LOCUS       NM_012086               4261 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens general transcription factor IIIC subunit 3 (GTF3C3),
            transcript variant 1, mRNA.
ACCESSION   NM_012086
VERSION     NM_012086.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4261)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 4261)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 4261)
  AUTHORS   Huang,S., Chen,J., Wang,H., Sun,B., Wang,H., Zhang,Z., Zhang,X. and
            Chen,Z.
  TITLE     Influenza A virus matrix protein 1 interacts with hTFIIIC102-s, a
            short isoform of the polypeptide 3 subunit of human general
            transcription factor IIIC
  JOURNAL   Arch Virol 154 (7), 1101-1110 (2009)
   PUBMED   19521658
REFERENCE   4  (bases 1 to 4261)
  AUTHORS   Dumay-Odelot,H., Marck,C., Durrieu-Gaillard,S., Lefebvre,O.,
            Jourdain,S., Prochazkova,M., Pflieger,A. and Teichmann,M.
  TITLE     Identification, molecular cloning, and characterization of the
            sixth subunit of human transcription factor TFIIIC
  JOURNAL   J Biol Chem 282 (23), 17179-17189 (2007)
   PUBMED   17409385
REFERENCE   5  (bases 1 to 4261)
  AUTHORS   Kaltenbach,L.S., Romero,E., Becklin,R.R., Chettier,R., Bell,R.,
            Phansalkar,A., Strand,A., Torcassi,C., Savage,J., Hurlburt,A.,
            Cha,G.H., Ukani,L., Chepanoske,C.L., Zhen,Y., Sahasrabudhe,S.,
            Olson,J., Kurschner,C., Ellerby,L.M., Peltier,J.M., Botas,J. and
            Hughes,R.E.
  TITLE     Huntingtin interacting proteins are genetic modifiers of
            neurodegeneration
  JOURNAL   PLoS Genet 3 (5), e82 (2007)
   PUBMED   17500595
REFERENCE   6  (bases 1 to 4261)
  AUTHORS   Koch,H.B., Zhang,R., Verdoodt,B., Bailey,A., Zhang,C.D., Yates,J.R.
            3rd, Menssen,A. and Hermeking,H.
  TITLE     Large-scale identification of c-MYC-associated proteins using a
            combined TAP/MudPIT approach
  JOURNAL   Cell Cycle 6 (2), 205-217 (2007)
   PUBMED   17314511
REFERENCE   7  (bases 1 to 4261)
  AUTHORS   Zhan,Y., Hegde,R., Srinivasula,S.M., Fernandes-Alnemri,T. and
            Alnemri,E.S.
  TITLE     Death effector domain-containing proteins DEDD and FLAME-3 form
            nuclear complexes with the TFIIIC102 subunit of human transcription
            factor IIIC
  JOURNAL   Cell Death Differ 9 (4), 439-447 (2002)
   PUBMED   11965497
  REMARK    GeneRIF: DEDD and FLAME-3 form nuclear complexes with TFIIIC102
REFERENCE   8  (bases 1 to 4261)
  AUTHORS   Hsieh,Y.J., Wang,Z., Kovelman,R. and Roeder,R.G.
  TITLE     Cloning and characterization of two evolutionarily conserved
            subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their
            involvement in functional interactions with TFIIIB and RNA
            polymerase III
  JOURNAL   Mol Cell Biol 19 (7), 4944-4952 (1999)
   PUBMED   10373544
REFERENCE   9  (bases 1 to 4261)
  AUTHORS   Behar,G., Coleclough,C., Houlgatte,R., Auffray,C. and Lefkovits,I.
  TITLE     Human lymphocyte cDNA ordered library analyzed by 2D gel
            electrophoresis. 3. Analysis of individual clones
  JOURNAL   Appl Theor Electrophor 5 (2), 99-105 (1995)
   PUBMED   8573604
REFERENCE   10 (bases 1 to 4261)
  AUTHORS   Jang,K.L., Collins,M.K. and Latchman,D.S.
  TITLE     The human immunodeficiency virus tat protein increases the
            transcription of human Alu repeated sequences by increasing the
            activity of the cellular transcription factor TFIIIC
  JOURNAL   J Acquir Immune Defic Syndr (1988) 5 (11), 1142-1147 (1992)
   PUBMED   1403646
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK314718.1 and AC012486.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_012086.4.
            
            Summary: The protein encoded by this gene is part of the TFIIIC2
            complex, which binds to the promoters of small nuclear and
            cytoplasmic RNA genes in order to recruit RNA polymerase III. The
            TFIIIC2 complex is composed of six subunits. Two transcript
            variants encoding different isoforms have been found for this gene.
            [provided by RefSeq, Oct 2011].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803616.87922.1,
                                           SRR1803614.88328.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000263956.8/ ENSP00000263956.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2733              AK314718.1         27-2759
            2734-4261           AC012486.9         21560-23087         c
FEATURES             Location/Qualifiers
     source          1..4261
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q33.1"
     gene            1..4261
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="general transcription factor IIIC subunit 3"
                     /db_xref="GeneID:9330"
                     /db_xref="HGNC:HGNC:4666"
                     /db_xref="MIM:604888"
     exon            1..174
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..2733
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="isoform 1 is encoded by transcript variant 1;
                     general transcription factor 3C polypeptide 3; TF3C-gamma;
                     TFIIIC 102 kDa subunit; transcription factor IIIC subunit
                     gamma; general transcription factor IIIC, polypeptide 3,
                     102kDa"
                     /codon_start=1
                     /product="general transcription factor 3C polypeptide 3
                     isoform 1"
                     /protein_id="NP_036218.1"
                     /db_xref="CCDS:CCDS2316.1"
                     /db_xref="GeneID:9330"
                     /db_xref="HGNC:HGNC:4666"
                     /db_xref="MIM:604888"
                     /translation="MSGFSPELIDYLEGKISFEEFERRREERKTREKKSLQEKGKLSA
                     EENPDDSEVPSSSGINSTKSQDKDVNEGETSDGVRKSVHKVFASMLGENEDDEEEEEE
                     EEEEEEEEETPEQPTAGDVFVLEMVLNRETKKMMKEKRPRSKLPRALRGLMGEANIRF
                     ARGEREEAILMCMEIIRQAPLAYEPFSTLAMIYEDQGDMEKSLQFELIAAHLNPSDTE
                     EWVRLAEMSLEQDNIKQAIFCYTKALKYEPTNVRYLWERSSLYEQMGDHKMAMDGYRR
                     ILNLLSPSDGERFMQLARDMAKSYYEANDVTSAINIIDEAFSKHQGLVSMEDVNIAAE
                     LYISNKQYDKALEIITDFSGIVLEKKTSEEGTSEENKAPENVTCTIPDGVPIDITVKL
                     MVCLVHLNILEPLNPLLTTLVEQNPEDMGDLYLDVAEAFLDVGEYNSALPLLSALVCS
                     ERYNLAVVWLRHAECLKALGYMERAAESYGKVVDLAPLHLDARISLSTLQQQLGQPEK
                     ALEALEPMYDPDTLAQDANAAQQELKLLLHRSTLLFSQGKMYGYVDTLLTMLAMLLKV
                     AMNRAQVCLISSSKSGERHLYLIKVSRDKISDSNDQESANCDAKAIFAVLTSVLTKDD
                     WWNLLLKAIYSLCDLSRFQEAELLVDSSLEYYSFYDDRQKRKELEYFGLSAAILDKNF
                     RKAYNYIRIMVMENVNKPQLWNIFNQVTMHSQDVRHHRFCLRLMLKNPENHALCVLNG
                     HNAFVSGSFKHALGQYVQAFRTHPDEPLYSFCIGLTFIHMASQKYVLRRHALIVQGFS
                     FLNRYLSLRGPCQESFYNLGRGLHQLGLIHLAIHYYQKALELPPLVVEGIELDQLDLR
                     RDIAYNLSLIYQSSGNTGMAQTLLYTYCSI"
     exon            175..286
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            287..483
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            484..607
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            608..799
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            800..965
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1113
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1186
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1187..1290
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1462
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..1665
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1767
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1903
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            1904..2141
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2332
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            2333..2457
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            2458..2610
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     exon            2611..4261
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3017..3022
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="hexamer: AATACA"
     polyA_site      3038
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="major polyA site"
     regulatory      3329..3334
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="hexamer: AATAAA"
     polyA_site      3351
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
     regulatory      3459..3464
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="hexamer: AATAAA"
     polyA_site      3494
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="major polyA site"
     regulatory      3784..3789
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="hexamer: AATATA"
     polyA_site      3801
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
     regulatory      4239..4244
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
                     /note="hexamer: ATTAAA"
     polyA_site      4261
                     /gene="GTF3C3"
                     /gene_synonym="TFIIIC102; TFiiiC2-102; TFIIICgamma"
ORIGIN      
        1 agcttctgga aggcgctgct cttccggttc tctgtcccgg ttcctggggt tgcacagaca
       61 gaccctgtaa acatgtcagg gttcagtccg gaactcatcg actacttgga agggaaaatc
      121 tcctttgagg agttcgaacg gcggagagaa gagagaaaaa cccgcgagaa gaaaagtctt
      181 caggaaaaag gcaagttatc agctgaagaa aatcccgatg actctgaagt tccatcatca
      241 tcaggaatta actctaccaa atcccaagac aaagatgtca atgaaggaga aacatcagat
      301 ggagtgagga agtcagttca caaggtcttt gcttccatgc ttggagagaa tgaagatgat
      361 gaggaggaag aggaagaaga ggaggaggag gaggaggagg aagaaacacc tgagcaaccc
      421 actgcgggcg atgtatttgt attggagatg gttctcaatc gtgaaaccaa gaaaatgatg
      481 aaagagaaaa ggcctcggag taaacttccc agagctctga gaggtctcat gggtgaagcc
      541 aacattcgtt ttgctcgagg agaacgtgaa gaggcgatat tgatgtgcat ggaaatcata
      601 agacaagctc ctctggctta tgagccattc tctactctag ccatgatata tgaggaccaa
      661 ggtgacatgg aaaaatcatt gcagtttgag ttgattgctg cgcatttaaa tcccagtgac
      721 acagaagaat gggttagact ggcagaaatg tctctggaac aagacaatat taagcaggct
      781 attttttgct atacaaaagc tcttaaatat gaacctacta atgtccgtta tctgtgggag
      841 cgatcaagcc tttatgaaca gatgggtgat cataaaatgg ccatggatgg ttataggcgt
      901 attttaaacc ttttgtctcc atctgatggc gaacgtttta tgcagctggc tagagatatg
      961 gcaaagagtt actatgaagc caatgatgtt acttctgcta ttaacataat tgatgaagct
     1021 ttctcaaaac accagggcct agtctccatg gaagatgtta acatagcagc tgaactatat
     1081 atttctaaca aacagtatga caaagctttg gagataatta cagatttttc tggaattgtg
     1141 ctggaaaaaa aaacttcaga agaaggcacc tcagaagaga ataaagctcc tgagaatgtt
     1201 acctgcacta tacctgatgg cgtgccaata gatatcacag tgaagttgat ggtctgcctt
     1261 gtacatctca acattcttga accacttaat cctctcttga caacactagt agaacagaat
     1321 cctgaagata tgggagacct atacctagat gttgctgaag cttttctgga tgttggtgaa
     1381 tataattctg cacttcccct cctcagtgct cttgtttgct ctgaaagata caaccttgca
     1441 gtagtttggc ttcgtcatgc agaatgttta aaggccttag gctatatgga gcgagctgct
     1501 gaaagctatg gcaaggtggt tgatctggcc ccactccatt tggatgcaag gatttcactt
     1561 tctacccttc agcagcagct gggccagcct gagaaagctc tggaagctct ggaaccaatg
     1621 tatgatccag atactttagc acaggatgca aatgctgcac agcaggaact gaagttattg
     1681 cttcatcgtt ctactctgtt gttttcacaa ggcaaaatgt atggttatgt ggatacctta
     1741 cttactatgt tagccatgct tttaaaggta gcaatgaatc gagcccaagt ttgtttgata
     1801 tccagttcca agtctggaga gaggcatctt tatcttatta aagtatcgag agacaaaata
     1861 tcagacagca atgaccaaga gtcagcaaat tgtgatgcaa aagcaatatt tgctgtgctc
     1921 acaagcgtct tgacaaagga tgactggtgg aatcttctgt tgaaggccat atactcctta
     1981 tgtgacctat cccgatttca agaggctgag ttgcttgtag attcctcatt ggaatattac
     2041 tcattttatg atgacaggca aaaacgcaaa gaactagaat actttggtct gtctgctgca
     2101 attctggaca aaaatttcag aaaggcatac aactatatca ggataatggt aatggaaaat
     2161 gtcaataaac cccagctctg gaacattttc aatcaagtta ccatgcactc ccaagatgta
     2221 cgacatcatc gcttctgtct ccgtttgatg ctgaaaaacc cagaaaatca tgccctatgt
     2281 gtcttaaatg gacacaatgc atttgtatct ggtagtttta agcatgcgct tggacagtat
     2341 gtgcaagcct ttcgcactca ccctgacgaa cctctctata gcttctgtat aggcctaacc
     2401 tttattcata tggcatctca gaagtatgtg ttacggagac atgctcttat tgtacagggc
     2461 ttttcctttc ttaatcgata cctcagttta cgtgggccct gccaggaatc attctacaat
     2521 ttgggccgtg gccttcatca gttggggctg attcatcttg caatccacta ttatcagaag
     2581 gccctggagc tccctccact tgtggtagag ggtatagaac ttgaccagtt agacttacga
     2641 agagatattg cctacaactt gtctctcatc tatcagagca gtgggaatac cggaatggct
     2701 caaacgcttt tgtataccta ttgttctata taaagcaccg caactgagaa cagagcaatg
     2761 gcagctgctg tgtgaggacc agtgtcttct gtctcagggc ttattatttg taactccaaa
     2821 atagaaatga caatttcaga attacctaac aaacagtgta tttattttta atatgtgata
     2881 atgatcttgt ggtatatatg caaaattatt cctacaaaaa tttgtatatt ggtctgtcat
     2941 tttcctttca cattctatag tgaattgttc ccaatgttga aatggacgtg taagcctttg
     3001 agctagcttg gagtcgaata cactattttt cactcacacc atttattcat ctttgtattt
     3061 aatactatag ctctgtcaat atcacatgag gcagtttttc aaatacgtat aaacagaggt
     3121 tgcttattat taaaggaaag acaaagtggg actctttatg atgtcatgac catgataact
     3181 aagcacctaa gaaaattatt taaaatagtt atgtggtagg cagaaagaca aataatttag
     3241 ttttttactt ttcaccagca tgtatcttag ctacctaaac tgaaacatgg gaggctgggc
     3301 ttaattcaaa atatattgct ccaaggcaaa taaaaaaatg ctttatctat atttgtggct
     3361 ttctgatgaa aaaatagaga agagcttgtt caataacagg acatggtttc catttcaaga
     3421 tcacaagtaa tataagactg ggcaagtagt acgtatggaa taaaggacat actgctgatt
     3481 gataaagtaa aaaacttttt ttttgtttgt ttactcatct ccactattta ttatatgttc
     3541 ttgaatttaa gttaacagta ctttttagat gatatactgt tagcttaata acaacttttt
     3601 agggaaaaat aaatgctgta attaatgtgc acatgggtta gtaacaccca gcccaattgt
     3661 gggagggaaa caagtagagg cttaggatca aagaaataaa attgggactt attagaaatt
     3721 cttaccactg tttctactgt acacaaaact ttctagttga gcagaatttg tatgcaataa
     3781 gtaaatatat tgtatactcc atgtgtataa tttaaatgca ttttattttt ataattgagg
     3841 ttaactgttt cacatgctta atttttactt tatgccattt ataggtaatg gtagaggtaa
     3901 ctgagataca gtaataagtt agacttgtgt gttggaattc tgtggaactg agcattctgt
     3961 gctccgagtt tctctcttaa attagctcac tggactgtgg ctccagtgtc tactaaatag
     4021 ccgtggagga aataagtctc cctaagggaa aaaaaaacca gctgatattg tatagttttg
     4081 tttagctttt aaaatcatag cttccatttg ctgagttttt actctgctac tgtatgctaa
     4141 gtatggtgct aaacactttg gatatgttat ctctgattct ctcagggaac tgcaaggtag
     4201 ttattattga tattgtcatc accactttgt atctagagat taaatagcat gttcaagatc
     4261 a
//
