LOCUS       NM_001136180             689 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens heat shock factor binding protein 1 like 1 (HSBP1L1),
            mRNA.
ACCESSION   NM_001136180
VERSION     NM_001136180.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 689)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA919112.1, BC157848.1, AC114341.9, BC040056.2 and CA444419.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001136180.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BX397585.2, SRR1163655.120249.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000451882.3/ ENSP00000414236.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                DA919112.1         62-78
            18-257              BC157848.1         1-240
            258-258             AC114341.9         169043-169043
            259-452             BC157848.1         242-435
            453-673             BC040056.2         438-658
            674-689             CA444419.1         17-32               c
FEATURES             Location/Qualifiers
     source          1..689
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="18"
                     /map="18q23"
     gene            1..689
                     /gene="HSBP1L1"
                     /note="heat shock factor binding protein 1 like 1"
                     /db_xref="GeneID:440498"
                     /db_xref="HGNC:HGNC:37243"
     exon            1..144
                     /gene="HSBP1L1"
                     /inference="alignment:Splign:2.1.0"
     CDS             94..318
                     /gene="HSBP1L1"
                     /codon_start=1
                     /product="heat shock factor-binding protein 1-like protein
                     1"
                     /protein_id="NP_001129652.1"
                     /db_xref="CCDS:CCDS45886.1"
                     /db_xref="GeneID:440498"
                     /db_xref="HGNC:HGNC:37243"
                     /translation="MDVRGPEAPGGRALRDAAENLFQELQEHFQALTATLNLRMEEMG
                     NRIEDLQKNVKDLMVQAGIENSIKEQMLKT"
     exon            145..211
                     /gene="HSBP1L1"
                     /inference="alignment:Splign:2.1.0"
     exon            212..306
                     /gene="HSBP1L1"
                     /inference="alignment:Splign:2.1.0"
     exon            307..689
                     /gene="HSBP1L1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      653..658
                     /regulatory_class="polyA_signal_sequence"
                     /gene="HSBP1L1"
                     /note="hexamer: AATAAA"
     regulatory      664..669
                     /regulatory_class="polyA_signal_sequence"
                     /gene="HSBP1L1"
                     /note="hexamer: AATAAA"
     polyA_site      673
                     /gene="HSBP1L1"
                     /note="major polyA site"
     polyA_site      689
                     /gene="HSBP1L1"
ORIGIN      
        1 atacgggaat cgcggagctt agctgtcgcc acctcgcgcc gggtccgcgc ggcccacggg
       61 accccccact gacgcccccg gccagcggtc cacatggacg tgcggggccc tgaagccccc
      121 ggcgggcgcg cgctgcggga cgcggcagaa aatctatttc aggaacttca ggaacatttt
      181 caagctctga cggcaacatt aaacctcaga atggaagaaa tgggaaatcg cattgaggac
      241 ttacagaaga atgtcaagga cttaatggtg caagctggca ttgaaaattc tattaaagaa
      301 caaatgctga agacctaact gcagcatgtc tgtatttgga gatggggcct ctacagaagt
      361 cattaaggtt acatcggtcc tgagggtggg gccctcatcc aacaggattc gtctttctga
      421 gaagagacgc aaggggctcg cctgctctcc cctccgtgcc tgcaccagag aaggaggcca
      481 tcggcaagcc aaggagagcc ctccccagaa atcacacgga ccagcacctt gatctgggac
      541 ttccagaaaa cagaactgtg aaaagacaag tttctgttgt ttaaaccacc caatctgaag
      601 tattttgtta tggcagtcct gggcagacta atacaatatg caacacattt acaataaata
      661 tacaataaac ttacaaatgt ggaatgtaa
//
