LOCUS       NM_015859               6343 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens general transcription factor IIA subunit 1 (GTF2A1),
            transcript variant 1, mRNA.
ACCESSION   NM_015859
VERSION     NM_015859.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6343)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   2  (bases 1 to 6343)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 6343)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   4  (bases 1 to 6343)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 6343)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6343)
  AUTHORS   DeJong,J., Bernstein,R. and Roeder,R.G.
  TITLE     Human general transcription factor TFIIA: characterization of a
            cDNA encoding the small subunit and requirement for basal and
            activated transcription
  JOURNAL   Proc Natl Acad Sci U S A 92 (8), 3313-3317 (1995)
   PUBMED   7724559
REFERENCE   7  (bases 1 to 6343)
  AUTHORS   Ozer,J., Moore,P.A., Bolden,A.H., Lee,A., Rosen,C.A. and
            Lieberman,P.M.
  TITLE     Molecular cloning of the small (gamma) subunit of human TFIIA
            reveals functions critical for activated transcription
  JOURNAL   Genes Dev 8 (19), 2324-2335 (1994)
   PUBMED   7958899
REFERENCE   8  (bases 1 to 6343)
  AUTHORS   Jacob,G.A., Luse,S.W. and Luse,D.S.
  TITLE     Abortive initiation is increased only for the weakest members of a
            set of down mutants of the adenovirus 2 major late promoter
  JOURNAL   J Biol Chem 266 (33), 22537-22544 (1991)
   PUBMED   1939271
REFERENCE   9  (bases 1 to 6343)
  AUTHORS   Ha,I., Lane,W.S. and Reinberg,D.
  TITLE     Cloning of a human gene encoding the general transcription
            initiation factor IIB
  JOURNAL   Nature 352 (6337), 689-695 (1991)
   PUBMED   1876184
REFERENCE   10 (bases 1 to 6343)
  AUTHORS   Conaway,R.C. and Conaway,J.W.
  TITLE     ATP activates transcription initiation from promoters by RNA
            polymerase II in a reversible step prior to RNA synthesis
  JOURNAL   J Biol Chem 263 (6), 2962-2968 (1988)
   PUBMED   2449431
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL136040.5, BC050703.1 and D14887.1.
            
            On Nov 22, 2018 this sequence version replaced NM_015859.3.
            
            Summary: Accurate transcription initiation on TATA-containing class
            II genes involves the ordered assembly of RNA polymerase II
            (POLR2A; MIM 180660) and several general initiation factors
            (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of
            these factors is TFIIA, which when purified from HeLa extracts
            consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul
            2010].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.220546.1,
                                           SRR14038192.905847.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000553612.6/ ENSP00000452454.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 AL136040.5         100437-100443
            8-222               BC050703.1         1-215
            223-365             D14887.1           185-327
            366-1586            D14887.1           329-1549
            1587-6343           AL136040.5         141188-145944
FEATURES             Location/Qualifiers
     source          1..6343
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q31.1"
     gene            1..6343
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /note="general transcription factor IIA subunit 1"
                     /db_xref="GeneID:2957"
                     /db_xref="HGNC:HGNC:4646"
                     /db_xref="MIM:600520"
     exon            1..471
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     CDS             442..1572
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /note="isoform 1 is encoded by transcript variant 1;
                     glucose regulated protein, 58kD pseudogene; general
                     transcription factor IIA, 1, 19/37kDa; TFIIA alpha/beta
                     subunits; transcription initiation factor IIA subunit 1;
                     general transcription factor IIA 1; transcription
                     initiation factor TFIIA 42 kDa subunit"
                     /codon_start=1
                     /product="transcription initiation factor IIA subunit 1
                     isoform 1"
                     /protein_id="NP_056943.1"
                     /db_xref="CCDS:CCDS9873.1"
                     /db_xref="GeneID:2957"
                     /db_xref="HGNC:HGNC:4646"
                     /db_xref="MIM:600520"
                     /translation="MANSANTNTVPKLYRSVIEDVINDVRDIFLDDGVDEQVLMELKT
                     LWENKLMQSRAVDGFHSEEQQLLLQVQQQHQPQQQQHHHHHHHQQAQPQQTVPQQAQT
                     QQVLIPASQQATAPQVIVPDSKLIQHMNASNMSAAATAATLALPAGVTPVQQILTNSG
                     QLLQVVRAANGAQYIFQPQQSVVLQQQVIPQMQPGGVQAPVIQQVLAPLPGGISPQTG
                     VIIQPQQILFTGNKTQVIPTTVAAPTPAQAQITATGQQQPQAQPAQTQAPLVLQVDGT
                     GDTSSEEDEDEEEDYDDDEEEDKEKDGAEDGQVEEEPLNSEDDVSDEEGQELFDTENV
                     VVCQYDKIHRSKNKWKFHLKDGIMNLNGRDYIFSKAIGDAEW"
     exon            472..573
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            574..778
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            779..843
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            844..919
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1053
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1374
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1464
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..6343
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6314..6319
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /note="hexamer: AATAAA"
     polyA_site      6343
                     /gene="GTF2A1"
                     /gene_synonym="TF2A1; TFIIA; TFIIA-42; TFIIAL"
                     /note="major polyA site"
ORIGIN      
        1 gtctctcggc ggcggcggcg gcggcggtgg tggctcgcgc agcttgttgg ctcgctatat
       61 aaaggagaga agcgggcgga ccggacggct ggagctgcag ccggtggcgg cagcggcggc
      121 gcagggagcg gtgaccggtg gtggtttccc tccttggcgc ggggtgggga gcgggcaacg
      181 ccccccggac ccctgaaggg tcgtggcttt tttttttttt ttaaggcgat tctcgaggtt
      241 ttcagctgcg ggaggagtgc ccccctcctc ctcctctctc cgctctcccc tactccttca
      301 ggattgattt tgtttaaaat tttttcccca atcttgcggt gatttgggtc accctccggg
      361 tgttatagtt tttttttttt tggttttgtt tttatcttgt tttcttgggg ttgccccctc
      421 ttgtttgtgt tgtgtgtgga aatggcgaac tcggcaaata caaacaccgt gcctaaatta
      481 tacagatctg tgattgaaga tgtcattaat gatgtgagag acatctttct ggatgatgga
      541 gtggatgaac aagtactgat ggaactaaaa actttatggg aaaacaaact aatgcagtcc
      601 agggcagtag atggatttca ttcagaagag cagcagcttc tactgcaagt tcaacagcag
      661 catcaacccc agcagcagca gcatcaccac catcaccatc atcagcaagc tcagcctcag
      721 cagacagtac ctcagcaagc gcagacccag caggttctta ttcctgcatc acagcaagcc
      781 acagcaccac aagttattgt tccagattct aagttgatac agcatatgaa tgcatcaaac
      841 atgagtgctg ctgctacagc tgctacctta gcactccctg caggtgtgac tcctgttcag
      901 cagatattaa caaattcagg ccagcttctt caggtggtca gagcagccaa tggtgcccaa
      961 tatatctttc agcctcagca gtcagtggtt ctacaacaac aggttatacc acaaatgcag
     1021 cctggtggag tacaagctcc tgttatacag caggtgctgg ctcctcttcc tggagggatt
     1081 tcaccacaga caggtgtcat catccagcct cagcaaatct tatttacagg aaataagact
     1141 caagttatac ctacgacagt ggcagcacct acaccagccc aagcacagat aactgcaact
     1201 ggccagcagc aaccgcaggc ccagcctgct caaacacaag ctccattggt cttacaagtt
     1261 gatggaactg gggatacatc atctgaagaa gatgaagatg aagaagaaga ctatgatgat
     1321 gatgaggagg aagacaaaga gaaagatgga gctgaagatg ggcaggtgga agaagagccc
     1381 ctcaatagtg aagatgatgt gagtgatgag gaaggacagg aactctttga cacagaaaat
     1441 gttgttgtat gccaatatga taagatacac agaagtaaaa acaaatggaa atttcatctc
     1501 aaggatggca ttatgaatct taatggaaga gattatatat tttccaaagc cattggagat
     1561 gcagaatggt gaagagttgc tttttttctt ttataaataa aagaaactta aaaaaaatgt
     1621 aaagcggaca gtttgaaact tggggcatat gccaaccaaa acttcgtttc tgcatgtcag
     1681 aaaagtgcag tagaagcaaa gctactggaa caaagataga ccttgacaac atagacacta
     1741 cttactggca agccatggaa ctgtagcacc tagggttttt gggtgggagg gttggggttt
     1801 tgtgtaggaa aaccataatt gttgatttta aatacaggta cctgccaccg gtaattagca
     1861 tgtaaagctt tgtctatatt ccttcctcca acttgggttc aatcagaaga tacttgttgg
     1921 aatgaactga agaaacttcc cttttgatag attgaactga aactgcttat tgtatgtggt
     1981 tatatttggt aaaagttgcg tgtgagcttt ttacaaaagg gtaagaattg tgttgaattt
     2041 taattcactt gtataagaaa acaatttaaa actctcataa taggtcttaa atatttttac
     2101 ttgctattct ccctcagtga tatatacctc ttcctttcca gctttatgaa acatctattt
     2161 aagatttaaa gttatcagtg atcatagttt ggagataaaa tttgacccag gaatgaatat
     2221 ttattttaat taggttttca tacttattaa atgtaattaa agacttgggt cttgtctgag
     2281 ttcagtggaa ttgaaaccac aactttaatt tccttacaga aaaacttaat ttgtttcttt
     2341 tagtgccaca ccttaaaaag aaaccccaaa ctagctcctc aggaatatag ttttattttg
     2401 caagcatacc atctagctga aattgtatac acatgaatat atgtagactt ttcctgttgg
     2461 gctgaagtgt gtgcttataa atgtgtttag tttttaagct aaacattcag ttaacagtct
     2521 gtgcattgat tagcataggg caggtggtga ggacctggat ttttattaaa cagtttagta
     2581 attataaaag tttcttgtgt ttactagtaa agaattttaa aaatctattc taattcaaca
     2641 agtttttaaa atcaactttg taatttgagg ggaaaatttg gggggaagag gtgggtgggc
     2701 cactaagtta cctctctttc atttggtggc ccttccaggc cattgaaaat aaagacgttg
     2761 gctccagttt gcacattggg aagaaagcat agaaatttga cttgtatatt aaaaataata
     2821 gaaatgtaat atgtatatta agaatgcata ggtctgtatt ctgtaagggg ctctgaagaa
     2881 caatatggca ctgctgtgtt cagtgtgaat tcactgcctg ggagaactgc aggaatgctt
     2941 gtcttcacca ttgtgttctt acaacgaatt caactttcca tggtttatct tgacaaaatt
     3001 tacatgtgtt taggttactt gtatattgat atattttttt aatcttcagt ttttgtcttc
     3061 cttttgcctt tgtgttttca gaagtaacac atgaacactt tttaaagtac attacagaga
     3121 agaaaactgt gagctattat atagtgtttc ttttttaaca caaatctttt aactttaaaa
     3181 aaaggcaaaa attttttttt tctacttccc acccagctta ccaccttgat ctctttaact
     3241 tatgttctaa actttggtgt taatggtggt gtctagcatg ctagtagtta gattttattt
     3301 agatgccata actggtaata cagcttttat tttgactata ttaatttagt tttttgaggg
     3361 gaagtttgtt tattctgtga ctctcaaagc acacagaggt tttaaaatat atattattaa
     3421 gactgagaga agaggaaatg ggagggagta acatcacaga agtgctgttg ttcaactgtt
     3481 cttcaatata gttgctagta ggtttgtatt tactcagtaa ggaagtcagt gacctgaact
     3541 acctataaaa attcagcagt gctgcagtgt tgcttaagtg aaaccctttg gctatctagt
     3601 agtttttatg ctactgaaac ttggattact gtatgatatt cagcttgtct tgggccctct
     3661 atgtagacaa acattcatat tcatagtagt gttgtatact ggcctgtttt tataacttta
     3721 tttttcaaat attaacaacc actgctttca gagtggttat tttgttattt ttgaagcagg
     3781 aaataaccat ttgtatttgc acctgcgtat tgcatatgaa ttatggtata cttggcaaat
     3841 gcttttcttt tacctgtgaa aattctgaaa gctggtccaa gctacattgc ataccaaatt
     3901 gtgctcttat atattatttg catcgtgtcc tttttaatca aatagcatgt tttagtttta
     3961 ttatagtagc ttttgctgta agaatgtcac ttgcttatct tttattgtac ttgaattctt
     4021 aatcatgctt ttaacattgt atttaacaaa tcatttcgta ttaggttcca ttaaaatgtc
     4081 attcctttga aaaggcaagg gatttccact ttcagaattt gaaaatgaaa gtagcatgtt
     4141 tatctaaagg cagaaaatag ttcggacttg gtattatgaa aataagtaat ggtttctgga
     4201 gaggatttgt ttagatttgc acagatggcg atggcacctt ttacttaaat taacattaat
     4261 caacagtgct aaggaaaatt tacacaaaat tacaagataa aacatggaaa tgtgtgcctt
     4321 tcagtataca aactcttgct tggtggccat ttgggtaatc agaccatttg aatgcctgag
     4381 agcatgttta atttctgtgg agtgccacat atggctaaaa caactcttta atgtgcaatt
     4441 aatttctaga gtaaaatgtc tgttatgtga gggggatctt tatgttgggc ttttctattt
     4501 tttaaatgtt cacatttctt tctgttaatt aaaatgccat cataatgtca catttacact
     4561 gttgcctctt ttaaaagcaa agccactttc ttgttctaag attacatcaa gacttgagca
     4621 gtgtgtagta attaaaatgt gtgcttaatg agcataatag attctggttt taggaaataa
     4681 catatagctt ttatatgaat attttctttt gctataatga aagtcacaga tttttttttt
     4741 cctggctttt atggaggaat gaaaagagtt gtctccctct aagagtatac tatttttgat
     4801 tctcatagca ataatgtcac cattcttatc agagggtaaa taccccttgt ataggaaaac
     4861 agacataatt tcctcttggg agttctcttt atgacttagc attttcttct acttgagaaa
     4921 attcctgttt ttccgattat ttcatcttga actttctttt ttttaagctt ttgtgcaatg
     4981 taatagtttg ttgatccatc tttgtacatt ttcattttat ttcatgtctt tctctcacct
     5041 acctgtcaga atcagctata gcagattttg aattctttag ttaaaaaata gttgctttac
     5101 ttgtttcctc atgagtttgt taaatagctt tgcattttag tcctctatta tgctatgaaa
     5161 attattacga agtttatatt gttccctttt taagcctgcc ttactcttgt cttttgtcat
     5221 tgtctatggt ttaatgaaga acacaccaaa ctaacatttt tgtttatttt gaggaacaaa
     5281 aaaacttttc tcttttaagg gaagttacta cacattgagt tagtaactac tctttcagtc
     5341 aaggttcctt aatcagtcca gtctacatca ggactatgac ttggggggcg gggctaatcc
     5401 tttttgctgt tctgagctac tattgtcaac tgctgttgta catactgtta tgtgtaatgg
     5461 cgtaaatata tttattatgt ttgtaaaatt cattgcagat caaggttgct cttctgtgat
     5521 atatgggata ttatgtttta aagaccatct tggaatacaa ttagagaact tagtattttg
     5581 atgtactaag acctatttta agtttaatat tctactttgc aaaaacttta attaaagatg
     5641 ttatttaaaa aaaaatgttg cttgctttgc ttactagtat atggcattgt tatagataat
     5701 tgaataaaat acaatttaga aaggaaaatg ctttacattg ttaatgagaa ttccatttaa
     5761 caacaacaaa aagatgctaa attctgtacc ttaaagataa gtagattgag atgtcaattt
     5821 gaattagtaa actgtgttac aaatgattaa tactagcttt taaaaagttg tattttccag
     5881 gcacacagga atttaggttg ggcgaattca cactaacaaa ttataactaa aaattggtat
     5941 aattaacatt gtttttcaaa ataaagatta ctccttgtga aatattaata attaacatat
     6001 tgtattaaat aagtatttct actccaaagt atagattact taggataaaa acattgttat
     6061 ttctctgttt agtcaaacca cttcctctta gttcagaggt tataaataat tgcatattag
     6121 gagaattgga ttactgaggt ttgtattgcg tattgaatat attttgtgtt attttagaag
     6181 ataataatta gcaggtattt taattttata gttaattcag ctgaatcatt aagaagctcg
     6241 cctttttgta tttttttatc ctgttaacag actatctaga aaacatgcaa attttaacta
     6301 ttaacataat cataataaag atatcttatt tattgccagc aaa
//
