LOCUS       XM_047441571            4183 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens HPS4 biogenesis of lysosomal organelles
            complex 3 subunit 2 (HPS4), transcript variant X19, mRNA.
ACCESSION   XM_047441571
VERSION     XM_047441571.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000022.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4183
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
     gene            1..4183
                     /gene="HPS4"
                     /gene_synonym="BLOC3S2; LE"
                     /note="HPS4 biogenesis of lysosomal organelles complex 3
                     subunit 2; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 51 ESTs, 248 long SRA
                     reads, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 26 samples with support
                     for all annotated introns"
                     /db_xref="GeneID:89781"
                     /db_xref="HGNC:HGNC:15844"
                     /db_xref="MIM:606682"
     CDS             589..2610
                     /gene="HPS4"
                     /gene_synonym="BLOC3S2; LE"
                     /codon_start=1
                     /product="BLOC-3 complex member HPS4 isoform X7"
                     /protein_id="XP_047297527.1"
                     /db_xref="GeneID:89781"
                     /db_xref="HGNC:HGNC:15844"
                     /db_xref="MIM:606682"
                     /translation="MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQ
                     TLLDQQELLCGQIAGVVRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPD
                     VSCKRFLDQLVGFFNFYNGPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSL
                     WNLDQTKVEPLLLLKAARILQTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRT
                     APQEQRLPTGEDAPQEHGKWMLWSFKNRVTHQNPNGAALPPNVQIIPVFVTKEEAISL
                     HEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGHVESMAWTTPDPTSPDE
                     ACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKELVFLQEELDLSEIHI
                     PEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPE
                     MLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRGNKLPTGEQGL
                     DEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVRMNLYTHCV
                     KGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSSTYNFTH
                     YDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVSCTS"
ORIGIN      
        1 ctctctgccg cgcgcgcagg tacggggcag aagtcgcagg tacccagctg ctgcccacat
       61 ttctggtcca gagtcccgaa ccccgagcac tgggatgcct ggctactccg agccaaggca
      121 ctgatgtttg aactggaaac ttcaaaacgt ttaataagag tcttcaggat gggtttgaac
      181 tagacaagct agaaatttct ttagaacacc agctctagca tgcatctccc acttttggct
      241 ttcctggaga ggagcttgaa gaggtggttc tgcagacagc cacagtgata cttaggaaac
      301 cagaggaatg gatttgactt ttctgctagg attctctgtt atagtttctc cctgagttgt
      361 aagaggcatg gaaatataca tgaaactgaa gaacctgcaa ggaagggaag tggaactttc
      421 catgctgagt gaaaactaac caagtggcag ttgtgactga aaacactgaa acctaccacg
      481 tccagattca ctggattggg ggatagagga acggtcacag ctagggagaa agaagtgata
      541 ccggaaaaga aaacctaaat gaagagaatg aggatgactg cacagtagat ggccacctct
      601 acctccacag aggcaaagtc agcctcgtgg tggaattatt tttttcttta tgatggttcc
      661 aaggtaaagg aagaaggcga tccaacaaga gctggcattt gttactttta tccttcccag
      721 accctgctag accaacagga gttgctttgt ggacagattg ctggagttgt ccgctgtgtt
      781 tctgacattt ctgactctcc tcctactctt gttcgtctga gaaaactgaa gtttgccata
      841 aaagttgatg gagattacct ttgggtgctg ggctgtgctg tggagctccc tgatgtcagc
      901 tgcaagcggt ttctggatca gctagttgga ttctttaatt tttacaatgg acctgtttcc
      961 ctagcttatg agaactgttc tcaggaagaa ctgagcacgg agtgggacac cttcatcgag
     1021 caaattctga aaaacaccag tgatctgcat aagattttca attccctctg gaacttggac
     1081 caaactaaag tggagcccct gttgttgctg aaggcagccc gcattctgca gacctgccag
     1141 cgctcgcctc acattctcgc tggctgcatc ctctataaag gactgattgt cagcacccaa
     1201 ctcccgccct ccctcaccgc caaggtcctg cttcaccgaa cagcacctca ggagcagaga
     1261 ctccctacgg gagaggatgc cccgcaggaa catggaaaat ggatgttatg gagcttcaag
     1321 aatcgagtta cccaccagaa ccctaatgga gcggcattgc ccccgaatgt ccagattatc
     1381 cctgtttttg tgaccaaaga ggaagccatt agtctccacg agttcccggt ggaacagatg
     1441 acaaggtctc tagcatctcc agcaggactc caggatggtt cagcccagca ccatccaaag
     1501 ggtgggagca catctgccct gaaagaaaac gccactggcc atgtggaatc catggcctgg
     1561 accaccccag atcccacatc ccctgacgaa gcttgtccag atggcaggaa ggagaacgga
     1621 tgcttgtctg gccatgatct ggagagcatc aggcccgcag gactgcacaa ctctgccagg
     1681 ggtgaggttc ttggcctcag ctcctccctg gggaaggaac tagtctttct ccaagaagaa
     1741 ctcgacttgt ctgaaatcca cattccagag gctcaggaag tggaaatggc ctcaggtcat
     1801 tttgccttcc tacatgtgcc tgttccagat ggcagggctc cttactgcaa ggcatctctc
     1861 agcgcctcca gcagcctgga acccacgcct cctgaggaca cagccatcag cagcttgcgc
     1921 cctccctctg ctcctgagat gctgacccag catggagccc aagagcagct cgaagaccat
     1981 cctggccata gcagccaagc ccccattccc agagcagacc ctctccccag aaggacccgc
     2041 aggcccttgt tattgcctcg cttagatcca ggacagagag gaaacaagct tcccacgggg
     2101 gaacaaggcc tggatgagga tgttgatggg gtctgtgaaa gccacgcagc ccctggtctg
     2161 gaatgcagtt caggctcagc aaactgtcag ggtgctggcc cctctgcaga tggaatcagc
     2221 tccaggctga caccagcaga gtcctgcatg gggctcgtga ggatgaatct ctacactcac
     2281 tgcgtcaaag ggctggtgct gtccctgctg gctgaggagc cgctgctggg agacagcgca
     2341 gccatagagg aagtgtacca cagcagcctg gcttcactga atgggctgga agtccacctg
     2401 aaagagacgc tgcccaggga tgaggcagcc tccacgagca gcacctacaa cttcacacat
     2461 tacgaccgca ttcagagctt gctgatggca aacctgccgc aggtggccac cccgcaggat
     2521 cgccgcttcc tccaggccgt cagcctgatg catagcgaat ttgcccagct gcccgcgctt
     2581 tatgaaatga ctgtcagttg tacctcttag aagctgctgt tttccatttg gatctaaaca
     2641 ctggacctgc acctgcgacc agctgtatat tccaaaccac tcctcggctt tataaatctg
     2701 acactgctca taatacatta ttcagaaaag gcatctctag tgtggctggc cggctacgct
     2761 ttcacacatc agctaacaca ggctatttct agagtgagtg cctcaaactg gtctcctggg
     2821 accttttcct tcgggaagag atccacatgt tcttcacagg agaccagaaa accagcacaa
     2881 cggccacggg tcctctgggc atgtaggtct tctctgtctc ctcactagca cacactggct
     2941 tgggtcattg tcacgcagtg cacacctttg tgccatgaca aagacacagg gccaactctt
     3001 ccactatctc caagtctagt gtttgaacat ttatgtacag acaaataaat gaaaaaaaaa
     3061 aaaacatagg caacagaact ccaaagcaaa acagaaactt tggtcagatc tattattcca
     3121 gttttgccag agaaaggctt tccccaaatg tcgctgggtg agcgcggtcc tatcccccta
     3181 cagctcctat cagccaacct ggtggcctta acgttcatca ctgtggactc aaaacaccta
     3241 aaactgggaa ttttccaggc ccagtttggc agtagggctt ctgtaggcag tgaggtaagc
     3301 ggatcacacg ttccgtggct gatctgtgtg agccgcagct tggtgctggg ggacaccagc
     3361 ttcagctttg caggaaagcc atgtttaaag agtagcctcc agtcctactg gcccaatgct
     3421 tttgccatca gggacctgac aaggtttaga atgaggtgag cgatggtgac agtatccctg
     3481 ggcctggaca ctgtgtgcca ccctgactgt gtctggcagc ccctccacct ggctactgaa
     3541 gccagtcagg tgtgggggct gcagactgtc cccctgccgt caggtggctg aagggtcccc
     3601 agtgtgccag catcagaggc caagttctct agctctctgg tttgcagttt ttagtttttt
     3661 tttttttttt ttaagatgac cacaagaagt tttacattat tatattcaga caaataacca
     3721 tttagttact ctatttcaga gcactgaaaa aaacaagtag caacagaaga cagacttaca
     3781 agggcactaa gtctctggtc actcaaggac caatcaaagg aatgcgctgt taggccagaa
     3841 aggagtctct gaagcaaatg attggaagga aaaaaaaaaa atctaaggaa atacaagccg
     3901 aaaagtttcc atttacaata accaagggaa agagggaccc gacatgatat aaaatcccaa
     3961 ataagagctt tccgctgagg caggtttctg agcatggaaa caacaccggt agggactgga
     4021 ccggaccaca gtctgcccag gccccgcctc ggcccttctc gccgactcca gcatgggaaa
     4081 tactctcatc gtcccggagc aaagatgaaa tcaagagcct gccgttcggc cgctgcgacg
     4141 tttggatgcc acaaatccac catgaaaacc acccgtgggc cat
//
