LOCUS       XM_047435904            6513 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens homeobox B3 (HOXB3), transcript variant X6,
            mRNA.
ACCESSION   XM_047435904
VERSION     XM_047435904.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6513
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6513
                     /gene="HOXB3"
                     /gene_synonym="Hox-2.7; HOX2; HOX2G"
                     /note="homeobox B3; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 9 ESTs, 145 long SRA
                     reads, 11 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 16 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:3213"
                     /db_xref="HGNC:HGNC:5114"
                     /db_xref="MIM:142966"
     CDS             3757..5049
                     /gene="HOXB3"
                     /gene_synonym="Hox-2.7; HOX2; HOX2G"
                     /codon_start=1
                     /product="homeobox protein Hox-B3 isoform X4"
                     /protein_id="XP_047291860.1"
                     /db_xref="GeneID:3213"
                     /db_xref="HGNC:HGNC:5114"
                     /db_xref="MIM:142966"
                     /translation="MQKATYYDNAAAALFGGYSSYPGSNGFGFDVPPQPPFQAATHLE
                     GDYQRSACSLQSLGNAAPHAKSKELNGSCMRPGLAPEPLSAPPGSPPPSAAPTSATSN
                     SSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTEGCGGGGGGGG
                     GGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRV
                     EMANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMN
                     ALHSMTPSYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQ
                     ANGGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMA
                     PSQHHGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL"
     polyA_site      6513
                     /gene="HOXB3"
                     /gene_synonym="Hox-2.7; HOX2; HOX2G"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 ctgggtaggg cagggggaac cgacaggccg gtgtccccag ccgcaaaaga gctgctgaac
       61 tgtccgttta aatgctgctg ggagactcgt aaaaaaatca tcgtggacct ggaggatgag
      121 aggggcgagc tttatttcgg tcggattgcg gtgtggtggt ttagctgcaa ggggatgccg
      181 cagccccagt tgagggggaa aatagttctt aaaaagcata tgccccccta aggaatgtct
      241 ctaaagaacc aaatcaaagc tgctctttgg aaggtatgaa tagaatttaa aaaaaaaaga
      301 tttctatgga gcttaaagtt cacagccatt ctgtgtagac aagagctaag aaaaatgtga
      361 gaattataca gaaaaccatt aatcacttct tttctttaaa tacgtatcct ctctcctttg
      421 ttattattca acagcaaatc tccttggacc ggctgttggg ggaaaaaagt gttagccgtc
      481 tctcccggat ctgcaagggg gaaaaaattt ggaaccataa agttgaaaac ttttttctct
      541 cagtttggaa gaagcccttc gtcatgaatg ggatctgcag agttcgggcg agaggaggcg
      601 agaggcgcaa aggaggggag atttgtcgcc tgccgctcgc tctggggctc gatgtgaata
      661 tatattatgt ctgcctgttc tcccctcgtc ggtggctaag gtaagctgga ctgaaatagg
      721 ctatcagttt gtgaatggcg gagagtatgt ctcaatgatt tatggcccat atgactccaa
      781 tctcggttca agaagagttc acaagcttta agcttccttc cacgcagcga ctctctctct
      841 ccctccctcc ctccctccct ccctccctct ctctctctct ctctctctct ctctccctct
      901 ctctctcccc tctctcttcc tgcttctctc ctcttttctc ctctctctct tttctttcag
      961 cagccagatc cagggctgaa ttttctccgc ggctgctaag aaagtctcaa cctttctctg
     1021 tcttcctttc ttgttatttt tctttctccc attaattttt ttaagtcctg gaagatggcc
     1081 tatcccctct ctcggggctt ccccagctat tgttactctc ctggctctcc ctggggtgtg
     1141 cttggcaagg tggggttctt gcggggggct catctccctt ctccagcgag accctggggg
     1201 gaagccggca gccaccgtct ccctccctcc ctcccgagga gccatatgga acctgaattt
     1261 ttccaacatg gaggcaaggg aaatagatct gtttggcttg gtagagttgt tccccacccc
     1321 ctcttgttct ggatcccaga tcttgggtcc ccttagcacc tttctctctt cccactgtcc
     1381 cgtccgccag gcctcggcgc cctccaaccc ggagccctgc tgagcaaagt cccgaagcgg
     1441 agtttctaag gcgcctttta attcggttac ctccagctcc caaaacttgc tgccgcccgc
     1501 ggggctcggc cctcggccgg ctggtgtgct gggaacctgc ctccgataac cgttttggtg
     1561 tcctgatcgc ttgctcttct tcgcctcctt gggccatcgt aggtggctgg tagcttgtcg
     1621 ccagtcgccg cggcagcagc gaccggctga ggcagcctgg cagcagcagc cagggactac
     1681 ccgggtgcac aaaccttccc agccctgtct gcaccaccgg cggagtctcc attctttcct
     1741 atcgcgtctc tggctccttc gctttccaca ctcgcctggc ctccgtcccg cgatggtttg
     1801 gggtttattg caaggggagc ggcaggaatt tcggccccag gcatctagtt aaattattgt
     1861 tttattatta ttactatcat catcatcgtc atcattatta ttgctgtaac aatcagacta
     1921 aataaagcca gggcctagcc agccaacccc ctccaacgtt tttatttcat tctcttctct
     1981 attaataaca accacaacta atgcctgtta attaattccc ccttcagcca gggctgcttg
     2041 gaagctaatt ttggttaaat cagcagaggc taatggtaat aataataaag ggattgggtc
     2101 agcctggtca attgaactct ggttctccct ggaaggacct gctgctttgc agacccatgt
     2161 gtatttccag aaaccaatcg gaactcaggg ttacactgat tcccttttga gtataaatct
     2221 gtgccatgaa gaaggggatt tatgtgaggg agggactttt cttcacctgc actcctttta
     2281 ttttattttc ctatgtttag ttttctttgg agttgaacag ctaggctgaa tgagattaaa
     2341 gttttccaaa cacacatggc agtatggagg ttttatgaaa agtgatggtg aagagttggg
     2401 agagatggag ggaaaaaaat gcagtcagaa gtttcagaac aaatacacaa aatcctatgt
     2461 tagtttgaat ctttattttt ctggcacact tttaaaaggc tgtattaaaa tagtgatttt
     2521 ttttttttgc ctcagggaac ctcagtcaac aggaatacct ctgtttctaa cctagagaat
     2581 aatattgtta aaattgcttt gttaattttt ttttcctcag gaataatttt ctcttttgga
     2641 aagcactttc cccgtctcag tagaaaagtc tagcagttgt aacttcttgt ttcttatttg
     2701 ctttggggga aatcaaagaa aacagacggt gaaggaaagg gtgggaaaaa ttaagtctca
     2761 tgaaaaaaaa aaaaagaggt ccggggagag acctgggcca aatggtcaca gcaccaactg
     2821 gcgtggccca ggaaattgaa acaatcctgc tccatgtggg ggccccacag ggccactggc
     2881 tgcccgatcc caggtttggc tgagcaaaga caagggctgg aggtggtggt acctgcagca
     2941 gggccatgga cagatgagtc tcggttcagc tggctcttga ggttaaaaat catcaggaag
     3001 tttctaggtc aggctgttgt tgtcttcctg gtgggagagt ggtgggaagt ggagaggata
     3061 cctcacaaga gaagcttctc tgctgaactt gcttctcctg cctgttcttt taggagatcc
     3121 tttggttttc cttcaggcta gactttgctt gggcaagaga cctaaaccga cttggaagga
     3181 ggcaaaggct ggaagcatag aagcctctgg gctcagagga gggtgttgat gatgctttta
     3241 ttttggagtc tcctagtgtc ccctcccttg agccatccta tcccagagtt ggggaggaga
     3301 gatagggaga gagggactag gggaggtcag gggctagtgc acaggcagga gagaagcaat
     3361 ggcctttgcc atagattcta catctaggca gtcttgaaag gcatatagtc tttatttatt
     3421 tttttatttt ttagtggaaa tgaaaactgg tgggcttttt tttctcagca tctgctttgg
     3481 agatgttggg gaggggaaaa gaaaaaaccc tattgatgtc agttcccttt tcagttccta
     3541 agatggattc gagccccagt cctcttctcc cccttgtgtc tcttctctcg cctcgcaggt
     3601 cagccgcttg gaacagaccc cggaggaggg gggcagagag gggaggtggg gggggggggt
     3661 ccggcgtgtc acgtgacccc cagggttgcc aatgtccggt cctgagggta tcaggccttt
     3721 ccaagttgcc acccactgcc caggcctcac ccagcgatgc agaaagccac ctactacgac
     3781 aacgccgcgg ctgctctctt cggaggctat tcctcgtacc ctggcagcaa tggcttcggc
     3841 ttcgatgtcc ccccccaacc cccatttcag gccgccacgc acctggaggg cgactaccag
     3901 cgctcagctt gctcgctgca gtccctgggc aacgctgccc cacatgccaa gagcaaggag
     3961 ctcaacggca gctgcatgag gccgggtctg gcccccgagc ccctgtcggc cccgcctggc
     4021 tcacccccgc ccagtgccgc acctaccagt gccactagca acagcagtaa tgggggcggg
     4081 cccagcaaaa gtggtccccc aaagtgcggt cccggcacca actccaccct caccaaacag
     4141 atattcccct ggatgaaaga gtcgaggcaa acgtccaagc tgaaaaacaa ctcccccggc
     4201 acagagggct gtggtggcgg cggcggtggc ggcggcggcg gaggcagtgg tggcagcggg
     4261 ggcggtggcg gcggcggcgg gggaggggac aagagccccc cggggtcggc ggcgtccaag
     4321 cgggcgcgga cggcgtacac gagcgcgcag ctggtggagc tggagaagga gttccatttt
     4381 aaccgctacc tgtgccggcc tcgccgtgta gagatggcca acctgctgaa cctcagcgag
     4441 cggcagatca agatctggtt ccagaaccgg cgcatgaagt acaagaagga ccagaaggcc
     4501 aagggattgg cctcgtcgtc ggggggccca tctccagccg gcagcccccc gcagcccatg
     4561 cagtccacgg ccggcttcat gaacgcctta cactccatga cccccagcta cgagagcccg
     4621 tccccacccg ccttcggtaa agcccaccag aatgcctacg cgctgccctc caactaccag
     4681 ccccctctca aaggctgcgg cgccccgcag aagtaccctc cgaccccggc gcccgagtat
     4741 gagccgcacg tcctccaagc caacgggggc gcctacggga cgcccaccat gcagggcagt
     4801 ccggtgtacg tgggcggggg cggctacgcg gatccgctgc cgccccctgc cggcccctcc
     4861 ctctatggcc tcaaccacct ttcccatcac ccttccggga acctggacta caacggggcg
     4921 ccccctatgg cgcccagcca gcaccacgga ccctgcgaac cccaccccac ctacacagac
     4981 ctctcctctc accacgcgcc tcctcctcag ggtagaatcc aagaagcgcc caaattaaca
     5041 cacctgtgat gggaaagggc gaacgaggat taggggatgg ggaggaagag agagactgtg
     5101 gagctctggg gggcaacctg gaggtctgaa aagaggagcc agagaaggtg gtacccaggc
     5161 ttcctggtca gaaccggcct ggagctcctt cccttccccc tggcctgaga ggttgctttt
     5221 aagtcttcca ccccttgttc catctgcctg ccaacccatc ggaaaggaat ccacatcata
     5281 ttggagatga ccccatcaac cccagggctc cagcactacc aagttggaat tccacgcccg
     5341 ggagtggggt agaggaagac gagacaggac gaggcagaaa agcacatttt aaaaaccaga
     5401 caagatggct aggccatcac caaccaacgg acttacctta catctttgta ggtaattccc
     5461 cccaaatctt gatttttttt tttcctcaat tatcctttaa aaaataagaa aacacatttc
     5521 aaacccaaaa ggcacaaaac acgttccctt ccaactttcc caaaacctca aatttgttcc
     5581 catttgaggt ttattgaggt acacttctag cccccggttt ttctgctcta gaacattcat
     5641 atctatacat cccaccccca tcaattacag tttttagagg gctcagggat ggtgagagat
     5701 cctgaaagag ctgcctatat tataaattat atacattttt ttttaaggaa aagtgtggag
     5761 gctagggcag gcaggttgtt aggactgaag gtttgcccat tctgctgcct ccatctcagc
     5821 tccagctcca tccccctctc cacagaaagc agttggtgac acgaggttct atacttttct
     5881 tctgttgctc tcttgactta acgtgaaaac agggtatatt tgaacaaact gtcccaggca
     5941 ggggctgggc agggcctgtg tgccttgctc agcctcctga caggacactt ttgttgcact
     6001 tagaatttac attttaatgg atgtaaaaac aactgtgaga gatgtctggg cctgcagaag
     6061 tccagcattg ctcaaaaaag cgtgtgttct agtgaacatt ttcatatata tttattggtt
     6121 atagcctgtt aaaatatttt cttttttgta ttatttatcc ccctacatta tgtatttata
     6181 tgagggaaaa aaaggaaaaa attgtacttt tttagtattt acctgttaca aaggacattg
     6241 tgtttcctgt catgtaaaac cagctatttt agttactatt gtactctaga aaagagctgt
     6301 agatttatgt taaactcgta cttacgaaca attgtaatta gttctaaaag gcatgaactc
     6361 agctcctaat cgtcactgta tagtcctgaa tttgtagaac tagagttaat tccctcttgg
     6421 aactttcttt gttcttcagt agttactttt ttccttacct aaaagggttg tctgtcaaac
     6481 aattcttgaa taaactttct gttatcaatt tta
//
