LOCUS       NM_000876              14061 bp    mRNA    linear   PRI 09-JUL-2024
DEFINITION  Homo sapiens insulin like growth factor 2 receptor (IGF2R), mRNA.
ACCESSION   NM_000876
VERSION     NM_000876.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14061)
  AUTHORS   Li,W., She,L., Zhang,M., Yang,M., Zheng,W., He,H., Wang,P., Dai,Q.
            and Gong,Z.
  TITLE     The associations of IGF2, IGF2R and IGF2BP2 gene polymorphisms with
            gestational diabetes mellitus: A case-control study
  JOURNAL   PLoS One 19 (5), e0298063 (2024)
   PUBMED   38701040
  REMARK    GeneRIF: The associations of IGF2, IGF2R and IGF2BP2 gene
            polymorphisms with gestational diabetes mellitus: A case-control
            study.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14061)
  AUTHORS   Pileggi,S., Colombo,E.A., Ancona,S., Quadri,R., Bernardelli,C.,
            Colapietro,P., Taiana,M., Fontana,L., Miozzo,M., Lesma,E. and
            Sirchia,S.M.
  TITLE     Dysfunction in IGF2R Pathway and Associated Perturbations in
            Autophagy and WNT Processes in Beckwith-Wiedemann Syndrome Cell
            Lines
  JOURNAL   Int J Mol Sci 25 (7), 3586 (2024)
   PUBMED   38612397
  REMARK    GeneRIF: Dysfunction in IGF2R Pathway and Associated Perturbations
            in Autophagy and WNT Processes in Beckwith-Wiedemann Syndrome Cell
            Lines.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 14061)
  AUTHORS   Vu,T.H., Li,T. and Hoffman,A.R.
  TITLE     Promoter-restricted histone code, not the differentially methylated
            DNA regions or antisense transcripts, marks the imprinting status
            of IGF2R in human and mouse
  JOURNAL   Hum Mol Genet 13 (19), 2233-2245 (2004)
   PUBMED   15294879
REFERENCE   4  (bases 1 to 14061)
  AUTHORS   De Souza,A.T., Hankins,G.R., Washington,M.K., Orton,T.C. and
            Jirtle,R.L.
  TITLE     M6P/IGF2R gene is mutated in human hepatocellular carcinomas with
            loss of heterozygosity
  JOURNAL   Nat Genet 11 (4), 447-449 (1995)
   PUBMED   7493029
REFERENCE   5  (bases 1 to 14061)
  AUTHORS   Xu,Y., Goodyer,C.G., Deal,C. and Polychronakos,C.
  TITLE     Functional polymorphism in the parental imprinting of the human
            IGF2R gene
  JOURNAL   Biochem Biophys Res Commun 197 (2), 747-754 (1993)
   PUBMED   8267611
  REMARK    GeneRIF: Imprinting of IGF2R gene in human is polymorphic, with a
            minority of individuals showing exclusive expression from the
            maternal allele.
REFERENCE   6  (bases 1 to 14061)
  AUTHORS   Ogawa,O., McNoe,L.A., Eccles,M.R., Morison,I.M. and Reeve,A.E.
  TITLE     Human insulin-like growth factor type I and type II receptors are
            not imprinted
  JOURNAL   Hum Mol Genet 2 (12), 2163-2165 (1993)
   PUBMED   8111387
REFERENCE   7  (bases 1 to 14061)
  AUTHORS   Kalscheuer,V.M., Mariman,E.C., Schepens,M.T., Rehder,H. and
            Ropers,H.H.
  TITLE     The insulin-like growth factor type-2 receptor gene is imprinted in
            the mouse but not in humans
  JOURNAL   Nat Genet 5 (1), 74-78 (1993)
   PUBMED   8220428
REFERENCE   8  (bases 1 to 14061)
  AUTHORS   Antoniades,H.N., Galanopoulos,T., Neville-Golden,J. and Maxwell,M.
  TITLE     Expression of insulin-like growth factors I and II and their
            receptor mRNAs in primary human astrocytomas and meningiomas; in
            vivo studies using in situ hybridization and immunocytochemistry
  JOURNAL   Int J Cancer 50 (2), 215-222 (1992)
   PUBMED   1370435
REFERENCE   9  (bases 1 to 14061)
  AUTHORS   Oshima,A., Nolan,C.M., Kyle,J.W., Grubb,J.H. and Sly,W.S.
  TITLE     The human cation-independent mannose 6-phosphate receptor. Cloning
            and sequence of the full-length cDNA and expression of functional
            receptor in COS cells
  JOURNAL   J Biol Chem 263 (5), 2553-2562 (1988)
   PUBMED   2963003
REFERENCE   10 (bases 1 to 14061)
  AUTHORS   Morgan,D.O., Edman,J.C., Standring,D.N., Fried,V.A., Smith,M.C.,
            Roth,R.A. and Rutter,W.J.
  TITLE     Insulin-like growth factor II receptor as a multifunctional binding
            protein
  JOURNAL   Nature 329 (6137), 301-307 (1987)
   PUBMED   2957598
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL035691.17 and AL353625.5.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Feb 27, 2020 this sequence version replaced NM_000876.3.
            
            Summary: This gene encodes a receptor for both insulin-like growth
            factor 2 and mannose 6-phosphate. The binding sites for each ligand
            are located on different segments of the protein. This receptor has
            various functions, including in the intracellular trafficking of
            lysosomal enzymes, the activation of transforming growth factor
            beta, and the degradation of insulin-like growth factor 2. Mutation
            or loss of heterozygosity of this gene has been association with
            risk of hepatocellular carcinoma. The orthologous mouse gene is
            imprinted and shows exclusive expression from the maternal allele;
            however, imprinting of the human gene may be polymorphic, as only a
            minority of individuals showed biased expression from the maternal
            allele (PMID:8267611). [provided by RefSeq, Nov 2015].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y00285.1, J03528.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            imprinted gene         :: PMID: 8267611
            MANE Ensembl match     :: ENST00000356956.6/ ENSP00000349437.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-314               AL035691.17        43692-44005         c
            315-454             AL035691.17        21764-21903         c
            455-579             AL035691.17        3953-4077           c
            580-678             AL035691.17        2302-2400           c
            679-811             AL353625.5         11586-11718
            812-941             AL353625.5         14199-14328
            942-1047            AL353625.5         16564-16669
            1048-1210           AL353625.5         19565-19727
            1211-1376           AL353625.5         19956-20121
            1377-1480           AL353625.5         21433-21536
            1481-1645           AL353625.5         27574-27738
            1646-1786           AL353625.5         30162-30302
            1787-1930           AL353625.5         31528-31671
            1931-2068           AL353625.5         32759-32896
            2069-2216           AL353625.5         33512-33659
            2217-2394           AL353625.5         34173-34350
            2395-2510           AL353625.5         34806-34921
            2511-2679           AL353625.5         35389-35557
            2680-2859           AL353625.5         37487-37666
            2860-2961           AL353625.5         43438-43539
            2962-3063           AL353625.5         45037-45138
            3064-3256           AL353625.5         45920-46112
            3257-3427           AL353625.5         47561-47731
            3428-3571           AL353625.5         48517-48660
            3572-3747           AL353625.5         48767-48942
            3748-3835           AL353625.5         49546-49633
            3836-4051           AL353625.5         50429-50644
            4052-4182           AL353625.5         51415-51545
            4183-4280           AL353625.5         51818-51915
            4281-4417           AL353625.5         55263-55399
            4418-4608           AL353625.5         56882-57072
            4609-4735           AL353625.5         58924-59050
            4736-4855           AL353625.5         59779-59898
            4856-5112           AL353625.5         60227-60483
            5113-5331           AL353625.5         60771-60989
            5332-5481           AL353625.5         62861-63010
            5482-5643           AL353625.5         65215-65376
            5644-5851           AL353625.5         66594-66801
            5852-5998           AL353625.5         67143-67289
            5999-6233           AL353625.5         70964-71198
            6234-6370           AL353625.5         72009-72145
            6371-6485           AL353625.5         75047-75161
            6486-6632           AL353625.5         76121-76267
            6633-6820           AL353625.5         76930-77117
            6821-7007           AL353625.5         83453-83639
            7008-7160           AL353625.5         89533-89685
            7161-7230           AL353625.5         90760-90829
            7231-14061          AL353625.5         91688-98518
FEATURES             Location/Qualifiers
     source          1..14061
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6q25.3"
     gene            1..14061
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="insulin like growth factor 2 receptor"
                     /db_xref="GeneID:3482"
                     /db_xref="HGNC:HGNC:5467"
                     /db_xref="MIM:147280"
     exon            1..314
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..7641
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="cation-independent mannose-6-phosphate receptor;
                     IGF-II receptor; M6P/IGF2 receptor; CI Man-6-P receptor;
                     300 kDa mannose 6-phosphate receptor; insulin-like growth
                     factor II receptor"
                     /codon_start=1
                     /product="cation-independent mannose-6-phosphate receptor
                     precursor"
                     /protein_id="NP_000867.3"
                     /db_xref="CCDS:CCDS5273.1"
                     /db_xref="GeneID:3482"
                     /db_xref="HGNC:HGNC:5467"
                     /db_xref="MIM:147280"
                     /translation="MGAAAGRSPHLGPAPARRPQRSLLLLQLLLLVAAPGSTQAQAAP
                     FPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLR
                     SATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAA
                     CKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTL
                     RDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCD
                     GHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQ
                     QDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQV
                     KAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTG
                     EVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTE
                     TEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSY
                     SDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEG
                     ENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVA
                     KSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFP
                     EYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMD
                     NSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTG
                     PVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSF
                     LWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGT
                     MPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAK
                     GTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTD
                     LAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSE
                     GNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDG
                     CEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVC
                     GKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCH
                     KVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDLTECSFKDGAGNS
                     FDLSSLSRYSDNWEAITGTGDPEHYLINVCKSLAPQAGTEPCPPEAAACLLGGSKPVN
                     LGRVRDGPQWRDGIIVLKYVDGDLCPDGIRKKSTTIRFTCSESQVNSRPMFISAVEDC
                     EYTFAWPTATACPMKSNEHDDCQVTNPSTGHLFDLSSLSGRAGFTAAYSEKGLVYMSI
                     CGENENCPPGVGACFGQTRISVGKANKRLRYVDQVLQLVYKDGSPCPSKSGLSYKSVI
                     SFVCRPEARPTNRPMLISLDKQTCTLFFSWHTPLACEQATECSVRNGSSIVDLSPLIH
                     RTGGYEAYDESEDDASDTNPDFYINICQPLNPMHGVPCPAGAAVCKVPIDGPPIDIGR
                     VAGPPILNPIANEIYLNFESSTPCLADKHFNYTSLIAFHCKRGVSMGTPKLLRTSECD
                     FVFEWETPVVCPDEVRMDGCTLTDEQLLYSFNLSSLSTSTFKVTRDSRTYSVGVCTFA
                     VGPEQGGCKDGGVCLLSGTKGASFGRLQSMKLDYRHQDEAVVLSYVNGDRCPPETDDG
                     VPCVFPFIFNGKSYEECIIESRAKLWCSTTADYDRDHEWGFCRHSNSYRTSSIIFKCD
                     EDEDIGRPQVFSEVRGCDVTFEWKTKVVCPPKKLECKFVQKHKTYDLRLLSSLTGSWS
                     LVHNGVSYYINLCQKIYKGPLGCSERASICRRTTTGDVQVLGLVHTQKLGVIGDKVVV
                     TYSKGYPCGGNKTASSVIELTCTKTVGRPAFKRFDIDSCTYYFSWDSRAACAVKPQEV
                     QMVNGTITNPINGKSFSLGDIYFKLFRASGDMRTNGDNYLYEIQLSSITSSRNPACSG
                     ANICQVKPNDQHFSRKVGTSDKTKYYLQDGDLDVVFASSSKCGKDKTKSVSSTIFFHC
                     DPLVEDGIPEFSHETADCQYLFSWYTSAVCPLGVGFDSENPGDDGQMHKGLSERSQAV
                     GAVLSLLLVALTCCLLALLLYKKERRETVISKLTTCCRRSSNVSYKYSKVNKEEETDE
                     NETEWLMEEIQLPPPRQGKEGQENGHITTKSVKALSSLHGDDQDSEDEVLTIPEVKVH
                     SGRGAGAESSHPVRNAQSNALQEREDDRVGLVRGEKARKGKSSSAQQKTVSSTKLVSF
                     HDDSDEDLLHI"
     exon            315..454
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            455..579
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            580..678
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            679..811
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            812..941
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1047
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1210
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1376
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1480
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1645
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1786
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1930
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2068
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2216
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2394
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2395..2510
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2679
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2680..2859
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2860..2961
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            2962..3063
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3256
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3257..3427
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3428..3571
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3572..3747
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3748..3835
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            3836..4051
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4052..4182
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4280
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4281..4417
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4418..4608
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4609..4735
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4736..4855
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            4856..5112
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5113..5331
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5332..5481
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5482..5643
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5644..5851
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5852..5998
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            5999..6233
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            6234..6370
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            6371..6485
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            6486..6632
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            6633..6820
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            6821..7007
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            7008..7160
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            7161..7230
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     exon            7231..14061
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9089..9094
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="hexamer: AATAAA"
     polyA_site      9108
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="major polyA site"
     regulatory      9414..9419
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="hexamer: AATAAA"
     polyA_site      9440
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
     regulatory      13972..13977
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="hexamer: AATAAA"
     polyA_site      13992
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
     regulatory      14042..14047
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
                     /note="hexamer: AATACA"
     polyA_site      14061
                     /gene="IGF2R"
                     /gene_synonym="CD222; CI-M6PR; CIMPR; M6P-R; M6P/IGF2R;
                     MPR 300; MPR1; MPR300; MPRI"
ORIGIN      
        1 gccgctgtcg ctgtcgccga gcccagtcga gccgcgctca cctcgggctc ccgctccgtc
       61 tccacctccg cctttgccct ggcggcgcga ccccgtcccg ggcgcggccc ccagcagtcg
      121 cgcgccgtta gcctcgcgcc cgccgcgcag tccgggcccg gcgcgatggg ggccgccgcc
      181 ggccggagcc cccacctggg gcccgcgccc gcccgccgcc cgcagcgctc tctgctcctg
      241 ctgcagctgc tgctgctcgt cgctgccccg gggtccacgc aggcccaggc cgccccgttc
      301 cccgagctgt gcagttatac atgggaagct gttgatacca aaaataatgt actttataaa
      361 atcaacatct gtggaagtgt ggatattgtc cagtgcgggc catcaagtgc tgtttgtatg
      421 cacgacttga agacacgcac ttatcattca gtgggtgact ctgttttgag aagtgcaacc
      481 agatctctcc tggaattcaa cacaacagtg agctgtgacc agcaaggcac aaatcacaga
      541 gtccagagca gcattgcctt cctgtgtggg aaaaccctgg gaactcctga atttgtaact
      601 gcaacagaat gtgtgcacta ctttgagtgg aggaccactg cagcctgcaa gaaagacata
      661 tttaaagcaa ataaggaggt gccatgctat gtgtttgatg aagagttgag gaagcatgat
      721 ctcaatcctc tgatcaagct tagtggtgcc tacttggtgg atgactccga tccggacact
      781 tctctattca tcaatgtttg tagagacata gacacactac gagacccagg ttcacagctg
      841 cgggcctgtc cccccggcac tgccgcctgc ctggtaagag gacaccaggc gtttgatgtt
      901 ggccagcccc gggacggact gaagctggtg cgcaaggaca ggcttgtcct gagttacgtg
      961 agggaagagg caggaaagct agacttttgt gatggtcaca gccctgcggt gactattaca
     1021 tttgtttgcc cgtcggagcg gagagagggc accattccca aactcacagc taaatccaac
     1081 tgccgctatg aaattgagtg gattactgag tatgcctgcc acagagatta cctggaaagt
     1141 aaaacttgtt ctctgagcgg cgagcagcag gatgtctcca tagacctcac accacttgcc
     1201 cagagcggag gttcatccta tatttcagat ggaaaagaat atttgtttta tttgaatgtc
     1261 tgtggagaaa ctgaaataca gttctgtaat aaaaaacaag ctgcagtttg ccaagtgaaa
     1321 aagagcgata cctctcaagt caaagcagca ggaagatacc acaatcagac cctccgatat
     1381 tcggatggag acctcacctt gatatatttt ggaggtgatg aatgcagctc agggtttcag
     1441 cggatgagcg tcataaactt tgagtgcaat aaaaccgcag gtaacgatgg gaaaggaact
     1501 cctgtattca caggggaggt tgactgcacc tacttcttca catgggacac ggaatacgcc
     1561 tgtgttaagg agaaggaaga cctcctctgc ggtgccaccg acgggaagaa gcgctatgac
     1621 ctgtccgcgc tggtccgcca tgcagaacca gagcagaatt gggaagctgt ggatggcagt
     1681 cagacggaaa cagagaagaa gcattttttc attaatattt gtcacagagt gctgcaggaa
     1741 ggcaaggcac gagggtgtcc cgaggacgcg gcagtgtgtg cagtggataa aaatggaagt
     1801 aaaaatctgg gaaaatttat ttcctctccc atgaaagaga aaggaaacat tcaactctct
     1861 tattcagatg gtgatgattg tggtcatggc aagaaaatta aaactaatat cacacttgta
     1921 tgcaagccag gtgatctgga aagtgcacca gtgttgagaa cttctgggga aggcggttgc
     1981 ttttatgagt ttgagtggca cacagctgcg gcctgtgtgc tgtctaagac agaaggggag
     2041 aactgcacgg tctttgactc ccaggcaggg ttttcttttg acttatcacc tctcacaaag
     2101 aaaaatggtg cctataaagt tgagacaaag aagtatgact tttatataaa tgtgtgtggc
     2161 ccggtgtctg tgagcccctg tcagccagac tcaggagcct gccaggtggc aaaaagtgat
     2221 gagaagactt ggaacttggg tctgagtaat gcgaagcttt catattatga tgggatgatc
     2281 caactgaact acagaggcgg cacaccctat aacaatgaaa gacacacacc gagagctacg
     2341 ctcatcacct ttctctgtga tcgagacgcg ggagtgggct tccctgaata tcaggaagag
     2401 gataactcca cctacaactt ccggtggtac accagctatg cctgcccgga ggagcccctg
     2461 gaatgcgtag tgaccgaccc ctccacgctg gagcagtacg acctctccag tctggcaaaa
     2521 tctgaaggtg gccttggagg aaactggtat gccatggaca actcagggga acatgtcacg
     2581 tggaggaaat actacattaa cgtgtgtcgg cctctgaatc cagtgccggg ctgcaaccga
     2641 tatgcatcgg cttgccagat gaagtatgaa aaagatcagg gctccttcac tgaagtggtt
     2701 tccatcagta acttgggaat ggcaaagacc ggcccggtgg ttgaggacag cggcagcctc
     2761 cttctggaat acgtgaatgg gtcggcctgc accaccagcg atggcagaca gaccacatat
     2821 accacgagga tccatctcgt ctgctccagg ggcaggctga acagccaccc catcttttct
     2881 ctcaactggg agtgtgtggt cagtttcctg tggaacacag aggctgcctg tcccattcag
     2941 acaacgacgg atacagacca ggcttgctct ataagggatc ccaacagtgg atttgtgttt
     3001 aatcttaatc cgctaaacag ttcgcaagga tataacgtct ctggcattgg gaagattttt
     3061 atgtttaatg tctgcggcac aatgcctgtc tgtgggacca tcctgggaaa acctgcttct
     3121 ggctgtgagg cagaaaccca aactgaagag ctcaagaatt ggaagccagc aaggccagtc
     3181 ggaattgaga aaagcctcca gctgtccaca gagggcttca tcactctgac ctacaaaggg
     3241 cctctctctg ccaaaggtac cgctgatgct tttatcgtcc gctttgtttg caatgatgat
     3301 gtttactcag ggcccctcaa attcctgcat caagatatcg actctgggca agggatccga
     3361 aacacttact ttgagtttga aaccgcgttg gcctgtgttc cttctccagt ggactgccaa
     3421 gtcaccgacc tggctggaaa tgagtacgac ctgactggcc taagcacagt caggaaacct
     3481 tggacggctg ttgacacctc tgtcgatggg agaaagagga ctttctattt gagcgtttgc
     3541 aatcctctcc cttacattcc tggatgccag ggcagcgcag tggggtcttg cttagtgtca
     3601 gaaggcaata gctggaatct gggtgtggtg cagatgagtc cccaagccgc ggcgaatgga
     3661 tctttgagca tcatgtatgt caacggtgac aagtgtggga accagcgctt ctccaccagg
     3721 atcacgtttg agtgtgctca gatatcgggc tcaccagcat ttcagcttca ggatggttgt
     3781 gagtacgtgt ttatctggag aactgtggaa gcctgtcccg ttgtcagagt ggaaggggac
     3841 aactgtgagg tgaaagaccc aaggcatggc aacttgtatg acctgaagcc cctgggcctc
     3901 aacgacacca tcgtgagcgc tggcgaatac acttattact tccgggtctg tgggaagctt
     3961 tcctcagacg tctgccccac aagtgacaag tccaaggtgg tctcctcatg tcaggaaaag
     4021 cgggaaccgc agggatttca caaagtggca ggtctcctga ctcagaagct aacttatgaa
     4081 aatggcttgt taaaaatgaa cttcacgggg ggggacactt gccataaggt ttatcagcgc
     4141 tccacagcca tcttcttcta ctgtgaccgc ggcacccagc ggccagtatt tctaaaggag
     4201 acttcagatt gttcctactt gtttgagtgg cgaacgcagt atgcctgccc acctttcgat
     4261 ctgactgaat gttcattcaa agatggggct ggcaactcct tcgacctctc gtccctgtca
     4321 aggtacagtg acaactggga agccatcact gggacggggg acccggagca ctacctcatc
     4381 aatgtctgca agtctctggc cccgcaggct ggcactgagc cgtgccctcc agaagcagcc
     4441 gcgtgtctgc tgggtggctc caagcccgtg aacctcggca gggtaaggga cggacctcag
     4501 tggagagatg gcataattgt cctgaaatac gttgatggcg acttatgtcc agatgggatt
     4561 cggaaaaagt caaccaccat ccgattcacc tgcagcgaga gccaagtgaa ctccaggccc
     4621 atgttcatca gcgccgtgga ggactgtgag tacacctttg cctggcccac agccacagcc
     4681 tgtcccatga agagcaacga gcatgatgac tgccaggtca ccaacccaag cacaggacac
     4741 ctgtttgatc tgagctcctt aagtggcagg gcgggattca cagctgctta cagcgagaag
     4801 gggttggttt acatgagcat ctgtggggag aatgaaaact gccctcctgg cgtgggggcc
     4861 tgctttggac agaccaggat tagcgtgggc aaggccaaca agaggctgag atacgtggac
     4921 caggtcctgc agctggtgta caaggatggg tccccttgtc cctccaaatc cggcctgagc
     4981 tataagagtg tgatcagttt cgtgtgcagg cctgaggcca ggccaaccaa taggcccatg
     5041 ctcatctccc tggacaagca gacatgcact ctcttcttct cctggcacac gccgctggcc
     5101 tgcgagcaag cgaccgaatg ttccgtgagg aatggaagct ctattgttga cttgtctccc
     5161 cttattcatc gcactggtgg ttatgaggct tatgatgaga gtgaggatga tgcctccgat
     5221 accaaccctg atttctacat caatatttgt cagccactaa atcccatgca cggagtgccc
     5281 tgtcctgccg gagccgctgt gtgcaaagtt cctattgatg gtccccccat agatatcggc
     5341 cgggtagcag gaccaccaat actcaatcca atagcaaatg agatttactt gaattttgaa
     5401 agcagtactc cttgcttagc ggacaagcat ttcaactaca cctcgctcat cgcgtttcac
     5461 tgtaagagag gtgtgagcat gggaacgcct aagctgttaa ggaccagcga gtgcgacttt
     5521 gtgttcgaat gggagactcc tgtcgtctgt cctgatgaag tgaggatgga tggctgtacc
     5581 ctgacagatg agcagctcct ctacagcttc aacttgtcca gcctttccac gagcaccttt
     5641 aaggtgactc gcgactcgcg cacctacagc gttggggtgt gcacctttgc agtcgggcca
     5701 gaacaaggag gctgtaagga cggaggagtc tgtctgctct caggcaccaa gggggcatcc
     5761 tttggacggc tgcaatcaat gaaactggat tacaggcacc aggatgaagc ggtcgtttta
     5821 agttacgtga atggtgatcg ttgccctcca gaaaccgatg acggcgtccc ctgtgtcttc
     5881 cccttcatat tcaatgggaa gagctacgag gagtgcatca tagagagcag ggcgaagctg
     5941 tggtgtagca caactgcgga ctacgacaga gaccacgagt ggggcttctg cagacactca
     6001 aacagctacc ggacatccag catcatattt aagtgtgatg aagatgagga cattgggagg
     6061 ccacaagtct tcagtgaagt gcgtgggtgt gatgtgacat ttgagtggaa aacaaaagtt
     6121 gtctgccctc caaagaagtt ggagtgcaaa ttcgtccaga aacacaaaac ctacgacctg
     6181 cggctgctct cctctctcac cgggtcctgg tccctcgtcc acaacggagt ctcgtactat
     6241 ataaatctgt gccagaaaat atataaaggg cccctgggct gctctgaaag ggccagcatt
     6301 tgcagaagga ccacaactgg tgacgtccag gtcctgggac tcgttcacac gcagaagctg
     6361 ggtgtcatag gtgacaaagt tgttgtcacg tactccaaag gttatccgtg tggtggaaat
     6421 aagaccgcat cctccgtgat agaattgacc tgtacaaaga cggtgggcag acctgcattc
     6481 aagaggtttg atatcgacag ctgcacttac tacttcagct gggactcccg ggctgcctgc
     6541 gccgtgaagc ctcaggaggt gcagatggtg aatgggacca tcaccaaccc tataaatggc
     6601 aagagcttca gcctcggaga tatttatttt aagctgttca gagcctctgg ggacatgagg
     6661 accaatgggg acaactacct gtatgagatc caactttcct ccatcacaag ctccagaaac
     6721 ccggcgtgct ctggagccaa catatgccag gtgaagccca acgatcagca cttcagtcgg
     6781 aaagttggaa cctctgacaa gaccaagtac taccttcaag acggcgatct cgatgtcgtg
     6841 tttgcctctt cctctaagtg cggaaaggat aagaccaagt ctgtttcttc caccatcttc
     6901 ttccactgtg accctctggt ggaggacggg atccccgagt tcagtcacga gactgccgac
     6961 tgccagtacc tcttctcttg gtacacctca gccgtgtgtc ctctgggggt gggctttgac
     7021 agcgagaatc ccggggacga cgggcagatg cacaaggggc tgtcagaacg gagccaggca
     7081 gtcggcgcgg tgctcagcct gctgctggtg gcgctcacct gctgcctgct ggccctgttg
     7141 ctctacaaga aggagaggag ggaaacagtg ataagtaagc tgaccacttg ctgtaggaga
     7201 agttccaacg tgtcctacaa atactcaaag gtgaataagg aagaagagac agatgagaat
     7261 gaaacagagt ggctgatgga agagatccag ctgcctcctc cacggcaggg aaaggaaggg
     7321 caggagaacg gccatattac caccaagtca gtgaaagccc tcagctccct gcatggggat
     7381 gaccaggaca gtgaggatga ggttctgacc atcccagagg tgaaagttca ctcgggcagg
     7441 ggagctgggg cagagagctc ccacccagtg agaaacgcac agagcaatgc ccttcaggag
     7501 cgtgaggacg atagggtggg gctggtcagg ggtgagaagg cgaggaaagg gaagtccagc
     7561 tctgcacagc agaagacagt gagctccacc aagctggtgt ccttccatga cgacagcgac
     7621 gaggacctct tacacatctg actccgcagt gcctgcaggg gagcacggag ccgcgggaca
     7681 gccaagcacc tccaaccaaa taagacttcc actcgatgat gcttctataa ttttgccttt
     7741 aacagaaact ttcaaaaggg aagagttttt gtgatggggg agagggtgaa ggaggtcagg
     7801 ccccactcct tcctgattgt ttacagtcat tggaataagg catggctcag atcggccaca
     7861 gggcggtacc ttgtgcccag ggttttgccc caagtcctca tttaaaagca taaggccgga
     7921 cgcatctcaa aacagagggc tgcattcgaa gaaacccttg ctgctttagt cccgataggg
     7981 tatttgaccc cgatatattt tagcatttta attctctccc cctatttatt gactttgaca
     8041 attactcagg tttgagaaaa aggaaaaaaa aacagccacc gtttcttcct gccagcaggg
     8101 gtgtgatgta ccagtttgtc catcttgaga tggtgaggct gtcagtgtat ggggcagctt
     8161 ccggcgggat gttgaactgg tcattaatgt gtcccctgag ttggagctca ttctgtctct
     8221 tttctctttt gctttctgtt tcttaagggc acacacacgt gcgtgcgagc acacacacac
     8281 atacgtgcac agggtccccg agtgcctagg ttttggagag tttgcctgtt ctatgccttt
     8341 agtcaggaat ggctgcacct ttttgcatga tatcttcaag cctgggcgta cagagcacat
     8401 ttgtcagtat ttttgccggc tggtgaattc aaacaacctg cccaaagatt gatttgtgtg
     8461 tttgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgagtg gagttgaggt gtcagagaaa
     8521 atgaattttt tccagatttg gggtataggt ctcatctctt caggttctca tgataccacc
     8581 tttactgtgc ttattttttt aagaaaaaag tgttgatcaa ccattcgacc tataagaagc
     8641 cttaatttgc acagtgtgtg acttacagaa actgcatgaa aaatcatggg ccagagcctc
     8701 ggccctagca ttgcacttgg cctcatgctg gagggaggct gggcgggtac agcgcggagg
     8761 aggagggagg ccaggcgggc atggcgtgga ggaggaggga ggccgggcgg tcacagcatg
     8821 gaggaggagg gaggcgctgc tggtgttctt attctggcgg cagcgccttt cctgccatgt
     8881 ttagtgaatg acttttctcg cattgtagaa ttgtatatag actctggtgt tctattgctg
     8941 agaagcaaac cgccctgcag catccctcag cctgtaccgg tttggctggc ttgtttgatt
     9001 tcaacatgag tgtatttttt aaaattgatt tttctcttca tttttttttc aatcaacttt
     9061 actgtaatat aaagtattca acaatttcaa taaaagataa attattaatt gggtgttacc
     9121 attttttcct tgatagtgag acgttcccga gcgagttacc catctgcctg cctgtctttt
     9181 ctttctgtta agtgactgaa tttgggtttt aactctggtg ttctcgttga ccctttatga
     9241 ggcagcactt tcatttttct ccagagtctc ctggtcgtag gtgttaactt tgggtccaat
     9301 ctgccttccc ttggctcttt ctagatccga tttctttacc ttctccaggc caacctcggg
     9361 gtgtggtcct gttcatcaaa acaatgaaca tggagtttag agtccagtga gtcaataaag
     9421 cttttttttg tgcaacctga tctaacatgg agatgttttc tcttgagtaa actcactgag
     9481 ttttccatct taaattactc agcagtgact gagagctacc tgcatggaag caggaagtta
     9541 ctccagtgtt ataaacaaac ttcttagact caacatccta ttctccatcc cttttttttt
     9601 cctgtagagt ccaaaaacct caaccgtctc atttttaaat tatccaattg gagttacctt
     9661 tttaaaaaag ttattcttaa ggactttcca atacctctcc tgaggaagac atgtcaggtc
     9721 ttctaaaagt ttacattatg accaaagaaa gatgctggtc ctcaggcatt ctacccaggg
     9781 ggctgttctc caggccattc ccacctcctg ctaagaccat ggggagccct ctctgtaagg
     9841 aggggcatat gcagggacct gcccatcccc ttggtaagct ggatggcaaa aaggcatgtt
     9901 gtctgcacca ctggctgcct gctaatgtcg ctgtcagtgg ggaaggagaa gtgacaacac
     9961 gtttgagtgc atttgctttg actcttagaa acccaagcct ctgaaaaaag agtaactact
    10021 tgccagctgt tgttacagat gatattttta ggaaaacatc ccgtgacagc aaatcagaat
    10081 tggactcttt ttcagagaaa tgattttatt gatggagtac aacctgggta tttagcttcc
    10141 tttcaacaaa attttttgtg cccctttctt gagactgtcc atgaatgaca gagacataga
    10201 ataagaactg gggtgctaaa gatggaatag gcaaacccca caccaaggaa atccacagtg
    10261 aagtggaaat ctggttctta tgaacatttt aagagcatct gaagcctgta cttcaccaac
    10321 cctaaaataa tacgtaacac gagatgattc ctcaggaagg aacatataga catacagaca
    10381 ggagacaaca tatagacatt agaacttaca ggacaaagaa ctctttttcc ctgaatcatt
    10441 tgagatgaag tttcttccca tcaccaggca ttcctacaaa caaggacctt cacacgacta
    10501 agatgccacc tggtgattaa agaacacttt gggctggtcc gatccattgt acaagttaaa
    10561 gcactgatgg gtacacaggt cttacccctg ttggcgatcg ggtcacaagg agccagtgtg
    10621 tgtgtcacca ggaggttgta tggacgagac tggatttctg gaaatatcct ttactgactc
    10681 tgaagaatcc catggctcag ggaggtacac tcatgtcctt tcttacttct ccggttccac
    10741 tctgttgact agtagttggc ctcttgagcc atacttgctg tcagttctgg acattgttct
    10801 gtgagaatgg ggtcaacggg cagtcgtggt gcaggtgagc ttgtgtgcaa ggcggcaaga
    10861 tagccacatt gagttgggga cagtatggcc tgggggtgtt ggataggtaa ggcagaagca
    10921 agcccagaac ttggagcctg ttgtgactgt cacagtaagg agtttgaagt cctgaaagca
    10981 gttgagagct gtaggagggc cagattgggc ttttgagcaa gatagtctag atgaaagtaa
    11041 agagatggag acgcttcagc aaccagatgg gaggttgggc atgggagctg tggctgtgct
    11101 gagctgagaa gcctcagact gcctgcgagg ctctctctgg gaggaagtca ggtctttctt
    11161 tccttcgttt ccttcctttc attcctttcc tttccttcct ttttcctctt tctttctttc
    11221 cttttctctc tctctctttt tctttctctc tttctttcga gatggagtct cgctctgttg
    11281 ccaggctgga gtgcagtggc atgatctcgg ctcactgcaa tctctgcctc ccgggttcaa
    11341 gggattctcc tgcctcagcc tccctagtag ctgggattaa aggcacgcac tgccacgccc
    11401 ggctaatttt tgtattttta atagcgacag ggtttcaccg tgttggccag gatggtctcg
    11461 atctcctgac ctcatgatcc acctgcctcg gcctccgaaa gtgctgggat tacaggcgtg
    11521 agccaccgtg cccagccagg tctttttctt aaagagggac agactgaagg taggctgtga
    11581 atggtcagtt atttgtattt ctttaccttt tatgctatct tgtagtttga ccagtttgca
    11641 aaacaaattg aataaaaagt aattgataat gttgttttga tgctcagtgt ttgagggaaa
    11701 cacaatctag tgaatggggt tattggttgt cacacctggg agagtgaaaa tgaggggctc
    11761 acaacccagg tgaggtcatc tggtgccact cagccccatc ccagagaaag cagccttggg
    11821 atgctggcct cggtgacaac caagaagtga tggtgggttg ctagagacag ggtggagcac
    11881 agagccctgg aaggaagcag gaagtcaggt tcaagaaagg acttgtgacc tcacccttgg
    11941 cttcagggtt ttatttttct ttcttttaaa acattttgag acaacatgta gacattcaaa
    12001 cttacagaac aaagaactat tttttccctg aatcatttga gactaagttc cctcctatca
    12061 ccagacattt ctacaaatga ggaccttcac aggactaagg tgccaccatc agaaccacaa
    12121 tatgtgggga cggtactgcc agctaagcct tagtgctgtt tcggtgttga cagctgtcac
    12181 aatgatgccc ttttcagtag aggagcctgt gatggtcacg tgttgcaggt gatcattgtg
    12241 ccatttggtt tacttctgtc tggaaagttt ctcctttctg taacctccat gaccttgaca
    12301 catgaggtca ctcttctcac ccgccccacc tctgggaggg tgcctgattt gccctgcccc
    12361 acccagcggc tttaggactc agctcttcag gaacaattag ggagagggcc cttgggtcta
    12421 actgcaaaat catacttgaa ctagaaaatc ccgttggcat aggtatggat tgtcatatag
    12481 aaacattttt cgcagtgtgc cccgtggaac acttgttctg tatgttgtta acagatgttt
    12541 tgcaaaaaat gaaaaggacc tgagctctaa taagtttggg aaatgctgaa ttgaagtgaa
    12601 acagcttttc ttggtgtgag acctttcaga gtctttaaag gagagttgct gaccacacgt
    12661 gaaatcacaa tagaaaatgg ccagcaggcc tccaggtagg cagcaattcc tagacatttg
    12721 cctgtgttcc ctgggggagc tggtggcctg tgaccatcca ctgggaaatt cccttctgtg
    12781 gcgaggttct gttgttttcc agaggctccc acggagcatg ctgggtgggt ggtctgtatg
    12841 agaccacacc gttgatgagc agtgaggccc aaacaggtat atcaaaaaat gctcagcatc
    12901 gctgatcatc agggaaatgc acatcataaa cacagtgaga cgttgcctca cacctgccag
    12961 aatggctact gtcagacgaa agacaacaag tgtgggtgag gatgtggaga aaagcgaaca
    13021 cttgtccacc tttggtgaga atgtaaattg gtatagccat tatggaaaac aggaagttcc
    13081 tgaaaaaatt aagaacagct accaggaatc ccacatctgg gtgtatatcc aaaagaaatg
    13141 aagtcagtac cttgaagaga tctctgcagc ccctgttcat tgcagcatta ttcacaatag
    13201 ccaagatagg gaaaaagcct cagtgtctac tgacaaataa agatggatca agaaaatgca
    13261 tgtatgtata cacacacaca gtggaatacc aagtcttgca gaagaaggaa atcctgtcat
    13321 ttgtgacaac atggatgagc tgagagaaca ttatgctaag tgaaataagc cagacacaga
    13381 aagaaaaata ccagatgatc tcacttatat gtggaatcta aaaaggttgg actcagaagc
    13441 agagagtgga atggtggtta ccaaaggcca gagggtgcag gaagtgagca gatgttggtg
    13501 aaagggtgca gaggttcagc tatgcaacat gaatgaattc tggagatcca ctgtgcagca
    13561 tggtgactat gatactgctt tgtgtattta aaattttcag agagtagatc ttgtgttctt
    13621 tcccctctcc aaataaaagg aaattatttg aggtgatgga tatgtttaac tagcttgact
    13681 ggggcaatga ttttgtaatg ataagtatct caaaacatca tgttgtacaa cataagtata
    13741 caattgaccc ttgaacaata caggtttgaa ctctgtgggt ccacttacat gcggtttttt
    13801 ttttctgtaa aagttacacc cgatgcgtca gccccttctt ctacctcttc cacctctggc
    13861 acccttggca cagcaagacc aaccccccac ttcctcctcc tcctcctcag cctactcagg
    13921 gtaaagacaa ggatgaagac ctttatgatg atccacttcc acttaatata taataaatat
    13981 attttctcct catgattttc ttaaaacttt ttctgtattt tattgtaaga atacagtata
    14041 taatacatac aacatcgaaa a
//
