LOCUS       XM_017024022            8790 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens insulin like growth factor 2 mRNA binding
            protein 1 (IGF2BP1), transcript variant X3, mRNA.
ACCESSION   XM_017024022
VERSION     XM_017024022.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017024022.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8790
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..8790
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /note="insulin like growth factor 2 mRNA binding protein
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 11 ESTs, 1994 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 10 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
     CDS             362..2089
                     /gene="IGF2BP1"
                     /gene_synonym="CRD-BP; CRDBP; IMP-1; IMP1; VICKZ1; ZBP1"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 1 isoform X3"
                     /protein_id="XP_016879511.1"
                     /db_xref="GeneID:10642"
                     /db_xref="HGNC:HGNC:28866"
                     /db_xref="MIM:608288"
                     /translation="MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDC
                     PDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLA
                     QYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIA
                     QGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATI
                     RNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADE
                     VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE
                     NCCRAEQEIMKKVREAYENDVAAMSSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAA
                     PYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVR
                     MVIITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTV
                     NELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQ
                     SNQAQARRK"
ORIGIN      
        1 cgctccattt tttttcaagt cgattttatt tagaggcggc gccagggcgg ccgcggagaa
       61 acgtgacaca ccagccctct cggaggggtt tcggaccgaa gggaagaagc tgcgccgtgt
      121 cgtccgtctc cctgcgcgcc gcgggcactt ctcctgggct ctccccgaac tctcccgcga
      181 cctctgcgcg ccctcaggcc gccttccccg ccctgggctc gggacaactt ctggggtggg
      241 gtgcaaagaa agtttgcggc tcctgccgcc ggcctctccg cctcttggcc taggaggctc
      301 gccgcccgcg cccgctcgtt cggccttgcc cgggaccgcg tcctgccccg agaccgccac
      361 catgaacaag ctttacatcg gcaacctcaa cgagagcgtg acccccgcgg acttggagaa
      421 agtgtttgcg gagcacaaga tctcctacag cggccagttc ttggtcaaat ccggctacgc
      481 cttcgtggac tgcccggacg agcactgggc gatgaaggcc atcgaaactt tctccgggaa
      541 agtagaatta caaggaaaac gcttagagat tgaacattcg gtgcccaaaa aacaaaggag
      601 ccggaaaatt caaatccgaa atattccacc ccagctccga tgggaagtac tggacagcct
      661 gctggctcag tatggtacag tagagaactg tgagcaagtg aacaccgaga gtgagacggc
      721 agtggtgaat gtcacctatt ccaaccggga gcagaccagg caagccatca tgaagctgaa
      781 tggccaccag ttggagaacc atgccctgaa ggtctcctac atccccgatg agcagatagc
      841 acagggacct gagaatgggc gccgaggggg ctttggctct cggggtcagc cccgccaggg
      901 ctcacctgtg gcagcggggg ccccagccaa gcagcagcaa gtggacatcc cccttcggct
      961 cctggtgccc acccagtatg tgggtgccat tattggcaag gagggggcca ccatccgcaa
     1021 catcacaaaa cagacccagt ccaagataga cgtgcatagg aaggagaacg caggtgcagc
     1081 tgaaaaagcc atcagtgtgc actccacccc tgagggctgc tcctccgctt gtaagatgat
     1141 cttggagatt atgcataaag aggctaagga caccaaaacg gctgacgagg ttcccctgaa
     1201 gatcctggcc cataataact ttgtagggcg tctcattggc aaggaaggac ggaacctgaa
     1261 gaaggtagag caagataccg agacaaaaat caccatctcc tcgttgcaag accttaccct
     1321 ttacaaccct gagaggacca tcactgtgaa gggggccatc gagaattgtt gcagggccga
     1381 gcaggaaata atgaagaaag ttcgggaggc ctatgagaat gatgtggctg ccatgagctc
     1441 tcacctgatc cctggcctga acctggctgc tgtaggtctt ttcccagctt catccagcgc
     1501 agtcccgccg cctcccagca gcgttactgg ggctgctccc tatagctcct ttatgcaggc
     1561 tcccgagcag gagatggtgc aggtgtttat ccccgcccag gcagtgggcg ccatcatcgg
     1621 caagaagggg cagcacatca aacagctctc ccggtttgcc agcgcctcca tcaagattgc
     1681 accacccgaa acacctgact ccaaagttcg tatggttatc atcactggac cgccagaggc
     1741 ccaattcaag gctcagggaa gaatctatgg caaactcaag gaggagaact tctttggtcc
     1801 caaggaggaa gtgaagctgg agacccacat acgtgtgcca gcatcagcag ctggccgggt
     1861 cattggcaaa ggtggaaaaa cggtgaacga gttgcagaat ttgacggcag ctgaggtggt
     1921 agtaccaaga gaccagaccc ctgatgagaa cgaccaggtc atcgtgaaaa tcatcggaca
     1981 tttctatgcc agtcagatgg ctcaacggaa gatccgagac atcctggccc aggttaagca
     2041 gcagcatcag aagggacaga gtaaccaggc ccaggcacgg aggaagtgac cagcccctcc
     2101 ctgtcccttc gagtccagga caacaacggg cagaaatcga gagtgtgctc tccccggcag
     2161 gcctgagaat gagtgggaat ccgggacacc tgggccgggc tgtagatcag gtttgcccac
     2221 ttgattgaga aagatgttcc agtgaggaac cctgatctct cagccccaaa cacccaccca
     2281 attggcccaa cactgtctgc ccctcggggt gtcagaaatt ctagcgcaag gcacttttaa
     2341 acgtggattg tttaaagaag ctctccaggc cccaccaaga gggtggatca cacctcagtg
     2401 ggaagaaaaa taaaatttcc ttcaggtttt aaaaacatgc agagaggtgt tttaatcagc
     2461 cttaaaggat ggttcatttc ttgaccttaa tgtttttcca atcttcttcc ccctacttgg
     2521 gtaattgatt aaaatacctc catttacggc ctctttctat atttacacta atttttttat
     2581 ctttattgct accagaaaaa aatgcgaacg aatgcattgc tttgcttaca gtattgactc
     2641 aagggaaaag aactgtcagt atctgtagat taattccaat cactccctaa ccaataggta
     2701 caatacggaa tgaagaagag gggaaaatgg ggagaaagat ggttaaaata cataataatc
     2761 cacgtttaaa aggagcgcac ttgtggctga tctatgccag atcaccatct tcaaattggc
     2821 acaactgaaa tttccccact ctgttggggc ttccccacca cattcatgtc cctctcccgt
     2881 gtaggtttca cattatgtcc aggtgcacat aggtggtatt gaatgctcag cagggtaggg
     2941 gctgaccact gtccctgatt cccatcgttc tcaggcggat tttatatttt tttaaagtct
     3001 attttaatga ttggatatga gcactgggaa ggggacgcta actccccttg ataaagtctc
     3061 ggttccatgg aggacttgag tggccccaaa ggctgccacg gtgccctcac cccagcccat
     3121 gtgctcccat aagggctggt tcctagaggc aggggttgtg gggcactccc agccacggca
     3181 ctgttacctt ggtggtggga cttggaaccc aaccctgagc tcccgataaa gctaaagtcc
     3241 atcatctggc aaattcagta aattggagag tacttgcttc tgtttgtatc tgagaggaat
     3301 ttttaactga cggcttctgt ctccatgaat cattatcagc atgatgaaag gtgtgtctaa
     3361 aaaacaattc agaataccag cagcattgta cagcaagggg taaataagct taatttatta
     3421 atttaccagg cttaattaag atcccatgga gtgtttagcc cttgtgggag acagaagcca
     3481 tcagttaaat gaggttaggc ctctcctcct aatatactga ttgacaatgc atattagcca
     3541 ggtaatgcac tttagctacc ctggacaatg ctatcaagtg tgctgggaag ggaggaaggc
     3601 ctctctacat atggaaaagc ccatgcgtgg agttcccctc ctttcaacat tgcaacaaca
     3661 gtaacaacaa gacaaccgca acatgtgggc gtagtcaggc aatgctgtgt gcgaagtaaa
     3721 ctacctcaag gtatgaagtt acctcagcaa ttattttcct ttttgttccc cccaacccca
     3781 ttaaaaaaat ttttttttga tttttgtttt tttgcagctt gctgatattt tatataaaaa
     3841 agaaaagcaa agcaaaagag aagctgatag tcttgaatat tttatttttt taatgaaaag
     3901 aaaaaacaag aaagttatgt ttcataattt cttacaacat gagccagtaa ccctttagga
     3961 actctctatg gagaacaggc ctggtgggaa aggctttggg ggctgccccc ttaggaggag
     4021 gctagtgcta agagggaagg cccaggtttg agagagccca gaggggcaga gcccagagcc
     4081 ttgtttggcc ctgatctctg acttctagag ccccagctgc tggcggctgc tggaatatcc
     4141 tacctgatag gattaaaagg cctagtggag ctgggggctc tcagtggtta aacaatgccc
     4201 aacaaccaac cagctggccc ttggtctcct ctctttcctc ctttggttaa agagcatctc
     4261 agccagcttt tcccaccagt ggtgctgttg agatatttta aaatattgcc tccgttttat
     4321 cgaggagaga aataataact aaaaaatata ccctttaaaa aaacctatat ttctctgtct
     4381 aaaaatatgg gagctgagat tccgttcgtg gaaaaaagac aaggccaccc tctcgccctc
     4441 agagaggtcc acctggtttg tcattgcaat gcttttcatt tttttttttt gttattgttt
     4501 catttcagtt ccgtcttgct attcttccta atctatatcc atagatctaa ggggcaaaca
     4561 gatactagtt aactgccccc acctctgtct ccctgtcttc tttagatcgg tctgattgat
     4621 tttaaaagtg gacccaaact tagggaattc ttgatttagg gtggctggtg gcaaggaggg
     4681 gcaggggata tggggacgtg actgggacag gttcctgcct tatcattttc tccctaggac
     4741 attcccttgt agcccccaga attgtctggc ccaaattgaa tagaagcaga aaaacattta
     4801 gggataacat caggccagta gaattaagcc tctccacctg tcccaaccat aaaaagggtc
     4861 tcccagcttt ccatctctgg ctctatatgc tttatcccaa aacaaagcag ataacgttca
     4921 gacgtcggcc atttagtaat ttaaagcgaa tttccagcag caagcatgct ttgatatctg
     4981 gttcagacta tcatcaggaa gaaaaaaaaa tcccacagta cctgaaatgt gattgttgca
     5041 gtgttcagtt tccttggggg cctgctccct tcacaccttg agcccaagtc cttttccgtt
     5101 ggctgattca gctcccagaa gagacgagga agtgtgtggc aagggactgg aaaacttcac
     5161 ttgcttggat taggcaaggc tccactcatt gttgatattt gcccagcagg aaaatcatgt
     5221 aagttatacc accagaaagc aaaaggagca tggtttggtg gttaaggttt agtgggatga
     5281 aggacctgtc ttggtgggcc gggccctctt gtgccccgta ggctaggtct tagggcaact
     5341 ccttgccctc ctgctcagca cctccatttc cccatccttg gtgagataac aagctatcgc
     5401 gaaaagcact tgggagattt ggatgatttg agaagagtga cttaaaaaaa atgcttctgt
     5461 gctctaagat atatatgtgt gtgtgtgtgc tacatatata tttttaagaa aggaccatct
     5521 ctttaggata tatttttaaa ttctttgaaa cacataacca aaatggtttg attcactgac
     5581 tgactttgaa gctgcatctg ccagttacac cccaaatggc tttaatcccc tctcgggtct
     5641 ggttgccttt tgcagtttgg gttgtggact cagctcctgt gaggggtctg gttaggagag
     5701 agccattttt aaggacaggg agttttatag cccttttcta ctttcctccc ctcctcccag
     5761 tccttatcaa tcttttttcc tttttcctga ccccctcctt ctggaggcag ttgggagcta
     5821 tccttgttta tgcctcacta ttggcagaaa agaccccatt taaaacccag agaacactgg
     5881 agggggatgc tctagttggt tctgtgtcca ttttcctctg tgccaaagac agacagacag
     5941 aggctgagag aggctgttcc tgaatcaaag caatagccag ctttcgacac atacctggct
     6001 gtctgaggag gaaggcctcc tggaaactgg gagctaaggg cgaggccctt cccttcagag
     6061 gctcctgggg gattagggtg tggtgtttgc caagccaagg ggtagggagc cgagaaattg
     6121 gtctgtcggc tcctggttgc actttgggga aggagaggaa gtttggggct ccaggtagct
     6181 ccctgttgtg ggactgctct gtcccctgcc cctactgcag agatagcact gccgagttcc
     6241 cttcaggcct ggcagacggg cagtgaggag gggcctcagt tagctctcaa gggtgccttc
     6301 ccctcctccc aacccagaca taccctctgc caaactggga accagcagtg ctagtaacta
     6361 cctcacagag ccccagaggg cctgcttgag ccttcttgct ccacaggaga agctggtgcc
     6421 tctaggcaac cccttcctcc cacctctcat caggggtggg ggttctcctt tctttcccct
     6481 gaagtgttta tggggagatc ctagtggctt tgccattcaa accactcgac tgtttgcctg
     6541 tttcttgaaa accagtagaa gggaaacagc acagcctgtc acagtaattg caggaagatt
     6601 gaagaaaaat cctcatcaat gccaggggac ataaaagcca tttcccttcc aaatactcga
     6661 caatttagat gcagaacatt tctctgtatt cagacttaga gtaacaccag ctgaaaactg
     6721 cagtttcttt cctttggata cataaggctt ctctatcggg gtacgggaca gggaggaggc
     6781 ctcatgtctg aagggggatt taggggcgag agccccagcc ctgaccctcg gtcctgtgca
     6841 ccgctttggg gcacagtctg atggcgcctt tgctggcgcc ttagtatggt tgactccgga
     6901 tggacaaaag aaaaaaaatt ttttttcttg aatgaaatag caggaagctc ctcgggagca
     6961 tgtgttttga ttaaccgcag gtgatggatg ctacgagtat aaatggatta actacctcaa
     7021 tccttacagt aagattggaa ctaagggcag ggactcatgc ataagggtat gaatcccagc
     7081 caggacaagt gagttgaggc ttgtgccaca aaaggtttgt ccttggggaa caggcaggcc
     7141 tgccaggatc ccccccatat cgattgggct gggagggctg gccatgaggt ccccactttc
     7201 tgctttcctt gcccatgtgt cacccctttg gcctccagct tgtccctctc tcactttcta
     7261 tagctttgtt ggaccagatg gtgaggaaag gaatggcctc ttcccttcta gagggggctg
     7321 gctggagtga gacctggggc ttggcctgga acccaccaca cagccccaaa gtcaggaagc
     7381 ctggggaaac cagagctgag acctcttcaa cagggtttct ttgagatcct acacctccat
     7441 tgggcccttt ttcagtcttc aatgggggcc cagttggctc tagaaggaga agaggtgaag
     7501 caggatcctt tgccctgggg gagtctgagg gcgcggtcct tggactcatt caggccgtct
     7561 ttgtagttgg gggagttcca ctgggcgatc ccagcccctc cccacccacc ctctaatgga
     7621 cctcctcata gaagccccat ttcacttttg ttttatctac ctcttagcaa aacaatagat
     7681 aaattaggta gtggcagctc cacttgctta ggttaggggg ggaaaaagat ttctttttcc
     7741 aaaggaaaaa aatattacct tgagaatact ttccaaaaaa taaaattaaa aaaaaaaaaa
     7801 ccaaaaaaaa aaattttttt ttaaaaggga gacattttcc agtgaccact ggattgtttt
     7861 aatttcccaa gctttttttt cccccataaa taagtttcac tctttggcga ttttcttcac
     7921 ttgtttaaga taacgtgcta gctattccaa caggtaacag ctttcacagt ctgcccctgg
     7981 cctgtctcac cccatccccc accctattcc tgccagtgag tccttcctgt gcttctctcc
     8041 cttctcccct cccagccagc tgacttcagt cacccctgtc ccccctcccc tgccaataag
     8101 ctcccccagg aataaaggct ttgttttggg gatgcttaaa tcttgactgg cacttcccgg
     8161 ctgtgggggc tggggagcca cttgtaacat ttctgtgcag attttatgtt agccactgct
     8221 atgtaaaagc acgttcaaaa tgaatttcag cagattatgt gttaccataa tgaataaacg
     8281 tcctctatca ccatttggag tctccctttt ctccaggatc ttgatcctgg tccccaaaac
     8341 cagagtgaat caaaagagct tcctcccctg aggcaaagtg gatttgtaag cagttctgaa
     8401 acatcactta ctcagaagag ggaacgatgt attttgatga gtgcaaattg ggaagagctg
     8461 gaggcctact gcttgggaca gttttttttt tttttttttt tttaaatatg agtgctagct
     8521 tattctgtaa ttgcggcaac tttgaaaatt gtattttact ggaaatctgc cagccatcac
     8581 cacccgattt tgattgtatc cttcctccca tcctttaatc tgttcattgc tttgggggag
     8641 gtggggcagc tggctcacac gttggagttt gttctttgat ggatgaacga acactccagt
     8701 tttctttccc gtgaaggttg tttcagccac aaaccacttc attttgctgt ttcaatttca
     8761 aaataaaagg aaacttatat tgaaagacaa
//
