LOCUS       NM_001401340             570 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens H2B.N variant histone 1 (H2BN1), mRNA.
ACCESSION   NM_001401340
VERSION     NM_001401340.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Raman,P., Rominger,M.C., Young,J.M., Molaro,A., Tsukiyama,T. and
            Malik,H.S.
  TITLE     Novel Classes and Evolutionary Turnover of Histone H2B Variants in
            the Mammalian Germline
  JOURNAL   Mol Biol Evol 39 (2) (2022)
   PUBMED   35099534
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084809.17.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000704639.1/ ENSP00000515970.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-174               AC084809.17        51624-51797
            175-570             AC084809.17        62382-62777
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q11.2"
     gene            1..570
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /note="H2B.N variant histone 1"
                     /db_xref="GeneID:124188214"
                     /db_xref="HGNC:HGNC:56200"
     CDS             1..357
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /codon_start=1
                     /product="histone H2A.N"
                     /protein_id="NP_001388269.1"
                     /db_xref="CCDS:CCDS92289.1"
                     /db_xref="GeneID:124188214"
                     /db_xref="HGNC:HGNC:56200"
                     /translation="MYFICLNDLRFPKNKTELYFPVKKKHEWANSATGKKRRWRKKRR
                     KEAYFSYMGKILKQIHPDFSGRSWVLYALGALNAWQLEWVSLEAFRLSFYNHRRAITG
                     REILGAVKQRSSQKSF"
     exon            1..174
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /inference="alignment:Splign:2.1.0"
     exon            175..570
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /inference="alignment:Splign:2.1.0"
     regulatory      542..547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /note="hexamer: AATAAA"
     polyA_site      570
                     /gene="H2BN1"
                     /gene_synonym="H2B.N"
                     /note="major polyA site"
ORIGIN      
        1 atgtatttca tttgcttaaa tgacctaaga ttccctaaga acaagactga gctttatttc
       61 ccagtcaaaa agaagcatga gtgggccaac tcagccactg ggaagaagag gaggtggaga
      121 aagaagagga ggaaggaagc ctattttagt tacatgggga aaatcctaaa gcaaatccac
      181 cctgatttca gcgggcgttc ctgggtcttg tatgcactag gtgccctcaa tgcttggcaa
      241 ctggaatggg ttagcctgga ggcatttagg ctgtccttct acaaccacag aagagccatc
      301 actggcagag agatccttgg cgcagttaag cagagatctt ctcagaagag cttttgaata
      361 aatgaagttg ttcagaatgg ccttgttaaa atgactcact tgtcaaaaaa ctagatgtgt
      421 tggaaggctg ggttggaaga caagatgtct gagaagctgt cctgctgcat gaggagtttc
      481 attgctacac acctagtctc tgggtcctgt gtttttggcc tccagcttac ttcgtgaaca
      541 taataaagga aaggcatttt ctcttgtgca
//
