LOCUS       XM_047440744            2573 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens glutamate ionotropic receptor kainate type
            subunit 1 (GRIK1), transcript variant X1, mRNA.
ACCESSION   XM_047440744
VERSION     XM_047440744.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000021.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2573
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="21"
     gene            1..2573
                     /gene="GRIK1"
                     /gene_synonym="EAA3; EEA3; GLR5; GluK1; gluR-5; GLUR5"
                     /note="glutamate ionotropic receptor kainate type subunit
                     1; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 mRNA, 35 ESTs, 7 long SRA reads, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 1 sample with
                     support for all annotated introns"
                     /db_xref="GeneID:2897"
                     /db_xref="HGNC:HGNC:4579"
                     /db_xref="MIM:138245"
     CDS             497..2440
                     /gene="GRIK1"
                     /gene_synonym="EAA3; EEA3; GLR5; GluK1; gluR-5; GLUR5"
                     /codon_start=1
                     /product="glutamate receptor ionotropic, kainate 1 isoform
                     X1"
                     /protein_id="XP_047296700.1"
                     /db_xref="GeneID:2897"
                     /db_xref="HGNC:HGNC:4579"
                     /db_xref="MIM:138245"
                     /translation="MEHGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFE
                     TVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLAL
                     GVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRA
                     ILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKE
                     MKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVN
                     MTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIA
                     SHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDI
                     ISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLI
                     VTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQN
                     DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPG
                     VFSFLNPLSPDIWMYVLLACLGVSCVLFVIARIRADAQSSIDQNSWRDMVVFHPNHHF
                     ILHGQSGCLLDSRENGIPHRFGR"
     polyA_site      2573
                     /gene="GRIK1"
                     /gene_synonym="EAA3; EEA3; GLR5; GluK1; gluR-5; GLUR5"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agttaacctg ctggagctca tcaggcttgc tcagagcccc tgcaccaact caccctgtac
       61 cctctctcct tcttcgttag tcttctttcc cccttttccc tcctctgtct gtgcctatcc
      121 cccgactttt gcatctgacc aaaggacgaa tgagggagac gttcctgcag atcggggcag
      181 caactttcct cagctggtct ctgggctccg ggagccagag agcgctgatc ctccgcggtc
      241 tgcggcccat ggaagaggag gaggaggagc cgtgatgggc tagcgacagc actgaggagc
      301 cccgagagag ctcagccttg ccagccagct ccgcggtccc acgcgggttc cctcgagctc
      361 gctccgtggg gagcgcgcag cgtgcttgga accggagcat ccagagagga tgaggcgggg
      421 acccggccca agttgggtgc atctctcggg cgtccggcag cggctgtatc tcggcatgaa
      481 ttaagaagct aggaagatgg agcacggcac actcctcgcc cagcccgggc tctggaccag
      541 ggacaccagc tgggcactcc tctatttcct ctgctatatc ctccctcaga ccgccccgca
      601 agtactcagg atcggaggga tttttgaaac agtggaaaat gagcctgtta atgttgaaga
      661 attagctttc aagtttgcag tcaccagcat taacagaaac cgaaccctga tgcctaacac
      721 cacattaacc tatgacatcc agagaattaa cctttttgat agttttgaag cctcgcggag
      781 agcatgtgac cagctggctc ttggtgtggc tgctctcttt ggcccttccc atagctcctc
      841 cgtcagtgct gtgcagtcta tttgcaatgc tctcgaagtt ccacacatac agacccgctg
      901 gaaacacccc tcggtggaca acaaagattt gttttacatc aacctttacc cagattatgc
      961 agctatcagc agggcgatcc tggatctggt cctctattac aactggaaaa cagtgacagt
     1021 ggtgtatgaa gacagcacag gtctaattcg tctacaagag ctcatcaaag ctccctccag
     1081 atataatatt aaaatcaaaa tccgccagct gccctctggg aataaagatg ccaagccttt
     1141 actcaaggag atgaagaaag gcaaggagtt ctatgtgata tttgattgtt cacatgaaac
     1201 agccgctgaa atccttaagc agattctgtt catgggcatg atgaccgagt actatcacta
     1261 ctttttcaca accctggact tatttgcttt ggatctggaa ctctataggt acagtggcgt
     1321 aaacatgacc gggtttcggc tgcttaacat tgacaaccct cacgtgtcat ccatcattga
     1381 gaagtggtcc atggagagac tgcaggcccc acccaggccc gagactggcc ttttggatgg
     1441 catgatgaca actgaagcgg ctctgatgta cgatgctgtg tacatggtgg ccattgcctc
     1501 gcaccgggca tcccagctga ccgtcagctc cctgcagtgc catagacata agccatggcg
     1561 cctcggaccc agatttatga acctgatcaa agaggcccgg tgggatggct tgactgggca
     1621 tatcaccttt aataaaacca atggcttgag gaaggatttt gatctggaca ttattagtct
     1681 caaagaggaa ggaactgaaa aggctgctgg cgaagtgtct aaacacttgt ataaagtgtg
     1741 gaagaagatt gggatttgga attccaacag tgggcttaac atgacggaca gcaacaaaga
     1801 caagtccagc aatatcactg attcattggc caacagaaca ctcattgtca ccaccattct
     1861 ggaagaaccc tatgttatgt acaggaaatc tgataagcct ctatatggaa atgacagatt
     1921 tgaaggatat tgcctagacc tgttgaaaga attgtcaaac atcctgggtt tcatttatga
     1981 tgttaaacta gttcccgatg gcaaatatgg ggcccagaat gacaaagggg agtggaacgg
     2041 gatggttaaa gaactcatag atcacagggc tgacctggca gtggctcctc ttaccatcac
     2101 ctacgtgcgg gagaaagtca ttgacttctc caaacccttc atgaccctag gcatcagcat
     2161 tctctaccgg aagcccaatg gtaccaatcc aggcgttttc tccttcctca accccctgtc
     2221 tccagatatt tggatgtatg tgctcttagc ctgcttggga gtcagctgtg tactctttgt
     2281 gattgcaagg atcagagctg atgcccaaag ctctatcgac cagaatagtt ggagggatat
     2341 ggtggttttt caccctaatc atcatttcat cctacacggc caatctggct gccttcttga
     2401 cagtagagag aatggaatcc cccatagatt cggcagatga tctggcaaag caaaccaaga
     2461 tagaatatgg ggcggttaga gatggatcaa caatgacctt cttcaaggta agaagctgac
     2521 aaagtgttct cagtgattat ctgatacttg tggtagagta taaaagaatc tgt
//
