aggcccatgg agcccatcat caccaatgac
      601 cgcttcacct ctcagaggta cgaccagggc gggaacttca cctcggagat gatcatccac
      661 aatgtggagc ccagtgattc ggggaacatc agatgcagcc tccagaacag tcgcctgcat
      721 ggatctgctt accttaccgt ccaagttatg ggagagctgt tcattcccag tgttaatctt
      781 gtagtcgctg agaatgaacc ttgtgaagtt acttgtctac cctcacactg gacccggctc
      841 ccggatattt cctgggagct cggtctcctg gtcagccatt caagctatta ttttgttccg
      901 gagcccagcg accttcaaag tgcagtgagc atcctggctc tgaccccaca gagcaatggg
      961 actttgactt gcgtggctac ctggaagagc ctgaaggccc gcaagtctgc aactgtaaat
     1021 ctcactgtga ttcggtgtcc ccaagacact ggaggtggta ttaatattcc aggtgtatta
     1081 tcaagtttac cgagtttagg tttttcattg cctacttggg gcaaagttgg acttggacta
     1141 gcaggcacca tgcttctgac gccgacgtgt actcttacaa tacgctgctg ctgctgccgc
     1201 cgtcgttgtt gtggctgcaa ctgctgctgc cgttgttgtt tctgctgtag aagaaaaaga
     1261 ggatttcgta ttcaatttca aaagaaatct gaaaaagaga agacaaacaa agaaactgag
     1321 acagaaagtg gaaatgaaaa ctccggctac aattcagatg aacaaaagac cacagacacc
     1381 gcttctctcc ctcccaaatc ctgtgaatcc agtgatcctg aacaaagaaa cagtagctgt
     1441 ggccctcctc accagcgggc tgatcaacgt ccacccaggc cagcaagtca tccacaggct
     1501 tcttttaatc tggccagtcc tgagaaggtc agtaatacaa ctgtagtata gcaaagcctt
     1561 ccccaagctc cactgagcac ttggctgaca attcaaaaca cggcgatggc atccttcctt
     1621 tccatcctaa gactggcctg cagctttgcc aacattacct gaagaggaga tgtcggagtc
     1681 atcagaactg atacttgaca gtgagagaag gaatcgattt tcccagagtt caaagtagaa
     1741 tgtgactttt aagaggtttc atggtttttg tgaattccat gaagttacta agtaaaagct
     1801 gcaaattcat cataattttt ctcaacattc aacactccta cttgttaatc caacaaatgg
     1861 tagataaaag tctgtattct accatgcctt tcaaaagttt ttattatctg aaagcatatg
     1921 aagatgatat ttatgtatat ttaatatgta ggggtattat tacatattat cagtgaaata
     1981 cgagtataaa aattagggtc aaccagaaat ctgcaattga ctgtcaaaac tgagctcagt
     2041 taaagtaaga ttcaattcta acatggatgt gcacgttcct aaatatctta tgattgaata
     2101 tttacatgaa ggcattcatt tttatctgcc cctttatcag acctatttgc atctcctcaa
     2161 atgaattaga tgtggcctat gctttgcaga ggatggacct cacctactcc gcacaccgtg
     2221 aaaaaactgg aaatgggcat tgtagtcttt aattaataaa aacaccaaaa atgtg
//
