LOCUS       XM_047418690            1540 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens guanylate kinase 1 (GUK1), transcript
            variant X5, mRNA.
ACCESSION   XM_047418690
VERSION     XM_047418690.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000001.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1540
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
     gene            1..1540
                     /gene="GUK1"
                     /gene_synonym="GMK"
                     /note="guanylate kinase 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 17
                     ESTs, 103 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     120 samples with support for all annotated introns"
                     /db_xref="GeneID:2987"
                     /db_xref="HGNC:HGNC:4693"
                     /db_xref="MIM:139270"
     CDS             721..1437
                     /gene="GUK1"
                     /gene_synonym="GMK"
                     /codon_start=1
                     /product="guanylate kinase isoform X3"
                     /protein_id="XP_047274646.1"
                     /db_xref="GeneID:2987"
                     /db_xref="HGNC:HGNC:4693"
                     /db_xref="MIM:139270"
                     /translation="MDLRRRLPGDLPSRSSCGDHVPGRHVGPQACGAERAFGSWEEHP
                     AEEAAPGAQRHLWLQRVPYHEEPEARRGERQREVMQRDIAAGDFIEHAEFSGNLYGTS
                     KVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPIYISVQPPSLHVLEQRLRQRNTETE
                     ESLVKRLAAAQADMESRNQESSKDRRLRLAVCSRHPGPIQDQGSSIEPPPWQAIRQLC
                     ALGQHVEWRRCCPCGWNILG"
ORIGIN      
        1 agtgggcgga agaggtggcc ccggatgctg cggcgcccgc tggccgggct ggctgcggcc
       61 gccctgggcc gggccccacc ggacggcttg ctctgctctt tacctggggt tgctgtcgag
      121 gaccctgtgc aagactcggc cggtttttct ttctccctga tggacagacc caaacatagc
      181 cgcgcagcat cgtgaagggc tggggccttc actcctctgt ggctctggaa gagcccgatt
      241 tcctcaggag gtaaaggaat gttcctgtcc cccccgggga aagaaagtga aaatgaaagc
      301 gccctggctg ctcctggtgt ggtcccattt aaaacgaggt tgctgaaggc caggatgcgt
      361 gctacccgga tgtgtgccca gaaaccctgc agccaagagc agccgcctgg accaccagcc
      421 tccccttcat ccacctggcc cagcccagag cccaggccca cgtctggtgg tttgtgtctt
      481 acgagaggcc aggcgggggc tgaattctct cggttctcag aaggtcaagc cctctgttag
      541 catctcctcg aacagtgggc cgggggcaag gtggtgactc tgttcagtcc ttaggatggc
      601 tggaagccag aaggaggaga ttatgccgcc acagcaggga gtgcctttcc aggaaagcgg
      661 ctgctggggc agcatgggag cccagtccag ggagcgttct ggcagagacc attccggaac
      721 atggatctgc gccggcggct cccaggagac cttccatctc ggagctcctg tggagaccac
      781 gtgcctggca ggcatgtcgg gccccaggcc tgtggtgctg agcgggcctt cgggagctgg
      841 gaagagcacc ctgctgaaga ggctgctcca ggagcacagc ggcatctttg gcttcagcgt
      901 gtcccatacc acgaggaacc cgaggcccgg cgaggagaac ggcaaaggga ggtgatgcag
      961 cgtgacatag cagccggcga cttcatcgag catgccgagt tctcggggaa cctgtatggc
     1021 acgagcaagg tggcggtgca ggccgtgcag gccatgaacc gcatctgtgt gctggacgtg
     1081 gacctgcagg gtgtgcggaa catcaaggcc accgatctgc ggcccatcta catctctgtg
     1141 cagccgcctt cactgcacgt gctggagcag cggctgcggc agcgcaacac tgaaaccgag
     1201 gagagcctgg tgaagcggct ggctgctgcc caggccgaca tggagagcag aaatcaagaa
     1261 agctcaaagg accggcgcct gaggcttgct gtctgttctc ggcaccccgg gcccatacag
     1321 gaccagggca gcagcattga gccaccccct tggcaggcga tacggcagct ctgtgccctt
     1381 ggccagcatg tggagtggag gagatgctgc ccctgtggtt ggaacatcct ggggtgaccc
     1441 ccgacccagc ctcgctgggc tgtcccctgt ccctatctct cactctggac ccagggctga
     1501 catcctaata aaataactgt tggattagaa actccataaa
//
