LOCUS       XM_047435141            8685 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens insulin like growth factor 2 mRNA binding
            protein 1 (IGF2BP1), transcript variant X6, mRNA.
ACCESSION   XM_047435141
VERSION     XM_047435141.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8685
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..8685
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /note="insulin like growth factor 2 mRNA binding protein
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 10 ESTs, 1890 long SRA reads, 3
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 25 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
     CDS             290..1984
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 1 isoform X6"
                     /protein_id="XP_047291097.1"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
                     /translation="MFAHRHQGALRTPRSTGMSAGSFSWCGGKLPKTDCFGGWSGFLS
                     WLLRGPPRLFPLEDRARLCLFSRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVN
                     TESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFG
                     SRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKID
                     VHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFV
                     GRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKK
                     VREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMAPEQ
                     EMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQ
                     FKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEV
                     VVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK"
ORIGIN      
        1 agtcctccca gacaggatcc ttggtggtag aacattctag accgtgcgga gccctgggga
       61 ggaagacctc cacagagagg gcacttgagg gggggaggag ggccacgttg gggcccttgt
      121 caggggagag actggctgag gaagcgcccg ccaggaagaa gccagctgca gcgcctgttt
      181 cccaccgcag gtcatggttg gcagctaggg ggagacgcgg atccctgagg gctactgcgc
      241 agcggccgcc acttatggac acgcagacgc ttgcggggct ggtgcccaga tgtttgccca
      301 tcgtcatcag ggggcactaa ggaccccgag gagcacgggg atgtctgccg ggtccttctc
      361 atggtgcggt gggaagctgc cgaagacaga ttgctttgga ggctggtctg gtttcctctc
      421 ctggctcctg agagggccac ctcggctgtt ccctctggag gacagagccc gactctgtct
      481 gttttcaagg agccggaaaa ttcaaatccg aaatattcca ccccagctcc gatgggaagt
      541 actggacagc ctgctggctc agtatggtac agtagagaac tgtgagcaag tgaacaccga
      601 gagtgagacg gcagtggtga atgtcaccta ttccaaccgg gagcagacca ggcaagccat
      661 catgaagctg aatggccacc agttggagaa ccatgccctg aaggtctcct acatccccga
      721 tgagcagata gcacagggac ctgagaatgg gcgccgaggg ggctttggct ctcggggtca
      781 gccccgccag ggctcacctg tggcagcggg ggccccagcc aagcagcagc aagtggacat
      841 cccccttcgg ctcctggtgc ccacccagta tgtgggtgcc attattggca aggagggggc
      901 caccatccgc aacatcacaa aacagaccca gtccaagata gacgtgcata ggaaggagaa
      961 cgcaggtgca gctgaaaaag ccatcagtgt gcactccacc cctgagggct gctcctccgc
     1021 ttgtaagatg atcttggaga ttatgcataa agaggctaag gacaccaaaa cggctgacga
     1081 ggttcccctg aagatcctgg cccataataa ctttgtaggg cgtctcattg gcaaggaagg
     1141 acggaacctg aagaaggtag agcaagatac cgagacaaaa atcaccatct cctcgttgca
     1201 agaccttacc ctttacaacc ctgagaggac catcactgtg aagggggcca tcgagaattg
     1261 ttgcagggcc gagcaggaaa taatgaagaa agttcgggag gcctatgaga atgatgtggc
     1321 tgccatgagc ctgcagtctc acctgatccc tggcctgaac ctggctgctg taggtctttt
     1381 cccagcttca tccagcgcag tcccgccgcc tcccagcagc gttactgggg ctgctcccta
     1441 tagctccttt atggctcccg agcaggagat ggtgcaggtg tttatccccg cccaggcagt
     1501 gggcgccatc atcggcaaga aggggcagca catcaaacag ctctcccggt ttgccagcgc
     1561 ctccatcaag attgcaccac ccgaaacacc tgactccaaa gttcgtatgg ttatcatcac
     1621 tggaccgcca gaggcccaat tcaaggctca gggaagaatc tatggcaaac tcaaggagga
     1681 gaacttcttt ggtcccaagg aggaagtgaa gctggagacc cacatacgtg tgccagcatc
     1741 agcagctggc cgggtcattg gcaaaggtgg aaaaacggtg aacgagttgc agaatttgac
     1801 ggcagctgag gtggtagtac caagagacca gacccctgat gagaacgacc aggtcatcgt
     1861 gaaaatcatc ggacatttct atgccagtca gatggctcaa cggaagatcc gagacatcct
     1921 ggcccaggtt aagcagcagc atcagaaggg acagagtaac caggcccagg cacggaggaa
     1981 gtgaccagcc cctccctgtc ccttcgagtc caggacaaca acgggcagaa atcgagagtg
     2041 tgctctcccc ggcaggcctg agaatgagtg ggaatccggg acacctgggc cgggctgtag
     2101 atcaggtttg cccacttgat tgagaaagat gttccagtga ggaaccctga tctctcagcc
     2161 ccaaacaccc acccaattgg cccaacactg tctgcccctc ggggtgtcag aaattctagc
     2221 gcaaggcact tttaaacgtg gattgtttaa agaagctctc caggccccac caagagggtg
     2281 gatcacacct cagtgggaag aaaaataaaa tttccttcag gttttaaaaa catgcagaga
     2341 ggtgttttaa tcagccttaa aggatggttc atttcttgac cttaatgttt ttccaatctt
     2401 cttcccccta cttgggtaat tgattaaaat acctccattt acggcctctt tctatattta
     2461 cactaatttt tttatcttta ttgctaccag aaaaaaatgc gaacgaatgc attgctttgc
     2521 ttacagtatt gactcaaggg aaaagaactg tcagtatctg tagattaatt ccaatcactc
     2581 cctaaccaat aggtacaata cggaatgaag aagaggggaa aatggggaga aagatggtta
     2641 aaatacataa taatccacgt ttaaaaggag cgcacttgtg gctgatctat gccagatcac
     2701 catcttcaaa ttggcacaac tgaaatttcc ccactctgtt ggggcttccc caccacattc
     2761 atgtccctct cccgtgtagg tttcacatta tgtccaggtg cacataggtg gtattgaatg
     2821 ctcagcaggg taggggctga ccactgtccc tgattcccat cgttctcagg cggattttat
     2881 atttttttaa agtctatttt aatgattgga tatgagcact gggaagggga cgctaactcc
     2941 ccttgataaa gtctcggttc catggaggac ttgagtggcc ccaaaggctg ccacggtgcc
     3001 ctcaccccag cccatgtgct cccataaggg ctggttccta gaggcagggg ttgtggggca
     3061 ctcccagcca cggcactgtt accttggtgg tgggacttgg aacccaaccc tgagctcccg
     3121 ataaagctaa agtccatcat ctggcaaatt cagtaaattg gagagtactt gcttctgttt
     3181 gtatctgaga ggaattttta actgacggct tctgtctcca tgaatcatta tcagcatgat
     3241 gaaaggtgtg tctaaaaaac aattcagaat accagcagca ttgtacagca aggggtaaat
     3301 aagcttaatt tattaattta ccaggcttaa ttaagatccc atggagtgtt tagcccttgt
     3361 gggagacaga agccatcagt taaatgaggt taggcctctc ctcctaatat actgattgac
     3421 aatgcatatt agccaggtaa tgcactttag ctaccctgga caatgctatc aagtgtgctg
     3481 ggaagggagg aaggcctctc tacatatgga aaagcccatg cgtggagttc ccctcctttc
     3541 aacattgcaa caacagtaac aacaagacaa ccgcaacatg tgggcgtagt caggcaatgc
     3601 tgtgtgcgaa gtaaactacc tcaaggtatg aagttacctc agcaattatt ttcctttttg
     3661 ttccccccaa ccccattaaa aaaatttttt tttgattttt gtttttttgc agcttgctga
     3721 tattttatat aaaaaagaaa agcaaagcaa aagagaagct gatagtcttg aatattttat
     3781 ttttttaatg aaaagaaaaa acaagaaagt tatgtttcat aatttcttac aacatgagcc
     3841 agtaaccctt taggaactct ctatggagaa caggcctggt gggaaaggct ttgggggctg
     3901 cccccttagg aggaggctag tgctaagagg gaaggcccag gtttgagaga gcccagaggg
     3961 gcagagccca gagccttgtt tggccctgat ctctgacttc tagagcccca gctgctggcg
     4021 gctgctggaa tatcctacct gataggatta aaaggcctag tggagctggg ggctctcagt
     4081 ggttaaacaa tgcccaacaa ccaaccagct ggcccttggt ctcctctctt tcctcctttg
     4141 gttaaagagc atctcagcca gcttttccca ccagtggtgc tgttgagata ttttaaaata
     4201 ttgcctccgt tttatcgagg agagaaataa taactaaaaa atataccctt taaaaaaacc
     4261 tatatttctc tgtctaaaaa tatgggagct gagattccgt tcgtggaaaa aagacaaggc
     4321 caccctctcg ccctcagaga ggtccacctg gtttgtcatt gcaatgcttt tcattttttt
     4381 tttttgttat tgtttcattt cagttccgtc ttgctattct tcctaatcta tatccataga
     4441 tctaaggggc aaacagatac tagttaactg cccccacctc tgtctccctg tcttctttag
     4501 atcggtctga ttgattttaa aagtggaccc aaacttaggg aattcttgat ttagggtggc
     4561 tggtggcaag gaggggcagg ggatatgggg acgtgactgg gacaggttcc tgccttatca
     4621 ttttctccct aggacattcc cttgtagccc ccagaattgt ctggcccaaa ttgaatagaa
     4681 gcagaaaaac atttagggat aacatcaggc cagtagaatt aagcctctcc acctgtccca
     4741 accataaaaa gggtctccca gctttccatc tctggctcta tatgctttat cccaaaacaa
     4801 agcagataac gttcagacgt cggccattta gtaatttaaa gcgaatttcc agcagcaagc
     4861 atgctttgat atctggttca gactatcatc aggaagaaaa aaaaatccca cagtacctga
     4921 aatgtgattg ttgcagtgtt cagtttcctt gggggcctgc tcccttcaca ccttgagccc
     4981 aagtcctttt ccgttggctg attcagctcc cagaagagac gaggaagtgt gtggcaaggg
     5041 actggaaaac ttcacttgct tggattaggc aaggctccac tcattgttga tatttgccca
     5101 gcaggaaaat catgtaagtt ataccaccag aaagcaaaag gagcatggtt tggtggttaa
     5161 ggtttagtgg gatgaaggac ctgtcttggt gggccgggcc ctcttgtgcc ccgtaggcta
     5221 ggtcttaggg caactccttg ccctcctgct cagcacctcc atttccccat ccttggtgag
     5281 ataacaagct atcgcgaaaa gcacttggga gatttggatg atttgagaag agtgacttaa
     5341 aaaaaatgct tctgtgctct aagatatata tgtgtgtgtg tgtgctacat atatattttt
     5401 aagaaaggac catctcttta ggatatattt ttaaattctt tgaaacacat aaccaaaatg
     5461 gtttgattca ctgactgact ttgaagctgc atctgccagt tacaccccaa atggctttaa
     5521 tcccctctcg ggtctggttg ccttttgcag tttgggttgt ggactcagct cctgtgaggg
     5581 gtctggttag gagagagcca tttttaagga cagggagttt tatagccctt ttctactttc
     5641 ctcccctcct cccagtcctt atcaatcttt tttccttttt cctgaccccc tccttctgga
     5701 ggcagttggg agctatcctt gtttatgcct cactattggc agaaaagacc ccatttaaaa
     5761 cccagagaac actggagggg gatgctctag ttggttctgt gtccattttc ctctgtgcca
     5821 aagacagaca gacagaggct gagagaggct gttcctgaat caaagcaata gccagctttc
     5881 gacacatacc tggctgtctg aggaggaagg cctcctggaa actgggagct aagggcgagg
     5941 cccttccctt cagaggctcc tgggggatta gggtgtggtg tttgccaagc caaggggtag
     6001 ggagccgaga aattggtctg tcggctcctg gttgcacttt ggggaaggag aggaagtttg
     6061 gggctccagg tagctccctg ttgtgggact gctctgtccc ctgcccctac tgcagagata
     6121 gcactgccga gttcccttca ggcctggcag acgggcagtg aggaggggcc tcagttagct
     6181 ctcaagggtg ccttcccctc ctcccaaccc agacataccc tctgccaaac tgggaaccag
     6241 cagtgctagt aactacctca cagagcccca gagggcctgc ttgagccttc ttgctccaca
     6301 ggagaagctg gtgcctctag gcaacccctt cctcccacct ctcatcaggg gtgggggttc
     6361 tcctttcttt cccctgaagt gtttatgggg agatcctagt ggctttgcca ttcaaaccac
     6421 tcgactgttt gcctgtttct tgaaaaccag tagaagggaa acagcacagc ctgtcacagt
     6481 aattgcagga agattgaaga aaaatcctca tcaatgccag gggacataaa agccatttcc
     6541 cttccaaata ctcgacaatt tagatgcaga acatttctct gtattcagac ttagagtaac
     6601 accagctgaa aactgcagtt tctttccttt ggatacataa ggcttctcta tcggggtacg
     6661 ggacagggag gaggcctcat gtctgaaggg ggatttaggg gcgagagccc cagccctgac
     6721 cctcggtcct gtgcaccgct ttggggcaca gtctgatggc gcctttgctg gcgccttagt
     6781 atggttgact ccggatggac aaaagaaaaa aaattttttt tcttgaatga aatagcagga
     6841 agctcctcgg gagcatgtgt tttgattaac cgcaggtgat ggatgctacg agtataaatg
     6901 gattaactac ctcaatcctt acagtaagat tggaactaag ggcagggact catgcataag
     6961 ggtatgaatc ccagccagga caagtgagtt gaggcttgtg ccacaaaagg tttgtccttg
     7021 gggaacaggc aggcctgcca ggatcccccc catatcgatt gggctgggag ggctggccat
     7081 gaggtcccca ctttctgctt tccttgccca tgtgtcaccc ctttggcctc cagcttgtcc
     7141 ctctctcact ttctatagct ttgttggacc agatggtgag gaaaggaatg gcctcttccc
     7201 ttctagaggg ggctggctgg agtgagacct ggggcttggc ctggaaccca ccacacagcc
     7261 ccaaagtcag gaagcctggg gaaaccagag ctgagacctc ttcaacaggg tttctttgag
     7321 atcctacacc tccattgggc cctttttcag tcttcaatgg gggcccagtt ggctctagaa
     7381 ggagaagagg tgaagcagga tcctttgccc tgggggagtc tgagggcgcg gtccttggac
     7441 tcattcaggc cgtctttgta gttgggggag ttccactggg cgatcccagc ccctccccac
     7501 ccaccctcta atggacctcc tcatagaagc cccatttcac ttttgtttta tctacctctt
     7561 agcaaaacaa tagataaatt aggtagtggc agctccactt gcttaggtta gggggggaaa
     7621 aagatttctt tttccaaagg aaaaaaatat taccttgaga atactttcca aaaaataaaa
     7681 ttaaaaaaaa aaaaaccaaa aaaaaaaatt tttttttaaa agggagacat tttccagtga
     7741 ccactggatt gttttaattt cccaagcttt tttttccccc ataaataagt ttcactcttt
     7801 ggcgattttc ttcacttgtt taagataacg tgctagctat tccaacaggt aacagctttc
     7861 acagtctgcc cctggcctgt ctcaccccat cccccaccct attcctgcca gtgagtcctt
     7921 cctgtgcttc tctcccttct cccctcccag ccagctgact tcagtcaccc ctgtcccccc
     7981 tcccctgcca ataagctccc ccaggaataa aggctttgtt ttggggatgc ttaaatcttg
     8041 actggcactt cccggctgtg ggggctgggg agccacttgt aacatttctg tgcagatttt
     8101 atgttagcca ctgctatgta aaagcacgtt caaaatgaat ttcagcagat tatgtgttac
     8161 cataatgaat aaacgtcctc tatcaccatt tggagtctcc cttttctcca ggatcttgat
     8221 cctggtcccc aaaaccagag tgaatcaaaa gagcttcctc ccctgaggca aagtggattt
     8281 gtaagcagtt ctgaaacatc acttactcag aagagggaac gatgtatttt gatgagtgca
     8341 aattgggaag agctggaggc ctactgcttg ggacagtttt tttttttttt ttttttttaa
     8401 atatgagtgc tagcttattc tgtaattgcg gcaactttga aaattgtatt ttactggaaa
     8461 tctgccagcc atcaccaccc gattttgatt gtatccttcc tcccatcctt taatctgttc
     8521 attgctttgg gggaggtggg gcagctggct cacacgttgg agtttgttct ttgatggatg
     8581 aacgaacact ccagttttct ttcccgtgaa ggttgtttca gccacaaacc acttcatttt
     8641 gctgtttcaa tttcaaaata aaaggaaact tatattgaaa gacaa
//
