LOCUS       NM_138574               2101 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens HDGF like 1 (HDGFL1), mRNA.
ACCESSION   NM_138574
VERSION     NM_138574.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Aschebrook-Kilfoy,B., Argos,M., Pierce,B.L., Tong,L., Jasmine,F.,
            Roy,S., Parvez,F., Ahmed,A., Islam,T., Kibriya,M.G. and Ahsan,H.
  TITLE     Genome-wide association study of parity in Bangladeshi women
  JOURNAL   PLoS One 10 (3), e0118488 (2015)
   PUBMED   25742292
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  AUTHORS   Li,J., Lange,L.A., Duan,Q., Lu,Y., Singleton,A.B., Zonderman,A.B.,
            Evans,M.K., Li,Y., Taylor,H.A., Willis,M.S., Nalls,M., Wilson,J.G.
            and Lange,E.M.
  TITLE     Genome-wide admixture and association study of serum iron,
            ferritin, transferrin saturation and total iron binding capacity in
            African Americans
  JOURNAL   Hum Mol Genet 24 (2), 572-581 (2015)
   PUBMED   25224454
REFERENCE   3  (bases 1 to 2101)
  AUTHORS   Ansermet,F., Lespinasse,J., Gimelli,S., Bena,F. and
            Paoloni-Giacobino,A.
  TITLE     Mild intellectual disability associated with a progeny of
            father-daughter incest: genetic and environmental considerations
  JOURNAL   J Child Sex Abus 19 (3), 337-344 (2010)
   PUBMED   20509080
  REMARK    GeneRIF: The segment encompassed only one UCSC (University of
            California-Santa Cruz genome bioinformatics database) gene: HDGFL1
            (Homo sapiens hepatoma derived growth factor like 1, GB #AL033539).
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL033539.18.
            
            On May 17, 2019 this sequence version replaced NM_138574.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: DB478901.2, CD557735.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000510882.4/ ENSP00000442129.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2101              AL033539.18        11686-13786
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p22.3"
     gene            1..2101
                     /gene="HDGFL1"
                     /gene_synonym="dJ309H15.1; Hdgfrp1; HRP-1; PWWP1"
                     /note="HDGF like 1"
                     /db_xref="GeneID:154150"
                     /db_xref="HGNC:HGNC:21095"
     exon            1..2101
                     /gene="HDGFL1"
                     /gene_synonym="dJ309H15.1; Hdgfrp1; HRP-1; PWWP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..766
                     /gene="HDGFL1"
                     /gene_synonym="dJ309H15.1; Hdgfrp1; HRP-1; PWWP1"
                     /note="PWWP domain containing 1; HDGF (hepatoma-derived
                     growth factor) like; hepatoma derived growth factor-like
                     1; PWWP domain-containing protein 1; testicular tissue
                     protein Li 84"
                     /codon_start=1
                     /product="hepatoma-derived growth factor-like protein 1"
                     /protein_id="NP_612641.2"
                     /db_xref="CCDS:CCDS34347.1"
                     /db_xref="GeneID:154150"
                     /db_xref="HGNC:HGNC:21095"
                     /translation="MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHMTQPNRYQVFFFG
                     THETAFLSPKRLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSG
                     DGPWPEPEAAEGDEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRP
                     KEAAPDQEEEAEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQ
                     PEEEELREEEVADEEASQEWHAEAPGGGDRDSL"
     regulatory      2077..2082
                     /regulatory_class="polyA_signal_sequence"
                     /gene="HDGFL1"
                     /gene_synonym="dJ309H15.1; Hdgfrp1; HRP-1; PWWP1"
                     /note="hexamer: AATAAA"
     polyA_site      2101
                     /gene="HDGFL1"
                     /gene_synonym="dJ309H15.1; Hdgfrp1; HRP-1; PWWP1"
                     /note="major polyA site"
ORIGIN      
        1 agaaccagct atgtcggcct acggcatgcc catgtacaag agcggggacc tggtgtttgc
       61 caagttaaag ggctatgccc actggccggc gaggatagag cacatgaccc agcccaaccg
      121 ctaccaggtg tttttcttcg ggacccacga gacggccttc ctgagtccca aacgcctgtt
      181 cccgtacaag gagtgcaagg agaagttcgg caagcccaac aagaggcgcg gcttcagcgc
      241 ggggctgtgg gaaatcgaga acaaccccac ggtccaggcc tccgactgcc cattagcctc
      301 agagaagggc agcggagacg ggccttggcc ggagcccgag gccgcagagg gcgacgagga
      361 caagccgacc cacgctggtg gcggcggcga cgaattgggg aagccggacg acgacaagcc
      421 cactgaggag gagaaggggc cgctgaagag gagcgcgggg gacccgccgg aggacgcccc
      481 caaacgaccc aaggaggcag cccccgacca agaggaggag gcggaggcgg agagggcggc
      541 ggaagcggag agggcggcgg cggcggcggc ggcgacggcc gtcgacgagg agagtccgtt
      601 cctcgtggcg gtggagaacg gcagcgcccc tagcgagccg ggcctggtct gcgagccgcc
      661 tcagccagag gaggaggagc tccgggagga agaagtcgcg gacgaggagg cctcccagga
      721 gtggcatgcc gaggcaccgg gcggcggaga tcgcgacagc ctgtagttac cagcgtttcc
      781 agaagagccc ctgccccgtt cctgctgcgg cctggccgtt cttggggaat ctgaccacgg
      841 cgtgcaaact gggactgcct ttccctctcc tcagcccgtc ctcctccaac ccgcgctcct
      901 ttgccctgcc gggccccagg atggcaggcc acctgactct cacctctgtg cccccacgcc
      961 tctgtgatct gagtcagggc ctcagttccc tccctgggat aaagtgaggc caccatccca
     1021 gcttccggct ccctcttctc ccccctctac ccgccacccc accccacccc acccccgccc
     1081 actcgttgcc tgattccgtt tccgacttgg ggttcaggca ggctgttttc acctctagac
     1141 acccctctcc acccctcctg cttccccagg cattatgaac ctctgcttag gaatatgggt
     1201 aggagtgaaa ggcctggcag ataaagagca gagggcactt gcagggcctg ggatgagcag
     1261 tcttcaagct gtggtagtta gcgggcagga gagcgacatc ttcctgagct cctgtccatg
     1321 cctgccatac ctgccagctt cagacattta gggaaaaggg gcagcatgtg gggaatgccc
     1381 cccgccttcc acaaatcctt ttgctgaccc aggaagttct gggagttgcc gtttttcatc
     1441 aaaacgtttg ggggcttcca agttgtttgt gagatctgaa aacttaactt tgcccaatat
     1501 cctggttggg gaccgtgaga aatatctgtc ccatttagat ctctggggcc actgatggga
     1561 tgccctggga agatccttgg ctgccgcttt ctctccccac agcctcaagg ccaccctacc
     1621 gtcatatata tcactcaggc gtagaagaaa agacacatat tttataaaat ctttttaata
     1681 aaaggaagtt ccaagaagaa tttttaagaa ctacctctag gtgtgcctcc acgctggccc
     1741 tagctttccc attgctgttc cattgctgag acaaactgga aggctccctt tctgtttgaa
     1801 gttttatgac ttgtagtcag gctttgctgt tcgtcacagt gtcattttcc attcaggtac
     1861 catcacctgg tcccatcaac aggtctagta tgtagctcac tgataacaga ggaagatgtg
     1921 tctcctccca ccctcttcct aatggtcatt atgcctttct ccatctattg tctctttcac
     1981 cccttcccct ctcccttggg ctctgatgaa aaattgttga ctgcagtttc ggaagtttga
     2041 tctgagaacc aaccatagaa tgtttcagtt ctaggaaata aaaccagttg attaaagcaa
     2101 a
//
