LOCUS       NM_017551               6154 bp    mRNA    linear   PRI 06-DEC-2024
DEFINITION  Homo sapiens glutamate ionotropic receptor delta type subunit 1
            (GRID1), mRNA.
ACCESSION   NM_017551 XM_043613
VERSION     NM_017551.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6154)
  AUTHORS   Allen,J.P., Garber,K.B., Perszyk,R., Khayat,C.T., Kell,S.A.,
            Kaneko,M., Quindipan,C., Saitta,S., Ladda,R.L., Hewson,S.,
            Inbar-Feigenberg,M., Prasad,C., Prasad,A.N., Olewiler,L., Mu,W.,
            Rosenthal,L.S., Scala,M., Striano,P., Zara,F., McCullock,T.W.,
            Jauss,R.T., Lemke,J.R., MacLean,D.M., Zhu,C., Yuan,H., Myers,S.J.
            and Traynelis,S.F.
  TITLE     Clinical features, functional consequences, and rescue pharmacology
            of missense GRID1 and GRID2 human variants
  JOURNAL   Hum Mol Genet 33 (4), 355-373 (2024)
   PUBMED   37944084
  REMARK    GeneRIF: Clinical features, functional consequences, and rescue
            pharmacology of missense GRID1 and GRID2 human variants.
REFERENCE   2  (bases 1 to 6154)
  AUTHORS   Piot,L., Heroven,C., Bossi,S., Zamith,J., Malinauskas,T.,
            Johnson,C., Wennagel,D., Stroebel,D., Charrier,C., Aricescu,A.R.,
            Mony,L. and Paoletti,P.
  TITLE     GluD1 binds GABA and controls inhibitory plasticity
  JOURNAL   Science 382 (6677), 1389-1394 (2023)
   PUBMED   38060673
REFERENCE   3  (bases 1 to 6154)
  AUTHORS   Herbrechter,R., Hube,N., Buchholz,R. and Reiner,A.
  TITLE     Splicing and editing of ionotropic glutamate receptors: a
            comprehensive analysis based on human RNA-Seq data
  JOURNAL   Cell Mol Life Sci 78 (14), 5605-5630 (2021)
   PUBMED   34100982
REFERENCE   4  (bases 1 to 6154)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   5  (bases 1 to 6154)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   6  (bases 1 to 6154)
  AUTHORS   Yue,Z., Horton,A., Bravin,M., DeJager,P.L., Selimi,F. and Heintz,N.
  TITLE     A novel protein complex linking the delta 2 glutamate receptor and
            autophagy: implications for neurodegeneration in lurcher mice
  JOURNAL   Neuron 35 (5), 921-933 (2002)
   PUBMED   12372286
REFERENCE   7  (bases 1 to 6154)
  AUTHORS   Ly,C.D., Roche,K.W., Lee,H.K. and Wenthold,R.J.
  TITLE     Identification of rat EMAP, a delta-glutamate receptor binding
            protein
  JOURNAL   Biochem Biophys Res Commun 291 (1), 85-90 (2002)
   PUBMED   11829466
REFERENCE   8  (bases 1 to 6154)
  AUTHORS   Roche,K.W., Ly,C.D., Petralia,R.S., Wang,Y.X., McGee,A.W.,
            Bredt,D.S. and Wenthold,R.J.
  TITLE     Postsynaptic density-93 interacts with the delta2 glutamate
            receptor subunit at parallel fiber synapses
  JOURNAL   J Neurosci 19 (10), 3926-3934 (1999)
   PUBMED   10234023
REFERENCE   9  (bases 1 to 6154)
  AUTHORS   Treadaway,J. and Zuo,J.
  TITLE     Mapping of the mouse glutamate receptor delta1 subunit (Grid1) to
            chromosome 14
  JOURNAL   Genomics 54 (2), 359-360 (1998)
   PUBMED   9828146
REFERENCE   10 (bases 1 to 6154)
  AUTHORS   Yamazaki,M., Araki,K., Shibata,A. and Mishina,M.
  TITLE     Molecular cloning of a cDNA encoding a novel member of the mouse
            glutamate receptor channel family
  JOURNAL   Biochem Biophys Res Commun 183 (2), 886-892 (1992)
   PUBMED   1372507
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL844892.5, DR001156.1,
            AK127168.1, AK293104.1, AB033046.1 and AC022028.7.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_017551.2.
            
            Summary: This gene encodes a subunit of glutamate receptor
            channels. These channels mediate most of the fast excitatory
            synaptic transmission in the central nervous system and play key
            roles in synaptic plasticity.[provided by RefSeq, Jan 2009].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK127168.1, AK293104.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000327946.12/ ENSP00000330148.7
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               AL844892.5         61349-61650         c
            303-530             DR001156.1         216-443
            531-1461            AK127168.1         214-1144
            1462-1575           AK293104.1         1118-1231
            1576-3633           AK127168.1         1259-3316
            3634-5986           AB033046.1         2579-4931
            5987-6151           AB033046.1         4933-5097
            6152-6154           AC022028.7         38309-38311         c
FEATURES             Location/Qualifiers
     source          1..6154
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /map="10q23.1-q23.2"
     gene            1..6154
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="glutamate ionotropic receptor delta type subunit 1"
                     /db_xref="GeneID:2894"
                     /db_xref="HGNC:HGNC:4575"
                     /db_xref="MIM:610659"
     exon            1..482
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     CDS             404..3433
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="glutamate receptor delta-1 subunit; gluR delta-1
                     subunit; glutamate receptor ionotropic, delta-1"
                     /codon_start=1
                     /product="glutamate receptor ionotropic, delta-1
                     precursor"
                     /protein_id="NP_060021.1"
                     /db_xref="CCDS:CCDS31236.1"
                     /db_xref="GeneID:2894"
                     /db_xref="HGNC:HGNC:4575"
                     /db_xref="MIM:610659"
                     /translation="MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLA
                     VSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANAL
                     QSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTEL
                     RWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELN
                     RYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALG
                     RMTVVRQIFPSAKDNQKCTRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAF
                     HRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYV
                     QFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFV
                     MVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGEL
                     ISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVW
                     ACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASATLHSAIWIVYGAFVQQGGESS
                     VNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQVEMSYGTV
                     RDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFL
                     WDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLD
                     VLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAIGLLLACLVAALELWWN
                     SNRCHQETPKEDKEVNLEQVHRRMNSLMDEDIAHKQISPASIELSALEMGGLAPTQTL
                     EPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSSATMPSMQCKHRSPN
                     GGLFRQSPVKTPIPMSFQPVPGGVLPEALDTSHGTSI"
     exon            483..638
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            639..923
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1129
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1183
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1184..1354
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1516
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..1636
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1637..1738
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1739..1936
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            1937..2261
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            2262..2400
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            2401..2596
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..2763
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            2764..3004
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     exon            3005..6154
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3638..3643
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="hexamer: AGTAAA"
     polyA_site      3660
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="major polyA site"
     regulatory      3691..3696
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="hexamer: AATAAA"
     polyA_site      3714
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="major polyA site"
     regulatory      6133..6138
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
                     /note="hexamer: ATTAAA"
     polyA_site      6154
                     /gene="GRID1"
                     /gene_synonym="GluD1; GluD1-b"
ORIGIN      
        1 agttcgctcc tcgccggggc tcagacacac agccagccca gagccgccac gccggcccgg
       61 ccgccgccgc caccgcctca gcctcccccg aagccgctct agccgcggga agcgccgctg
      121 ccacagccgc gggccgcccc cgccgcgccg gcctgggctc aagctgccag caccgccgca
      181 gccgccaccg gagccggagc gggagcccga ccgcgctggg ctgggctggg ctgggctggg
      241 gcgggcgcag ggcgcagggg cgggcgcgcg ggggaagacg cacgggcggg ctcggctctc
      301 ccggggagcg gcccgggact gcaccgggac cagcgcctcc ccgcttcgcg ctgccctcgg
      361 cctcgccccg ggcccgggtg gatgagccgc gcgcccgggg gacatggaag cgctgacgct
      421 gtggcttctc ccctggatat gccagtgcgt gtcggtgcgg gccgactcca tcatccacat
      481 cggtgccatc ttcgaggaga acgcggccaa ggacgacagg gtgttccagt tggcggtatc
      541 cgacctgagc ctcaacgatg acatcctgca gagcgagaag atcacctact ccatcaaggt
      601 catcgaggcc aacaacccat tccaggctgt gcaggaagcc tgtgacctca tgacccaggg
      661 gattttggcc ttggtcacgt ccactggctg tgcatctgcc aatgccctgc agtccctcac
      721 ggatgccatg cacatcccac acctctttgt ccagcgcaac ccgggagggt cgccacgcac
      781 cgcatgccac ctgaacccca gccccgatgg tgaggcctac acactggctt cgagaccacc
      841 cgtccgcctc aatgatgtca tgctcaggct ggtgacggag ctgcgctggc agaagttcgt
      901 catgttctac gacagcgagt atgatatccg tgggcttcaa agctttctgg accaggcctc
      961 gcggctgggc cttgacgtct ctttacaaaa ggtggacaag aacattagcc acgtattcac
     1021 cagcctcttc accacgatga agacagagga gctgaatcgc taccgggaca cgcttcgccg
     1081 cgccatcctg ctgctcagcc cacagggagc ccactccttc atcaacgagg ccgtggagac
     1141 caacctggct tccaaggaca gccactgggt ctttgtgaat gaggaaatca gtgacccgga
     1201 gatcctggat ctggtccata gtgcccttgg aaggatgacc gtggtccggc aaatctttcc
     1261 gtctgcaaag gacaatcaga aatgcacgag gaacaaccac cgcatctcct ccctgctctg
     1321 cgacccccag gaaggctacc tccagatgct gcagatctcc aacctctatc tgtatgacag
     1381 tgttctgatg ctggccaacg cctttcacag gaagctggag gaccggaagt ggcatagcat
     1441 ggcgagcctc aactgcatac ggaaatccac taagccatgg aatggtggga ggtccatgct
     1501 ggataccatc aaaaagggcc acatcactgg cctcactggg gtgatggagt ttcgggagga
     1561 cagttcgaat ccctatgtcc agtttgaaat ccttggcact acctatagtg agacttttgg
     1621 caaagacatg cgcaagttgg cgacatggga ctcagagaag ggcttgaatg gcagcttgca
     1681 agagaggccc atgggcagcc gcctccaagg attgactctt aaagtggtga ctgtcttgga
     1741 agagcctttc gtgatggtgg ctgagaacat cctaggacag cccaagcgct acaaagggtt
     1801 ctccatagat gtcctggatg cactggccaa ggctctgggc tttaaatatg agatttacca
     1861 agcccctgat ggcaggtacg gtcaccagct ccataacacc tcctggaacg ggatgatcgg
     1921 ggagctcatc agcaagagag cagacttggc catctctgcc atcaccatca ccccagagag
     1981 ggagagcgtt gtggacttca gcaagcggta catggactat tcagtgggga ttctaattaa
     2041 gaagcccgag gagaaaatca gcatcttctc cctctttgct ccatttgatt tcgctgtgtg
     2101 ggcctgcatt gcagcagcca tccctgtggt tggtgtgctg atatttgtgt tgaacaggat
     2161 acaggctgtg agggctcaga gtgctgccca gcccaggccg tcagcttctg ccactctgca
     2221 cagcgccatc tggattgtct atggagcctt cgtacagcaa ggtggcgaat cttccgtgaa
     2281 ctccatggcc atgcgcatcg tgatgggcag ctggtggctc ttcacgctca ttgtgtgctc
     2341 ctcctacaca gccaaccttg ctgccttcct cacagtgtcc aggatggaca accccataag
     2401 gactttccag gacctgtcca aacaagtgga aatgtcttat ggcactgtcc gggattctgc
     2461 tgtatatgag tacttccgag ccaagggcac caaccccctg gagcaggaca gcacgtttgc
     2521 tgaactctgg cggaccatca gcaagaacgg aggggctgac aactgcgtgt ccagtccttc
     2581 agaaggcatc aggaaggcaa agaaggggaa ctacgccttc ctgtgggatg tggccgtggt
     2641 ggaatacgca gccctgacgg atgacgactg ctcggtgact gtcatcggca acagcatcag
     2701 cagcaagggt tacgggattg ccctgcagca tggcagcccc tacagggacc tcttctccca
     2761 gaggatcctg gagctgcagg acacagggga cctggatgtg ctgaagcaga agtggtggcc
     2821 gcacatgggc cgctgtgacc tcaccagcca tgccagcgcc caggccgacg gcaaatccct
     2881 caagctgcac agcttcgccg gggtcttctg catcctggcc attggcctgc tcctggcctg
     2941 cctggtggct gccctggagt tgtggtggaa cagcaaccgg tgccaccagg agacccccaa
     3001 ggaggacaaa gaagtgaact tggagcaggt ccaccggcgc atgaacagcc tcatggatga
     3061 agacattgct cacaagcaga tttccccagc gtcgattgag ctctcggccc tggagatggg
     3121 gggcctggct cccacccaga ccttggagcc gacacgggag taccagaaca cccagctctc
     3181 ggtcagcacc tttctgccag agcagagcag ccatggcacc agccggacac tctcatcagg
     3241 gcccagcagc aacctgccgc tgccgctgag cagctcggcg accatgccct ccatgcagtg
     3301 caaacacagg tcacccaacg gggggctgtt ccggcagagc ccggtgaaga cccccatccc
     3361 catgtccttc cagcccgtgc ctggaggcgt ccttccagag gctctggaca cctcccacgg
     3421 gacctccatc tgactgcgcc gcctgccctc ctgcccaccc tcccacccac ccgaccagca
     3481 gagcttttta atacaagaaa acaacaacac aaaccacaca cactcgcaca cacacacata
     3541 cacagagact ctttcatttt tcttgtacat atgtgtaaat aatgacagaa tggagtgggg
     3601 taaaagtgta ttttgaatat tcccaatttt cgaagtcagt aaaaaaacac aaaaactgta
     3661 tgaatgactt tgtaaatttt gttctatatg aataaaaagg caaattactt gtgatcattc
     3721 tgaagtgcca aaggagcccc cccattcctg ggcctttctg agggcaggag gggcgaccag
     3781 ataaggagcc cctctctgct gggggagaag ggaagacgag gaaccccaca tgccactcgc
     3841 tgccttgtcc cacagcttgc tgccccattt ctttgctcct ggcacctcgt cccttttagt
     3901 ccctcagctt gataaagagt gagtttggag cccgcattgg gctggcccac tgggttgctg
     3961 tgctgtaggg tgatcggctg ttctgggtag cctggggctg aggaggtgcc ctggactcag
     4021 ggctatcctg tcctgtcttg gatcttgcgg gacgagttag tcaccgctgt gtgtgttgca
     4081 gtgtgcctct gccccatggg cccgagagaa gctgacaatt acccatagtg aggtaattga
     4141 gggctttgat actgagctgt tctcatatca tactgttggc cttgtttttc attttctttt
     4201 caaaattaga agaatcaaaa agtgatagaa tattggggga aggagggcag actccatcgt
     4261 ttcctcaggg agactgggcg gaggtggggt tggtctggaa gaaggtccat gggggcaggg
     4321 agttgcgagg tggggttagt tgcatggacc aggtgaggtg gtggaacaaa aggccaggta
     4381 gaggaagaat attcccttgg gtttggaccc atggtcccag gtgagagaag gaagtgaggc
     4441 catagatgca gggagtagaa gctttgtggt gtcaggcaaa cggactctgt tagtaagagt
     4501 tgggggaggt gcccaggtgg gtggaccagt actccaggtg atggggcatg ctgagaaata
     4561 gagaaaagag accatgttta tttgggtagg aggaagcctt gccttgcgcc ttaggtgaga
     4621 agcataagtg taactcccat ccaccaggga agttgcttgt agccccaaaa gtaaaggcct
     4681 atctctgggt cataaatcct gcaggcagtc caacaaacag ggctggctcc agcacaaact
     4741 ctcccttcca cctttacgac cctctccaga ccagacctgg agtcctcttc aagcagcaat
     4801 ccaacccaga gcaggggccc tccccactca ggcatctgat aacctctgag atttccaggc
     4861 ctatccctgt gcaggtacag ctgcagggaa gcccagtttt ctaagcctag gaccacctaa
     4921 cagcgccccc tccttcagtt gccctttctg aggcaactaa actacagaat cagggaaaga
     4981 accattagga gtggaactgg gggaatctga gttgtgtcac ttcagttcct ctcctaaaga
     5041 caaaggttag tctgatctcc agacccgtca gaatggaata cacagcccac atctgtcact
     5101 gaaggaggtg gagctcccac agccagcagt aatcagggag ctgagagcct ggttctgtga
     5161 tcatggagaa atacaaagtc ctattgattg cttcttctat agccttgtag agtttctaga
     5221 gagatgtatt tatgagggtg ataactagcc caggattgat ttctttccta aagtccctag
     5281 tgacatgatt gagcagtaaa gaacggccaa atcacacagt cagctaaaag cactgtgggg
     5341 aagagagtgt ttataattat gttatttatt gctggatgct gagaatggtc tgatattcgt
     5401 gctacctagg caatccattg acatttctcc aatcagagca tgtggacctt ggagccaggc
     5461 atgctcagag aagcctaggt gggctaccat gaccccgagg aagagcaggc tttgttttcc
     5521 atcagcacgt tgggggccct gccctgaatg gtcaattttt cacatatata tctctctatt
     5581 tttttaatca aactctggtc tcactgcctt atctcacacc aactctgttt cctcattgcc
     5641 ccctgagatg gcctgtcttc tggggtatag cttggatgtc ttcttggatg gttctgctta
     5701 gaatgagtgt caaggaggaa agagagggag atggaggatg tgtttgtgcg cctgtgtgtg
     5761 tgtgtttgtg tgtgtgtgtg tgtgtgagag agagagagag agagagagag accagcatct
     5821 tcaagagaag tattctgctt atacaaaatc cttaacacct catggtgtta ttcttcacca
     5881 tgtttatata tatatatata tatttttttt tttttttaga attttctacc cttggcatga
     5941 ggggaaatga ttgatattca agcaagttct ctaggaaaaa aaaaaacttc ccaactcaga
     6001 tttctgtgtc agctcagaat gtatcttttt ttcatgcttt gctctttgga tttataactc
     6061 tgtttagact attccataca ttttaggtat attttgtgcc ttcagacact gcaaataata
     6121 atcagcattt ggattaaagt tgtttaataa taaa
//
