LOCUS       XM_006711441            3759 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens hedgehog acyltransferase (HHAT), transcript
            variant X2, mRNA.
ACCESSION   XM_006711441
VERSION     XM_006711441.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006711441.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3759
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..3759
                     /gene="HHAT"
                     /gene_synonym="MART2; NNMS; SKI1; Skn"
                     /note="hedgehog acyltransferase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 11 ESTs, 119 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:55733"
                     /db_xref="HGNC:HGNC:18270"
                     /db_xref="MIM:605743"
     CDS             265..1848
                     /gene="HHAT"
                     /gene_synonym="MART2; NNMS; SKI1; Skn"
                     /codon_start=1
                     /product="protein-cysteine N-palmitoyltransferase HHAT
                     isoform X2"
                     /protein_id="XP_006711504.1"
                     /db_xref="GeneID:55733"
                     /db_xref="HGNC:HGNC:18270"
                     /db_xref="MIM:605743"
                     /translation="MRKNPPANPHQRDRWSSLRRNSQRRHREPSCQGAMLPRWELALY
                     LLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWSFWMEWGK
                     QWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHTTISFC
                     VAQFRSQLLTWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTLTVRCLYYTSFS
                     LELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQQEHDSLKASLC
                     VLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALAQVLFFYVKY
                     LVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPVGGSQ
                     HGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCIQDSLA
                     RYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLSVLG
                     FLYCYSHVGIAWAQTYATD"
     polyA_site      3759
                     /gene="HHAT"
                     /gene_synonym="MART2; NNMS; SKI1; Skn"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gcgcccgggc aaaggcgggg atctaggcgc cgggacaagt ccgcgcacgg ccctgcccac
       61 gtcctctctc cttggcttcg tccccagctt ccggaactgc tgcggggagt tgcgaactct
      121 ggtcctcttg gcagtatcgg cggtgcgcct gcctgcctgc tgtgactcca gggactctaa
      181 agttagagac ttcctttgcg ttctatcttc aggactcagt tttcttcctc tgttctgagt
      241 ctaaccttca ggtggcaggt ctttatgcgg aaaaaccctc ccgctaatcc tcaccagagg
      301 gacagatgga gttcattgag gagaaactct cagcgtaggc atcgggaacc ttcgtgccaa
      361 ggagccatgc tgccccgatg ggaactggca ctttacctac ttgcctcact aggcttccac
      421 ttctattcct tctatgaagt ttacaaagtc tccagagaac acgaagagga gctggaccag
      481 gaatttgagc tggagactga cactttattt ggaggattaa agaaggatgc gaccgacttt
      541 gagtggagct tctggatgga atgggggaag cagtggctgg tgtggcttct ccttggccac
      601 atggtagtgt ctcaaatggc cacactgctg gcaagaaagc acagaccctg gattctcatg
      661 ctctatggga tgtgggcctg ctggtgtgtg ctggggaccc ctggtgtggc tatggttttg
      721 ctccatacca ccatctcttt ctgcgtggcc cagttccggt ctcagctcct gacgtggctc
      781 tgttctctcc tcctcctctc cacactgagg ctgcagggtg tggaagaagt taagagaagg
      841 tggtacaaga cagaaaacga gtactacctg ctgcagttca cgctgaccgt tcgctgcctg
      901 tactacacca gcttcagcct ggagctctgc tggcagcagc tgcctgctgc atcgacctcc
      961 tactcctttc cctggatgct ggcctatgtc ttttattatc cagtcttaca caatgggccc
     1021 atcctcagct tctcggagtt catcaaacag atgcagcagc aggagcatga ctccctgaag
     1081 gccagcctgt gtgtcctggc cctggggctg ggccgccttc tttgctggtg gtggctggcc
     1141 gagctgatgg ctcacctgat gtacatgcat gccatctaca gcagcatccc cctcctggag
     1201 actgtctctt gttggacctt aggaggactg gcgttagccc aggtgctctt tttctacgtg
     1261 aagtacttgg tgctctttgg cgtgcctgct ctgctcatgc gcctggatgg actcactcca
     1321 cccgccctcc cccgctgcgt gagcaccatg ttcagtttca ccgggatgtg gaggtatttt
     1381 gatgttggac tgcataattt cttaatcagg tatgtgtaca ttccagtggg cgggtcccag
     1441 catggcctgc tggggacact gttttccacg gcgatgacat ttgcatttgt gagctactgg
     1501 catggcggct acgactacct ctggtgctgg gcagcgctca actggctggg agtcactgtg
     1561 gagaatggag tccggaggct ggtggagact ccctgcatcc aggacagtct ggcccgatac
     1621 ttctccccac aagctcgccg tcgattccac gctgcccttg cttcttgttc cacctcgatg
     1681 ctgatcctgt ccaacctggt atttcttggg ggcaatgagg ttgggaaaac ctactggaat
     1741 aggatcttca tacaaggctg gccttgggtg accctctctg tcctgggatt cctgtactgc
     1801 tactcccacg tgggcattgc ctgggcccag acctacgcca cggactaatg ctgttgggcc
     1861 caggccagtc cttgttgctg gcctccaagg caaatagtgc ttcaccctga cctctcactc
     1921 caggacagcc tctaagggat ttgatctgct catcttcagt tgaatgccct cactccaaga
     1981 ctggatgctg gatctcatag aaaattcaca gccagacaat cttctaatct ggagtctttg
     2041 agatcttcta ccccaactca tcattttcct attgaggaaa cgggtccagg gcagtcgtgt
     2101 gtcttaccca gctacacagg gtgacatttt ggtctagaac ctagtctcat gagccctttg
     2161 cattctttcc ccttaagcaa gaatagaatg tagtggaaat ttattgattg agacacagaa
     2221 atcctgatta gtgataggcc tgtcttctgg gcaatatttc taaaatattt gagtgacatt
     2281 gatgtttaag tgacctcctt catcacatcc tgcagtatct ccagaagcag cactagggtt
     2341 tgagtttcat gcttcagccc ctctgtagga atgagaccaa gccacagctg tcttttgaat
     2401 tacgtagtcg aagaagacgg tagcagccct gtagcattct aaggcatcta tacccaagga
     2461 gtcctgtgat ctgagcttca gcagggtgat ctacatttgg gtgcttgttt ctgagatttg
     2521 cagagaagta taacatggta gttcctctac cttacagtta atcgtttctt aataaagaag
     2581 cagaatttag aaaccacagg atagtgtacc cacagatggg tgttatcaag gccagtcatg
     2641 aggatggtgt cctggagtct tgtccaccct ctccatacaa gtctcaaaag tcatcctcct
     2701 actcagtgat tcacgtttag tggtttatat tattaaggtt tgattcaaac agagcctttt
     2761 ctgtcctgta gataatctac atgtttgtag aattattttg aatatgtttg aggaaaatgt
     2821 ttaaaatcta aatatactca cataacttga ttattcactc ctctgaaaag atgctggata
     2881 ggctaccaaa gttcccaagt ggtagataat tcagaagact tgtttgaatt tggatttttt
     2941 ttttttttgg agtggggaag ggtataaagg aggcttaaaa tttgaatcca taatatatct
     3001 aattacagga gaatttacaa catctcaagt acgtaaatta agttgtcatt gagtgaaagg
     3061 ttcacttgga cctagtgctg cctcctgttt attacatagc atggccctta tgtcttgagt
     3121 tgaggttatc atctcaatga ggctttagct cctagagtac aggaccattt tgttgattgt
     3181 ctttcttcat agcttctctg cttggcaaag agatgggagg gggccagata ctgactacct
     3241 ggggtaggca cattatgtgt taaagcaaga cagaggccag agaggggcag gtagacctgc
     3301 atagcagcag cctcagcagc tgtcttggta aaggagagag agagacatgg ggccagtaat
     3361 tccggggtgc tcagaagttt taggagggga tgagcctcag ggaggagtga gcacctaaat
     3421 gaacgcagta aaccttcatg gaccaacagt gattgaggat ttgtgggcag ccagagggag
     3481 tctgactgaa gtttacttgg aaagaaaggg cttgctaaga aaaaagggag taaaaatgat
     3541 gatagggaag tgtctaatgt atgtgcacat ataagtaata caaaagtttt gagctcttcc
     3601 aagtatacca tttatataca aacaaatagg tttattcatt cattaaacta ctttggaagc
     3661 gtcagtggat atatttgaaa gtggtaatcc tgaatctctt ttaaactatt atatgattca
     3721 taatggttct caggaattaa taaatgatta ctgtgttta
//
