LOCUS       NM_001170820            3714 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens interferon induced transmembrane protein 10 (IFITM10),
            mRNA.
ACCESSION   NM_001170820
VERSION     NM_001170820.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3714)
  AUTHORS   Sallman Almen,M., Bringeland,N., Fredriksson,R. and Schioth,H.B.
  TITLE     The dispanins: a novel gene family of ancient origin that contains
            14 human members
  JOURNAL   PLoS One 7 (2), e31961 (2012)
   PUBMED   22363774
REFERENCE   2  (bases 1 to 3714)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC068580.23, DB219779.1, BQ669640.1 and BQ183689.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001170820.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to represent an
            alternative splicing pattern, resulting in an extended N-terminus
            that is more supported by the available transcript data and by
            conservation in primates.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ669640.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340134.5/ ENSP00000344430.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AC068580.23        56747-56747
            2-115               DB219779.1         1-114
            116-812             BQ669640.1         1-697
            813-2990            AC068580.23        72035-74212
            2991-3710           BQ183689.1         13-732              c
            3711-3714           AC068580.23        74933-74936
FEATURES             Location/Qualifiers
     source          1..3714
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     gene            1..3714
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /note="interferon induced transmembrane protein 10"
                     /db_xref="GeneID:402778"
                     /db_xref="HGNC:HGNC:40022"
                     /db_xref="MIM:618293"
     exon            1..237
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..840
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /note="dispanin subfamily A member 3"
                     /codon_start=1
                     /product="interferon-induced transmembrane protein 10"
                     /protein_id="NP_001164291.2"
                     /db_xref="CCDS:CCDS53593.2"
                     /db_xref="GeneID:402778"
                     /db_xref="HGNC:HGNC:40022"
                     /db_xref="MIM:618293"
                     /translation="MREGKRGPPCILSFRGTLERVEAQWELEAQGPGQCPAPLGDPAS
                     TTDGAQEARVPLDGAFWIPRPPAGSPKGCFACVSKPPALQAPAAPAPEPSASPPMAPT
                     LFPMESKSSKTDSVRAAGAPPACKHLAEKKTMTNPTTVIEVYPDTTEVNDYYLWSIFN
                     FVYLNFCCLGFIALAYSLKVRDKKLLNDLNGAVEDAKTARLFNITSSALAASCIILVF
                     IFLRYPLTDY"
     exon            238..690
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /inference="alignment:Splign:2.1.0"
     exon            691..3714
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1298..1303
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /note="hexamer: AATGAA"
     polyA_site      1320
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /note="major polyA site"
     regulatory      3686..3691
                     /regulatory_class="polyA_signal_sequence"
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /note="hexamer: AATAAA"
     polyA_site      3714
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
ORIGIN      
        1 gagaaagggt tcagagtcag gcacaggcag gcagacagga ccccaagcag gactggcctt
       61 ccagacagga aagagggttg cggagacaca ggaggccagt tgagagtggc agaggagaaa
      121 ggagtttcat gggaggatgg ggcttggaga gagatgaggg agggaaaacg ggggccgcca
      181 tgcatcctca gcttccgggg gactttggag agggtcgagg ctcagtggga gctggaggcc
      241 cagggccccg gccagtgccc agccccgctg ggagacccgg ccagcaccac ggacggcgcc
      301 caggaagccc gagtccccct ggacggggcc ttctggattc cgaggccccc ggcaggttcg
      361 cccaagggct gcttcgcttg cgtgtccaag ccccctgccc tgcaggctcc ggcggcccct
      421 gcccctgagc cctcggcctc tcccccgatg gcgcccacac tgttccccat ggagtccaag
      481 agcagcaaga ccgacagcgt gcgggctgcc ggcgcgcccc ctgcctgcaa gcacctagcc
      541 gagaagaaga cgatgaccaa ccccacgacc gtcatcgagg tctacccgga caccaccgag
      601 gtgaacgact attacctgtg gtccatcttc aacttcgtct acctcaactt ctgctgcctg
      661 ggcttcatcg ccttggccta ctccctcaaa gtgcgagaca agaagcttct caatgacctg
      721 aatggagccg tggaggatgc aaagacggcc cggctgttca acatcaccag ttctgccctg
      781 gcagcctcct gcatcatcct cgtcttcatc ttcctgcggt accccctcac cgactactaa
      841 ggcccgccag gcacggctgc tggcggagac aagcactgag acatgtttat tctcatggtc
      901 cctgaaacgc aggatcccat gaggttgggg cagggcaggg cttcttgtcc tggggccccc
      961 ttgagctgtg aactgggcag caaggccatc agaagctgag tacagcaagg gggcagtgag
     1021 cttggccctc agtccacccc ctccgcctcc tggcctccac cctgcctgtg tctggggcct
     1081 gggggcttct cccctcgctg ctgcaccctg gcttccagcg tctgtgtccc tgccctcacg
     1141 tgccccttcc caggctcctg gggccccttg gacctgacac ctagcaggaa gggcttatgc
     1201 aaaattgtcc caggttggga ggactcactc tgtgctcccc gaccctgcct cctccacgat
     1261 gtgaccccgc tcagagccct tgtgtctgtg aactttcaat gaaataccca tgcagctcca
     1321 gcccagcctt ctactttgtg tccctggcag ggcctggaga agtctggagg ctttgcaatc
     1381 ctccctcagg aactgcctgg cggtcagggc cccgggtgct gtgtcccaac agactgcagg
     1441 ggacggtctg ctccatcaca gctgtgccag acagtgaatg ggaagggggg gcatttggtg
     1501 gaggtacccc aaactcgagt cacttagagg gtcaggcagc ctcctggggg gacggaaggg
     1561 ggtggggcac agcctcagct gcctgcattg gccaaatcag agcaaaggaa accacaaatt
     1621 cactcggaag gaagcagcag gcagagacga tagacgcctg gctaacccct gtccctcctg
     1681 gagggctctg ggacctggac aggccccttt acctctctcg tgcccatctc cttagctgta
     1741 aaataggaaa atggcctttc acttctataa tcactgtgaa aatgaacgga agatgccttt
     1801 caaaggccga ggccagcgcc ctgacggccc atggcatgtg cagtccacaa tgtgggaggc
     1861 aggatgcagg gatgggctct gtccccttgg aactcaggca cagtcatggg ggtgccggtc
     1921 agccctgaag acaagctgat gagggtgcac taggaaaagt gcagggcatc ggcgaggcac
     1981 acgaaggagg tggggaggtg aagatggaga agaagccgag gcagtggcca tgggtgtgga
     2041 gcttcgcgct gtgggtgccc agctggtctg ggaaaccgca ggaaatcccg cagctcaggt
     2101 gcgcagtggg aaggacttgc tattccgtgg gaaggcaggc aaaccttccc agggaagggg
     2161 catggccgtg cgcctcatgt tttgggaagc tcgtgccctc tggggtagcg aggccagctt
     2221 ggaggggagt ccagtggaca gaggtggatg caagtggagg gagctgagcc tgggctgggg
     2281 ctggcagcag agggctggac agcagggcgc ctgcgtggca gctgtgcagt cagtggggtt
     2341 gactggtttg gaaggtaagg tgggggagaa gcccggagga ttcctgtccc ttgacttgga
     2401 cagcccagtg gagagggctg tgtaccaagg gcaggaaacc agggagaaga agatgttgac
     2461 tttaagatac caagcagaga agggaagagc cttctgggct ggagacgtgg ggtgcctcag
     2521 aagggaggac cttgagctag cagcagatgg gacaaacgca ggggacaggg cacagccgtg
     2581 gcaggagtgc agcgagcaag attctggtca cagtcctgac ccagaaacct gcagaggaag
     2641 ggagggtggc cagcacctgc ccgtgggcct ggggtgcagc ccaggcagag gtggatggag
     2701 ggggtgctca gggaagaggg gaggggagtg tgtgacctca aaatgggagg gcttgggggt
     2761 cagagtcgag agaggggaca gggtggggac catgtgggac tcttgagcac tgacccttga
     2821 acccaggcag tggtgggatg ggagggcagg aggcggcggg ctgcgaggct gatgcggggc
     2881 tgcacggagc tgtcattgag cctcttggag gatggtggga gaagtgccag gggcggctga
     2941 aagccttgcc gagactgtgg gcagcctggt tgtgggcact tcggatgctt gcaccattag
     3001 acccagaggc ttcctggaca agcctgggct ggaagaggat ggcagaggct gctgggcctt
     3061 ggaagagaga gggtcctggc ttctagttcc tggggcagct aaggccaacc ccagtgtcca
     3121 ggtgtcttcc atgttatgcc tgggagggaa gaaagtagag gggcaaatgc tttctttgcc
     3181 tattttcctt aaacatttgg tggcagtgct ggtggctgcc tgggacaggg gccaggagga
     3241 aacacccctg cattagggaa gccctcagcc agcttttccc tgggatgttc ctgcgcctgg
     3301 ctgaagcttt ctgagttcat gttggggaaa tggaacggtc accttccagc cagtaaaggc
     3361 acccctagct cttgggatgt ttgtatccaa ctccgggcaa tgtggggcta caaaggcccc
     3421 tggcttccat accctgggga ccgggggagg gctggtgctc ccgcggtggg tgtccacggt
     3481 gaggtcaggc ccccacagca ggtgcattct cgccctcagc aggcaggcaa gcaggcatca
     3541 gctccggcgc tggtctctgg cttcgaagtc tgtgtctttg cctgtctgta ctcatgcctg
     3601 acctgctggc gctccctgtc cactgcactc ctcccacctc atttttatgt gattttgcac
     3661 agtgcctggc agacatttga cattcaataa acattgtacg aacgaaagaa tcaa
//
