LOCUS       XM_005266946            4677 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens glutamate ionotropic receptor kainate type
            subunit 2 (GRIK2), transcript variant X3, mRNA.
ACCESSION   XM_005266946
VERSION     XM_005266946.5
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005266946.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4677
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..4677
                     /gene="GRIK2"
                     /gene_synonym="EAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6;
                     NEDLAS"
                     /note="glutamate ionotropic receptor kainate type subunit
                     2; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 10 ESTs, 275 long SRA reads, 12
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 3 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:2898"
                     /db_xref="HGNC:HGNC:4580"
                     /db_xref="MIM:138244"
     CDS             526..3105
                     /gene="GRIK2"
                     /gene_synonym="EAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6;
                     NEDLAS"
                     /codon_start=1
                     /product="glutamate receptor ionotropic, kainate 2 isoform
                     X3"
                     /protein_id="XP_005267003.1"
                     /db_xref="GeneID:2898"
                     /db_xref="HGNC:HGNC:4580"
                     /db_xref="MIM:138244"
                     /translation="MGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASK
                     KACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYP
                     DFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTK
                     DAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVE
                     PYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYD
                     AVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGL
                     RTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEE
                     PYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWN
                     GMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLN
                     PLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFG
                     VGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADD
                     LAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTS
                     DYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEG
                     KLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSK
                     KNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKE
                     TMA"
ORIGIN      
        1 cattttagga agttttgtat attttgcctg actgaaattt tgcagaaaac tactagtttg
       61 tagtggaaca ggcaagggtt ttgaagtcag gcatgagcag attctactag tggctctatc
      121 acttgatagc tatgtgatct ttgaccagag gggtaattcc tgtaaaataa tgctattttg
      181 gatggctttg aaggttcatt gtgacctcaa atacttgttg agtgcttact ctgtgacagc
      241 cactctaaat gttttgtaca tgctaacatt tattctttat tgcaattcta tgcagtaacc
      301 tcccttgtca ttcttctttc agagatgagg cagctcagac tgaggtttta agcaactgcc
      361 caaaattata cagatagcaa ttggcaaatc cagaatgtta aacccggtct agctccaaat
      421 aaatgttata tataagggta gagagtaaag aagaatacca ctgttcttct ccacatacac
      481 agaaggaatc taggtggtat ttttgaatat gtggaatctg gcccaatggg agctgaggaa
      541 cttgcattca gatttgctgt gaacacaatt aacagaaaca gaacattgct acccaatact
      601 acccttacct atgataccca gaagataaac ctttatgata gttttgaagc atccaagaaa
      661 gcctgtgatc agctgtctct tggggtggct gccatcttcg ggccttcaca cagctcatca
      721 gcaaacgcag tgcagtccat ctgcaatgct ctgggagttc cccacataca gacccgctgg
      781 aagcaccagg tgtcagacaa caaagattcc ttctatgtca gtctctaccc agacttctct
      841 tcactcagcc gtgccatttt agacctggtg cagtttttca agtggaaaac cgtcacggtt
      901 gtgtatgatg acagcactgg tctcattcgt ttgcaagagc tcatcaaagc tccatcaagg
      961 tataatcttc gactcaaaat tcgtcagtta cctgctgata caaaggatgc aaaaccctta
     1021 ctaaaagaaa tgaaaagagg caaggagttt catgtaatct ttgattgtag ccatgaaatg
     1081 gcagcaggca ttttaaaaca ggcattagct atgggaatga tgacagaata ctatcattat
     1141 atctttacca ctctggacct ctttgctctt gatgttgagc cctaccgata cagtggtgtt
     1201 aacatgacag ggttcagaat attaaataca gaaaataccc aagtctcctc catcattgaa
     1261 aagtggtcga tggaacgatt gcaggcacct ccgaaacccg attcaggttt gctggatgga
     1321 tttatgacga ctgatgctgc tctaatgtat gatgctgtgc atgtggtgtc tgtggccgtt
     1381 caacagtttc cccagatgac agtcagttcc ttgcagtgta atcgacataa accctggcgc
     1441 ttcgggaccc gctttatgag tctaattaaa gaggcacatt gggaaggcct cacaggcaga
     1501 ataactttca acaaaaccaa tggcttgaga acagattttg atttggatgt gatcagtctg
     1561 aaggaagaag gtctagaaaa gattggaacg tgggatccag ccagtggcct gaatatgaca
     1621 gaaagtcaaa agggaaagcc agcgaacatc acagattcct tatccaatcg ttctttgatt
     1681 gttaccacca ttttggaaga gccttatgtc ctttttaaga agtctgacaa acctctctat
     1741 ggtaatgatc gatttgaagg ctattgcatt gatctcctca gagagttatc tacaatcctt
     1801 ggctttacat atgaaattag acttgtggaa gatgggaaat atggagccca ggatgatgcc
     1861 aatggacaat ggaatggaat ggttcgtgaa ctaattgatc ataaagctga ccttgcagtt
     1921 gctccactgg ctattaccta tgttcgagag aaggtcatcg acttttccaa gccctttatg
     1981 acacttggaa taagtatttt gtaccgcaag cccaatggta caaacccagg cgtcttctcc
     2041 ttcctgaatc ctctctcccc tgatatctgg atgtatattc tgctggctta cttgggtgtc
     2101 agttgtgtgc tctttgtcat agccaggttt agtccttatg agtggtataa tccacaccct
     2161 tgcaaccctg actcagacgt ggtggaaaac aattttacct tgctaaatag tttctggttt
     2221 ggagttggag ctctcatgca gcaaggttct gagctcatgc ccaaagcact gtccaccagg
     2281 atagtgggag gcatttggtg gtttttcaca cttatcatca tttcttcgta tactgctaac
     2341 ttagccgcct ttctgacagt ggaacgcatg gaatccccta ttgactctgc tgatgattta
     2401 gctaaacaaa ccaagataga atatggagca gtagaggatg gtgcaaccat gacttttttc
     2461 aagaaatcaa aaatctccac gtatgacaaa atgtgggcct ttatgagtag cagaaggcag
     2521 tcagtgctgg tcaaaagtaa tgaagaagga atccagcgag tcctcacctc tgattatgct
     2581 ttcctaatgg agtcaacaac catcgagttt gttacccagc ggaactgtaa cctgacacag
     2641 attggcggcc ttatagactc taaaggttat ggcgttggca ctcccatggg ttctccatat
     2701 cgagacaaaa ttaccatagc aattcttcag ctgcaagagg aaggcaaact gcatatgatg
     2761 aaggagaaat ggtggagggg caatggttgc ccagaagagg agagcaaaga ggccagtgcc
     2821 ctgggggttc agaatattgg tggcatcttc attgttctgg cagccggctt ggtgctttca
     2881 gtttttgtgg cagtgggaga atttttatac aaatccaaaa aaaacgctca attggaaaag
     2941 aggtccttct gtagtgccat ggtagaagaa ttgaggatgt ccctgaagtg ccagcgtcgg
     3001 ttaaaacata agccacaggc cccagttatt gtgaaaacag aagaagttat caacatgcac
     3061 acatttaacg acagaaggtt gccaggtaaa gaaaccatgg cataaagctg ggaggccaaa
     3121 cacccaagca caaactgtcg tctttttcca aacaatttag ccagaatgtt tcctgtggaa
     3181 atatgcaacc tgtgcaaaat aaaatgagtt acctcatgcc gctgtgtcta tgaactagag
     3241 actctgtgat ctaagcagtt gcaatgatca gacttgattt acaagcatca tggatcaacc
     3301 aagttacacg gggttacact gttaatcatg ggttcctccc ttcttctgag tgaatgttaa
     3361 catgcgcatt ttgtggctga tttcaaatgc agtccagtga gaaattacag gttccttttg
     3421 aagctcaact gttgccagga gatggaatat caatgcccaa cagggcaacc aataaaagtg
     3481 tcactaagaa tataaatatt tggaatcagc aaaaactgta gtgttacagg aaacagtaca
     3541 gtcttctgaa cacccagatc atagaggtga tgatgttact agcccccaac tactcagtat
     3601 aattattgtc tgaatgcaaa gtatgtgttt ataggatgtg aaaaaatgta atgcaaaaca
     3661 aatttgaatc ccatggcagt tggaatataa agcagatgtt catcacttat tttccttttt
     3721 tcttttctta tttttttttt tgacagtctg tgtcactgat tgagatagaa atgccaatta
     3781 tcaaggaaat aatgttttct taagttccct aaggcagaag atttaacatg caattctacc
     3841 agatcccttc ctattccccc aacacctttt ctctaacccc catatcccaa ataataataa
     3901 taataataat aataataata ataataataa taaaagcagt tggttcagtg attctgaatt
     3961 aaaaggataa tgttttgcaa tgttcaagtt gtaaaaactg gccgagtatt ggctgtgtgg
     4021 aagactaaag ctttcattct aacattcaga catagcaatc caaacccttg ttcctgctgt
     4081 aaatgaactt gatggagcat gggcagattt cagtgatacg agaaagggga ctggtcatct
     4141 atagaaaaat ctgtgagaga acttggaagt ggactgcgtt tatcaataca gtcacaatgt
     4201 taaatgaaca aaattcttga acagtttttt ttcaaaaaat gttcaggttt atttgtggaa
     4261 atgcaagatt tctatgaaaa tagtttttgt atggaaattt ttgtaatact ttttatcaac
     4321 aaaacaagaa catgtgttcc tgtcaggggt gtgatgtcaa gcatgaatgg tagtgcgtgt
     4381 gcaccaccaa cgtttggtga aaactatttt tatcaagaaa aaaggaatca tagaagagaa
     4441 atattttcaa gttagataat ataaaagcta ggtgcactac caccactgct taccatgcca
     4501 cacccctggt ttccacgagg ctgacaacat actgtaatga acaattgtgt gtaaaatggt
     4561 aaaagacaca gacctcttga caacattgtg ataacagttg agtgcacaca gtttgctgtt
     4621 tgaatccaat gcacaaaatt aaaaaaaatc attaaaacta tgttcatttt actttca
//
