LOCUS       NM_004130               5996 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens glycogenin 1 (GYG1), transcript variant 1, mRNA.
ACCESSION   NM_004130
VERSION     NM_004130.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5996)
  AUTHORS   Fastman,N.M., Liu,Y., Ramanan,V., Merritt,H., Ambing,E.,
            DePaoli-Roach,A.A., Roach,P.J., Hurley,T.D., Mellem,K.T.,
            Ullman,J.C., Green,E., Morgans,D. Jr. and Tzitzilonis,C.
  TITLE     The structural mechanism of human glycogen synthesis by the
            GYS1-GYG1 complex
  JOURNAL   Cell Rep 40 (1), 111041 (2022)
   PUBMED   35793618
  REMARK    GeneRIF: The structural mechanism of human glycogen synthesis by
            the GYS1-GYG1 complex.
REFERENCE   2  (bases 1 to 5996)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 5996)
  AUTHORS   Munoz Sosa,C.J., Issoglio,F.M. and Carrizo,M.E.
  TITLE     Crystal structure and mutational analysis of the human TRIM7 B30.2
            domain provide insights into the molecular basis of its binding to
            glycogenin-1
  JOURNAL   J Biol Chem 296, 100772 (2021)
   PUBMED   33989636
  REMARK    GeneRIF: Crystal structure and mutational analysis of the human
            TRIM7 B30.2 domain provide insights into the molecular basis of its
            binding to glycogenin-1.
REFERENCE   4  (bases 1 to 5996)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 5996)
  AUTHORS   Curtino,J.A. and Aon,M.A.
  TITLE     From the seminal discovery of proteoglycogen and glycogenin to
            emerging knowledge and research on glycogen biology
  JOURNAL   Biochem J 476 (21), 3109-3124 (2019)
   PUBMED   31689353
  REMARK    GeneRIF: Glycogenin is at the core of glycogen's structure and
            initiates its glucopolymerization.[review]
            Review article
REFERENCE   6  (bases 1 to 5996)
  AUTHORS   Lomako,J., Mazuruk,K., Lomako,W.M., Alonso,M.D., Whelan,W.J. and
            Rodriguez,I.R.
  TITLE     The human intron-containing gene for glycogenin maps to chromosome
            3, band q24
  JOURNAL   Genomics 33 (3), 519-522 (1996)
   PUBMED   8661012
REFERENCE   7  (bases 1 to 5996)
  AUTHORS   Barbetti,F., Rocchi,M., Bossolasco,M., Cordera,R., Sbraccia,P.,
            Finelli,P. and Consalez,G.G.
  TITLE     The human skeletal muscle glycogenin gene: cDNA, tissue expression
            and chromosomal localization
  JOURNAL   Biochem Biophys Res Commun 220 (1), 72-77 (1996)
   PUBMED   8602861
REFERENCE   8  (bases 1 to 5996)
  AUTHORS   Cao,Y., Mahrenholz,A.M., DePaoli-Roach,A.A. and Roach,P.J.
  TITLE     Characterization of rabbit skeletal muscle glycogenin. Tyrosine 194
            is essential for function
  JOURNAL   J Biol Chem 268 (20), 14687-14693 (1993)
   PUBMED   8325847
REFERENCE   9  (bases 1 to 5996)
  AUTHORS   Viskupic,E., Cao,Y., Zhang,W., Cheng,C., DePaoli-Roach,A.A. and
            Roach,P.J.
  TITLE     Rabbit skeletal muscle glycogenin. Molecular cloning and production
            of fully functional protein in Escherichia coli
  JOURNAL   J Biol Chem 267 (36), 25759-25763 (1992)
   PUBMED   1281472
REFERENCE   10 (bases 1 to 5996)
  AUTHORS   Browner,M.F., Nakano,K., Bang,A.G. and Fletterick,R.J.
  TITLE     Human muscle glycogen synthase cDNA sequence: a negatively charged
            protein with an asymmetric charge distribution
  JOURNAL   Proc Natl Acad Sci U S A 86 (5), 1443-1447 (1989)
   PUBMED   2493642
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BG702275.1, AF087942.1,
            AA191440.1 and AC021059.25.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Oct 16, 2019 this sequence version replaced NM_004130.3.
            
            Summary: This gene encodes a member of the glycogenin family.
            Glycogenin is a glycosyltransferase that catalyzes the formation of
            a short glucose polymer from uridine diphosphate glucose in an
            autoglucosylation reaction. This reaction is followed by elongation
            and branching of the polymer, catalyzed by glycogen synthase and
            branching enzyme, to form glycogen. This gene is expressed in
            muscle and other tissues. Mutations in this gene result in glycogen
            storage disease XV. This gene has pseudogenes on chromosomes 1, 8
            and 13 respectively. Alternatively spliced transcript variants
            encoding different isoforms have been identified.[provided by
            RefSeq, Sep 2010].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF087942.1, AK312283.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000345003.9/ ENSP00000340736.4
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                BG702275.1         136-183
            49-1772             AF087942.1         1-1724
            1773-1890           AA191440.1         30-147              c
            1891-5996           AC021059.25        58972-63077
FEATURES             Location/Qualifiers
     source          1..5996
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q24"
     gene            1..5996
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="glycogenin 1"
                     /db_xref="GeneID:2992"
                     /db_xref="HGNC:HGNC:4699"
                     /db_xref="MIM:603942"
     exon            1..108
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..1154
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /EC_number="2.4.1.186"
                     /note="isoform 1 is encoded by transcript variant 1; GN-1;
                     glycogenin glucosyltransferase"
                     /codon_start=1
                     /product="glycogenin-1 isoform 1"
                     /protein_id="NP_004121.2"
                     /db_xref="CCDS:CCDS3139.1"
                     /db_xref="GeneID:2992"
                     /db_xref="HGNC:HGNC:4699"
                     /db_xref="MIM:603942"
                     /translation="MTDQAFVTLTTNDAYAKGALVLGSSLKQHRTTRRLVVLATPQVS
                     DSMRKVLETVFDEVIMVDVLDSGDSAHLTLMKRPELGVTLTKLHCWSLTQYSKCVFMD
                     ADTLVLANIDDLFDREELSAAPDPGWPDCFNSGVFVYQPSVETYNQLLHLASEQGSFD
                     GGDQGILNTFFSSWATTDIRKHLPFIYNLSSISIYSYLPAFKVFGASAKVVHFLGRVK
                     PWNYTYDPKTKSVKSEAHDPNMTHPEFLILWWNIFTTNVLPLLQQFGLVKDTCSYVNV
                     LSDLVYTLAFSCGFCRKEDVSGAISHLSLGEIPAMAQPFVSSEERKERWEQGQADYMG
                     ADSFDNIKRKLDTYLQ"
     exon            109..244
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            245..419
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            420..582
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            583..709
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            710..929
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            930..980
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     exon            981..5996
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1833..1838
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: AATAAA"
     polyA_site      1853
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="major polyA site"
     regulatory      1867..1872
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: ATTAAA"
     polyA_site      1890
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
     regulatory      4344..4349
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: AATAAA"
     polyA_site      4383
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
     regulatory      5249..5254
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: ATTAAA"
     regulatory      5267..5272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: AATAAA"
     polyA_site      5273
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
     polyA_site      5298
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
     regulatory      5897..5902
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: AATAAA"
     polyA_site      5920
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
     regulatory      5976..5981
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
                     /note="hexamer: AATAAA"
     polyA_site      5996
                     /gene="GYG1"
                     /gene_synonym="GSD15; GYG"
ORIGIN      
        1 tccccgccgt gcctcctcgc tggccgcgct ccctcccggt gccggcttct ctgagtcacc
       61 aacctgaggc tgccccggcc gcctgcgcac ccggcagcac catgacagat caggcctttg
      121 tgacactaac cacaaacgat gcctacgcca aaggtgccct ggtcctggga tcatctctga
      181 aacagcacag gaccaccagg aggctggtcg tgctcgccac ccctcaggtc tcagactcca
      241 tgagaaaagt tttagagaca gtctttgatg aagtcatcat ggtagatgtc ttggacagtg
      301 gcgattctgc tcatctaacc ttaatgaaga ggccagagtt gggtgtcacg ctgacaaagc
      361 tccactgctg gtcgcttaca cagtattcaa aatgtgtatt catggatgca gatactctgg
      421 tcctagcaaa tattgatgat ctttttgaca gagaagaatt gtcagcagca ccagacccag
      481 ggtggcctga ctgcttcaat tccggagtct tcgtttatca gccttcagtt gaaacataca
      541 atcagctgtt gcatcttgct tctgagcaag gtagttttga tggtggggac caaggcatac
      601 tgaacacatt ttttagcagc tgggcaacaa cagatatcag aaaacacctg ccgtttattt
      661 ataacctaag cagcatctct atatactcct acctcccggc atttaaagtg tttggtgcaa
      721 gtgccaaagt tgtgcatttc ctgggacgag tcaaaccatg gaattatact tatgatccca
      781 aaacaaaaag tgtcaaaagt gaggcccatg atcccaacat gactcatcca gagtttctca
      841 tcctgtggtg gaacatcttt accaccaacg ttttacctct gcttcaacaa tttggccttg
      901 tcaaagacac ctgctcatat gtaaatgtgc tttcagactt ggtctataca ctggctttct
      961 cttgtggctt ctgtagaaag gaagatgtct caggagccat atcacatctg tcccttgggg
     1021 agatcccagc tatggcacag ccgtttgtat cctcggaaga acggaaggaa cgatgggaac
     1081 agggccaggc tgattatatg ggagcagatt cctttgacaa catcaagagg aaacttgaca
     1141 cttacctcca gtagaaacac tgcatttttc tgtgaacaca tccacttcac aagccttgtt
     1201 tctgatactt agtatctaga gctgggttga gaaaagtctg ttacagttgc tagaggtttt
     1261 cattaaaact tatcagatga gaggcttttt taggataaga ggtgagaact gggcaaaagt
     1321 tgtgaagcag caattctgtt atatggacag tgttctgctt tttaatccta tttagcttgt
     1381 ttcagaaatt ctcacttttg ttgactgcca acatacaaag taagggaaac tcaagatatt
     1441 aagatggctg tatcagttct taaaatctgc agagcctggt tcaaaatcag tcactccctt
     1501 cagaagcaga catggcatct gttccttgct tgcttgttgg ttgtgtacct ttcacgagac
     1561 ctgaatttta gaattgccca gtgctgccag agtgagtgag tgtaattctc ctttcaggta
     1621 aagataggct atctcaacac tgctgagtga ttcataaaca tatcaaccaa tagcattaac
     1681 ccattttatt tcctgtcctt agtgtctgaa gatgctcacc agttttctgt gtacagtaag
     1741 gcagcatgct aaaatgcttt tgttcagttc tgtatatttg aaaatagcag tgtgttctct
     1801 gatggttacc tgcagtggca ccctgtacaa aaaataaaag acttattgct gtatcttggt
     1861 tgtttaatta aattaaggaa tttcaccata cacccttgaa caaatctatt agggaatttt
     1921 tcacaatttt tggaatttgt catagtttta aaaaagtgta aagcttgaca ttgggatata
     1981 tgctttaaaa actggtatct atgatttcaa tctaattgtt tttctgtgat ggtgatggat
     2041 ctgacagatc agaacaaacc gagatcaaac ttacatagtg tcatccacac tgcacctctc
     2101 tattaagtgg gtatttagct atttagaata ttttaacctt aaagtcattc ctaactgtca
     2161 gaatcaatac tgggtccagt ccctactagt attttatcta tgatttaaaa tgatagaatg
     2221 gaaaagcgta tttattaaat ttatagatca ttctaggttg taagagatgg caagctaaag
     2281 aagggtagga tccaagatga ccttttaaaa ctaaaatgag tggtcagaaa tgattctatg
     2341 gaagaaaaca ggacagttaa ccatgacagg aagaaacttt agaggtttga ttgggcaaaa
     2401 gctgcaaagc ttttgtgact tagccttcaa agtcaccctc cttattcata ttgatgtgaa
     2461 ttaatataca agcatataga cagcttaagt caagaatggt tggggccacc ttgaaggctg
     2521 ttaccatagg agctcaataa gaacctgagg atttacctag aattataaaa tattaaatga
     2581 taaatgactt ctgaaactag ctatttggac tggtgaagaa tgagtcgcta ttgatcttca
     2641 agtacaatga agcatttacc aaagatttat ttaagtgcct ccatgtgtca gatgctgtgg
     2701 tacaaagaag gacttctcaa aattttagct agtcagaggt ctttctggct tccgagtccc
     2761 tggttaagat gaacagaaac acagtcttca gatataaaat gtcttatttt tgtggccatt
     2821 cagttgcatt caacgttaat tttttctatt tactaccgtt cattctctat tttttacaca
     2881 gtagcataac aaagctctaa ggtggaaaag ctgacatagt tttaaatttt tttttttttt
     2941 tttttttttc ttgaggcaga gtcttgctct gtcagtcagt caccaggctg gagtgcagtg
     3001 gtgcagtctc ggctcactgc aacctctgcc tcctggattc aagagattct cctacctcag
     3061 cctcctgagt agctgggact acaggcacgc accaccacgc ccagctaaat tttgtatttt
     3121 tagtagagac aggtttcacc atgttgccag gatggtctca atctcttgac ctcgtgatcc
     3181 accggccttg gcctcccaaa gtgctgggat tacaggcgtg agccactgca cccagcaaat
     3241 ttttaaattt caaataagta gtgaaggcta ttattaactt ttggaatcag aaagaatgac
     3301 aagcttacca taagacatag catataatgc tgtcaagtta tttggctaga aaatcactga
     3361 actaaacatt cttttccttc tatgatctat gtcttaaggt gaagtattaa ctaacttttc
     3421 catgtaaagc tatacaaata ttggaaaatc ttttctaggg agtccagaat actaagggtt
     3481 acttagtaaa atgtataaaa aggcaacagt aattcaaatt acaagattta tatttgcaga
     3541 ggtgatccat atatacttat ccccttgcag tggctggtat gacctttggt tgtaagacaa
     3601 acttgcccac aacagaggtc aaatccatgc ctttggagat tagctccatg gtggatggag
     3661 ctatggttta tgcataaagt aaatgtttgt ttaccttaat tctccttata cccatattgt
     3721 cctgctgtat aacacatttt gcagatattt tgaagttaat gtgttaaaaa cttgaggtta
     3781 aacatttgag tttttgttaa gagccaaaca tcaaatgtgc ccttatattt ttaatgaatc
     3841 tcatccaaat gctaatgcat aaaccttgac aagtagtata aataaaacaa gaaaaaaata
     3901 cagcaatgtc tttgccattc cccaaaacaa agcacacact gccgaagatc attagtactc
     3961 actggtaaca aactacatag ggttagtttg tatttccaat tctagagctg taattttaag
     4021 gacaaaatgt acaatgattg attaagagtg ctatctgtgt atatataggt attatcacaa
     4081 ctcctttttt tcttccagat gaagaaatta attgggacca atgtttttag atcaaggcat
     4141 tttaaataag cactcttgat ttctgaacaa gaatttcaac cagctaaatt gagcaaaata
     4201 aagttagtta ggatatgagg acattattct gttacagtaa tcttcatgta ctctcaaaaa
     4261 aatgtaacac ttgcatagaa atgtcacaat taatgaagga ttttatttga agataaagtc
     4321 aaaattatgg caccgaggaa ggtaataaac atttgaaatt tttattgatt tttaaattta
     4381 aaatccagtt ttaaccacaa aattgtttga atcacaagtg gtaatacaat gtcttcaata
     4441 tttttctaaa gttatttttc tatataataa taagacaaca gcatagcata taggaagttt
     4501 tcattccagt ggctttttta tatatttatc cttcttagga aggacaaatt aaatttttta
     4561 aattaaactt ttaaaatata acaacatcta acagaactgt acaaaacaaa gagacatttt
     4621 ttaaacaact tgccaaactt acttatgagt gtgttttaaa aacaactttg taaatgtctg
     4681 ggcaaagaag caagctgtcc tccctttacc ttcatagtga gtttgtaagg ctttgtcttt
     4741 gtaagcagaa agagtagact gtgttgtttt ttgccaaaaa ctgtttatac ttaatctcac
     4801 tgaagtattg ctatatggag aacccatact ctgatcaact tgattttttg tgtgtaatgc
     4861 ttgatctacc aggtaacttc ccaactgctc ctaatgctag cgggctaatc ccacattatt
     4921 attccactat catccctgca gaaaggtctt ggttttgatg aaaatcagcc ctttccttac
     4981 ctgctactgc ctcaaaaagg gaccaggaag attctagctg gctaattcac tgttcccttt
     5041 gagcaagaaa acggcacagg gagaaaagga cttatctggt gagagatttg gcatatacct
     5101 tcaatgtgtg ccctataaca caacattgtc tccgatctca tctttctatc aaatgacttc
     5161 caacactctt aagtctcagg tattcttaaa tctgtatcat caaacatgaa gcttctcttg
     5221 tttgttagag taattaatct ttctttggat taaagtttcc ctttgaaata aaaccaccta
     5281 cctaatctga ctgctaaatt tctagcttct ttgttttaaa tatgctcagg agtcaaccca
     5341 aattctgcag caaataagtt tgcttattaa caaaaaagta aaaaaaaaag aaaagaaaaa
     5401 agatgactaa ttctacagat agctgtaagg atgaattact caagttcaaa atcaaattct
     5461 gattctaaac acataacaat tgtttacatt caggattaag atgtctttaa gagttgaaac
     5521 gactttggag atcatccagc ccaacttcca tccagatatc acgcctctca catatagtag
     5581 tcttctgaat tataaaaatt tataaagtta cttccaaaaa aagctacata aataaaaatt
     5641 atctatttat agaaatatct atttagcagt tccataattt aaaatattca aatcaaattg
     5701 ggtaggactg gtttgcctct cactcccaca gactatattt atacctcaga cacagcaagt
     5761 tacatttaaa caatgagtgt agtactactt aactaaaatg gaaaaaatag tactcttaac
     5821 ataatcccta attttttcat gaacataaaa ctccaagtca tttatgtgaa ctatatctca
     5881 atgtagctgt aggaaaaata aaaacctgtg ctaacctgga ctttggtctc atttaagatt
     5941 tggttctgga atgcaaatat ggtttttgaa agcccaataa aattaattct tgtata
//
