LOCUS       XM_047435142            8446 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens insulin like growth factor 2 mRNA binding
            protein 1 (IGF2BP1), transcript variant X8, mRNA.
ACCESSION   XM_047435142
VERSION     XM_047435142.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8446
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..8446
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /note="insulin like growth factor 2 mRNA binding protein
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 9 ESTs, 1846 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
     CDS             57..1745
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 1 isoform X7"
                     /protein_id="XP_047291098.1"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
                     /translation="MFAHRHQGALRTPRSTGMSAGSFSWCGGKLPKTDCFGGWSGFLS
                     WLLRGPPRLFPLEDRARLCLFSRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVN
                     TESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFG
                     SRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKID
                     VHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFV
                     GRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKK
                     VREAYENDVAAMSSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMAPEQEM
                     VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFK
                     AQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVV
                     PRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK"
ORIGIN      
        1 actgcgcagc ggccgccact tatggacacg cagacgcttg cggggctggt gcccagatgt
       61 ttgcccatcg tcatcagggg gcactaagga ccccgaggag cacggggatg tctgccgggt
      121 ccttctcatg gtgcggtggg aagctgccga agacagattg ctttggaggc tggtctggtt
      181 tcctctcctg gctcctgaga gggccacctc ggctgttccc tctggaggac agagcccgac
      241 tctgtctgtt ttcaaggagc cggaaaattc aaatccgaaa tattccaccc cagctccgat
      301 gggaagtact ggacagcctg ctggctcagt atggtacagt agagaactgt gagcaagtga
      361 acaccgagag tgagacggca gtggtgaatg tcacctattc caaccgggag cagaccaggc
      421 aagccatcat gaagctgaat ggccaccagt tggagaacca tgccctgaag gtctcctaca
      481 tccccgatga gcagatagca cagggacctg agaatgggcg ccgagggggc tttggctctc
      541 ggggtcagcc ccgccagggc tcacctgtgg cagcgggggc cccagccaag cagcagcaag
      601 tggacatccc ccttcggctc ctggtgccca cccagtatgt gggtgccatt attggcaagg
      661 agggggccac catccgcaac atcacaaaac agacccagtc caagatagac gtgcatagga
      721 aggagaacgc aggtgcagct gaaaaagcca tcagtgtgca ctccacccct gagggctgct
      781 cctccgcttg taagatgatc ttggagatta tgcataaaga ggctaaggac accaaaacgg
      841 ctgacgaggt tcccctgaag atcctggccc ataataactt tgtagggcgt ctcattggca
      901 aggaaggacg gaacctgaag aaggtagagc aagataccga gacaaaaatc accatctcct
      961 cgttgcaaga ccttaccctt tacaaccctg agaggaccat cactgtgaag ggggccatcg
     1021 agaattgttg cagggccgag caggaaataa tgaagaaagt tcgggaggcc tatgagaatg
     1081 atgtggctgc catgagctct cacctgatcc ctggcctgaa cctggctgct gtaggtcttt
     1141 tcccagcttc atccagcgca gtcccgccgc ctcccagcag cgttactggg gctgctccct
     1201 atagctcctt tatggctccc gagcaggaga tggtgcaggt gtttatcccc gcccaggcag
     1261 tgggcgccat catcggcaag aaggggcagc acatcaaaca gctctcccgg tttgccagcg
     1321 cctccatcaa gattgcacca cccgaaacac ctgactccaa agttcgtatg gttatcatca
     1381 ctggaccgcc agaggcccaa ttcaaggctc agggaagaat ctatggcaaa ctcaaggagg
     1441 agaacttctt tggtcccaag gaggaagtga agctggagac ccacatacgt gtgccagcat
     1501 cagcagctgg ccgggtcatt ggcaaaggtg gaaaaacggt gaacgagttg cagaatttga
     1561 cggcagctga ggtggtagta ccaagagacc agacccctga tgagaacgac caggtcatcg
     1621 tgaaaatcat cggacatttc tatgccagtc agatggctca acggaagatc cgagacatcc
     1681 tggcccaggt taagcagcag catcagaagg gacagagtaa ccaggcccag gcacggagga
     1741 agtgaccagc ccctccctgt cccttcgagt ccaggacaac aacgggcaga aatcgagagt
     1801 gtgctctccc cggcaggcct gagaatgagt gggaatccgg gacacctggg ccgggctgta
     1861 gatcaggttt gcccacttga ttgagaaaga tgttccagtg aggaaccctg atctctcagc
     1921 cccaaacacc cacccaattg gcccaacact gtctgcccct cggggtgtca gaaattctag
     1981 cgcaaggcac ttttaaacgt ggattgttta aagaagctct ccaggcccca ccaagagggt
     2041 ggatcacacc tcagtgggaa gaaaaataaa atttccttca ggttttaaaa acatgcagag
     2101 aggtgtttta atcagcctta aaggatggtt catttcttga ccttaatgtt tttccaatct
     2161 tcttccccct acttgggtaa ttgattaaaa tacctccatt tacggcctct ttctatattt
     2221 acactaattt ttttatcttt attgctacca gaaaaaaatg cgaacgaatg cattgctttg
     2281 cttacagtat tgactcaagg gaaaagaact gtcagtatct gtagattaat tccaatcact
     2341 ccctaaccaa taggtacaat acggaatgaa gaagagggga aaatggggag aaagatggtt
     2401 aaaatacata ataatccacg tttaaaagga gcgcacttgt ggctgatcta tgccagatca
     2461 ccatcttcaa attggcacaa ctgaaatttc cccactctgt tggggcttcc ccaccacatt
     2521 catgtccctc tcccgtgtag gtttcacatt atgtccaggt gcacataggt ggtattgaat
     2581 gctcagcagg gtaggggctg accactgtcc ctgattccca tcgttctcag gcggatttta
     2641 tattttttta aagtctattt taatgattgg atatgagcac tgggaagggg acgctaactc
     2701 cccttgataa agtctcggtt ccatggagga cttgagtggc cccaaaggct gccacggtgc
     2761 cctcacccca gcccatgtgc tcccataagg gctggttcct agaggcaggg gttgtggggc
     2821 actcccagcc acggcactgt taccttggtg gtgggacttg gaacccaacc ctgagctccc
     2881 gataaagcta aagtccatca tctggcaaat tcagtaaatt ggagagtact tgcttctgtt
     2941 tgtatctgag aggaattttt aactgacggc ttctgtctcc atgaatcatt atcagcatga
     3001 tgaaaggtgt gtctaaaaaa caattcagaa taccagcagc attgtacagc aaggggtaaa
     3061 taagcttaat ttattaattt accaggctta attaagatcc catggagtgt ttagcccttg
     3121 tgggagacag aagccatcag ttaaatgagg ttaggcctct cctcctaata tactgattga
     3181 caatgcatat tagccaggta atgcacttta gctaccctgg acaatgctat caagtgtgct
     3241 gggaagggag gaaggcctct ctacatatgg aaaagcccat gcgtggagtt cccctccttt
     3301 caacattgca acaacagtaa caacaagaca accgcaacat gtgggcgtag tcaggcaatg
     3361 ctgtgtgcga agtaaactac ctcaaggtat gaagttacct cagcaattat tttccttttt
     3421 gttcccccca accccattaa aaaaattttt ttttgatttt tgtttttttg cagcttgctg
     3481 atattttata taaaaaagaa aagcaaagca aaagagaagc tgatagtctt gaatatttta
     3541 tttttttaat gaaaagaaaa aacaagaaag ttatgtttca taatttctta caacatgagc
     3601 cagtaaccct ttaggaactc tctatggaga acaggcctgg tgggaaaggc tttgggggct
     3661 gcccccttag gaggaggcta gtgctaagag ggaaggccca ggtttgagag agcccagagg
     3721 ggcagagccc agagccttgt ttggccctga tctctgactt ctagagcccc agctgctggc
     3781 ggctgctgga atatcctacc tgataggatt aaaaggccta gtggagctgg gggctctcag
     3841 tggttaaaca atgcccaaca accaaccagc tggcccttgg tctcctctct ttcctccttt
     3901 ggttaaagag catctcagcc agcttttccc accagtggtg ctgttgagat attttaaaat
     3961 attgcctccg ttttatcgag gagagaaata ataactaaaa aatataccct ttaaaaaaac
     4021 ctatatttct ctgtctaaaa atatgggagc tgagattccg ttcgtggaaa aaagacaagg
     4081 ccaccctctc gccctcagag aggtccacct ggtttgtcat tgcaatgctt ttcatttttt
     4141 ttttttgtta ttgtttcatt tcagttccgt cttgctattc ttcctaatct atatccatag
     4201 atctaagggg caaacagata ctagttaact gcccccacct ctgtctccct gtcttcttta
     4261 gatcggtctg attgatttta aaagtggacc caaacttagg gaattcttga tttagggtgg
     4321 ctggtggcaa ggaggggcag gggatatggg gacgtgactg ggacaggttc ctgccttatc
     4381 attttctccc taggacattc ccttgtagcc cccagaattg tctggcccaa attgaataga
     4441 agcagaaaaa catttaggga taacatcagg ccagtagaat taagcctctc cacctgtccc
     4501 aaccataaaa agggtctccc agctttccat ctctggctct atatgcttta tcccaaaaca
     4561 aagcagataa cgttcagacg tcggccattt agtaatttaa agcgaatttc cagcagcaag
     4621 catgctttga tatctggttc agactatcat caggaagaaa aaaaaatccc acagtacctg
     4681 aaatgtgatt gttgcagtgt tcagtttcct tgggggcctg ctcccttcac accttgagcc
     4741 caagtccttt tccgttggct gattcagctc ccagaagaga cgaggaagtg tgtggcaagg
     4801 gactggaaaa cttcacttgc ttggattagg caaggctcca ctcattgttg atatttgccc
     4861 agcaggaaaa tcatgtaagt tataccacca gaaagcaaaa ggagcatggt ttggtggtta
     4921 aggtttagtg ggatgaagga cctgtcttgg tgggccgggc cctcttgtgc cccgtaggct
     4981 aggtcttagg gcaactcctt gccctcctgc tcagcacctc catttcccca tccttggtga
     5041 gataacaagc tatcgcgaaa agcacttggg agatttggat gatttgagaa gagtgactta
     5101 aaaaaaatgc ttctgtgctc taagatatat atgtgtgtgt gtgtgctaca tatatatttt
     5161 taagaaagga ccatctcttt aggatatatt tttaaattct ttgaaacaca taaccaaaat
     5221 ggtttgattc actgactgac tttgaagctg catctgccag ttacacccca aatggcttta
     5281 atcccctctc gggtctggtt gccttttgca gtttgggttg tggactcagc tcctgtgagg
     5341 ggtctggtta ggagagagcc atttttaagg acagggagtt ttatagccct tttctacttt
     5401 cctcccctcc tcccagtcct tatcaatctt ttttcctttt tcctgacccc ctccttctgg
     5461 aggcagttgg gagctatcct tgtttatgcc tcactattgg cagaaaagac cccatttaaa
     5521 acccagagaa cactggaggg ggatgctcta gttggttctg tgtccatttt cctctgtgcc
     5581 aaagacagac agacagaggc tgagagaggc tgttcctgaa tcaaagcaat agccagcttt
     5641 cgacacatac ctggctgtct gaggaggaag gcctcctgga aactgggagc taagggcgag
     5701 gcccttccct tcagaggctc ctgggggatt agggtgtggt gtttgccaag ccaaggggta
     5761 gggagccgag aaattggtct gtcggctcct ggttgcactt tggggaagga gaggaagttt
     5821 ggggctccag gtagctccct gttgtgggac tgctctgtcc cctgccccta ctgcagagat
     5881 agcactgccg agttcccttc aggcctggca gacgggcagt gaggaggggc ctcagttagc
     5941 tctcaagggt gccttcccct cctcccaacc cagacatacc ctctgccaaa ctgggaacca
     6001 gcagtgctag taactacctc acagagcccc agagggcctg cttgagcctt cttgctccac
     6061 aggagaagct ggtgcctcta ggcaacccct tcctcccacc tctcatcagg ggtgggggtt
     6121 ctcctttctt tcccctgaag tgtttatggg gagatcctag tggctttgcc attcaaacca
     6181 ctcgactgtt tgcctgtttc ttgaaaacca gtagaaggga aacagcacag cctgtcacag
     6241 taattgcagg aagattgaag aaaaatcctc atcaatgcca ggggacataa aagccatttc
     6301 ccttccaaat actcgacaat ttagatgcag aacatttctc tgtattcaga cttagagtaa
     6361 caccagctga aaactgcagt ttctttcctt tggatacata aggcttctct atcggggtac
     6421 gggacaggga ggaggcctca tgtctgaagg gggatttagg ggcgagagcc ccagccctga
     6481 ccctcggtcc tgtgcaccgc tttggggcac agtctgatgg cgcctttgct ggcgccttag
     6541 tatggttgac tccggatgga caaaagaaaa aaaatttttt ttcttgaatg aaatagcagg
     6601 aagctcctcg ggagcatgtg ttttgattaa ccgcaggtga tggatgctac gagtataaat
     6661 ggattaacta cctcaatcct tacagtaaga ttggaactaa gggcagggac tcatgcataa
     6721 gggtatgaat cccagccagg acaagtgagt tgaggcttgt gccacaaaag gtttgtcctt
     6781 ggggaacagg caggcctgcc aggatccccc ccatatcgat tgggctggga gggctggcca
     6841 tgaggtcccc actttctgct ttccttgccc atgtgtcacc cctttggcct ccagcttgtc
     6901 cctctctcac tttctatagc tttgttggac cagatggtga ggaaaggaat ggcctcttcc
     6961 cttctagagg gggctggctg gagtgagacc tggggcttgg cctggaaccc accacacagc
     7021 cccaaagtca ggaagcctgg ggaaaccaga gctgagacct cttcaacagg gtttctttga
     7081 gatcctacac ctccattggg ccctttttca gtcttcaatg ggggcccagt tggctctaga
     7141 aggagaagag gtgaagcagg atcctttgcc ctgggggagt ctgagggcgc ggtccttgga
     7201 ctcattcagg ccgtctttgt agttggggga gttccactgg gcgatcccag cccctcccca
     7261 cccaccctct aatggacctc ctcatagaag ccccatttca cttttgtttt atctacctct
     7321 tagcaaaaca atagataaat taggtagtgg cagctccact tgcttaggtt agggggggaa
     7381 aaagatttct ttttccaaag gaaaaaaata ttaccttgag aatactttcc aaaaaataaa
     7441 attaaaaaaa aaaaaaccaa aaaaaaaaat ttttttttaa aagggagaca ttttccagtg
     7501 accactggat tgttttaatt tcccaagctt ttttttcccc cataaataag tttcactctt
     7561 tggcgatttt cttcacttgt ttaagataac gtgctagcta ttccaacagg taacagcttt
     7621 cacagtctgc ccctggcctg tctcacccca tcccccaccc tattcctgcc agtgagtcct
     7681 tcctgtgctt ctctcccttc tcccctccca gccagctgac ttcagtcacc cctgtccccc
     7741 ctcccctgcc aataagctcc cccaggaata aaggctttgt tttggggatg cttaaatctt
     7801 gactggcact tcccggctgt gggggctggg gagccacttg taacatttct gtgcagattt
     7861 tatgttagcc actgctatgt aaaagcacgt tcaaaatgaa tttcagcaga ttatgtgtta
     7921 ccataatgaa taaacgtcct ctatcaccat ttggagtctc ccttttctcc aggatcttga
     7981 tcctggtccc caaaaccaga gtgaatcaaa agagcttcct cccctgaggc aaagtggatt
     8041 tgtaagcagt tctgaaacat cacttactca gaagagggaa cgatgtattt tgatgagtgc
     8101 aaattgggaa gagctggagg cctactgctt gggacagttt tttttttttt ttttttttta
     8161 aatatgagtg ctagcttatt ctgtaattgc ggcaactttg aaaattgtat tttactggaa
     8221 atctgccagc catcaccacc cgattttgat tgtatccttc ctcccatcct ttaatctgtt
     8281 cattgctttg ggggaggtgg ggcagctggc tcacacgttg gagtttgttc tttgatggat
     8341 gaacgaacac tccagttttc tttcccgtga aggttgtttc agccacaaac cacttcattt
     8401 tgctgtttca atttcaaaat aaaaggaaac ttatattgaa agacaa
//
