LOCUS       NM_001371919            1110 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens H3.Y histone 2 (H3Y2), mRNA.
ACCESSION   NM_001371919
VERSION     NM_001371919.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1110)
  AUTHORS   Seal,R.L., Denny,P., Bruford,E.A., Gribkova,A.K., Landsman,D.,
            Marzluff,W.F., McAndrews,M., Panchenko,A.R., Shaytan,A.K. and
            Talbert,P.B.
  TITLE     A standardized nomenclature for mammalian histone genes
  JOURNAL   Epigenetics Chromatin 15 (1), 34 (2022)
   PUBMED   36180920
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1110)
  AUTHORS   Resnick,R., Wong,C.J., Hamm,D.C., Bennett,S.R., Skene,P.J.,
            Hake,S.B., Henikoff,S., van der Maarel,S.M. and Tapscott,S.J.
  TITLE     DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4 Target Genes
            for Expression
  JOURNAL   Cell Rep 29 (7), 1812-1820 (2019)
   PUBMED   31722199
  REMARK    GeneRIF: DUX4-Induced Histone Variants H3.X and H3.Y Mark DUX4
            Target Genes for Expression.
REFERENCE   3  (bases 1 to 1110)
  AUTHORS   Sadakierska-Chudy,A., Kostrzewa,R.M. and Filip,M.
  TITLE     A comprehensive view of the epigenetic landscape part I: DNA
            methylation, passive and active DNA demethylation pathways and
            histone variants
  JOURNAL   Neurotox Res 27 (1), 84-97 (2015)
   PUBMED   25362550
  REMARK    Review article
REFERENCE   4  (bases 1 to 1110)
  AUTHORS   Szenker,E., Ray-Gallet,D. and Almouzni,G.
  TITLE     The double face of the histone variant H3.3
  JOURNAL   Cell Res 21 (3), 421-434 (2011)
   PUBMED   21263457
  REMARK    Review article
REFERENCE   5  (bases 1 to 1110)
  AUTHORS   Wiedemann,S.M., Mildner,S.N., Bonisch,C., Israel,L., Maiser,A.,
            Matheisl,S., Straub,T., Merkl,R., Leonhardt,H., Kremmer,E.,
            Schermelleh,L. and Hake,S.B.
  TITLE     Identification and characterization of two novel primate-specific
            histone H3 variants, H3.X and H3.Y
  JOURNAL   J Cell Biol 190 (5), 777-791 (2010)
   PUBMED   20819935
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC106774.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000600799.3/ ENSP00000497053.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1110              AC106774.2         126377-127486       c
FEATURES             Location/Qualifiers
     source          1..1110
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5p15.1"
     gene            1..1110
                     /gene="H3Y2"
                     /gene_synonym="H3.X; H3.Y.2"
                     /note="H3.Y histone 2"
                     /db_xref="GeneID:340096"
                     /db_xref="HGNC:HGNC:43734"
     exon            1..1110
                     /gene="H3Y2"
                     /gene_synonym="H3.X; H3.Y.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             309..752
                     /gene="H3Y2"
                     /gene_synonym="H3.X; H3.Y.2"
                     /note="H3 histone, family 3B (H3.3B) pseudogene; histone
                     cluster 2, H3d pseudogene; Putative histone H3.X; histone
                     H3.Y2"
                     /codon_start=1
                     /product="histone H3.X"
                     /protein_id="NP_001358848.1"
                     /db_xref="CCDS:CCDS93687.1"
                     /db_xref="GeneID:340096"
                     /db_xref="HGNC:HGNC:43734"
                     /translation="MARTKQTARKATAWQAPRKPLATKAARKRASPTGGIKKPHRYKP
                     GTLALREIRKYQKSTQLLLRKLPFQRLVREIAQAISPDLRFQSAAIGALQEASEAYLV
                     QLFEDTNLCAIHARRVTIMPRDMQLARRLRGEGAGEPTLLGNLAL"
ORIGIN      
        1 agagatctcc agtcagaaac agactgcctg cgagggagac tcctggctgc tgctgggtag
       61 accaaggaaa cccaagacct tccgggaaga ctaagcagcc cggcctccga cccacagacc
      121 tgagagctgg taagtgtggg gttgggttgg caggggttaa gtgtgtggga gagtcctgcg
      181 catggatctc aactcacagg ctctctgaat cctgtccaca gcaccactgc ccttgttttc
      241 tgacgccagt actgcctgca gcaggccagg ctcagcctca gagaggagag agcacaaggc
      301 cccacaacat ggcgcgcacc aagcagaccg cccgcaaagc caccgcctgg caggccccca
      361 ggaagcccct ggccaccaaa gccgccagaa aaagggcgtc gcctacagga gggatcaaga
      421 agcctcaccg ctacaagcct ggcaccctgg cgctgcggga aatcagaaag taccagaagt
      481 ccacgcagct gctcctgcgc aagctgccct tccagcgtct ggtgcgtgag atcgcccagg
      541 ccatcagccc ggacctgcgc ttccagagcg cggccattgg cgccctgcag gaggccagcg
      601 aggcctacct ggtgcaactc tttgaagaca ccaacctgtg tgccatccat gccaggcgcg
      661 tcacaattat gccccgagac atgcagctgg cccgccgcct ccgtggagag ggtgccggag
      721 agcccacgct cctgggaaac cttgcactct agaggacttc ttttctgttt gcttgtgttt
      781 tcttttttct cttcccccgt aactggtagt tctgatgtga gaagttttgt tctgttttgg
      841 tttcttttcc ctccgggggt ccaaaggtag ctaagcataa gattgccagt ggaaacgcag
      901 gcagaaatca ggtggcagtt gtgtttgtgt gtgcttgtta gtaaacgtct catctacttt
      961 gaggctccca aggtactagt gtcaagtgga aatgtctctg tgagcgagtt tcagttcaac
     1021 tctataaaat tataaagaaa tcttattttt ttttctttac tatgtctgca tacgggttct
     1081 gtaaacaaaa taaatttctt attaatctga
//
