LOCUS       XM_047450131            5243 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens glutamate ionotropic receptor AMPA type
            subunit 2 (GRIA2), transcript variant X2, mRNA.
ACCESSION   XM_047450131
VERSION     XM_047450131.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5243
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..5243
                     /gene="GRIA2"
                     /gene_synonym="GluA2; gluR-2; gluR-B; GluR-K2; GLUR2;
                     GLURB; HBGR2; NEDLIB"
                     /note="glutamate ionotropic receptor AMPA type subunit 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 58 ESTs, 646 long SRA reads, 17 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 7 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:2891"
                     /db_xref="HGNC:HGNC:4572"
                     /db_xref="MIM:138247"
     CDS             89..2599
                     /gene="GRIA2"
                     /gene_synonym="GluA2; gluR-2; gluR-B; GluR-K2; GLUR2;
                     GLURB; HBGR2; NEDLIB"
                     /codon_start=1
                     /product="glutamate receptor 2 isoform X1"
                     /protein_id="XP_047306087.1"
                     /db_xref="GeneID:2891"
                     /db_xref="HGNC:HGNC:4572"
                     /db_xref="MIM:138247"
                     /translation="MVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGF
                     YDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFA
                     YLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRV
                     ILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDY
                     DDSLVSKFIERWSTLEEKEYPGAHTTTIKYTSALTYDAVQVMTEAFRNLRKQRIEISR
                     RGNAGDCLANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTN
                     GPRKIGYWSEVDKMVVTLTELPSGNDTSGLENKTVVVTTILESPYVMMKKNHEMLEGN
                     ERYEGYCVDLAAEIAKHCGFKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAI
                     APLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYI
                     GVSVVLFLVSRFSPYEWHTEEFEDGRETQSSESTNEFGIFNSLWFSLGAFMQQGCDIS
                     PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLSKQTEIAYGTL
                     DSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTM
                     NEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKW
                     WYDKGECGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKR
                     MKVAKNAQNINPSSSQNSQNFATYKEGYNVYGIESVKI"
ORIGIN      
        1 agcatctccg cagcagctgc aacagccgca cgaagggggg ctatttccta ggggcgccga
       61 tcaagaatac agtgcatttc gagtagggat ggttcagttt tccacttcgg agttcagact
      121 gacaccccac atcgacaatt tggaggtggc aaacagcttc gcagtcacta atgctttctg
      181 ctcccagttt tcgagaggag tctatgctat ttttggattt tatgacaaga agtctgtaaa
      241 taccatcaca tcattttgcg gaacactcca cgtctccttc atcactccca gcttcccaac
      301 agatggcaca catccatttg tcattcagat gagacccgac ctcaaaggag ctctccttag
      361 cttgattgaa tactatcaat gggacaagtt tgcatacctc tatgacagtg acagaggctt
      421 atcaacactg caagctgtgc tggattctgc tgctgaaaag aaatggcaag tgactgctat
      481 caatgtggga aacattaaca atgacaagaa agatgagatg taccgatcac tttttcaaga
      541 tctggagtta aaaaaggaac ggcgtgtaat tctggactgt gaaagggata aagtaaacga
      601 cattgtagac caggttatta ccattggaaa acatgttaaa gggtaccact acatcattgc
      661 aaatctggga tttactgatg gagacctatt aaaaatccag tttggaggtg caaatgtctc
      721 tggatttcag atagtggact atgatgattc gttggtatct aaatttatag aaagatggtc
      781 aacactggaa gaaaaagaat accctggagc tcacacaaca acaattaagt atacttctgc
      841 tctgacctat gatgccgttc aagtgatgac tgaagccttc cgcaacctaa ggaagcaaag
      901 aattgaaatc tcccgaaggg ggaatgcagg agactgtctg gcaaacccag cagtgccctg
      961 gggacaaggt gtagaaatag aaagggccct caaacaggtt caggttgaag gtctctcagg
     1021 aaatataaag tttgaccaga atggaaaaag aataaactat acaattaaca tcatggagct
     1081 caaaactaat gggccccgga agattggcta ctggagtgaa gtggacaaaa tggttgttac
     1141 ccttactgag ctcccttctg gaaatgacac ctctgggctt gagaataaga ctgttgttgt
     1201 caccacaatt ttggaatctc cgtatgttat gatgaagaaa aatcatgaaa tgcttgaagg
     1261 caatgagcgc tatgagggct actgtgttga cctggctgca gaaatcgcca aacattgtgg
     1321 gttcaagtac aagttgacaa ttgttggtga tggcaagtat ggggccaggg atgcagacac
     1381 gaaaatttgg aatgggatgg ttggagaact tgtatatggg aaagctgata ttgcaattgc
     1441 tccattaact attacccttg tgagagaaga ggtgattgac ttctcaaagc ccttcatgag
     1501 cctcgggata tctatcatga tcaagaagcc tcagaagtcc aaaccaggag tgttttcctt
     1561 tcttgatcct ttagcctatg agatctggat gtgcattgtt tttgcctaca ttggggtcag
     1621 tgtagtttta ttcctggtca gcagatttag cccctacgag tggcacactg aggagtttga
     1681 agatggaaga gaaacacaaa gtagtgaatc aactaatgaa tttgggattt ttaatagtct
     1741 ctggttttcc ttgggtgcct ttatgcagca aggatgcgat atttcgccaa gatccctctc
     1801 tgggcgcatt gttggaggtg tgtggtggtt ctttaccctg atcataatct cctcctacac
     1861 ggctaactta gctgccttcc tgactgtaga gaggatggtg tctcccatcg aaagtgctga
     1921 ggatctttct aagcaaacag aaattgctta tggaacatta gactctggct ccactaaaga
     1981 gtttttcagg agatctaaaa ttgcagtgtt tgataaaatg tggacctaca tgcggagtgc
     2041 ggagccctct gtgtttgtga ggactacggc cgaaggggtg gctagagtgc ggaagtccaa
     2101 agggaaatat gcctacttgt tggagtccac gatgaacgag tacattgagc aaaggaagcc
     2161 ttgcgacacc atgaaagttg gtggaaacct ggattccaaa ggctatggca tcgcaacacc
     2221 taaaggatcc tcattaagaa atgcggttaa cctcgcagta ctaaaactga atgaacaagg
     2281 cctgttggac aaattgaaaa acaaatggtg gtacgacaaa ggagagtgcg gcagcggggg
     2341 aggtgattcc aaggaaaaga ccagtgccct cagtctgagc aacgttgctg gagtattcta
     2401 catccttgtc gggggccttg gtttggcaat gctggtggct ttgattgagt tctgttacaa
     2461 gtcaagggcc gaggcgaaac gaatgaaggt ggcaaagaat gcacagaata ttaacccatc
     2521 ttcctcgcag aattcacaga attttgcaac ttataaggaa ggttacaacg tatatggcat
     2581 cgaaagtgtt aaaatttagg ggatgacctt gaatgatgcc atgaggaaca aggcaaggct
     2641 gtcaattaca ggaagtactg gagaaaatgg acgtgttatg actccagaat ttcccaaagc
     2701 agtgcatgct gtcccttacg tgagtcctgg catgggaatg aatgtcagtg tgactgatct
     2761 ctcgtgattg ataagaacct tttgagtgcc ttacacaatg gttttcttgt gtgtttattg
     2821 tcaaagtggt gagaggcatc cagtatcttg aagacttttc tttcagccaa gaattcttaa
     2881 atatgtggag ttcatcttga attgtaagga atgattaatt aaaacacaac atctttttct
     2941 actcgagtta cagacaaagc gtggtggaca tgcacagcta acatggaagt actataattt
     3001 acctgaagtc tttgtacaga caacaaacct gtttctgcag ccactattgt tagtctcttg
     3061 attcataatg acttaagcac acttgacatc aactgcatca agatgtgaca tgttttataa
     3121 aaaaaggaaa aaaaacattt aaaactaaaa aatattttta ggtattttca caaacaaact
     3181 ggcttttaaa taaatttgct tccatattgg ttgaataaga caaaaacaat taaactgagt
     3241 gggaagtgaa taaaaaaagg ctttaggtat cgattccata tttttcaaag ccaaatatgt
     3301 aaatgctaag gaaagtaaac aaagaggaga ttccaatctt gtaatttaat attgttatta
     3361 aaactttaat gtatcctatt ctttaacatt tggtgttaat ataaaattac ttggcaatgc
     3421 ttgacatttg aaataaacat ttttctattg ttttattgca agtggtccaa ttaattttgc
     3481 ttagctacag tttggtcata aatcaagtga gtttaaagac actaccaagt tgttaggtgc
     3541 ccagagaaaa tttctccctt ttaaaaaggc caggtgattt ttcaaatgta atcttgcccc
     3601 caaagtaata tctgaatatc tttttgacat gtctaaatat atatatatat aaagaaatat
     3661 ttgttaacac aaaagcattt gatctatgta gataaatgct aatagattta aaaagctaat
     3721 attaacaaat accagaatac gtgaagttcc atttttaaag tgtttgagct tacagaagag
     3781 aaacattcat tttaaatgaa gtaaaaaatg ccttgaaagt aattctttag atagttgccc
     3841 attgattaaa ttccaaaaac taaatatgtt tttagcttta aaattataaa agctgtcata
     3901 aactttatat attatgaatt ttaaaatatg tttgagtctc ctgcaatata gtttcatccc
     3961 attgacatca attaaaaata accctaatat attattttta tatttattcc tcaggtggaa
     4021 tggctatttt aatatgccca gtgtggataa aatgtcacat ttctgtaact tttgactaaa
     4081 gagcctatat ttatctagtt aatgaattta aaggatctat ctttcccttc ataaaatacc
     4141 tcttatttcc attaaagccc cccaagttta attaatttag gattttgaat gattattgac
     4201 atccaatagt tatttttaat atttgtattc ttgttatttc tggaagaaag cctttgtgta
     4261 gcacttggta ttttgcaaag tgcttttaaa acattcttac ttaccgtatt tcatagaagg
     4321 gaaggaaaaa tgtaaggttt aacagtaagc acttgcattg aacatggagg catgtggtat
     4381 catgatattc ttcactaaat ttagctgtcc ctaatcacag atcctaaggt aatataatat
     4441 aattttagtg catttctcct catcaggaat gctggaggtg cattttaagt tttaataata
     4501 agtgctagaa tgaccaaatt gcagactaat tgtttccata ttgtacttaa aatgagtttt
     4561 taaaagtgaa aaagaaatga ctatatacaa tcaatgctat ttattgtacc tctgggccta
     4621 ctcttctaaa aattgtagct tatcgatttt tctctgtcaa gcttgaacta atgtaaataa
     4681 ttgaaataat gtaaagttat attttcatgt ttttatagat acaacatgac aagaatacat
     4741 aatgtaagag tatttcaact atggataatg ttgattggat aatgcacatc tcagttacaa
     4801 gcagtactca tagtttaata tccatgtaac ggtgcatcaa tatattgcta tataaatatg
     4861 tctgtgtgca tataagtgaa aagtggtcaa acaagagtga tgacagctgt ctaaaggttt
     4921 ttttattcat tttatataaa aactgttatg gaaagaccaa aatgtttatg aactattctt
     4981 atgtaaattt acaattgtcc tttactgtac ttttttgttt acagtatagt accttatttt
     5041 ctgctgtgtt aagtgggtgt caaactccaa gaagacatac actttctata acttctattg
     5101 aagatattgg aatttccaat ttttcatgtg tactatgtca gaaaatgctt tcgattttat
     5161 ttttaaatct aacatcggat ggcttttccg gagtgttgta aaaacttcaa tcatacataa
     5221 aacatgttct tacaaaaggc aaa
//
