LOCUS       XM_047446464            8552 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens growth regulating estrogen receptor binding
            1 (GREB1), transcript variant X11, mRNA.
ACCESSION   XM_047446464
VERSION     XM_047446464.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8552
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..8552
                     /gene="GREB1"
                     /note="growth regulating estrogen receptor binding 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 13 ESTs, 1600 long SRA reads, 2 Proteins,
                     and 96% coverage of the annotated genomic feature by
                     RNAseq alignments, including 8 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:9687"
                     /db_xref="HGNC:HGNC:24885"
                     /db_xref="MIM:611736"
     CDS             372..6218
                     /gene="GREB1"
                     /codon_start=1
                     /product="protein GREB1 isoform X2"
                     /protein_id="XP_047302420.1"
                     /db_xref="GeneID:9687"
                     /db_xref="HGNC:HGNC:24885"
                     /db_xref="MIM:611736"
                     /translation="MGNSYAGQLKTTRFEEVLHNSIEASLRSNNLVPRPIFSQLYLEA
                     EQQLAALEGGSRVDNEEEEEEGEGGLETNGPPNPFQLHPLPEGCCTTDGFCQAGKDLR
                     LVSISNEPMDVPAGFLLVGVKSPSLPDHLLVCAVDKRFLPDDNGHNALLGFSGNCVGC
                     GKKGFCYFTEFSNHINLKLTTQPKKQKHLKYYLVRNAQGTLTKGPLICWKGSEFRSRQ
                     IPASTCSSSLFPALESTAAFPSEPVPGTNPSILMGAQQAGPASDHPSLNAAMGPAVFN
                     GKDSPKCQQLAKNNLLALPRPSALGILSNSGPPKKRHKGWSPESPSAPDGGCPQGGGN
                     RAKYESAGMSCVPQVGLVGPASVTFPVVASGEPVSVPDNLLKICKAKPVIFKGHGNFP
                     YLCGNLNDVVVSPLLYTCYQNSQSVSRAYEQYGASAIQPISEEMQLLLTVYYLVQLAA
                     DQVPLMEDLEQIFLRSWRESHLTEIRQYQQAPPQPFPPAPSAAAPVTSAQLPWLASLA
                     ASSCNDSVHVIECAYSLAEGLSEMFRLLVEGKLAKTNYVVIICACRSAAIDSCIAVTG
                     KYQARILSESLLTPAEYQKEVNYELVTGKVDSLGAFFSTLCPEGDIDILLDKFHQENQ
                     GHISSSLAASSVTKAASLDVSGTPVCTSYNLEPHSIRPFQLAVAQKLLSHVCSIADSS
                     TQNLDLGSFEKVDFLICIPPSEVTYQQTLLHVWHSGVLLELGLKKEHMTKQRVEQYVL
                     KLDTEAQTKFKAFLQNSFQNPHTLFVLIHDHAHWDLVSTVHNLYSQSDPSVGLVDRLL
                     NCREVKEAPNIVTLHVTSFPYALQTQHTLISPYNEIHWPASCSNGVDLYHENKKYFGL
                     SEFIESTLSGHSLPLLRYDSSFEAMVTALGKRFPRLHSAVIRTFVLVQHYAAALMAVS
                     GLPQMKNYTSVETLEITQNLLNSPKQCPCGHGLMVLLRVPCSPLAVVAYERLAHVRAR
                     LALEEHFEIILGSPSSGVTVGKHFVKQLRMWQKIEDVEWRPQTYLELEGLPCILIFSG
                     MDPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNEVPLEKGARNEALES
                     DAEKLSSTDNEDEELGTEGSTSEKRSPMKRERSRSHDSASSSLSSKASGSALGGESSA
                     QPTALPQGEHARSPQPRGPAEEGRAPGEKQRPRASQGPPSAISRHSPGPTPQPDCSLR
                     TGQRSVQVSVTSSCSQLSSSSGSSSSSVAPAAGTWVLQASQCSLTKACRQPPIVFLPK
                     LVYDMVVSTDSSGLPKAASLLPSPSVMWASSFRPLLSKTMTSTEQSLYYRQWTVPRPS
                     HMDYGNRAEGRVDGFHPRRLLLSGPPQIGKTGAYLQFLSVLSRMLVRLTEVDVYDEEE
                     ININLREESDWHYLQLSDPWPDLELFKKLPFDYIIHDPKYEDASLICSHYQGIKSEDR
                     GMSRKPEDLYVRRQTARMRLSKYAAYNTYHHCEQCHQYMGFHPRYQLYESTLHAFAFS
                     YSMLGEEIQLHFIIPKSKEHHFVFSQPGGQLESMRLPLVTDKSHEYIKSPTFTPTTGR
                     HEHGLFNLYHAMDGASHLHVLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFL
                     IKELSYHNLELERNRQEELGIKPQDIWPFIVISDDSCVMWNVVDVNSAGERSREFSWS
                     ERNVSLKHIMQHIEAAPDIMHYALLGLRKWSSKTRASEVQEPFSRCHVHNFIILNVDL
                     TQNVQYNQNRFLCDDVDFNLRVHSAGLLLCRFNRFSVMKKQIVVGGHRSFHITSKVSD
                     NSAAVVPAQYICAPDSKHTFLAAPAQLLLEKFLQHHSHLFFPLSLKNHDHPVLSVDCY
                     LNLGSQISVCYVSSRPHSLNISCSDLLFSGLLLYLCDSFVGASFLKKFHFLKGATLCV
                     ICQDRSSLRQTVVRLELEDEWQFRLRDEFQTANAREDRPLFFLTGRHI"
ORIGIN      
        1 gctaaatggt taagagatac ataaatactg cagtagagat gggattttac ctcaaagtgc
       61 aaaggtaaat gaaataaagt tttttcaatg gaaggcttgc agctcttgag gacctgccaa
      121 atggaagaag gacagagacc tggagcccta tggaaagttc tgacaccatg tgtggaagga
      181 catggctttt aacacgtgtg gtgactggag tagctgcagc tgaggacagc caccctttct
      241 tcgtctctgc tgagcgaagg ctacacggcc cttcctcctt gcagctgttt caccttctac
      301 cttgcgtgga gccaggcttt tgcaccgaat ctgagatgcc attttaaaca gaagactcca
      361 tcctcttgaa gatgggaaat tcttacgctg gacagctgaa gacgacacgc tttgaagagg
      421 tcttgcacaa ttccatcgag gcatccctgc ggtccaacaa cctggtgccc aggcccatct
      481 tttcccagct gtacctggaa gctgagcagc agcttgccgc tctagaaggt ggtagccgag
      541 tggacaatga ggaagaggaa gaagagggag aaggagggct ggaaacaaat ggccccccaa
      601 accctttcca gctgcaccct ctgcctgaag gatgctgtac cacagacggg ttttgccagg
      661 ccgggaagga cctgcgcctt gtctccattt ccaacgagcc catggatgtc cctgcgggct
      721 ttctcctcgt gggggtcaag tcccccagcc tgccggacca tctcctggtg tgcgccgttg
      781 acaagaggtt cttgccagat gacaatggcc acaatgctct tcttggtttc tctgggaatt
      841 gtgttggctg tggaaagaaa ggcttctgtt acttcacgga attctccaat catataaatc
      901 tgaaactgac cactcaaccc aagaagcaga aacacttgaa gtattacctg gtccgtaatg
      961 cacaagggac tctaaccaaa ggacctttaa tctgttggaa aggctcagag tttagaagcc
     1021 ggcagatccc cgccagtact tgttccagtt ccctcttccc agccctggag agcacggctg
     1081 ccttccccag cgagcccgtt cctgggacga accccagcat cctgatggga gctcagcagg
     1141 caggaccagc ttctgatcac ccctcactaa acgcagcaat gggtccggct gttttcaacg
     1201 gcaaagattc cccgaagtgc caacaactgg caaagaataa cctgttggcc ctgccgcgac
     1261 catcggcttt aggtatcttg tcaaactccg ggccccccaa aaaacgccac aaagggtggt
     1321 ctccagaatc tccatcagct ccagatggtg gctgccccca aggtggtggg aacagagcta
     1381 agtatgagag cgcaggcatg tcctgcgtgc cgcaggttgg cttggtggga ccagcttcag
     1441 tcacctttcc agtggtggcc tctggagaac cagtgtctgt tcctgacaac ttgctgaaaa
     1501 tatgcaaggc caagccagtg atatttaaag gccatgggaa cttcccttac ctctgtggga
     1561 acctgaatga cgtcgtggtc agccccctct tgtacacgtg ctaccagaat tcccagtctg
     1621 tctcacgggc atacgagcag tacggcgcct ctgccatcca gcccatctcc gaggagatgc
     1681 agctcctgct taccgtctac tacctggtcc agctggccgc ggaccaggtg cccttgatgg
     1741 aggacctgga gcagatcttc ctgcgctctt ggcgcgagtc gcacctgacc gagatccggc
     1801 agtaccagca ggcgccgccg cagcccttcc cgcccgcgcc cagcgccgcg gcacccgtga
     1861 cctccgcgca gctgccctgg ctggccagcc tggccgccag ctcctgcaac gacagcgtgc
     1921 acgtcatcga gtgtgcttac tccctggccg agggcctctc cgagatgttc cggctgttgg
     1981 tcgagggcaa gcttgccaag accaactacg tggtcatcat ctgcgcctgc cgcagcgcgg
     2041 ccatcgactc ctgcatcgcc gtcaccggaa aataccaagc ccggattctt tccgagagcc
     2101 ttctcactcc tgcggagtac cagaaggaag tcaattacga gctggttacg gggaaggtag
     2161 actcgctggg ggccttcttt agcaccctct gtccagaggg tgacattgac attttgctgg
     2221 acaaatttca ccaggaaaat caaggccata tttcttcctc actcgctgcc tcttctgtca
     2281 ctaaagcagc atccctggat gtcagtggga caccggtgtg cacaagttac aatctggagc
     2341 cacacagcat ccggcccttc cagctggcag tagcgcagaa gctcctctcc catgtgtgtt
     2401 ccattgcgga ttccagcacc caaaatctgg acctgggatc ctttgagaag gtggactttc
     2461 tcatttgcat tcccccctca gaagtgacct accagcagac tctgctccat gtgtggcatt
     2521 caggggtttt gctggagctt ggtctgaaga aagagcacat gacgaagcag agggtggaac
     2581 agtatgttct gaagctagac acggaggcac agacaaaatt taaggctttt ctgcaaaact
     2641 ccttccagaa cccgcataca ctttttgtcc taatccatga ccatgcgcac tgggatcttg
     2701 tgagcactgt tcataacctc tattctcaaa gtgacccgtc ggtgggattg gtggaccgat
     2761 tgctcaactg cagggaggtg aaggaggccc ccaacattgt gacacttcac gtgacctcct
     2821 tcccgtatgc actgcagaca cagcacaccc tcatcagccc ctacaacgag atccactggc
     2881 ctgcctcctg cagtaatgga gtggacttat atcatgaaaa taagaagtac ttcgggctgt
     2941 cggagtttat tgaatccacc ctttcaggac acagcctccc cttgctcaga tacgatagct
     3001 cctttgaggc catggtcact gcattaggaa aaaggttccc ccgcctgcac agcgcggtga
     3061 tcaggacctt tgttctcgtg cagcactacg cggccgccct gatggccgta agcggcctcc
     3121 cgcagatgaa gaactacacg tcggtggaga cgctggagat cacgcagaac ctcctcaact
     3181 ccccgaagca gtgcccctgc ggccacgggc tcatggtcct gctgcgggtg ccctgttcgc
     3241 ccctggcggt ggtggcctat gagcggctgg cccacgtgcg ggcccggctg gcgctggagg
     3301 agcactttga gatcatcctg ggcagtccca gctcaggcgt caccgtgggg aagcacttcg
     3361 taaagcagct caggatgtgg cagaaaattg aggatgtgga gtggagaccc cagacttact
     3421 tggagctgga gggtctgcct tgcatcctga tcttcagtgg gatggacccg catggggagt
     3481 ccttgccgag gtctttgagg tactgtgacc tgcgattgat aaactcctcc tgcttggtga
     3541 gaacagcctt ggagcaggag ctgggcctgg ctgcctactt tgtgagcaac gaggttccct
     3601 tggagaaggg ggctaggaac gaggccttgg agagtgatgc tgagaagctg agcagcacag
     3661 acaacgagga tgaggagctg gggacagaag gctctacctc ggagaagaga agccccatga
     3721 aaagggagag gtcccgctcc cacgactcag catcctcatc cctctcctcc aaggcttccg
     3781 gttcagcgct cggtggcgag tcctcggctc agcccacagc actcccccag ggagagcatg
     3841 ccaggtcgcc ccagccccgt ggccccgcag aggagggcag agcccctggt gagaaacaga
     3901 ggccccgggc aagtcagggg ccaccctcgg ccatcagcag gcacagtccc gggccgacgc
     3961 cccagcccga ctgtagcctc aggaccggcc agaggagcgt ccaggtgtcg gtcacctcgt
     4021 cgtgctccca gctgtcctcc tcctcgggct catcctcctc atccgtggcg cccgctgccg
     4081 gcacgtgggt cctgcaggcc tcccagtgct ccttgaccaa ggcctgccgc cagccaccca
     4141 ttgtcttctt gcccaagctc gtgtacgaca tggttgtgtc cactgacagc agtggcctgc
     4201 ccaaggccgc ctccctcctg ccctccccct cggtcatgtg ggccagctct ttccgccccc
     4261 tgctcagcaa gaccatgaca tccaccgagc agtccctcta ctaccggcag tggacggtgc
     4321 cccggcccag ccacatggac tacggcaacc gggccgaggg ccgcgtggac ggcttccacc
     4381 cccgcaggct gctgctcagc ggcccccctc agatcgggaa gacaggtgcc tacctgcagt
     4441 tcctcagtgt cctgtccagg atgcttgttc ggctcacaga agtggatgtc tatgacgagg
     4501 aggagatcaa tatcaacctc agagaagaat ctgactggca ttatctccag cttagcgacc
     4561 cctggccaga cctggagctg ttcaagaagt tgccctttga ctacatcatt cacgacccga
     4621 agtatgaaga tgccagcctg atttgttcgc actatcaggg tataaagagt gaagacagag
     4681 ggatgtcccg gaagccggag gacctttatg tgcggcgtca gacggcacgg atgagactgt
     4741 ccaagtacgc agcgtacaac acttaccacc actgtgagca gtgccaccag tacatgggct
     4801 tccacccccg ctaccagctg tatgagtcca ccctgcacgc ctttgccttc tcttactcca
     4861 tgctaggaga ggagatccag ctgcacttca tcatccccaa gtccaaggag caccactttg
     4921 tcttcagcca acctggaggc cagctggaga gcatgcgact acccctcgtg acagacaaga
     4981 gccatgaata tataaaaagt ccgacattca ctccaaccac cggccgtcac gaacatgggc
     5041 tctttaatct gtaccacgca atggacggtg ccagccattt gcacgtgctg gttgtcaagg
     5101 aatacgagat ggcaatttat aagaaatatt ggcccaacca catcatgctg gtgctcccca
     5161 gtatcttcaa cagtgctgga gttggtgctg ctcatttcct catcaaggag ctgtcctacc
     5221 ataacctgga gctcgagcgg aaccggcagg aggagctggg aatcaagccg caggacatct
     5281 ggcctttcat tgtgatctct gatgactcct gcgtgatgtg gaacgtggtg gatgtcaact
     5341 ctgctgggga gagaagcagg gagttctcct ggtcggaaag gaacgtgtct ttgaagcaca
     5401 tcatgcagca catcgaggcg gcccccgaca tcatgcacta cgccctgctg ggcctgcgga
     5461 agtggtccag caagacccgg gccagcgagg tgcaagagcc cttctcccgc tgccacgtgc
     5521 acaacttcat catcctgaac gtggacctga cccagaacgt gcagtacaac cagaaccggt
     5581 tcctgtgtga cgatgtagac ttcaacctgc gggtgcacag cgccggcctc ctgctctgcc
     5641 ggttcaaccg cttcagcgtg atgaagaagc agatcgtggt gggcggccac aggtccttcc
     5701 acatcacatc caaggtgtct gataactctg ccgcggtcgt gccggcccag tacatctgtg
     5761 ccccggacag caagcacacg ttcctcgcag cgcccgccca gctcctgctg gagaagttcc
     5821 tgcagcacca cagccacctc ttcttcccgc tgtccctgaa gaaccatgac cacccagtgc
     5881 tgtctgtcga ctgttacctg aacctgggat ctcagatttc tgtttgctat gtgagctcca
     5941 ggccccactc tttaaacatc agctgctcgg acttgctgtt cagtgggctg ctgctgtacc
     6001 tctgtgactc ttttgtggga gctagctttt tgaaaaagtt tcattttctg aaaggtgcga
     6061 cgttgtgtgt catctgtcag gaccggagct cactgcgcca gacggtcgtc cgcctggagc
     6121 tcgaggacga gtggcagttc cggctgcgcg atgagttcca gaccgccaat gccagggaag
     6181 accggccgct cttttttctg acgggacgac acatctgagg aagacagcgg cgagttttct
     6241 gaagagatga gtgctcagag ccctcatgct gttgaggcta aagggaggcc tggaacggtg
     6301 gggcgtttga ctggaatgga ccccagggac tgtccaggtg cagcccctcc tagtacacat
     6361 gggcccccga ggccgtggtc ctgggagcca ggaagactcc gcagtgggtg agaatgaaaa
     6421 cttgagactc ccaagttctg ggccagccca ttgctctggg ctgttttaaa gcccatttca
     6481 cgaggaacaa agatttactt cctgtcctgc cattcgtgtg cttccatgga caaacctgat
     6541 ttttttctct tagttctaaa gaatcttggg ttattttgta gcggtgccag tatttcagta
     6601 gatgggattt cagccaagta ggttcccctg taacctccta caaagcaata ttccaaagga
     6661 acattttaac tgtaaaggct ggagacaaga aaaaataagt agatcgtttt aataacaatt
     6721 atttaattgc ctataagttt gctgtttcag aggctagccc aaaggcatca aatttaataa
     6781 agttaaacaa attgatttac ttcagagcaa atatgatcct attaaaataa tatagggtaa
     6841 ataccctacc tcttagaaag ggcaaaaatg caaagaagct ttctttaaaa ctaaaagggt
     6901 tttttggggg gggagttggc ggggaggaaa taaggctaac agaggttgac ctaaaattag
     6961 ccttacaaag gagaaaggac cacattgctt acttgaaaca gacaatgaaa acaaccaaag
     7021 tgatatataa aatagttgat gagaactaga cttatgactg tagtttacta gagtttagtt
     7081 ttcagttgct gaagtagctc attttctctt actaatgttt ggttcctcag ggaagaatct
     7141 cacttgacta gagaggaggt gggaacagaa gagagaagga ggcagggaga tgtatttctt
     7201 agggctcacc ccttcacaga ctgacagaat ggttttgttt tgttttgttt tgttttgttt
     7261 tgtttttgag atggactcta gctctgtcac ccaggctgga gtgcagtggt gcgatctcgg
     7321 ctcactgcaa gctccgcctc ccgggttctc accattctcc tgcctcagcc tcccgagtag
     7381 ctgggactac aggcgcccac caccacgccc ggctaatttt ttgtattttt tagtagagac
     7441 ggggtttcac catgttagcc aggatggtct cgatctcctg acctcgtgat ccgcccgcct
     7501 cggcctccca aagtgctggg attacaggcg tgagccaccg tgcctgcccc agaatggttt
     7561 ttaaagccac agttgagagg ccacccattg cccggcgcct ggacagtgat catcttgttc
     7621 atcttgttca gtcctttctt gtgtgattgg aattattcat cccctttgaa agatgagaag
     7681 gttgagatgc aaagagtcta cctttccaag ttctcactgc tggaaagagc tagaagcaca
     7741 gttcaaagtt ctggcttctg gactctgcag tccaggtctc ccttctccca cttgcctacc
     7801 ctcaatgcca cactgttttt gaagtggccc ataacttgaa ggaaaagttt aaagacagtt
     7861 caatttaatc atcagaatgc attctttttt ttttcggaga cggagtttca ctcttgctgc
     7921 ccaggctgga gtgcaatggt gcaatgacct cggctcactg caacctctgc ctcctgggtt
     7981 caagtgattc tccagcctca gcctcccgag tagctgggat tatgggcgcc caccaccatg
     8041 cccagctaat ttttgtattt ttttttttta gtagagatgg ggtttcgcca ggttggccag
     8101 gctggtcttg tgaactcctg gcctcaggtg atctgcccac ctcatcctcc aaaagtgctg
     8161 ggattacagg catgagccac tgcgcctggc ctcagaatgc attcttacac atctatccta
     8221 gacatttata agcactctaa tggataacaa tccaagaata aatgattgta aaagatgatg
     8281 ccgaagagtt gatgtcaatc tttttttcct aagaaaaaaa gtccgcgagt attaaatatt
     8341 tagatcaatg tttataaaat gattactttg tatatctcat tattcctatt ttggaataaa
     8401 aactgacctt ctttaatcat atacttgtct tttgtaaata gcagcttttg tgtcattctc
     8461 cccactttat tagttaattt aaattggaaa aaaccctcaa actaatattc ttgtctgttc
     8521 cagtcttata aataaaactt ataatgcatg ta
//
