LOCUS       NM_004286               4905 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  Homo sapiens GTP binding protein 1 (GTPBP1), mRNA.
ACCESSION   NM_004286 NM_014027
VERSION     NM_004286.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4905)
  AUTHORS   Salpietro,V., Maroofian,R., Zaki,M.S., Wangen,J., Ciolfi,A.,
            Barresi,S., Efthymiou,S., Lamaze,A., Aughey,G.N., Al Mutairi,F.,
            Rad,A., Rocca,C., Cali,E., Accogli,A., Zara,F., Striano,P.,
            Mojarrad,M., Tariq,H., Giacopuzzi,E., Taylor,J.C., Oprea,G.,
            Skrahina,V., Rehman,K.U., Abd Elmaksoud,M., Bassiony,M., El
            Said,H.G., Abdel-Hamid,M.S., Al Shalan,M., Seo,G., Kim,S., Lee,H.,
            Khang,R., Issa,M.Y., Elbendary,H.M., Rafat,K., Marinakis,N.M.,
            Traeger-Synodinos,J., Ververi,A., Sourmpi,M., Eslahi,A., Khadivi
            Zand,F., Beiraghi Toosi,M., Babaei,M., Jackson,A.,
            Bertoli-Avella,A., Pagnamenta,A.T., Niceta,M., Battini,R.,
            Corsello,A., Leoni,C., Chiarelli,F., Dallapiccola,B., Faqeih,E.A.,
            Tallur,K.K., Alfadhel,M., Alobeid,E., Maddirevula,S., Mankad,K.,
            Banka,S., Ghayoor-Karimiani,E., Tartaglia,M., Chung,W.K., Green,R.,
            Alkuraya,F.S., Jepson,J.E.C. and Houlden,H.
  CONSRTM   SYNAPS Study Group
  TITLE     Bi-allelic genetic variants in the translational GTPases GTPBP1 and
            GTPBP2 cause a distinct identical neurodevelopmental syndrome
  JOURNAL   Am J Hum Genet 111 (1), 200-210 (2024)
   PUBMED   38118446
  REMARK    GeneRIF: Bi-allelic genetic variants in the translational GTPases
            GTPBP1 and GTPBP2 cause a distinct identical neurodevelopmental
            syndrome.
REFERENCE   2  (bases 1 to 4905)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 4905)
  AUTHORS   Zinoviev,A., Goyal,A., Jindal,S., LaCava,J., Komar,A.A.,
            Rodnina,M.V., Hellen,C.U.T. and Pestova,T.V.
  TITLE     Functions of unconventional mammalian translational GTPases GTPBP1
            and GTPBP2
  JOURNAL   Genes Dev 32 (17-18), 1226-1241 (2018)
   PUBMED   30108131
  REMARK    GeneRIF: GTPBP1 possesses eEF1A-like elongation activity,
            delivering cognate aminoacyl-transfer RNA to the ribosomal A site
            in a GTP-dependent manner. It also stimulates exosomal degradation
            of mRNAs in elongation complexes.
REFERENCE   4  (bases 1 to 4905)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 4905)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 4905)
  AUTHORS   Senju,S., Iyama,K., Kudo,H., Aizawa,S. and Nishimura,Y.
  TITLE     Immunocytochemical analyses and targeted gene disruption of GTPBP1
  JOURNAL   Mol Cell Biol 20 (17), 6195-6200 (2000)
   PUBMED   10938096
REFERENCE   7  (bases 1 to 4905)
  AUTHORS   Kudo,H., Senju,S., Mitsuya,H. and Nishimura,Y.
  TITLE     Mouse and human GTPBP2, newly identified members of the GP-1 family
            of GTPase
  JOURNAL   Biochem Biophys Res Commun 272 (2), 456-465 (2000)
   PUBMED   10833435
REFERENCE   8  (bases 1 to 4905)
  AUTHORS   Dunham,I., Shimizu,N., Roe,B.A., Chissoe,S., Hunt,A.R.,
            Collins,J.E., Bruskiewich,R., Beare,D.M., Clamp,M., Smink,L.J.,
            Ainscough,R., Almeida,J.P., Babbage,A., Bagguley,C., Bailey,J.,
            Barlow,K., Bates,K.N., Beasley,O., Bird,C.P., Blakey,S.,
            Bridgeman,A.M., Buck,D., Burgess,J., Burrill,W.D., O'Brien,K.P. et
            al.
  TITLE     The DNA sequence of human chromosome 22
  JOURNAL   Nature 402 (6761), 489-495 (1999)
   PUBMED   10591208
  REMARK    Erratum:[Nature 2000 Apr 20;404(6780):904]
REFERENCE   9  (bases 1 to 4905)
  AUTHORS   Goretzki,L. and Mueller,B.M.
  TITLE     Low-density-lipoprotein-receptor-related protein (LRP) interacts
            with a GTP-binding protein
  JOURNAL   Biochem J 336 (Pt 2) (Pt 2), 381-386 (1998)
   PUBMED   9820815
REFERENCE   10 (bases 1 to 4905)
  AUTHORS   Senju,S. and Nishimura,Y.
  TITLE     Identification of human and mouse GP-1, a putative member of a
            novel G-protein family
  JOURNAL   Biochem Biophys Res Commun 231 (2), 360-364 (1997)
   PUBMED   9070279
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BF001482.1, BC014075.1,
            AK095950.1, BC016030.1 and BC001701.2.
            
            On Nov 22, 2018 this sequence version replaced NM_004286.4.
            
            Summary: This gene is upregulated by interferon-gamma and encodes a
            protein that is a member of the AGP11/GTPBP1 family of GTP-binding
            proteins. A structurally similar protein has been found in mouse,
            where disruption of the gene for that protein had no observable
            phenotype. [provided by RefSeq, Jul 2008].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803611.199191.1,
                                           SRR1660807.264517.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000216044.10/ ENSP00000216044.5
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-20                BF001482.1         97-116              c
            21-2368             BC014075.1         1-2348
            2369-3462           AK095950.1         72-1165
            3463-4895           BC016030.1         1777-3209
            4896-4905           BC001701.2         555-564
FEATURES             Location/Qualifiers
     source          1..4905
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="22q13.1"
     gene            1..4905
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="GTP binding protein 1"
                     /db_xref="GeneID:9567"
                     /db_xref="HGNC:HGNC:4669"
                     /db_xref="MIM:602245"
     exon            1..204
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..2022
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="G-protein 1"
                     /codon_start=1
                     /product="GTP-binding protein 1"
                     /protein_id="NP_004277.2"
                     /db_xref="CCDS:CCDS13977.2"
                     /db_xref="GeneID:9567"
                     /db_xref="HGNC:HGNC:4669"
                     /db_xref="MIM:602245"
                     /translation="MATERSRSAMDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDS
                     DCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSD
                     GTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLE
                     VRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGF
                     DSEGNVVNKPDSHGGSLEWTKICEKSTKVITFIDLAGHEKYLKTTVFGMTGHLPDFCM
                     LMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGC
                     RKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREE
                     EPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRM
                     PVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPR
                     YQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKA
                     VGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLTKRDEGGPSGGPAVGAPPPGDEASS
                     VGAGQPAASSNLQPQPKPSSGGRRRGGQRHKVKSQGACVTPASGC"
     exon            205..316
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            317..497
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            498..846
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            847..970
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1085
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1230
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1413
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1549
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1728
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1729..1929
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     exon            1930..4905
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3536..3541
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="hexamer: AATAAA"
     polyA_site      3553
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="major polyA site"
     regulatory      4877..4882
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="hexamer: AATAAA"
     polyA_site      4905
                     /gene="GTPBP1"
                     /gene_synonym="GP-1; GP1; HSPC018; NEDFET1"
                     /note="major polyA site"
ORIGIN      
        1 aagttattaa agatggcgac ggagcgcagt cgctccgcga tggactcgcc ggtcccggcc
       61 tctatgttcg cccccgagcc cagctccccg ggggcggcca gggccgcggc ggccgccgcc
      121 cgactccacg gcggctttga ctcggactgc agcgaggacg gcgaggcgct caacggcgag
      181 ccagagctgg acctcaccag caagctggtt ctagtgagcc ctacatcaga gcagtatgac
      241 agcctacttc ggcagatgtg ggagaggatg gacgagggat gcggagagac catatatgtc
      301 attgggcagg gatcagatgg gactgagtat gggctgagtg aagctgacat ggaggcctcc
      361 tacgccacag tgaagagcat ggcggaacag atagaggccg atgtcatcct tctgcgggaa
      421 cggcaagaag ctgggggccg cgtgcgtgat tacctggtcc ggaaacgagt aggagacaat
      481 gacttcctgg aggtcagggt agcagtggtg ggcaacgtgg atgctggcaa aagcacgctt
      541 ctgggggtcc tgacacatgg ggagctggac aatggccgag gctttgcccg ccagaaactc
      601 ttccgccaca aacatgaaat tgaatctggt cgcaccagca gtgtgggcaa cgacattctg
      661 ggctttgaca gtgaaggcaa tgtagtgaac aagcctgaca gccacggcgg cagcctggag
      721 tggaccaaga tctgtgagaa gtccacgaaa gtcattacct tcatcgactt ggctggtcat
      781 gagaagtacc tgaaaaccac tgtcttcggc atgacaggcc atctgcctga cttctgcatg
      841 ctcatggtgg gcagcaatgc tggcatcgtg gggatgacca aagaacacct gggcttggca
      901 ctggcactca atgtacctgt ctttgtggta gtcaccaaga ttgacatgtg tcctgccaac
      961 atcctgcaag aaaccctgaa gctgttacag cgcctgctga agtcaccagg ctgccggaag
     1021 atccccgtgc tggtgcagag caaagatgat gtgattgtca cagcctccaa cttcagctct
     1081 gaaaggatgt gcccgatatt ccagatctcc aacgttacag gcgagaacct agatctgctg
     1141 aagatgttcc tcaacctcct ctccccccgc accagctaca gggaggagga gcctgctgag
     1201 tttcagattg atgacaccta ctccgtcccg ggtgtgggga cagtggtttc ggggacaaca
     1261 ctgagaggcc tgatcaagct gaatgacacg ctgctgctgg gcccagaccc cttgggtaac
     1321 ttcctgtcca ttgctgtcaa atccatccat cgcaagcgca tgcctgtcaa ggaggtgcgg
     1381 ggtggccaga cagcatcctt tgcgctgaag aagatcaagc gctcgtccat ccggaagggc
     1441 atggtgatgg tttccccacg tttgaatccc caagcctcct gggagtttga ggccgagatt
     1501 ctcgtcctcc accaccccac cacaattagc ccgcgctacc aggccatggt gcactgtggg
     1561 agcatcaggc agacagccac cattctgagc atggacaagg actgtctgcg cactggggac
     1621 aaggccactg tacacttccg cttcatcaag acccctgagt acctgcacat agaccagcgg
     1681 ctggtgttcc gggaaggccg caccaaggct gtcggcacca tcaccaagct cctccagacc
     1741 accaacaact ccccaatgaa ctccaagccg cagcagatta aaatgcagtc gacgaaaaag
     1801 ggccccctga cgaaacgaga cgaggggggc ccgtctggtg ggccagcagt aggagcaccc
     1861 ccacctggag atgaagcctc ctctgtaggg gcagggcaac cagctgcgtc cagcaatctc
     1921 cagcctcagc ctaagcccag cagtggaggc cggcgacgag ggggccagcg ccacaaggtg
     1981 aagtcccagg gggcctgtgt gactcctgcc agcggctgct gaaccttccc ctggcccacc
     2041 ctcaccaccc aaggggtcat catctctggc caccactcca ccagatgggc agagcagcta
     2101 tgaccgccac ccagccctcc cgctcaggcc acagccggag cctccgcatt gcccccaccc
     2161 ccattttcca ggggggttgt aatttataag ctgacgaagg tagccagact tccggaggac
     2221 tgaccatctc tcactgtcct ccccaccttc ttcctcactc acacattttt tgtacatctg
     2281 ggcccttagt ttttattctg tttattatat gtctctgtct ctctctattg tgtgtgtgtg
     2341 tgtgtgtgtg tgtgtgtgtg tgtgtgtggt gcaggagtgc cacccccagg gccctgtcaa
     2401 cctctctttt ctcctccatg gctgtctgcc tgcgtatctg tctctgagaa tcctcggggc
     2461 ggtcagggga tgtcaggagg ggaaggagcc gccctcccta tcttgctgct cctcttggca
     2521 ctcaggggca ccttccatgg agccagaccg ggtggagggg cttctgggat ttggtgtctg
     2581 ctgctgccag agcaggaacc cccagtctag gacttgggca ttttaacagg gagaaagtag
     2641 tggcttccct tttctctctc tcctcctttt tccctttaag cccacagatt caggtcatgc
     2701 caaaagctct ctggttgtaa cctggagaca tgtggagggg aatggcgatg ggattatagg
     2761 actctcccca tctcgggccc tgaccctgac ccttgccacc aacccaaaga cagctggtgg
     2821 gtttcccctt ggagacaatc ctgcgtttgc ctgggccggc cctggctgcc ctcagctttc
     2881 gctgatctgc ccggcctgga gcctcccatc accccgcttc ttgttgggcc tcaggcactg
     2941 gttaccagaa gggggtctgg gtctgctcag gatcatgttt tgtagcacct cctgttggag
     3001 gggtggaggg atgttcccct gagccaggct gagactagaa ccccatcttc cctgagccag
     3061 gctgagacta gaaccccatc ttccccacca cgccacccct gtggctgcta caggagcaca
     3121 gtagtgaagg cctgagctcc aggtttgaaa gacccaactg gagcgtgggg cgggcaggca
     3181 ggggttagtg aaaggacact tccagggtta ggacagagca tttagccttc tggaagaacc
     3241 cctgcctggg gtgggactgt gcaggccaga gaaggtggca tgggcctgaa cccacctgga
     3301 ctgacttctg cactgaagcc acagatggag ggtaggctgg tgggtggggg tggttcgttc
     3361 tctagccggg gcagacaccc agctggctgg gtccttcctc agccttgcct cctcctgtcc
     3421 ccaacccttt cctttcctcc tgcttgcgga ctgctggtcc cctctccttc cctccttcca
     3481 gctgtttcta gttaccacct acccctggcc gtggactgat cagaccagca ttcaaaataa
     3541 aagtttgttc caagttgaca gtgtggtgct ccctgcccag cccctccagg tggaggtgct
     3601 gccacgggaa cgcagttgct ctgcctgccc tggggcccct ggcgacagct gggagcaggg
     3661 cagtgctgtg aggagcccag ctttcccagt caggcaggca tggcttccgt gttcaggctc
     3721 cctcaccagc tggtgacacg ggacaagctt acaaaccttc tctgaacctc agttttctca
     3781 tttacaagag gcaaagccat ccatcacctt gtgtggattc agagaatgtg aggccctggg
     3841 gtgtcctaca caagggaaag gcttgctcag tgagcggtct gcacaccgtt agccaccctg
     3901 ccacctctgt gccctgggca ggctccaaag gaaagctctg gctgggactg ccaggagtct
     3961 cacacgctcc tgttgacatt cccagcagcc gcccctgagg tcgatgtttg ttctgttttt
     4021 ctttttcttt tttgagacgg agtctcgctg tgttgccagg ctggagtgca gtggtgtgat
     4081 ctctgctcac tgcaacctcc gcctgccagt ttcaagtgat tctctgcctc agccttctga
     4141 gtagctggga ctacaggtgc acgccaccac gcccagctaa ctttttgtat tttagtagag
     4201 acagggtttc gccatgtcgg ccagggtggt cttgatctcc tgacctcatg atccacccgc
     4261 ctcagcctcc caaagtgctg ggattacagg tatgagccac cgcaccgggc ctgttctatt
     4321 tttctagtta agggaactga agctcagaga ggtgtcacca gcaggtgttc attcccatgc
     4381 cagccttgcc ccccggcttt tcccaggcag gctcctgcgt gcccactggc tccagcctgg
     4441 tcctctgtct cttggctgct tcactcctgc tctttgtccc gactctggcc ctgcttacag
     4501 gggccactac ctgctggtgc ctccataaca agcgtctggc gttgagaccc ctggcatggc
     4561 aggggctttg gggtctggtt tccacaaggc ttagccatgg cagaacctcg ttttatttta
     4621 actctttgcc cctacaaaca aacagcagta cttgccagaa ccattcttgg gattcaggag
     4681 ctcgggcgac tgccttggcc tctggccgca cccaggaggg tggggttgga tctgtgtagt
     4741 tgccaggccc acacctgcca gcagggggct gactggatcc atgctttact gtgtttaatg
     4801 ggggtaacag gggtccctac agccctccca gctaaacatt tggaacaaaa caccagccct
     4861 tttgtagtgg atgcagaata aaattgttaa tccaatcacc tccaa
//
