LOCUS       XM_011513452            2525 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens G protein-coupled receptor kinase 4 (GRK4),
            transcript variant X8, mRNA.
ACCESSION   XM_011513452
VERSION     XM_011513452.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011513452.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2525
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..2525
                     /gene="GRK4"
                     /gene_synonym="GPRK2L; GPRK4; GRK4a; IT11"
                     /note="G protein-coupled receptor kinase 4; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 18 ESTs, 4 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 6 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:2868"
                     /db_xref="HGNC:HGNC:4543"
                     /db_xref="MIM:137026"
     CDS             501..2198
                     /gene="GRK4"
                     /gene_synonym="GPRK2L; GPRK4; GRK4a; IT11"
                     /codon_start=1
                     /product="G protein-coupled receptor kinase 4 isoform X8"
                     /protein_id="XP_011511754.1"
                     /db_xref="GeneID:2868"
                     /db_xref="HGNC:HGNC:4543"
                     /db_xref="MIM:137026"
                     /translation="MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSE
                     LRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCG
                     LSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFE
                     EYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEQSPVGCAVDGSWKKQQPN
                     VDDTEARGPEPEAHDTIFSTFVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKR
                     ILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAE
                     LCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYM
                     APEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSE
                     KFSEDAKSICRMPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNE
                     MIESGCFKDINKSESEEALPLDLDKNIHTPVSRPNRGFFYRLFRRGAVLYSLRATWC"
ORIGIN      
        1 gtagtgcccc ggccgcggcg gcgaggggcg ctccctcttc agctaagccg ttagcgccga
       61 gcccgcccgg gagcgggtcg ccggccgcgg cgggcgcccc tgccagtgag cccctgtccg
      121 aagtgagcca cggcattgac tcggggctgc ccgggggcag ggcactgagg agggagttgc
      181 gcgcgcgagg cgagggcgat ggggccaaga agaaccgggg cgatagcgcg gcagcggtga
      241 cagctgggac ccgccgcggt cgggctgccc cctcccctcg ccccgaccgc tcccctgctg
      301 gtgagggcct gcggaggcgg cggcggcggc gcccttggtg gcagtggtgg cggcggagca
      361 gcctcccggg atcgtgtccg gagctcgagg agagggtggt gcccggcgag ctatgcacgg
      421 gggcggcggc gtctcctcct gttccgcctc ctcagtctcc tcggtctcgc agaatccgcc
      481 ggcggcggcg gcgccaggac atggagctcg agaacatcgt ggccaactcg ctgctgctga
      541 aagcgcgtca aggaggatat ggcaaaaaaa gtggtcgtag taaaaaatgg aaggagatac
      601 tgacactgcc tcctgtcagc cagtgcagtg agcttagaca ttccattgaa aaggattata
      661 gcagtctttg tgacaagcaa ccgataggaa gacgtctctt caggcagttc tgtgatacca
      721 aacccactct aaagaggcac attgaattct tggatgcagt ggcagaatat gaagttgccg
      781 atgatgagga ccgaagtgat tgtggactgt caatcttaga tagattcttc aatgataagt
      841 tggcagcccc tttaccagaa atacctccag atgttgtgac agaatgtaga ttgggactga
      901 aggaggagaa cccttccaaa aaagcctttg aggaatgtac tagagttgcc cataactacc
      961 taagagggga accatttgaa gaataccaag aaagctcata tttttctcag tttttacaat
     1021 ggaaatggct ggaaaggcaa cccgtaacaa agaacacatt tagacattac agagttctag
     1081 gaaaaggcgg atttggagag cagtcccctg tggggtgtgc agtggatggg agttggaaga
     1141 aacagcagcc taatgttgat gacacagagg cacggggacc agaacctgag gctcatgata
     1201 ctattttttc cacttttgtt tgcgcctgtc aagtgcgagc cacaggaaaa atgtatgcct
     1261 gcaaaaagct acaaaaaaaa agaataaaga agaggaaagg tgaagctatg gctctaaatg
     1321 agaaaagaat tctggagaaa gtgcaaagta gattcgtagt tagtttagcc tacgcttatg
     1381 aaaccaaaga tgccttgtgc ttggtgctca ccattatgaa tggaggggat ttgaagtttc
     1441 acatttacaa cctgggcaat cccggctttg atgagcagag agccgttttc tatgctgcag
     1501 agctgtgttg cggcttggaa gatttacaga gggaaagaat tgtatacaga gacttgaagc
     1561 ctgagaatat tctccttgat gatcgtggac acatccggat ttcagacctc ggtttggcca
     1621 cagagatccc agaaggacag agggttcgag gaagagttgg aacagtcggc tacatggcac
     1681 ctgaagttgt caataatgaa aagtatacgt ttagtcccga ttggtgggga cttggctgtc
     1741 tgatctatga aatgattcag ggacattctc cattcaaaaa atacaaagag aaagtcaaat
     1801 gggaggaggt cgatcaaaga atcaagaatg ataccgagga gtattctgag aagttttcag
     1861 aggatgccaa atctatctgc aggatgcctc atgccgttta ctgtaaggac gtcctggata
     1921 tcgagcagtt ctcggtggtg aaagggatct acctggacac cgcagatgaa gacttctatg
     1981 ctcggtttgc taccgggtgt gtctccatcc cctggcagaa tgagatgatc gaatctgggt
     2041 gtttcaaaga catcaacaaa agtgaaagtg aggaagcttt gccattagat ctagacaaga
     2101 acatacatac cccggtttcc agaccaaaca gaggcttctt ctatagactc ttcagaagag
     2161 gggcagtttt atacagtctg agagccacat ggtgctaggt ggaggccagc cagaacaatg
     2221 agaacaccct cgcagtgagg tttgttgctg ggatgaagac tgttctgatc caaaacagga
     2281 ctaccttcca gcatttacaa acaggttccc gtgtcgctga caaaatagtt tacactgggc
     2341 tcagaaatcg gcatcctgtg gaaccttcgt cagatggcac tcacagtgca tctctccctg
     2401 ctctggctct tagactcacc tccttcgccc gctgcacggg gaaagtggat tcctttttga
     2461 aaagggaatc ctggctgggt gcggtggctc acgcctgtaa tcccagcact ttgggaggcc
     2521 gaggc
//
