LOCUS       NP_001164291             228 aa            linear   PRI 27-APR-2025
DEFINITION  interferon-induced transmembrane protein 10 [Homo sapiens].
ACCESSION   NP_001164291
VERSION     NP_001164291.2
DBSOURCE    REFSEQ: accession NM_001170820.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 228)
  AUTHORS   Sallman Almen,M., Bringeland,N., Fredriksson,R. and Schioth,H.B.
  TITLE     The dispanins: a novel gene family of ancient origin that contains
            14 human members
  JOURNAL   PLoS One 7 (2), e31961 (2012)
   PUBMED   22363774
REFERENCE   2  (residues 1 to 228)
  AUTHORS   Taylor,T.D., Noguchi,H., Totoki,Y., Toyoda,A., Kuroki,Y., Dewar,K.,
            Lloyd,C., Itoh,T., Takeda,T., Kim,D.W., She,X., Barlow,K.F.,
            Bloom,T., Bruford,E., Chang,J.L., Cuomo,C.A., Eichler,E.,
            FitzGerald,M.G., Jaffe,D.B., LaButti,K., Nicol,R., Park,H.S.,
            Seaman,C., Sougnez,C., Yang,X., Zimmer,A.R., Zody,M.C.,
            Birren,B.W., Nusbaum,C., Fujiyama,A., Hattori,M., Rogers,J.,
            Lander,E.S. and Sakaki,Y.
  TITLE     Human chromosome 11 DNA sequence and analysis including novel gene
            identification
  JOURNAL   Nature 440 (7083), 497-500 (2006)
   PUBMED   16554811
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC068580.23, DB219779.1, BQ669640.1 and BQ183689.1.
            
            On Jun 4, 2011 this sequence version replaced NP_001164291.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            CCDS Note: The coding region has been updated to represent an
            alternative splicing pattern, resulting in an extended N-terminus
            that is more supported by the available transcript data and by
            conservation in primates.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BQ669640.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000340134.5/ ENSP00000344430.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..228
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11p15.5"
     Protein         1..228
                     /product="interferon-induced transmembrane protein 10"
                     /note="dispanin subfamily A member 3"
                     /calculated_mol_wt=24468
     Region          29..49
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (A6NMD0.1)"
     Region          151..217
                     /region_name="CD225"
                     /note="Interferon-induced transmembrane protein;
                     pfam04505"
                     /db_xref="CDD:461336"
     Site            155..175
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (A6NMD0.1)"
     Site            201..221
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (A6NMD0.1)"
     CDS             1..228
                     /gene="IFITM10"
                     /gene_synonym="DSPA3"
                     /coded_by="NM_001170820.4:154..840"
                     /db_xref="CCDS:CCDS53593.2"
                     /db_xref="GeneID:402778"
                     /db_xref="HGNC:HGNC:40022"
                     /db_xref="MIM:618293"
ORIGIN      
        1 mregkrgppc ilsfrgtler veaqweleaq gpgqcpaplg dpasttdgaq earvpldgaf
       61 wiprppagsp kgcfacvskp palqapaapa pepsasppma ptlfpmesks sktdsvraag
      121 appackhlae kktmtnpttv ievypdttev ndyylwsifn fvylnfcclg fialayslkv
      181 rdkkllndln gavedaktar lfnitssala asciilvfif lrypltdy
//
