LOCUS       NM_015662               5395 bp    mRNA    linear   PRI 07-FEB-2025
DEFINITION  Homo sapiens intraflagellar transport 172 (IFT172), transcript
            variant 1, mRNA.
ACCESSION   NM_015662
VERSION     NM_015662.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5395)
  AUTHORS   Neroldova,M., Ciara,E., Slatinska,J., Frankova,S., Liskova,P.,
            Kotalova,R., Globinovska,J., Safarikova,M., Pfeiferova,L.,
            Zunova,H., Mrazova,L., Stranecky,V., Vrbacka,A., Fabian,O.,
            Sticova,E., Skanderova,D., Sperl,J., Kalousova,M., Zima,T.,
            Macek,M., Pawlowska,J., Knisely,A.S., Kmoch,S. and Jirsa,M.
  TITLE     Exome sequencing reveals IFT172 variants in patients with
            non-syndromic cholestatic liver disease
  JOURNAL   PLoS One 18 (7), e0288907 (2023)
   PUBMED   37471416
  REMARK    GeneRIF: Exome sequencing reveals IFT172 variants in patients with
            non-syndromic cholestatic liver disease.
            Erratum:[PLoS One. 2025 Jan 30;20(1):e0318705. doi:
            10.1371/journal.pone.0318705.. PMID: 39883651]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5395)
  AUTHORS   Onodera,S., Morita,N., Nakamura,Y., Takahashi,S., Hashimoto,K.,
            Nomura,T., Katakura,A., Kosaki,K. and Azuma,T.
  TITLE     Novel alterations in IFT172 and KIFAP3 may induce basal cell
            carcinoma
  JOURNAL   Orphanet J Rare Dis 16 (1), 443 (2021)
   PUBMED   34674729
  REMARK    GeneRIF: Novel alterations in IFT172 and KIFAP3 may induce basal
            cell carcinoma.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5395)
  AUTHORS   Romano,F., Dautaj,A., Esposito,R.A., Bertelli,M., Staurenghi,G. and
            Salvetti,A.P.
  TITLE     Multimodal imaging of retinitis pigmentosa associated with
            Mainzer-Saldino syndrome
  JOURNAL   Ophthalmic Genet 42 (2), 218-221 (2021)
   PUBMED   33393400
  REMARK    GeneRIF: Multimodal imaging of retinitis pigmentosa associated with
            Mainzer-Saldino syndrome.
REFERENCE   4  (bases 1 to 5395)
  AUTHORS   O'Seaghdha,C.M., Yang,Q., Glazer,N.L., Leak,T.S., Dehghan,A.,
            Smith,A.V., Kao,W.H., Lohman,K., Hwang,S.J., Johnson,A.D.,
            Hofman,A., Uitterlinden,A.G., Chen,Y.D., Brown,E.M.,
            Siscovick,D.S., Harris,T.B., Psaty,B.M., Coresh,J., Gudnason,V.,
            Witteman,J.C., Liu,Y.M., Kestenbaum,B.R., Fox,C.S. and Kottgen,A.
  CONSRTM   GEFOS Consortium
  TITLE     Common variants in the calcium-sensing receptor gene are associated
            with total serum calcium levels
  JOURNAL   Hum Mol Genet 19 (21), 4296-4303 (2010)
   PUBMED   20705733
REFERENCE   5  (bases 1 to 5395)
  AUTHORS   Kottgen,A., Pattaro,C., Boger,C.A., Fuchsberger,C., Olden,M.,
            Glazer,N.L., Parsa,A., Gao,X., Yang,Q., Smith,A.V., O'Connell,J.R.,
            Li,M., Schmidt,H., Tanaka,T., Isaacs,A., Ketkar,S., Hwang,S.J.,
            Johnson,A.D., Dehghan,A., Teumer,A., Pare,G., Atkinson,E.J.,
            Zeller,T., Lohman,K., Cornelis,M.C., Probst-Hensch,N.M.,
            Kronenberg,F., Tonjes,A., Hayward,C., Aspelund,T., Eiriksdottir,G.,
            Launer,L.J., Harris,T.B., Rampersaud,E., Mitchell,B.D.,
            Arking,D.E., Boerwinkle,E., Struchalin,M., Cavalieri,M.,
            Singleton,A., Giallauria,F., Metter,J., de Boer,I.H.,
            Haritunians,T., Lumley,T., Siscovick,D., Psaty,B.M.,
            Zillikens,M.C., Oostra,B.A., Feitosa,M., Province,M., de
            Andrade,M., Turner,S.T., Schillert,A., Ziegler,A., Wild,P.S.,
            Schnabel,R.B., Wilde,S., Munzel,T.F., Leak,T.S., Illig,T.,
            Klopp,N., Meisinger,C., Wichmann,H.E., Koenig,W., Zgaga,L.,
            Zemunik,T., Kolcic,I., Minelli,C., Hu,F.B., Johansson,A., Igl,W.,
            Zaboli,G., Wild,S.H., Wright,A.F., Campbell,H., Ellinghaus,D.,
            Schreiber,S., Aulchenko,Y.S., Felix,J.F., Rivadeneira,F.,
            Uitterlinden,A.G., Hofman,A., Imboden,M., Nitsch,D.,
            Brandstatter,A., Kollerits,B., Kedenko,L., Magi,R., Stumvoll,M.,
            Kovacs,P., Boban,M., Campbell,S., Endlich,K., Volzke,H.,
            Kroemer,H.K., Nauck,M., Volker,U., Polasek,O., Vitart,V.,
            Badola,S., Parker,A.N., Ridker,P.M., Kardia,S.L., Blankenberg,S.,
            Liu,Y., Curhan,G.C., Franke,A., Rochat,T., Paulweber,B.,
            Prokopenko,I., Wang,W., Gudnason,V., Shuldiner,A.R., Coresh,J.,
            Schmidt,R., Ferrucci,L., Shlipak,M.G., van Duijn,C.M., Borecki,I.,
            Kramer,B.K., Rudan,I., Gyllensten,U., Wilson,J.F., Witteman,J.C.,
            Pramstaller,P.P., Rettig,R., Hastie,N., Chasman,D.I., Kao,W.H.,
            Heid,I.M. and Fox,C.S.
  TITLE     New loci associated with kidney function and chronic kidney disease
  JOURNAL   Nat Genet 42 (5), 376-384 (2010)
   PUBMED   20383146
REFERENCE   6  (bases 1 to 5395)
  AUTHORS   Howard,P.W. and Maurer,R.A.
  TITLE     Identification of a conserved protein that interacts with specific
            LIM homeodomain transcription factors
  JOURNAL   J Biol Chem 275 (18), 13336-13342 (2000)
   PUBMED   10788441
REFERENCE   7  (bases 1 to 5395)
  AUTHORS   Stokman,M., Lilien,M. and Knoers,N.
  TITLE     Nephronophthisis-Related Ciliopathies
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   27336129
REFERENCE   8  (bases 1 to 5395)
  AUTHORS   Fahim,A.T., Daiger,S.P. and Weleber,R.G.
  TITLE     Nonsyndromic Retinitis Pigmentosa Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301590
REFERENCE   9  (bases 1 to 5395)
  AUTHORS   Forsyth,R. and Gunay-Aygun,M.
  TITLE     Bardet-Biedl Syndrome Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301537
REFERENCE   10 (bases 1 to 5395)
  AUTHORS   Parisi,M. and Glass,I.
  TITLE     Joubert Syndrome
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE and
            Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   20301500
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC394416.1, BC137126.1 and
            BC047294.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_015662.2.
            
            Summary: This gene encodes a subunit of the intraflagellar
            transport subcomplex IFT-B. Subcomplexes IFT-A and IFT-B are
            necessary for ciliary assembly and maintenance. Mutations in this
            gene have been associated with skeletal ciliopathies, with or
            without polydactyly, such as such short-rib thoracic dysplasias 1,
            9 or 10. [provided by RefSeq, Mar 2014].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660805.134858.1,
                                           SRR1803617.133332.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000260570.8/ ENSP00000260570.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                DC394416.1         69-110
            43-5374             BC137126.1         1-5332
            5375-5395           BC047294.1         1740-1760
FEATURES             Location/Qualifiers
     source          1..5395
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2p23.3"
     gene            1..5395
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /note="intraflagellar transport 172"
                     /db_xref="GeneID:26160"
                     /db_xref="HGNC:HGNC:30391"
                     /db_xref="MIM:607386"
     exon            1..129
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..5340
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /note="isoform 1 is encoded by transcript variant 1;
                     wimple homolog; selective LIM binding factor homolog;
                     intraflagellar transport protein 172 homolog;
                     intraflagellar transport 172 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 172 homolog
                     isoform 1"
                     /protein_id="NP_056477.1"
                     /db_xref="CCDS:CCDS1755.1"
                     /db_xref="GeneID:26160"
                     /db_xref="HGNC:HGNC:30391"
                     /db_xref="MIM:607386"
                     /translation="MHLKHLRTLLSPQDGAAKVTCMAWSQNNAKFAVCTVDRVVLLYD
                     EHGERRDKFSTKPADMKYGRKSYMVKGMAFSPDSTKIAIGQTDNIIYVYKIGEDWGDK
                     KVICNKFIQTSAVTCLQWPAEYIIVFGLAEGKVRLANTKTNKSSTIYGTESYVVSLTT
                     NCSGKGILSGHADGTIVRYFFDDEGSGESQGKLVNHPCPPYALAWATNSIVAAGCDRK
                     IVAYGKEGHMLQTFDYSRDPQEREFTTAVSSPGGQSVVLGSYDRLRVFNWIPRRSIWE
                     EAKPKEITNLYTITALAWKRDGSRLCVGTLCGGVEQFDCCLRRSIYKNKFELTYVGPS
                     QVIVKNLSSGTRVVLKSHYGYEVEEVKILGKERYLVAHTSETLLLGDLNTNRLSEIAW
                     QGSGGNEKYFFENENVCMIFNAGELTLVEYGNNDTLGSVRTEFMNPHLISVRINERCQ
                     RGTEDNKKLAYLIDIKTIAIVDLIGGYNIGTVSHESRVDWLELNETGHKLLFRDRKLR
                     LHLYDIESCSKTMILNFCSYMQWVPGSDVLVAQNRNSLCVWYNIEAPERVTMFTIRGD
                     VIGLERGGGKTEVMVMEGVTTVAYTLDEGLIEFGTAIDDGNYIRATAFLETLEMTPET
                     EAMWKTLSKLALEARQLHIAERCFSALGQVAKARFLHETNEIADQVSREYGGEGTDFY
                     QVRARLAMLEKNYKLAEMIFLEQNAVEEAMGMYQELHRWDECIAVAEAKGHPALEKLR
                     RSYYQWLMDTQQEERAGELQESQGDGLAAISLYLKAGLPAKAARLVLTREELLANTEL
                     VEHITAALIKGELYERAGDLFEKIHNPQKALECYRKGNAFMKAVELARLAFPVEVVKL
                     EEAWGDHLVQQKQLDAAINHYIEARCSIKAIEAALGARQWKKAIYILDLQDRNTASKY
                     YPLVAQHYASLQEYEIAEELYTKGDRTKDAIDMYTQAGRWEQAHKLAMKCMRPEDVSV
                     LYITQAQEMEKQGKYREAERLYVTVQEPDLAITMYKKHKLYDDMIRLVGKHHPDLLSD
                     THLHLGKELEAEGRLQEAEYHYLEAQEWKATVNMYRASGLWEEAYRVARTQGGANAHK
                     HVAYLWAKSLGGEAAVRLLNKLGLLEAAVDHAADNCSFEFAFELSRLALKHKTPEVHL
                     KYAMFLEDEGKFEEAEAEFIRAGKPKEAVLMFVHNQDWEAAQRVAEAHDPDSVAEVLV
                     GQARGALEEKDFQKAEGLLLRAQRPGLALNYYKEAGLWSDALRICKDYVPSQLEALQE
                     EYEREATKKGARGVEGFVEQARHWEQAGEYSRAVDCYLKVRDSGNSGLAEKCWMKAAE
                     LSIKFLPPQRNMEVVLAVGPQLIGIGKHSAAAELYLNLDLVKEAIDAFIEGEEWNKAK
                     RVAKELDPRYEDYVDQHYKEFLKNQGKVDSLVGVDVIAALDLYVEQGQWDKCIETATK
                     QNYKILHKYVALYATHLIREGSSAQALALYVQHGAPANPQNFNIYKRIFTDMVSSPGT
                     NCAEAYHSWADLRDVLFNLCENLVKSSEANSPAHEEFKTMLLIAHYYATRSAAQSVKQ
                     LETVAARLSVSLLRHTQLLPVDKAFYEAGIAAKAVGWDNMAFIFLNRFLDLTDAIEEG
                     TLDGLDHSDFQDTDIPFEVPLPAKQHVPEAEREEVRDWVLTVSMDQRLEQVLPRDERG
                     AYEASLVAASTGVRALPCLITGYPILRNKIEFKRPGKAANKDNWNKFLMAIKTSHSPV
                     CQDVLKFISQWCGGLPSTSFSFQ"
     exon            130..273
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            274..386
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            387..426
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            427..492
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            493..572
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            573..660
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            661..875
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            876..999
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1095
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1257
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1311
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..1415
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1416..1501
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1614
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1782
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1919
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            1920..2027
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2028..2112
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2113..2205
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2206..2283
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2532
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2533..2611
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2732
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2733..2877
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2878..2967
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            2968..3065
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3066..3201
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3202..3318
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3319..3461
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3462..3555
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3556..3620
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3621..3801
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3802..3911
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            3912..4041
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4042..4140
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4141..4250
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4251..4314
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4315..4401
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4402..4518
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4519..4629
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4630..4749
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4750..4845
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4846..4905
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            4906..5004
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            5005..5158
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            5159..5250
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     exon            5251..5395
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5377..5382
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /note="hexamer: ATTAAA"
     polyA_site      5395
                     /gene="IFT172"
                     /gene_synonym="BBS20; NPHP17; osm-1; RP71; SLB; SRTD10;
                     wim"
                     /note="major polyA site"
ORIGIN      
        1 agtgcctgtc gctgcggctg cgtggcgggt tgtccaggta accacgggag ttgtcgctgt
       61 ctaggagcat ctgaaagaca ggtgtgcgtc atgcacttga agcacctgag gaccctgctg
      121 agccctcagg atggagctgc aaaggtgacc tgcatggctt ggtcccagaa caatgccaaa
      181 tttgctgtct gcacagtgga ccgagtggtc ttgctgtatg atgaacatgg agaacggaga
      241 gataaattct ccaccaaacc agctgacatg aagtatggca ggaagagcta tatggtgaag
      301 ggcatggctt tttctcctga ttccactaaa attgccatag gacagactga caacatcatc
      361 tatgtctaca agattggaga agattggggt gacaagaaag tcatctgcaa caagttcatc
      421 cagacgagtg ctgtcacttg tctgcaatgg ccggcagaat acatcattgt ctttggactg
      481 gctgaaggga aggttcgttt agcaaacacc aaaactaata aatcatctac catctatggg
      541 acagagtctt acgtggtgtc cctgacaaca aattgctctg ggaaaggaat tctctctggt
      601 catgcagatg gtaccatcgt taggtatttc tttgatgatg aaggctctgg agagtcacag
      661 gggaagttgg ttaaccaccc gtgtccaccc tatgccttgg catgggcaac caatagcatc
      721 gtggctgcag gctgtgatcg gaaaattgta gcctatggaa aagaaggtca catgctacaa
      781 acttttgatt atagccgtga ccctcaggag cgggagttca ccacagctgt atcaagtcct
      841 gggggccagt ctgttgtgct aggaagttat gacaggcttc gggtgttcaa ctggatccct
      901 cgaagaagca tctgggaaga ggcaaagccc aaggagatta ccaatttata caccatcact
      961 gccttggcct ggaagcggga tggctcacgg ctctgtgtgg gcacactatg tggtggggtg
     1021 gaacagtttg actgctgcct ccgaaggagt atttacaaga acaagtttga gttgacgtat
     1081 gtgggaccta gccaggtgat tgtgaagaac ctgtcatcag gaacccgagt ggtgctcaag
     1141 tcacactatg gctatgaggt ggaagaggtg aaaatcctag gaaaggaacg ttacttggtg
     1201 gctcacacat cagaaacact gctgctgggg gacctgaaca ctaatcggct tagtgagata
     1261 gcctggcaag gatctggtgg caatgagaag tatttctttg aaaatgagaa tgtatgcatg
     1321 atcttcaatg ccggagagct aaccctggtg gaatatggga ataatgacac cctgggttct
     1381 gtacgcactg aattcatgaa cccccacctc atcagtgttc gtattaatga gaggtgtcag
     1441 cgaggaacag aagataataa gaaattggct tatcttattg atattaagac tattgctata
     1501 gtggatctga ttggtggcta caacattggc accgtcagcc atgagagccg tgtggattgg
     1561 ctggaactta atgagactgg acacaagctc ctcttcaggg accggaaact tcgtttgcat
     1621 ctgtatgata ttgaaagctg ctctaagaca atgatcctca acttctgctc ctatatgcag
     1681 tgggtcccag gaagtgacgt gctggtagct cagaaccgaa acagtctgtg tgtatggtac
     1741 aacattgagg cacctgagag agtcaccatg ttcactatta ggggtgatgt tataggtctg
     1801 gagcggggcg ggggaaagac cgaggtgatg gtgatggaag gtgtgactac tgttgcctac
     1861 acattggatg agggcctcat cgagtttgga acagccattg atgatggcaa ctacatccgg
     1921 gcaacagcct tcttagagac tctggaaatg accccagaaa cagaggcaat gtggaaaacc
     1981 ttgagtaaac tggcactaga ggcaaggcaa ctacacattg cggagaggtg cttttctgct
     2041 ttgggccaag tagcaaaagc tcgattcctg catgagacca atgagattgc agatcaagta
     2101 tcccgggaat atggcggaga aggaacagac ttttatcagg tccgagcacg tctagccatg
     2161 ctggaaaaga actacaaact ggctgaaatg atctttttgg aacagaatgc tgtggaggag
     2221 gccatgggca tgtaccagga gctacaccgt tgggatgagt gtatcgctgt ggctgaagcc
     2281 aaggggcacc cagccctgga gaagctacgt cgtagttact accagtggct gatggacaca
     2341 cagcaagagg agcgagcagg tgaactacag gagagccaag gggatgggct agcagccatc
     2401 agcctctacc tcaaagctgg gctccctgcc aaagctgctc ggctggtgct gacccgagag
     2461 gaactgctag ccaacacaga gctggtagaa cacatcactg cagcccttat caagggggaa
     2521 ctctacgaaa gggcaggtga tctctttgag aagattcaca atccacagaa ggccctggag
     2581 tgctaccgta aaggcaacgc attcatgaaa gcggtagagc tggctcgatt ggccttccca
     2641 gtggaggtgg tgaaactaga ggaggcatgg ggggaccacc tggtgcagca gaagcagctt
     2701 gatgcagcca ttaatcacta catcgaagcc aggtgctcca ttaaggcaat tgaggccgcc
     2761 ctgggtgccc gccagtggaa gaaggcaatt tatatattag atctacagga ccggaacact
     2821 gcatccaaat actatcctct cgtggcccaa cactatgcat ccctgcagga gtatgagatt
     2881 gctgaggagc tctatactaa gggagatcgg acaaaagatg ccatagacat gtacacccag
     2941 gctggtcgtt gggaacaagc ccacaagctg gcgatgaaat gcatgagacc agaagatgtg
     3001 tcagtgctat acatcactca ggcccaggaa atggagaagc agggcaagta ccgtgaggct
     3061 gaaaggctat atgtgacagt acaagagcct gatcttgcca tcaccatgta caaaaagcac
     3121 aagttgtatg atgacatgat ccgcctggta gggaagcacc atccagatct cctcagtgat
     3181 acacacctac atctgggcaa ggagctggag gctgaaggcc gactacagga ggctgagtac
     3241 cactacctcg aggcccagga atggaaggca acagtgaaca tgtaccgggc cagtgggctt
     3301 tgggaagagg cctacagggt ggccagaact caaggagggg ctaatgccca caaacacgtg
     3361 gcctatctgt gggcaaagag cctgggagga gaggctgcag ttagactgct taataagctg
     3421 ggactcctgg aagctgctgt tgaccacgct gcagacaatt gctcctttga atttgcgttt
     3481 gaactctctc ggctggccct caagcacaaa acccccgagg ttcatctcaa atatgctatg
     3541 ttcctggagg atgagggtaa attcgaagag gctgaagctg aattcatcag agctggtaaa
     3601 cccaaggagg cagtcctcat gtttgtccat aaccaggatt gggaggcagc tcagcgtgtg
     3661 gctgaggctc acgaccctga cagtgtcgcc gaggtgcttg tgggacaggc ccggggggcc
     3721 ttggaggaga aggactttca gaaagcagaa gggctgctgc tccgggccca gagaccaggc
     3781 ctggccctca attattataa ggaggctgga ttatggagtg acgctctgcg catctgcaag
     3841 gactatgtgc ccagccagct ggaggctctg caggaagaat atgagcggga agctactaag
     3901 aagggggcca ggggtgtgga gggatttgtg gaacaagctc gacactggga gcaggctgga
     3961 gagtacagcc gtgccgtgga ctgctacctc aaagtgcgag actctggaaa cagcggcctg
     4021 gcggagaagt gctggatgaa ggcagctgaa ctctccatca agtttctgcc tccccaacgt
     4081 aatatggaag tcgttctggc tgtaggaccc cagctgattg gaattggaaa gcacagtgca
     4141 gctgcagagc tctatctgaa tctggacctt gtcaaggaag caatcgatgc tttcatcgag
     4201 ggtgaggagt ggaacaaggc gaagcgtgta gctaaggagt tagatcccag gtatgaagac
     4261 tatgtggacc agcattataa agagttcctc aagaatcagg gcaaagtgga ctcgctggtg
     4321 ggtgtggatg tgatagctgc tttggacctg tatgtggagc agggccagtg ggacaagtgc
     4381 attgaaacag ctaccaagca gaactacaag attctgcaca agtatgtggc tttgtatgca
     4441 actcacttga tccgggaggg tagctctgcc caggcattgg ccctgtatgt acagcacgga
     4501 gcccctgcta acccacagaa cttcaatatc tacaaaagga tcttcactga catggtgagc
     4561 tctcctggaa ccaactgtgc cgaggcctat catagctggg ctgatcttcg agatgtcctc
     4621 ttcaacctgt gtgaaaacct ggtgaagtcc agtgaggcaa actctccagc ccatgaggag
     4681 ttcaagacga tgctgctgat cgctcattac tatgccacgc gctctgcagc ccagagtgtc
     4741 aaacagctgg aaaccgtggc tgccaggctt tctgtttcac tcttgcgtca cacccagcta
     4801 ctacctgtag acaaagcctt ctatgaagca ggcattgctg ccaaggcagt tggctgggat
     4861 aacatggcat tcatcttcct caatcgcttt ttggacctga ccgatgcaat cgaggaaggg
     4921 actctagatg gccttgacca ctctgatttt caggatacag acattccctt tgaggtgcca
     4981 ctcccagcta agcagcatgt accggaggct gagagagaag aggttcgaga ctgggtgctt
     5041 acagtctcca tggaccagcg gctggagcag gttctgcctc gggatgagcg tggcgcctac
     5101 gaggcctccc tagtggcagc gagcactggt gttcgagccc tgccctgcct tattacagga
     5161 taccccattc tgaggaacaa aattgaattt aagcggccag ggaaggctgc taacaaggac
     5221 aactggaata aattccttat ggccatcaag acctcccaca gcccagtgtg ccaggacgtg
     5281 ctgaaattca tcagtcagtg gtgtggaggg ctccccagca ccagcttttc ctttcagtag
     5341 ttggtagagc tgaggaagag ttagggcctc tccctcatta aagttttata aataa
//
