LOCUS       NM_183239               6715 bp    mRNA    linear   PRI 01-OCT-2024
DEFINITION  Homo sapiens glutathione S-transferase omega 2 (GSTO2), transcript
            variant 1, mRNA.
ACCESSION   NM_183239 XM_058395
VERSION     NM_183239.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6715)
  AUTHORS   Liu,C., Tian,W. and Lei,D.
  TITLE     GSTO2 ameliorates human neuroblastoma cell apoptosis, inflammation,
            ferroptosis, and oxidative stress by upregulating GPX4 expression
            in intracerebral hemorrhage
  JOURNAL   Drug Dev Res 85 (6), e22245 (2024)
   PUBMED   39154227
  REMARK    GeneRIF: GSTO2 ameliorates human neuroblastoma cell apoptosis,
            inflammation, ferroptosis, and oxidative stress by upregulating
            GPX4 expression in intracerebral hemorrhage.
REFERENCE   2  (bases 1 to 6715)
  AUTHORS   Simic,P., Coric,V., Pljesa,I., Savic-Radojevic,A., Zecevic,N.,
            Kocic,J., Simic,T., Pazin,V. and Pljesa-Ercegovac,M.
  TITLE     The Role of Glutathione Transferase Omega-Class Variant Alleles in
            Individual Susceptibility to Ovarian Cancer
  JOURNAL   Int J Mol Sci 25 (9), 4986 (2024)
   PUBMED   38732205
  REMARK    GeneRIF: The Role of Glutathione Transferase Omega-Class Variant
            Alleles in Individual Susceptibility to Ovarian Cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6715)
  AUTHORS   Pavlovic,D., Ristic,S., Djukanovic,L., Matic,M., Kovacevic,M.,
            Pljesa-Ercegovac,M., Hadzi-Djokic,J., Savic-Radojevic,A. and
            Djukic,T.
  TITLE     The GSTO2 (rs156697) Polymorphism Modifies Diabetic Nephropathy
            Risk
  JOURNAL   Medicina (Kaunas) 59 (1), 164 (2023)
   PUBMED   36676788
  REMARK    GeneRIF: The GSTO2 (rs156697) Polymorphism Modifies Diabetic
            Nephropathy Risk.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6715)
  AUTHORS   Sobot,V., Stamenkovic,M., Simic,T., Jerotic,D., Djokic,M.,
            Jaksic,V., Bozic,M., Milic,J., Savic-Radojevic,A. and Djukic,T.
  TITLE     Association of GSTO1, GSTO2, GSTP1, GPX1 and SOD2 polymorphism with
            primary open angle glaucoma
  JOURNAL   Exp Eye Res 214, 108863 (2022)
   PUBMED   34826418
  REMARK    GeneRIF: Association of GSTO1, GSTO2, GSTP1, GPX1 and SOD2
            polymorphism with primary open angle glaucoma.
REFERENCE   5  (bases 1 to 6715)
  AUTHORS   Sumiya,R., Terayama,M., Hagiwara,T., Nakata,K., Sekihara,K.,
            Nagasaka,S., Miyazaki,H., Igari,T., Yamada,K. and Kawamura,Y.I.
  TITLE     Loss of GSTO2 contributes to cell growth and mitochondria function
            via the p38 signaling in lung squamous cell carcinoma
  JOURNAL   Cancer Sci 113 (1), 195-204 (2022)
   PUBMED   34726807
  REMARK    GeneRIF: Loss of GSTO2 contributes to cell growth and mitochondria
            function via the p38 signaling in lung squamous cell carcinoma.
REFERENCE   6  (bases 1 to 6715)
  AUTHORS   Ozturk,A., Desai,P.P., Minster,R.L., Dekosky,S.T. and Kamboh,M.I.
  TITLE     Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10
            are not associated with age-at-onset of Alzheimer's disease
  JOURNAL   Neurobiol Aging 26 (8), 1161-1165 (2005)
   PUBMED   15917099
  REMARK    GeneRIF: no association either with age-at-onset in AD cases or
            with disease risk in the case-control cohort but haplotype analysis
            revealed a modest association of one haplotype with AD risk (p =
            0.04)
            GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 6715)
  AUTHORS   Wang,L., Xu,J., Ji,C., Gu,S., Lv,Y., Li,S., Xu,Y., Xie,Y. and
            Mao,Y.
  TITLE     Cloning, expression and characterization of human glutathione
            S-transferase Omega 2
  JOURNAL   Int J Mol Med 16 (1), 19-27 (2005)
   PUBMED   15942673
  REMARK    GeneRIF: molecular cloning; GSTO2 was ubiquitously expressed at a
            low level, with a higher expression in pancreas and prostate
REFERENCE   8  (bases 1 to 6715)
  AUTHORS   Whitbread,A.K., Mellick,G.D., Silburn,P.A., Le Couteur,D.G. and
            Board,P.G.
  TITLE     Glutathione transferase Omega class polymorphisms in Parkinson
            disease
  JOURNAL   Neurology 62 (10), 1910-1911 (2004)
   PUBMED   15159516
  REMARK    GeneRIF: Our results do not confirm an association between PD and
            frequency of the polymorphisms investigated: hGSTO1*A140D, &
            hGSTO1*E155del.
REFERENCE   9  (bases 1 to 6715)
  AUTHORS   Arning,L., Jagiello,P., Wieczorek,S., Saft,C., Andrich,J. and
            Epplen,J.T.
  TITLE     Glutathione S-Transferase Omega 1 variation does not influence age
            at onset of Huntington's disease
  JOURNAL   BMC Med Genet 5, 7 (2004)
   PUBMED   15040808
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
            Publication Status: Online-Only
REFERENCE   10 (bases 1 to 6715)
  AUTHORS   Whitbread,A.K., Tetlow,N., Eyre,H.J., Sutherland,G.R. and
            Board,P.G.
  TITLE     Characterization of the human Omega class glutathione transferase
            genes and associated polymorphisms
  JOURNAL   Pharmacogenetics 13 (3), 131-144 (2003)
   PUBMED   12618591
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC056918.1 and AL162742.9.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_183239.1.
            
            Summary: The protein encoded by this gene is an omega class
            glutathione S-transferase (GST). GSTs are involved in the
            metabolism of xenobiotics and carcinogens. Four transcript variants
            encoding different isoforms have been found for this gene.[provided
            by RefSeq, Jul 2010].
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC056918.1, AK291886.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000338595.7/ ENSP00000345023.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1183              BC056918.1         312-1494
            1184-6715           AL162742.9         25883-31414
FEATURES             Location/Qualifiers
     source          1..6715
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q25.1"
     gene            1..6715
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /note="glutathione S-transferase omega 2"
                     /db_xref="GeneID:119391"
                     /db_xref="HGNC:HGNC:23064"
                     /db_xref="MIM:612314"
     exon            1..86
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            87..351
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             318..1049
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /EC_number="2.5.1.18"
                     /EC_number="1.8.5.1"
                     /EC_number="1.20.4.2"
                     /note="isoform 1 is encoded by transcript variant 1;
                     bA127L20.1 (novel glutathione-S-transferase);
                     glutathione-S-transferase-like protein; GSTO-2; MMA(V)
                     reductase; monomethylarsonic acid reductase; glutathione
                     S-transferase omega 2-2; glutathione-dependent
                     dehydroascorbate reductase"
                     /codon_start=1
                     /product="glutathione S-transferase omega-2 isoform 1"
                     /protein_id="NP_899062.1"
                     /db_xref="CCDS:CCDS7556.1"
                     /db_xref="GeneID:119391"
                     /db_xref="HGNC:HGNC:23064"
                     /db_xref="MIM:612314"
                     /translation="MSGDATRTLGKGSQPPGPVPEGLIRIYSMRFCPYSHRTRLVLKA
                     KDIRHEVVNINLRNKPEWYYTKHPFGHIPVLETSQCQLIYESVIACEYLDDAYPGRKL
                     FPYDPYERARQKMLLELFCKVPHLTKECLVALRCGRECTNLKAALRQEFSNLEEILEY
                     QNTTFFGGTCISMIDYLLWPWFERLDVYGILDCVSHTPALRLWISAMKWDPTVCALLM
                     DKSIFQGFLNLYFQNNPNAFDFGLC"
     exon            352..460
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            461..683
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            684..785
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            786..892
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     exon            893..6715
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1160..1165
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /note="hexamer: AATAAA"
     regulatory      1165..1170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /note="hexamer: AATGAA"
     polyA_site      1183
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /note="major polyA site"
     polyA_site      1195
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
     regulatory      6683..6688
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
                     /note="hexamer: AATAAA"
     polyA_site      6715
                     /gene="GSTO2"
                     /gene_synonym="bA127L20.1; GSTO 2-2"
ORIGIN      
        1 ctccttgctg ctgctgccgc cgccaatcct ggtccggttg cccgagttcc cggaggtctc
       61 tcgcgggacc tctctcaccg ccaccgctcc tactctcggg cttccaaatc tggggcgatg
      121 tctccccagg ttaaattacc ctagctcctg ctccagatcg cttccccgtg ccccgccaga
      181 gcccagtagt tcaaaaatta aatttggggc aaggggtgcg cgccagagcg cagctgtttc
      241 tggagcctgc ggcagcggtg gcgagccaca gggcggcgac cgtgagctcc gggagctgcg
      301 caaaccacct ggagaccatg tctggggatg cgaccaggac cctggggaaa ggaagccagc
      361 ccccagggcc agtcccggag gggctgatcc gcatctacag catgaggttc tgcccctatt
      421 ctcacaggac ccgcctcgtc ctcaaggcca aagacatcag acatgaagtg gtcaacatta
      481 acctgagaaa caagcctgaa tggtactata caaagcaccc ttttggccac attcctgtcc
      541 tggagaccag ccaatgtcaa ctgatctatg aatctgttat tgcttgtgag tacctggatg
      601 atgcttatcc aggaaggaag ctgtttccat atgaccctta tgaacgagct cgccaaaaga
      661 tgttattgga gctattttgt aaggtcccac atttgaccaa ggagtgcctg gtagcgttga
      721 gatgtgggag agaatgcact aatctgaagg cagccctgcg tcaggaattc agcaacctgg
      781 aagagattct tgagtatcag aacaccacct tctttggtgg aacctgtata tccatgattg
      841 attacctcct ctggccctgg tttgagcggc tggatgtgta tgggatactg gactgtgtga
      901 gccacacgcc agccctgcgg ctctggatat cagccatgaa gtgggacccc acagtctgtg
      961 ctcttctcat ggataagagc attttccagg gcttcttgaa tctctatttt cagaacaacc
     1021 ctaatgcctt tgactttggg ctgtgctgag tctcactgtc caccccttcg ctgtccagaa
     1081 ttccccagct tgttgggagt ctacgtcacg gcttgtcttg ggaaccaatc cgtctctctt
     1141 tcttttcttt gaagttccca ataaaatgaa aacaggaaat gtattcttct gataatcatt
     1201 tgtctgactc ctctagcctg tagctgctgc tactgctgct tttttttcct tttttttttt
     1261 gaggcaagat cttgcttcgt tactcaggct ggagtgcagt gggacagtcg gctcactgca
     1321 gccttgaact cctgggctca gttgattctc ccgcctcagc ctcctgagaa gctaggacta
     1381 caggtatgtg tcaccacgcc cagctaattt ttaaaaaaat gttgttgaga cagggtctca
     1441 ctatgttgct caggctggtc tccatctcct ggccgcaagc catccaccca acttggtctc
     1501 caaagtgttg agattacagg catgagccac ctggcctgcc tagcctgtag cttctaacta
     1561 ttttctagaa agtgcctggt gctaatgtca gagcacattt tgggagcctg tgtgcctcct
     1621 aactccttgg ccttcagcct agtttgatct ccagattatt ggtgcagatg ctgatgctga
     1681 ggttcagggt caacctatga ctgatgcttg tcactacaga atggcaccct ccaaagacct
     1741 ccctggtgaa agcttaagaa gagggagaag gaagaagaaa acactccaaa cctaaatacc
     1801 ttccatttgg caaatgaatg tcgctgtcca cgtgggcgag tatgagtgta attctccaaa
     1861 ctttggccat gggcctggag acaccgaggg tcttgtgact ggaaagaatt ccaaagcagg
     1921 aaatgaaaca ccggtttatc acccaggact aactacgtca gaatttcact ggtgctgtca
     1981 gggctcagga tgtctcacaa aatgttctat agccggcatc ctgccttaaa aaaatacaca
     2041 cgccccaaac ccagccacaa gcaaaggtca ttccgttgga tttgcgtcac actctcttcc
     2101 aattcatctc aacaaatgcc tctggttgcc tgttgtgtac caagcccagg ggcacactgg
     2161 ggataaagtt gaaaaagaca ttggctctgt ccctgggagc ccccatctct ccacttatct
     2221 tggttgaggt tttaaaccta gcgctttgga gctgcttgtc tgttgtaggg atgcttgtct
     2281 ctgatgtggc ccctctgcca gcttcgccag gcagtaccac cccactgaag acagcaaaga
     2341 gctgaggatg gctggtgcca acaggtccct tgggctggga gcatctactg cctgcactat
     2401 gggaggggga ccaagtttgt ccaatgctgt ttcatctcag tgtctgagga tcagcctgtg
     2461 atcatttcag ctttgctcat gctggatcct ttcccatcct cctagctgtg ctgagacacc
     2521 aggcagcaac aggagcgatg ttttgccttg tctgtgctcc ctaaggagct gtctgccacc
     2581 tctgcctctg agacagccca aatcagccct cctctctccc cacgtctcag tctggccctg
     2641 ccatctgctg gctctgggta tattttgacc catgtaaata gttaccaggt gttactctgt
     2701 gccagctgga cagaaacaag cctgcttggt gaggtggcca gaacttccag aagaggcagc
     2761 gcatgacagg ggcagtctgc cgcaccatct gctccggatg tggagccctg ttgccatggc
     2821 accctagtta atgctgagtg aggtctgtga atcaccgttt tcctgggatc tttgctccaa
     2881 gaagagggga atcttctcct gtggcctctc ataggactta ggagattgat cagccttttg
     2941 ccggtacaaa tcctgcatgc tagtgagtgc ttgtcataag accaaagtta ccactgatgc
     3001 aacaggaaat ggcatgcctc tggctcacca aaatgaaggt gttctctttt ggggctccgc
     3061 acactaattt agaaagcttg aagaaccagg aattatagaa tggagaaaag cactcatggg
     3121 ggaggtttgc agcctggtgg cctatagccc agtttgggat ttgagtgcct cttggccagg
     3181 catgctccct gctgtttacc agggtcctgg tcacctgcac atccttacac ttcctccatc
     3241 tcgcttcttt gtcacttgtc tgacccacag agaaaactga gttatcaatc tttgaataaa
     3301 actagaagga tgtggcctgg agaaaagagg gaaggaggta attaaataat gctccatgaa
     3361 gaactttaaa aatatgcttc ttaattaata catgtggaaa gaatacatat gggttaaaaa
     3421 tacaataatg taaaagaata gaaaatcttc cattatcttg tgtcctagag ataaccactt
     3481 ttagtaattg gtgtctacct ttttttcccc ttttctttta aataatagag atggggtttc
     3541 gctatgttga ccaggctggt cttgaactcc tggcttcaag tgatcctccc atctcggcat
     3601 cccaaagtgc tgggattata ggtctgagtc atcatgcctg gtgggtgtct atcttataaa
     3661 aagcactaaa cttaaagatt taaaggtgag agcctgtatt aggccattct catggtgcta
     3721 taaagaactg cccaagactg agtaatttat aaaggaaaga ggtttaattg actcacaatt
     3781 ccacatggct ggggaagcct caggaaactt tcaatcatgg tggaagggga agcaaacatg
     3841 tccttctgca caaggtggca gaagagagaa gtacagagcc aaagagggaa aaactcctta
     3901 taaaaccatt agatctcatg agaactcact cactgtcatg agaaaagcat agggaaaaca
     3961 ctcccacaat cgaatcacct cccttgaggt ccctccccca acatgtgggg attataattc
     4021 agattaaaat tgaagatgag attttaggtg gagcacagcc aaaccatatc agagccattc
     4081 tctatctttt gcagattgga aaaataaaaa aattagttta aaccacagca tttaaaagaa
     4141 atggtcatag atgatgttaa catcagaatg gaggttgtgt ggagttcccc tccttggagg
     4201 ttctgagcta cagcctagcc tggactcagt ccagttacaa tctaacatgg ctagggggag
     4261 gagggagcat gatggggcag ggcttgtgtg gctgggacag ctggctatgg tcgtggtgct
     4321 ggtgactaaa tggtacttga aatttctttt agatctaaaa ttctgtgata tggtttggat
     4381 ctgagacccc accaaatttc gtgttgaaat gtaatcccca atgctggtgg gaggtgattg
     4441 gatcatgggg gtagatttct catgaatggt ttagcaccat tctcttggtg ctgttctcat
     4501 gatagtgagt gagttctcat gagttctggt tgtttaaaag tgtgcagcat ctccctgacc
     4561 cctcttgcgc cagctcccac catgggagat gcctcgctcc ccctttgctt tttgccatga
     4621 gaggaagctt cctgagggct ctccagaagc agaatctact acacttctca tacagcctgc
     4681 agaaccatga gccaattaaa cctcttttta aaaacacttt tattttaagt tcaggggtac
     4741 atgtgcagga tgtgcaggtt cgttccatag gtaaacatgc gtcatggggt ttgttatgca
     4801 gattatttca tcacctagat attaagtcta gtatccatta gttatttttc ctgatcctct
     4861 ccctcctccc accctgcacc ctctgatagg cctcagtgtg tattgttacc ctccacatgt
     4921 ccatgtgttc tcatgattta gctcccactt ataagtgaga acatgcagtt tttgtaaacc
     4981 tgttttcttt agggaaagtt tagaattttc tagagactgg ttgtatggtt gtgaccaaaa
     5041 tgccagtagt gatatggaca gtgaaggcca ggctgaggag gtgatggaaa tgaggaactt
     5101 actgggaact ggagcaaagg tcacttttgt tatgctttag caaagaactt ggctgcattg
     5161 tgctcctggc ctagggacct gtggaagttt gaacttgaga gtgatgattt tagggtatct
     5221 ggcagaaaaa atttctaagc agcaaagcat tcaagatgcg ccctggctgc tttcaacaac
     5281 ctatgctcat atttgtgagc aaagaaatta tgttaagttg gaacttatat ttacagggga
     5341 agcagagcgt aaaagtttgg agaatttgca gccagctatg tggtagaaaa gaagagcccg
     5401 ttttcaggga aggaattcaa gcaggctgca gaaatttgca taagtaaaaa ggagccaagt
     5461 gctaatggcc aagaaaatgg ggaaaaggcc ttgaaggcat ttcagagacc tttgtggcag
     5521 cccctcccat cacagactca gaggcctagg aggacagaat gactctgagt attaaagtag
     5581 atttaatcta aatcataaag tacaagctag agcaatccct ccagtgctgc agaaactgcc
     5641 tgcatgtggc tcccacattg tttcttggag ctttggtggt ggtaggggtg gcaggggcag
     5701 gtgttatgtt tcttggtttc tcaccttcag gtctccttac ccatgtttcc tttgtcagag
     5761 tcattggcct tgatggaggg gagactgggt tactctgagt tgagaagcaa gcttgactgc
     5821 cctgtggttt atatcagcct agcttagttt gttttctgaa gtcttcacaa ataaccaaat
     5881 atccagccca gtgcagttct caatgagtag tctccagttc ccatccccca ccacacacac
     5941 acaccaaaca ctgtgcccac ctgggagacc cattttcatt tatcttcttc tttgagtgcc
     6001 tggaaggctg aacatttgat cttttcaaac atttttctct catctggcct gttagcgctc
     6061 ttgagccttt gaaaatgcca tttcctctac atactattct tcctcagagc agccctctgt
     6121 ttttttttcc aaccagtctt ttctcttgca aagttcagat caaaattctt ctttatgtaa
     6181 agagaagtgg cgtgccatag gggttacaaa cagggcttca aggttagcac tgggatcaaa
     6241 ttccgacttt gcaacttaac tttcttgagt aagttgctac acctctatta gcctcagttt
     6301 cttatctgta aaatgggacg gctaagtacc tatttcattg ggctgttgaa taatgatggt
     6361 ctcatctatg caagggctta gtaccagctg ggtgaaactc agtgaatggc aggcaaccct
     6421 attatgacta ggcttctgcc aatgatcaga cttgaaccct gtgctcatcc ccccatcact
     6481 ttgtggaact agatgtccta cgttgcacat ggcttgattc atggtttgga gttgttttct
     6541 ggttgtttcc tgtgtgcagg tttaatctca acctgtgatc ccttgaaagc tgcaatttta
     6601 tccctccccg tcctcctccc tctcacccca aggccaagtt taatactgtg cattctgaaa
     6661 tcttgcaatg ttgatgatgt aaaataaatc ttctctcctg tgtttctgaa gaata
//
