LOCUS       NM_001395555             633 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens H2A.L variant histone 3 (H2AL3), mRNA.
ACCESSION   NM_001395555
VERSION     NM_001395555.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 633)
  AUTHORS   Seal,R.L., Denny,P., Bruford,E.A., Gribkova,A.K., Landsman,D.,
            Marzluff,W.F., McAndrews,M., Panchenko,A.R., Shaytan,A.K. and
            Talbert,P.B.
  TITLE     A standardized nomenclature for mammalian histone genes
  JOURNAL   Epigenetics Chromatin 15 (1), 34 (2022)
   PUBMED   36180920
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 633)
  AUTHORS   Molaro,A., Young,J.M. and Malik,H.S.
  TITLE     Evolutionary origins and diversification of testis-specific short
            histone H2A variants in mammals
  JOURNAL   Genome Res 28 (4), 460-473 (2018)
   PUBMED   29549088
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL121578.1.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000448797.3/ ENSP00000498087.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-633               AL121578.1         160592-161224
FEATURES             Location/Qualifiers
     source          1..633
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.4"
     gene            1..633
                     /gene="H2AL3"
                     /gene_synonym="H2A.L.3; H2AL1RP"
                     /note="H2A.L variant histone 3"
                     /db_xref="GeneID:115482686"
                     /db_xref="HGNC:HGNC:53960"
     exon            1..633
                     /gene="H2AL3"
                     /gene_synonym="H2A.L.3; H2AL1RP"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..519
                     /gene="H2AL3"
                     /gene_synonym="H2A.L.3; H2AL1RP"
                     /note="H2A.L variant histone R, pseudogene"
                     /codon_start=1
                     /product="histone H2A-like 3"
                     /protein_id="NP_001382484.1"
                     /db_xref="CCDS:CCDS94587.1"
                     /db_xref="GeneID:115482686"
                     /db_xref="HGNC:HGNC:53960"
                     /translation="MAGNKMFCRPRRQRLSHSRRAELQFPVSHLERCLRESQHARHLS
                     STTPVFLAGVLEYLTANILEKVGKEVKNSCRLCITPEHVKRALQKDEQLRWILELEDD
                     THSQVEEMPQSEEEEEEEEEKEEEMVVLVVMGGRRRRRRRRRRKDS"
     regulatory      615..620
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2AL3"
                     /gene_synonym="H2A.L.3; H2AL1RP"
                     /note="hexamer: ATTAAA"
     polyA_site      633
                     /gene="H2AL3"
                     /gene_synonym="H2A.L.3; H2AL1RP"
                     /note="major polyA site"
ORIGIN      
        1 tggtaccttg agaggctcag gccagcagga aaatcaagct gtgccaattg gggcaaaacc
       61 cagcaattcc tcatggctgg aaacaaaatg ttctgtaggc ctaggagaca acgcctttcc
      121 cattccagaa gagcagagct gcagtttcct gtcagccact tggaacgctg cctgcgagaa
      181 agtcagcatg cccggcacct gagctcaacc acacctgttt tcctggctgg tgttctcgag
      241 tatctgacag ccaacatcct ggaaaaggtg ggcaaggagg tcaagaacag ctgcaggctg
      301 tgcatcaccc cagaacacgt gaagagggca ctgcaaaagg atgagcagct cagatggatc
      361 ttggagttgg aagatgacac ccactctcaa gtagaagaaa tgccccaatc tgaggaggaa
      421 gaggaggagg aggaggagaa ggaggaggag atggtggtgc tggtggtgat ggggggaagg
      481 aggaggagga ggagaagaag gaggaggaag gattcctgag tttcggagcc atgcgggact
      541 tcatcagcaa cctcctccag atgccaaaat tcccatagat gaaagacccc aggttgcttc
      601 catctgccca agctattaaa ctgtgtaaat gca
//
