LOCUS       XM_047435140            8787 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens insulin like growth factor 2 mRNA binding
            protein 1 (IGF2BP1), transcript variant X4, mRNA.
ACCESSION   XM_047435140
VERSION     XM_047435140.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8787
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..8787
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /note="insulin like growth factor 2 mRNA binding protein
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 11 ESTs, 1948 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
     CDS             362..2086
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 1 isoform X4"
                     /protein_id="XP_047291096.1"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
                     /translation="MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDC
                     PDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLA
                     QYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIA
                     QGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATI
                     RNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADE
                     VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE
                     NCCRAEQEIMKKVREAYENDVAAMSSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAA
                     PYSSFMAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRM
                     VIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVN
                     ELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQS
                     NQAQARRK"
ORIGIN      
        1 cgctccattt tttttcaagt cgattttatt tagaggcggc gccagggcgg ccgcggagaa
       61 acgtgacaca ccagccctct cggaggggtt tcggaccgaa gggaagaagc tgcgccgtgt
      121 cgtccgtctc cctgcgcgcc gcgggcactt ctcctgggct ctccccgaac tctcccgcga
      181 cctctgcgcg ccctcaggcc gccttccccg ccctgggctc gggacaactt ctggggtggg
      241 gtgcaaagaa agtttgcggc tcctgccgcc ggcctctccg cctcttggcc taggaggctc
      301 gccgcccgcg cccgctcgtt cggccttgcc cgggaccgcg tcctgccccg agaccgccac
      361 catgaacaag ctttacatcg gcaacctcaa cgagagcgtg acccccgcgg acttggagaa
      421 agtgtttgcg gagcacaaga tctcctacag cggccagttc ttggtcaaat ccggctacgc
      481 cttcgtggac tgcccggacg agcactgggc gatgaaggcc atcgaaactt tctccgggaa
      541 agtagaatta caaggaaaac gcttagagat tgaacattcg gtgcccaaaa aacaaaggag
      601 ccggaaaatt caaatccgaa atattccacc ccagctccga tgggaagtac tggacagcct
      661 gctggctcag tatggtacag tagagaactg tgagcaagtg aacaccgaga gtgagacggc
      721 agtggtgaat gtcacctatt ccaaccggga gcagaccagg caagccatca tgaagctgaa
      781 tggccaccag ttggagaacc atgccctgaa ggtctcctac atccccgatg agcagatagc
      841 acagggacct gagaatgggc gccgaggggg ctttggctct cggggtcagc cccgccaggg
      901 ctcacctgtg gcagcggggg ccccagccaa gcagcagcaa gtggacatcc cccttcggct
      961 cctggtgccc acccagtatg tgggtgccat tattggcaag gagggggcca ccatccgcaa
     1021 catcacaaaa cagacccagt ccaagataga cgtgcatagg aaggagaacg caggtgcagc
     1081 tgaaaaagcc atcagtgtgc actccacccc tgagggctgc tcctccgctt gtaagatgat
     1141 cttggagatt atgcataaag aggctaagga caccaaaacg gctgacgagg ttcccctgaa
     1201 gatcctggcc cataataact ttgtagggcg tctcattggc aaggaaggac ggaacctgaa
     1261 gaaggtagag caagataccg agacaaaaat caccatctcc tcgttgcaag accttaccct
     1321 ttacaaccct gagaggacca tcactgtgaa gggggccatc gagaattgtt gcagggccga
     1381 gcaggaaata atgaagaaag ttcgggaggc ctatgagaat gatgtggctg ccatgagctc
     1441 tcacctgatc cctggcctga acctggctgc tgtaggtctt ttcccagctt catccagcgc
     1501 agtcccgccg cctcccagca gcgttactgg ggctgctccc tatagctcct ttatggctcc
     1561 cgagcaggag atggtgcagg tgtttatccc cgcccaggca gtgggcgcca tcatcggcaa
     1621 gaaggggcag cacatcaaac agctctcccg gtttgccagc gcctccatca agattgcacc
     1681 acccgaaaca cctgactcca aagttcgtat ggttatcatc actggaccgc cagaggccca
     1741 attcaaggct cagggaagaa tctatggcaa actcaaggag gagaacttct ttggtcccaa
     1801 ggaggaagtg aagctggaga cccacatacg tgtgccagca tcagcagctg gccgggtcat
     1861 tggcaaaggt ggaaaaacgg tgaacgagtt gcagaatttg acggcagctg aggtggtagt
     1921 accaagagac cagacccctg atgagaacga ccaggtcatc gtgaaaatca tcggacattt
     1981 ctatgccagt cagatggctc aacggaagat ccgagacatc ctggcccagg ttaagcagca
     2041 gcatcagaag ggacagagta accaggccca ggcacggagg aagtgaccag cccctccctg
     2101 tcccttcgag tccaggacaa caacgggcag aaatcgagag tgtgctctcc ccggcaggcc
     2161 tgagaatgag tgggaatccg ggacacctgg gccgggctgt agatcaggtt tgcccacttg
     2221 attgagaaag atgttccagt gaggaaccct gatctctcag ccccaaacac ccacccaatt
     2281 ggcccaacac tgtctgcccc tcggggtgtc agaaattcta gcgcaaggca cttttaaacg
     2341 tggattgttt aaagaagctc tccaggcccc accaagaggg tggatcacac ctcagtggga
     2401 agaaaaataa aatttccttc aggttttaaa aacatgcaga gaggtgtttt aatcagcctt
     2461 aaaggatggt tcatttcttg accttaatgt ttttccaatc ttcttccccc tacttgggta
     2521 attgattaaa atacctccat ttacggcctc tttctatatt tacactaatt tttttatctt
     2581 tattgctacc agaaaaaaat gcgaacgaat gcattgcttt gcttacagta ttgactcaag
     2641 ggaaaagaac tgtcagtatc tgtagattaa ttccaatcac tccctaacca ataggtacaa
     2701 tacggaatga agaagagggg aaaatgggga gaaagatggt taaaatacat aataatccac
     2761 gtttaaaagg agcgcacttg tggctgatct atgccagatc accatcttca aattggcaca
     2821 actgaaattt ccccactctg ttggggcttc cccaccacat tcatgtccct ctcccgtgta
     2881 ggtttcacat tatgtccagg tgcacatagg tggtattgaa tgctcagcag ggtaggggct
     2941 gaccactgtc cctgattccc atcgttctca ggcggatttt atattttttt aaagtctatt
     3001 ttaatgattg gatatgagca ctgggaaggg gacgctaact ccccttgata aagtctcggt
     3061 tccatggagg acttgagtgg ccccaaaggc tgccacggtg ccctcacccc agcccatgtg
     3121 ctcccataag ggctggttcc tagaggcagg ggttgtgggg cactcccagc cacggcactg
     3181 ttaccttggt ggtgggactt ggaacccaac cctgagctcc cgataaagct aaagtccatc
     3241 atctggcaaa ttcagtaaat tggagagtac ttgcttctgt ttgtatctga gaggaatttt
     3301 taactgacgg cttctgtctc catgaatcat tatcagcatg atgaaaggtg tgtctaaaaa
     3361 acaattcaga ataccagcag cattgtacag caaggggtaa ataagcttaa tttattaatt
     3421 taccaggctt aattaagatc ccatggagtg tttagccctt gtgggagaca gaagccatca
     3481 gttaaatgag gttaggcctc tcctcctaat atactgattg acaatgcata ttagccaggt
     3541 aatgcacttt agctaccctg gacaatgcta tcaagtgtgc tgggaaggga ggaaggcctc
     3601 tctacatatg gaaaagccca tgcgtggagt tcccctcctt tcaacattgc aacaacagta
     3661 acaacaagac aaccgcaaca tgtgggcgta gtcaggcaat gctgtgtgcg aagtaaacta
     3721 cctcaaggta tgaagttacc tcagcaatta ttttcctttt tgttcccccc aaccccatta
     3781 aaaaaatttt tttttgattt ttgttttttt gcagcttgct gatattttat ataaaaaaga
     3841 aaagcaaagc aaaagagaag ctgatagtct tgaatatttt atttttttaa tgaaaagaaa
     3901 aaacaagaaa gttatgtttc ataatttctt acaacatgag ccagtaaccc tttaggaact
     3961 ctctatggag aacaggcctg gtgggaaagg ctttgggggc tgccccctta ggaggaggct
     4021 agtgctaaga gggaaggccc aggtttgaga gagcccagag gggcagagcc cagagccttg
     4081 tttggccctg atctctgact tctagagccc cagctgctgg cggctgctgg aatatcctac
     4141 ctgataggat taaaaggcct agtggagctg ggggctctca gtggttaaac aatgcccaac
     4201 aaccaaccag ctggcccttg gtctcctctc tttcctcctt tggttaaaga gcatctcagc
     4261 cagcttttcc caccagtggt gctgttgaga tattttaaaa tattgcctcc gttttatcga
     4321 ggagagaaat aataactaaa aaatataccc tttaaaaaaa cctatatttc tctgtctaaa
     4381 aatatgggag ctgagattcc gttcgtggaa aaaagacaag gccaccctct cgccctcaga
     4441 gaggtccacc tggtttgtca ttgcaatgct tttcattttt tttttttgtt attgtttcat
     4501 ttcagttccg tcttgctatt cttcctaatc tatatccata gatctaaggg gcaaacagat
     4561 actagttaac tgcccccacc tctgtctccc tgtcttcttt agatcggtct gattgatttt
     4621 aaaagtggac ccaaacttag ggaattcttg atttagggtg gctggtggca aggaggggca
     4681 ggggatatgg ggacgtgact gggacaggtt cctgccttat cattttctcc ctaggacatt
     4741 cccttgtagc ccccagaatt gtctggccca aattgaatag aagcagaaaa acatttaggg
     4801 ataacatcag gccagtagaa ttaagcctct ccacctgtcc caaccataaa aagggtctcc
     4861 cagctttcca tctctggctc tatatgcttt atcccaaaac aaagcagata acgttcagac
     4921 gtcggccatt tagtaattta aagcgaattt ccagcagcaa gcatgctttg atatctggtt
     4981 cagactatca tcaggaagaa aaaaaaatcc cacagtacct gaaatgtgat tgttgcagtg
     5041 ttcagtttcc ttgggggcct gctcccttca caccttgagc ccaagtcctt ttccgttggc
     5101 tgattcagct cccagaagag acgaggaagt gtgtggcaag ggactggaaa acttcacttg
     5161 cttggattag gcaaggctcc actcattgtt gatatttgcc cagcaggaaa atcatgtaag
     5221 ttataccacc agaaagcaaa aggagcatgg tttggtggtt aaggtttagt gggatgaagg
     5281 acctgtcttg gtgggccggg ccctcttgtg ccccgtaggc taggtcttag ggcaactcct
     5341 tgccctcctg ctcagcacct ccatttcccc atccttggtg agataacaag ctatcgcgaa
     5401 aagcacttgg gagatttgga tgatttgaga agagtgactt aaaaaaaatg cttctgtgct
     5461 ctaagatata tatgtgtgtg tgtgtgctac atatatattt ttaagaaagg accatctctt
     5521 taggatatat ttttaaattc tttgaaacac ataaccaaaa tggtttgatt cactgactga
     5581 ctttgaagct gcatctgcca gttacacccc aaatggcttt aatcccctct cgggtctggt
     5641 tgccttttgc agtttgggtt gtggactcag ctcctgtgag gggtctggtt aggagagagc
     5701 catttttaag gacagggagt tttatagccc ttttctactt tcctcccctc ctcccagtcc
     5761 ttatcaatct tttttccttt ttcctgaccc cctccttctg gaggcagttg ggagctatcc
     5821 ttgtttatgc ctcactattg gcagaaaaga ccccatttaa aacccagaga acactggagg
     5881 gggatgctct agttggttct gtgtccattt tcctctgtgc caaagacaga cagacagagg
     5941 ctgagagagg ctgttcctga atcaaagcaa tagccagctt tcgacacata cctggctgtc
     6001 tgaggaggaa ggcctcctgg aaactgggag ctaagggcga ggcccttccc ttcagaggct
     6061 cctgggggat tagggtgtgg tgtttgccaa gccaaggggt agggagccga gaaattggtc
     6121 tgtcggctcc tggttgcact ttggggaagg agaggaagtt tggggctcca ggtagctccc
     6181 tgttgtggga ctgctctgtc ccctgcccct actgcagaga tagcactgcc gagttccctt
     6241 caggcctggc agacgggcag tgaggagggg cctcagttag ctctcaaggg tgccttcccc
     6301 tcctcccaac ccagacatac cctctgccaa actgggaacc agcagtgcta gtaactacct
     6361 cacagagccc cagagggcct gcttgagcct tcttgctcca caggagaagc tggtgcctct
     6421 aggcaacccc ttcctcccac ctctcatcag gggtgggggt tctcctttct ttcccctgaa
     6481 gtgtttatgg ggagatccta gtggctttgc cattcaaacc actcgactgt ttgcctgttt
     6541 cttgaaaacc agtagaaggg aaacagcaca gcctgtcaca gtaattgcag gaagattgaa
     6601 gaaaaatcct catcaatgcc aggggacata aaagccattt cccttccaaa tactcgacaa
     6661 tttagatgca gaacatttct ctgtattcag acttagagta acaccagctg aaaactgcag
     6721 tttctttcct ttggatacat aaggcttctc tatcggggta cgggacaggg aggaggcctc
     6781 atgtctgaag ggggatttag gggcgagagc cccagccctg accctcggtc ctgtgcaccg
     6841 ctttggggca cagtctgatg gcgcctttgc tggcgcctta gtatggttga ctccggatgg
     6901 acaaaagaaa aaaaattttt tttcttgaat gaaatagcag gaagctcctc gggagcatgt
     6961 gttttgatta accgcaggtg atggatgcta cgagtataaa tggattaact acctcaatcc
     7021 ttacagtaag attggaacta agggcaggga ctcatgcata agggtatgaa tcccagccag
     7081 gacaagtgag ttgaggcttg tgccacaaaa ggtttgtcct tggggaacag gcaggcctgc
     7141 caggatcccc cccatatcga ttgggctggg agggctggcc atgaggtccc cactttctgc
     7201 tttccttgcc catgtgtcac ccctttggcc tccagcttgt ccctctctca ctttctatag
     7261 ctttgttgga ccagatggtg aggaaaggaa tggcctcttc ccttctagag ggggctggct
     7321 ggagtgagac ctggggcttg gcctggaacc caccacacag ccccaaagtc aggaagcctg
     7381 gggaaaccag agctgagacc tcttcaacag ggtttctttg agatcctaca cctccattgg
     7441 gccctttttc agtcttcaat gggggcccag ttggctctag aaggagaaga ggtgaagcag
     7501 gatcctttgc cctgggggag tctgagggcg cggtccttgg actcattcag gccgtctttg
     7561 tagttggggg agttccactg ggcgatccca gcccctcccc acccaccctc taatggacct
     7621 cctcatagaa gccccatttc acttttgttt tatctacctc ttagcaaaac aatagataaa
     7681 ttaggtagtg gcagctccac ttgcttaggt taggggggga aaaagatttc tttttccaaa
     7741 ggaaaaaaat attaccttga gaatactttc caaaaaataa aattaaaaaa aaaaaaacca
     7801 aaaaaaaaaa ttttttttta aaagggagac attttccagt gaccactgga ttgttttaat
     7861 ttcccaagct tttttttccc ccataaataa gtttcactct ttggcgattt tcttcacttg
     7921 tttaagataa cgtgctagct attccaacag gtaacagctt tcacagtctg cccctggcct
     7981 gtctcacccc atcccccacc ctattcctgc cagtgagtcc ttcctgtgct tctctccctt
     8041 ctcccctccc agccagctga cttcagtcac ccctgtcccc cctcccctgc caataagctc
     8101 ccccaggaat aaaggctttg ttttggggat gcttaaatct tgactggcac ttcccggctg
     8161 tgggggctgg ggagccactt gtaacatttc tgtgcagatt ttatgttagc cactgctatg
     8221 taaaagcacg ttcaaaatga atttcagcag attatgtgtt accataatga ataaacgtcc
     8281 tctatcacca tttggagtct cccttttctc caggatcttg atcctggtcc ccaaaaccag
     8341 agtgaatcaa aagagcttcc tcccctgagg caaagtggat ttgtaagcag ttctgaaaca
     8401 tcacttactc agaagaggga acgatgtatt ttgatgagtg caaattggga agagctggag
     8461 gcctactgct tgggacagtt tttttttttt tttttttttt aaatatgagt gctagcttat
     8521 tctgtaattg cggcaacttt gaaaattgta ttttactgga aatctgccag ccatcaccac
     8581 ccgattttga ttgtatcctt cctcccatcc tttaatctgt tcattgcttt gggggaggtg
     8641 gggcagctgg ctcacacgtt ggagtttgtt ctttgatgga tgaacgaaca ctccagtttt
     8701 ctttcccgtg aaggttgttt cagccacaaa ccacttcatt ttgctgtttc aatttcaaaa
     8761 taaaaggaaa cttatattga aagacaa
//
