LOCUS       XM_017006277            1622 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens homogentisate 1,2-dioxygenase (HGD),
            transcript variant X3, mRNA.
ACCESSION   XM_017006277
VERSION     XM_017006277.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017006277.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..1622
                     /gene="HGD"
                     /gene_synonym="AKU; HGO"
                     /note="homogentisate 1,2-dioxygenase; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 15
                     ESTs, 160 long SRA reads, 9 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 43 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:3081"
                     /db_xref="HGNC:HGNC:4892"
                     /db_xref="MIM:607474"
     CDS             500..1414
                     /gene="HGD"
                     /gene_synonym="AKU; HGO"
                     /codon_start=1
                     /product="homogentisate 1,2-dioxygenase isoform X3"
                     /protein_id="XP_016861766.1"
                     /db_xref="GeneID:3081"
                     /db_xref="HGNC:HGNC:4892"
                     /db_xref="MIM:607474"
                     /translation="MENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEICVIQRG
                     MRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVPGGY
                     TVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVL
                     TAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLP
                     GGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASR
                     CLDENYHKCWEPLKSHFTPNSRNPAEPN"
ORIGIN      
        1 cagactgttg ttggcctgat catcactcac acatccaggc ttgttacatc tccacgccac
       61 tgagtatcag ggaacctgcc ccaatattca ctacatttct ggatttggga atgagtgttc
      121 ttcagaggat cctcgctgcc caggttccct gccagaagga cagaataatc ctcaggtctg
      181 cccctacaat ctctatgctg agcagctctc aggatcggct ttcacttgtc cacggagcac
      241 caataagaga agctggctgt ataggattct accttcagtt tctcacaagc cctttgaatc
      301 cattgacgaa ggccaagtca ctcacaactg ggatgaagtt gatcctgatc ctaaccagct
      361 tagatggaaa ccatttgaga ttccaaaagc atctcagaag aaagtagact ttgtgagtgg
      421 cctgcatacc ttgtgtggag ctggagacat aaagtctaac aatgggcttg ctatccacat
      481 tttcctctgc aatacctcca tggagaacag atgcttttac aattcagatg gggacttctt
      541 gattgttccg cagaaaggga accttctcat ttacaccgag tttggcaaga tgcttgtaca
      601 gcccaatgag atctgcgtca ttcagagagg aatgcggttc agcatagatg tctttgagga
      661 gaccaggggc tacatcttgg aggtctatgg tgtccacttt gagttacctg accttggacc
      721 aattggggcc aatggcttgg ccaatcctcg tgatttcttg atacccattg cctggtatga
      781 ggatcgccaa gtaccaggtg gttacacggt cattaataaa taccagggca agctgtttgc
      841 tgccaaacag gatgtctccc cgttcaatgt tgtggcctgg cacgggaatt atacacccta
      901 caagtacaac ctgaagaatt tcatggttat caactcagtg gcctttgacc atgcagaccc
      961 atccattttc acagtattga ctgctaagtc tgtccgccct ggagtggcca ttgctgattt
     1021 tgtcatcttc ccacctcgat ggggggttgc tgataagacc ttcaggcctc cttattacca
     1081 taggaactgc atgagtgagt tcatgggact catccgaggt cactatgagg caaagcaagg
     1141 tgggttcctg ccagggggag ggagtctaca cagcacaatg accccccatg gacctgatgc
     1201 tgactgcttt gagaaggcca gcaaggtcaa gctggcacct gagaggattg ccgatggcac
     1261 catggcattt atgtttgaat catctttaag tctggcggtc acaaagtggg gactcaaggc
     1321 ctccaggtgt ttggatgaga actaccacaa gtgctgggag ccactcaaga gccacttcac
     1381 tcccaactcc aggaacccag cagaacctaa ttgagactgg aacattgcta ccataattaa
     1441 gagtagattt gtgaagattt cttcagaatc tcatgctttc tggtagtatt ggaggagggg
     1501 gttggttaaa atgaaaattc acttttcata gtcaagtaac tcagaacttt tatggaaacg
     1561 catttgcaaa gttctatggc tgtcacctta attactcaat aaacttgctg gtgttctgtg
     1621 ga
//
