LOCUS       NM_015473               7811 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens HEAT repeat containing 5A (HEATR5A), mRNA.
ACCESSION   NM_015473
VERSION     NM_015473.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7811)
  AUTHORS   Marmorale,L.J., Jin,H., Reidy,T.G., Palomino-Alonso,B.,
            Zysnarski,C.J., Jordan-Javed,F., Lahiri,S. and Duncan,M.C.
  TITLE     Fast-evolving cofactors regulate the role of HEATR5 complexes in
            intra-Golgi trafficking
  JOURNAL   J Cell Biol 223 (3) (2024)
   PUBMED   38240799
  REMARK    GeneRIF: Fast-evolving cofactors regulate the role of HEATR5
            complexes in intra-Golgi trafficking.
REFERENCE   2  (bases 1 to 7811)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 7811)
  AUTHORS   Hirst,J., Borner,G.H., Harbour,M. and Robinson,M.S.
  TITLE     The aftiphilin/p200/gamma-synergin complex
  JOURNAL   Mol Biol Cell 16 (5), 2554-2565 (2005)
   PUBMED   15758025
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL139353.3 and AL136418.4.
            
            On Nov 23, 2018 this sequence version replaced NM_015473.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660809.147693.1,
                                           SRR1803614.215701.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000543095.7/ ENSP00000437968.2
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                AL139353.3         137683-137761       c
            80-279              AL139353.3         120061-120260       c
            280-491             AL139353.3         117512-117723       c
            492-600             AL139353.3         115884-115992       c
            601-750             AL139353.3         112410-112559       c
            751-925             AL139353.3         111263-111437       c
            926-1086            AL139353.3         106056-106216       c
            1087-1342           AL139353.3         104331-104586       c
            1343-1498           AL139353.3         103631-103786       c
            1499-1749           AL139353.3         100732-100982       c
            1750-1861           AL139353.3         97678-97789         c
            1862-2014           AL139353.3         92027-92179         c
            2015-2114           AL139353.3         89021-89120         c
            2115-2224           AL139353.3         81400-81509         c
            2225-2388           AL139353.3         76105-76268         c
            2389-2564           AL139353.3         75848-76023         c
            2565-2670           AL139353.3         67823-67928         c
            2671-2861           AL139353.3         67000-67190         c
            2862-3021           AL139353.3         64959-65118         c
            3022-3211           AL139353.3         62298-62487         c
            3212-3381           AL139353.3         61107-61276         c
            3382-3520           AL139353.3         54687-54825         c
            3521-3700           AL139353.3         43374-43553         c
            3701-3940           AL139353.3         40776-41015         c
            3941-4122           AL139353.3         38710-38891         c
            4123-4191           AL139353.3         35435-35503         c
            4192-4371           AL139353.3         32981-33160         c
            4372-4594           AL136418.4         2457-2679
            4595-4843           AL136418.4         6465-6713
            4844-4971           AL136418.4         7627-7754
            4972-5119           AL136418.4         8768-8915
            5120-5392           AL136418.4         10470-10742
            5393-5617           AL136418.4         13128-13352
            5618-5772           AL136418.4         19584-19738
            5773-5986           AL136418.4         21543-21756
            5987-7811           AL136418.4         22035-23859
FEATURES             Location/Qualifiers
     source          1..7811
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q12"
     gene            1..7811
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /note="HEAT repeat containing 5A"
                     /db_xref="GeneID:25938"
                     /db_xref="HGNC:HGNC:20276"
     exon            1..79
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            80..279
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     CDS             154..6294
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /codon_start=1
                     /product="HEAT repeat-containing protein 5A"
                     /protein_id="NP_056288.2"
                     /db_xref="CCDS:CCDS45094.2"
                     /db_xref="GeneID:25938"
                     /db_xref="HGNC:HGNC:20276"
                     /translation="MELAHSLLLNEEAYNQLGEVQKAEFIFEWLRYLEKLLLATSRND
                     VREKQKTLVEQLLSLLNSSPGPPTRKLLAKNLAILYSIGDTFSVHEAIDKCNDLIRSK
                     DDSPSYLPTKLAAVVCLGSLYKKLGRILGNTFTDTVGNILKAMKSAESQGRYEIMLSL
                     QNILNGLGAAAAPCHRDVYKAARSCLTDRSMAVRCAAAKCLLELQNEAIFMWSTDLDS
                     VATLCFKSFEGSNYDVRISVSKLLGIILAKAVISKHPGTAASRQSIRRVSLEEVLELL
                     GTGFLRGSSGFLRASGDMLKGTSSVSRDVRVGVTQAYVVFVSTLGGAWLEKNFAAFFS
                     HILSLASPSHPKATQTQIDAVCCRRCVSFILRTTIGGLLGEKAQLAAVKDICQAIWKL
                     KKVMDAVMSDGNLETRLGSTDVAASQHMLVCALQELGNLIHNLGTTAAPLLQDSSTGL
                     LDSILSVILHPSISVRLAAAWCLHCIAVALPSYLTPLLDRCLERLTGHKSSPEAVTGF
                     SFAVAALLGAVKHCPLGIPHGKGKIIMTLAEDLLCSAAQNSRLSAQRTQAGWLLISAL
                     MTLGPAVVSHHLARVLLLWKCVFPASPKDLETEKSRGDSFTWQVTLEGRAGALCAIKS
                     FVSHCGDLLTEEVTQRLLPPLPCAVDLLTQLSSILKMYGSPLKTPSVVYRQRLYELLI
                     LLPPETYEGNLCAILRELAADLTAPDIQVAASTFLLPPLCHQDDLLILSPFLQETDHR
                     FIEEQLLLGNGVACGSLEYDPYSIYEKDVEGDSVPKPLPPALSVISSASKLFGVVCAH
                     VGETQRLLILEQLLDSIKHTKGARQQVVQLHVVSSVSSFLKYVAGSKGCLGPEEMKRF
                     ALTLVMGALESPNPLLRCAAAESWARLAQVVDDGAFTAGLAQVSFDKLKSARDVVTRT
                     GHSLALGSLHRYLGGISSSQHLNSCIGILYTLAQDSTSPDVQTWALHSLSLIIDSAGP
                     LYYVHVEPTLSLIIMLLLNVPPTHAEVHQSLGRCLNALITTLGPELQGNSTSISTLRT
                     SCLLGCAVMQDNPDCLVQAQAISCLQQLHMFAPRHVNLSSLVSCLCVNLCSPYLLLRR
                     AVLACLRQLVQREAAEVSEHAVMLAKDSREELTPDANIREVGLEGALLILLDKETDER
                     LCHDIKETLNYMLTSMAVEKLSLWLKLCKDVLAASADFTAVTCVDTMQEEEGDKGDDA
                     SVLTTRRDEKSHPFTNPRWATRVFAAECVCRIINQCENANSAHFDIALAQEMKKRDSR
                     NDFLVLHLADLIRMAFMAATDHSDQLRLSGLEMLLVVIRRFATVPEPEFPGHVILEQY
                     QANVGAALRPAFTSETPPDVTAKACQVCSAWIASGVVSDLNDLRRVHQLLVSSLTKIQ
                     AGKEALSHLYNESASTMEILAVLKAWAEVYIIAVQRHKNHRQPLKTTTCLEDGIRNGS
                     CSSDGLLDLVYADLGTLSRLWLAALQDFALLTLPSEFASQLPAEGGAFYTAETSENAK
                     LHYYNSWALILHATALWLTSTGFVVADPDEGASNLSRPVTPTSMCQGSSSGATIKSPE
                     DVYTDRFHLILGISVEFLCSLRSDATMESITACLHALQALLDVPWPRSKIGSDQDLGI
                     ELLNVLHRVILTRESPSIQLASLEVVRQIICAAQEHVKEKRRSAEVDDGAAEKETLPE
                     FGEGKDTGGLVPGKSLVFATLELCVCILVRQLPELNPKLTGSPGVKATKPQILLEDGS
                     RLVSAALVILSELPAVCSPEGSISILPTILYLTIGVLRETAVKLPGGQLSSTVAASLQ
                     ALKGILSSPMARAEKSRTAWTDLLRSALTTILDCWDPVDETHQELDEVSLLTAITVFI
                     LSTSPEVTTIPCLQKRCIDKFKATLEIKDPVVQIKTYQLLHSIFQYPNPAVSYPYIYS
                     LASCIMEKLQEIDKRKPENTAELEIFQEGIKVLETLVTVAEEHHRAQLVACLLPILIS
                     FLLDENSLGSATSIMRNLHDFALQNLMQIGPQYSSVFKSLVASSPALKARLEAAIKGN
                     QESVKVKIPTSKYTKSPGKNSSIQLKTSFL"
     exon            280..491
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            492..600
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            601..750
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            751..925
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            926..1086
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1342
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            1343..1498
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            1499..1749
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1861
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            1862..2014
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2015..2114
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2224
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2225..2388
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2389..2564
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2565..2670
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2671..2861
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            2862..3021
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3022..3211
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3212..3381
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3382..3520
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3521..3700
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3701..3940
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            3941..4122
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4123..4191
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4192..4371
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4372..4594
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4595..4843
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4844..4971
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            4972..5119
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            5120..5392
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            5393..5617
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            5618..5772
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            5773..5986
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     exon            5987..7811
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7789..7794
                     /regulatory_class="polyA_signal_sequence"
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /note="hexamer: AATAAA"
     polyA_site      7811
                     /gene="HEATR5A"
                     /gene_synonym="C14orf125; p200b"
                     /note="major polyA site"
ORIGIN      
        1 agactctgct agggttagca gagcagccgg taacgttgct ggaccgggac gcacgctcag
       61 ctgaggagga cccccaaaga tttttattgt taggtatatt gaccaaagtt taacgagaag
      121 aactgtgatc agctgggagg attgctgcaa ggaatggaat tagctcatag cttactgctg
      181 aatgaagaag catacaatca actaggtgaa gttcagaagg cagagtttat ttttgagtgg
      241 ttgagatact tggagaagct cttgttggca accagcagga atgatgtaag ggagaaacag
      301 aagactcttg ttgaacagct cctgtctttg ttgaacagct ccccagggcc tcctacccgc
      361 aaactgcttg ctaagaatct agccatactt tatagtattg gagacacatt ctccgttcat
      421 gaagcaatcg ataaatgtaa tgatcttatt cgtagcaaag atgattctcc aagttatctt
      481 cccactaagc ttgctgctgt ggtatgtttg ggttccttgt acaagaagtt gggtagaata
      541 ctgggtaaca cctttactga tacagtgggg aatattctta aagctatgaa gagtgcagag
      601 tctcaaggcc gatatgagat tatgctaagt ctgcaaaata tattgaatgg actaggagct
      661 gccgctgcac cttgtcacag ggatgtttat aaagctgcta gatcctgctt gacagataga
      721 tccatggctg ttcgttgtgc tgctgcaaag tgtctccttg aacttcagaa tgaagccatc
      781 tttatgtgga gtacggacct ggacagtgtg gccacactgt gttttaagtc ctttgaaggt
      841 tccaattatg atgtgcggat ttctgtttca aagttactag gcataatatt agctaaagct
      901 gtaatttcta aacatccagg aacagcagcc tcacgtcaaa gcattcgcag agtatctttg
      961 gaggaagttc tggaattact aggaacaggg tttctacgtg ggagttcagg attccttcga
     1021 gccagtggag atatgctgaa aggaaccagt tcagtcagta gggatgttcg agttggagtt
     1081 actcaggctt atgtggtatt tgtttcaaca ctaggaggag cttggctaga gaaaaatttt
     1141 gctgcctttt tttctcatat cctaagcctt gcgtcaccgt cacaccctaa agccacccaa
     1201 actcagatcg atgccgtctg ctgtcgccgt tgtgtttcat ttattcttcg aactactata
     1261 ggtggtcttc ttggagaaaa ggctcagctt gctgctgtaa aggatatttg ccaggccatc
     1321 tggaagctaa agaaagttat ggatgccgta atgagtgatg gtaatttgga aacccggctt
     1381 ggttccacag atgtagccgc tagccaacat atgctggttt gtgctttaca agaacttgga
     1441 aatctcatac acaatcttgg caccacagcg gcacctttgc tacaggattc aagtacaggt
     1501 ctccttgaca gtatcttgtc agttattctt catcctagca tttctgttcg actagcagca
     1561 gcttggtgtt tacactgcat tgccgtggca ttaccctcct acctaacacc actcttggat
     1621 cgttgccttg aacggcttac tggacataag tcttcacctg aagcagtgac tggcttcagt
     1681 tttgctgtag cagctttgtt gggagcagta aaacattgtc ctttaggaat tcctcatgga
     1741 aaaggcaaga ttattatgac attagcagag gatttgctgt gttctgctgc tcaaaacagt
     1801 cgcctttcag ctcagcgcac acaagctgga tggttgctga tttctgctct gatgacatta
     1861 ggtcctgcag ttgttagcca tcaccttgct cgagttctgc tgttgtggaa gtgtgtcttt
     1921 ccagcatctc ctaaagatct agaaacagaa aagagccgag gagattcgtt tacatggcag
     1981 gtgaccctgg aaggacgagc tggtgcactg tgtgctatca agagctttgt ttcccactgt
     2041 ggtgatcttc ttactgagga agtaactcag cgtcttcttc caccacttcc ttgtgctgtg
     2101 gatttgctaa ctcagctttc ttcaatacta aaaatgtatg gaagtccttt gaaaacaccg
     2161 tcagtggttt atagacaaag actttatgaa ctgttgattt tattacctcc tgagacctat
     2221 gaaggaaacc tctgtgctat cctcagagag ctggctgctg acttgactgc ccctgatatt
     2281 caggtggcag catctacatt tttacttcca cccctctgtc atcaggatga tcttttgata
     2341 ctaagtcctt tcctacaaga gactgaccat agatttattg aagaacagct cctgcttggt
     2401 aatggtgttg cttgcggaag tcttgaatat gacccttatt cgatttatga gaaagatgta
     2461 gagggagatt cagtgcctaa gcccttacct ccagcactat cagttattag ttctgcatcc
     2521 aagctctttg gggttgtatg cgctcatgtg ggagaaactc aaaggcttct tatattggaa
     2581 cagcttttgg acagtataaa gcacacaaaa ggagctcgtc agcaagtggt tcagttacat
     2641 gttgtttctt cagtttctag tttcttgaag tacgtggctg gctccaaggg atgtttaggt
     2701 ccagaagaaa tgaaaagatt tgccttaaca ttagttatgg gagccctaga aagccccaac
     2761 cccttgctga gatgtgcagc tgcagagtca tgggctagat tagcccaagt ggtagatgat
     2821 ggagctttta ctgctggatt agctcaagtt agctttgaca aattgaaatc agcaagggat
     2881 gtggttacca gaacaggaca ctcattggcc ttggggtccc tacataggta tttaggagga
     2941 ataagttctt ctcaacacct aaattcttgt attggaatcc tttatacttt ggcgcaggac
     3001 agcacttctc ctgatgtgca gacctgggca ttacattctc tatcattgat cattgattct
     3061 gctggcccac tctattatgt gcatgtggaa cctacccttt ctcttattat aatgttgttg
     3121 ttaaatgtgc ctcctactca tgctgaagtt caccaaagcc ttggtcgctg tttgaatgcc
     3181 cttattacca cgttaggtcc agagctacaa ggtaacagta cttcaatttc taccttaagg
     3241 acttcctgtc tactgggttg tgcagtaatg caagataacc cagactgcct tgttcaagct
     3301 caggccatct cttgccttca gcagcttcat atgtttgctc cacgacatgt caacttgtct
     3361 agcctggtta gctgcctctg tgtgaatctt tgtagcccct acttgttact gagaagagca
     3421 gtactggctt gcttacgtca gcttgtacaa agagaagcag ctgaagtttc agaacatgct
     3481 gttatgcttg ctaaggatag cagagaagag ttgactccag atgctaacat cagagaagtt
     3541 ggccttgagg gggcattgtt gatcttacta gacaaggaga cagatgagag attatgccat
     3601 gatatcaaag agactttaaa ttatatgctt acatctatgg cagtggaaaa actctccctg
     3661 tggttaaagc tttgtaaaga tgtacttgct gcatcagctg attttacagc tgtaacttgt
     3721 gtggatacaa tgcaagaaga agaaggagat aaaggggatg atgcctcagt cctgaccacc
     3781 agacgtgatg aaaaatccca tccttttacc aatccccgat gggctactag agtctttgct
     3841 gctgaatgtg tctgtaggat aattaaccaa tgtgagaatg ctaacagtgc acattttgac
     3901 attgctttag cacaagaaat gaaaaaaaga gattcaagaa atgacttttt ggtactgcat
     3961 cttgctgact taattcgcat ggcttttatg gctgccacag atcacagtga ccagctccgt
     4021 ctttctggcc ttgaaatgct gttagttgtt attcggcgat ttgcaactgt tccagaacca
     4081 gagtttccag gtcatgtgat tctggaacag tatcaagcca atgtaggagc agcgcttaga
     4141 ccagccttca cttcagagac accacctgat gtcactgcca aagcatgtca ggtttgcagt
     4201 gcctggatag caagtggagt tgtaagtgac cttaatgatc tccgaagagt tcatcagttg
     4261 cttgtttcat cgttaactaa aatacaggct ggaaaagaag ctctaagtca cttatataat
     4321 gaaagtgctt ctaccatgga gatcttagct gtgcttaaag cctgggcaga ggtctacata
     4381 attgctgtgc aaagacataa aaaccacaga caacctttga agactaccac ctgtttagaa
     4441 gacggtatca gaaatggatc atgttcatca gatggactgc ttgacttagt ctatgcagat
     4501 cttggcacac taagcagact ctggcttgct gcacttcagg attttgctct tttaactttg
     4561 ccttcagaat ttgcctccca acttcctgct gaaggtggtg ctttctacac agcagagact
     4621 agtgaaaatg caaaattgca ttattacaac tcctgggcac ttatcctcca tgctacagca
     4681 ttgtggctta caagcacggg ttttgttgtt gctgacccag atgaaggagc atctaatctc
     4741 tccaggcctg taacaccaac ttccatgtgt cagggttcat catctggggc taccataaag
     4801 tcccctgagg atgtctacac tgatagattc catcttattt taggaatcag cgtggaattt
     4861 ctatgttcct tacgttcaga tgcaaccatg gaaagcataa ctgcttgttt acatgcattg
     4921 caagcacttc tagatgtacc ttggcccaga tcaaaaattg gcagtgatca ggacttgggt
     4981 atagaattgc tgaatgttct acatcgagta attttaacca gagaatcacc ttccattcag
     5041 ttggcttcac ttgaagtggt aaggcagatt atctgtgctg ctcaagaaca tgtgaaggaa
     5101 aaaagacgaa gtgcagaagt tgatgatggg gctgctgaaa aggaaactct gccagagttt
     5161 ggagagggaa aggacaccgg aggacttgtg cctggaaagt ctttggtctt tgcaacactg
     5221 gaattgtgtg tatgcattct agttagacag ctcccagaat taaaccctaa attgacaggt
     5281 agcccaggag taaaagctac gaagccacag atactattag aagatggaag tagattggtt
     5341 tcagctgcat tggttatcct ttccgaactt cctgcagtgt gctctcctga aggaagcatc
     5401 tcaattctcc ctactatatt gtacctcaca atcggggtcc tcagagagac tgctgtgaag
     5461 ttacctgggg gccagttatc ttcgacagtt gcagcttccc tacaggctct aaaaggaata
     5521 ttatcttctc ccatggcccg ggcagaaaag agccgtactg cttggactga ccttctccga
     5581 agtgccttaa caacaattct tgactgttgg gatccagttg atgaaacaca ccaagaactt
     5641 gatgaagtca gtctacttac tgctatcaca gtgtttattt tgtctaccag tccagaagta
     5701 actaccatcc catgccttca gaagcgctgt attgataaat ttaaagctac tcttgagata
     5761 aaagatcctg tggtacaaat caagacctac cagctcctac attccatctt tcagtatcca
     5821 aatccagctg tttcctaccc atacatttac tctttagcat cctgtatcat ggaaaaactg
     5881 caggaaatag acaagagaaa acctgaaaac actgctgagc ttgagatctt ccaagaaggc
     5941 ataaaggtct tagaaacact ggttactgtt gctgaagaac accatcgcgc tcagctggtg
     6001 gcctgtcttt tgcccatcct catttccttc cttttggatg aaaattctct gggatcagca
     6061 acttccataa tgagaaattt acatgacttt gctctacaaa atctcatgca aattggacct
     6121 cagtattcat ctgtttttaa aagtttagtg gcttcttctc cagccctaaa agcccgcctt
     6181 gaggctgcta taaagggcaa tcaggaaagt gtcaaagtca agataccaac atctaaatat
     6241 actaagagtc ctggaaaaaa ctcaagcatc caattaaaga ccagtttcct ctgatttttt
     6301 ttttggaata gtaagcacct taatataata aatacttgat cattgccttt ggtgacaaaa
     6361 gggacattgt agacacaagt gcccttagag gtctagttga ttgttttacc ttaaatagct
     6421 gtgactcttc aaagtaacag catacttaac atttttgtgt gtgtgcgtgg ggtttgtgtt
     6481 ttgttttgtt ttgtttttct atttaaaaag acaatggagc taacttgcca ggaattttaa
     6541 gaaagtgcta aagaactaaa cttactaaac aatccactgc tttaaaaatg aaatgaattt
     6601 cttctaacag tccatacata tgtggtatac ttaatactgt gacagatata aatatgactc
     6661 tagtgtaaat tatctgcact aatattgtat cccaattgct gatttaaaat tctgctttgg
     6721 cccggcacag tggctcatcc ctgtaattcc agcactttgg aaggccaagg cgggcggatc
     6781 acgaagtcgg gagtttgaga ccagcctgac caacatggtg aaaccccgtc tctactaaaa
     6841 atacaaaaat tagccgggtg tggtggcaca cacctgtaat cccagctact caggaggccg
     6901 aggcaggaaa atcgcttgaa cctggcaggc agaggttgca gtgagccaag attgtgccac
     6961 tgcactccag cctgggcgac agagtgagac tccatctaaa aaaaaaaaaa aaaaattctg
     7021 ccttattcag taattgtatt aaactttctc tgatttctcc aagaagataa aatgattgga
     7081 gagctattta ggaaacctgg tctaggatta tccagtatac aatagtacaa attacttaca
     7141 gccttacagt gcaacataag atttggtgtc tatatcatgg ttttccacca tcttttggtt
     7201 tagtttatat tgggttcaga aattgagtct tactcatttt aaatagaata agccatttcc
     7261 actatttttc aaatggattt ttctgtttac ctctgttctt accaattttg ttcattttca
     7321 tttgtggcaa acatttgtat caatgagttt taacctaggt tcatatctac attgtattta
     7381 gatcaactat gggtttatat aaatgccaaa tttagtacaa caaatttagg tcatcaggtg
     7441 aatacaagta ttttttttaa caggaaacat tttattatag aaaaaagatt aatgataaag
     7501 tcatattggt tgaaaaatat tttttaactg tgttcatgat tgttgattct ccttctactt
     7561 cagtgttata ctgtgtgaat caagcactgt gtcaaaacag agcatttccc tcttaaaaat
     7621 tacaaaccga agtgatagaa gcatgtcaga attgagaaga cattttgaag caagaacaat
     7681 gtgatgtacc tattttatta tgtttgtata taaatactat tgtaaattgt tcagagtgaa
     7741 aacatttgac aaactctaac actacaatca ttttttctaa attacataaa taaagctaat
     7801 tttcattatc a
//
