LOCUS       XM_047420234            5389 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens growth factor receptor bound protein 10
            (GRB10), transcript variant X8, mRNA.
ACCESSION   XM_047420234
VERSION     XM_047420234.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5389
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..5389
                     /gene="GRB10"
                     /gene_synonym="Grb-10; GRB-IR; IRBP; MEG1; RSS"
                     /note="growth factor receptor bound protein 10; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 31 ESTs, 921 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:2887"
                     /db_xref="HGNC:HGNC:4564"
                     /db_xref="MIM:601523"
     CDS             604..2505
                     /gene="GRB10"
                     /gene_synonym="Grb-10; GRB-IR; IRBP; MEG1; RSS"
                     /codon_start=1
                     /product="growth factor receptor-bound protein 10 isoform
                     X6"
                     /protein_id="XP_047276190.1"
                     /db_xref="GeneID:2887"
                     /db_xref="HGNC:HGNC:4564"
                     /db_xref="MIM:601523"
                     /translation="MQAAGPLFRSKDKVEQTPRSQQDPAGPGLPAQSDRLANHQEDDV
                     DLEALVNDMNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQR
                     VQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAA
                     KQNRKSRAGDSSHHSLVLCHGTCPLSTTAAGETRVGLVTQKQLFHIRDVKVFSEDGTS
                     KVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVESTM
                     ASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNSSSCPEIQG
                     FLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQ
                     YNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQ
                     QRKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRM
                     NILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPK
                     AFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKL
                     KHHCIRVAL"
ORIGIN      
        1 agcgcagtaa atgtaatttg aagaaggcag aaggaaccca tggctttagc cggctgccca
       61 gattcctttt tgcaccatcc gtactaccag cgtcattgtg aaaattggaa gacacttata
      121 taaactttgg cattgtgttt agcacacaaa agaccctgtt aaatgtgagc cactgtttgg
      181 atgagctgtt gattggcaga ccatggctgg gtattagggt accaggtgaa caagatgtca
      241 accctgcctg cagggagctc ccagccctgg agggagacag acagccttcc accgactctg
      301 tgaattgggt accttcatga tacccatttt ataaatgaga aaactgaggt ttttactata
      361 tgctggtcat catgctgagg actttacttg gattttctct cctgccaatg ctacgcggtg
      421 gggaccttca tgttctcccc tttgcagatg agattatcaa agcagaaaaa gaccatctct
      481 cctactgagt aacagaggaa accagggctt gcagatattg gttctgaaaa tattgtgcac
      541 agggcaggct gaggacacag ccacgtgata cccactgtag agagagggag agagagacct
      601 cctatgcaag ctgccggccc tctgttccgt agtaaggaca aggtggagca gacacctcgc
      661 agtcaacaag acccggcagg accaggactc cccgcacagt ctgaccgact tgcgaatcac
      721 caggaggatg atgtggacct ggaagccctg gtgaacgata tgaatgcatc cctggagagc
      781 ctgtactcgg cctgcagcat gcagtcagac acggtgcccc tcctgcagaa tggccagcat
      841 gcccgcagcc agcctcgggc ttcaggccct cctcggtcca tccagccaca ggtgtccccg
      901 aggcagaggg tgcagcgctc ccagcctgtg cacatcctcg ctgtcaggcg ccttcaggag
      961 gaagaccagc agtttagaac ctcatctctg ccggccatcc ccaatccttt tcctgaactc
     1021 tgtggccctg ggagcccccc tgtgctcacg ccgggttctt tacctccgag ccaggccgcc
     1081 gcaaagcaga acaggaagtc tagggccgga gacagcagcc accacagcct cgtcctgtgt
     1141 cacggcactt gtcctctctc cacaacggca gctggtgaga ccagagttgg gcttgtcacc
     1201 cagaagcagc tgttccatat acgggatgtt aaagtcttta gtgaagatgg gacaagcaaa
     1261 gtggtggaga ttctagcaga catgacagcc agagacctgt gccaattgct ggtttacaaa
     1321 agtcactgtg tggatgacaa cagctggaca ctagtggagc accacccgca cctaggatta
     1381 gagaggtgct tggaagacca tgagctggtg gtccaggtgg agagtaccat ggccagtgag
     1441 agtaaatttc tattcaggaa gaattacgca aaatacgagt tctttaaaaa tcccatgaat
     1501 ttcttcccag aacagatggt tacttggtgc cagcagtcaa atggcagtca aacccagctt
     1561 ttgcagaatt ttctgaactc cagtagttgt cctgaaattc aagggttttt gcatgtgaaa
     1621 gagctgggaa agaaatcatg gaaaaagctg tatgtgtgtt tgcggagatc tggcctttat
     1681 tgctccacca agggaacttc aaaggaaccc agacacctgc agctgctggc cgacctggag
     1741 gacagcaaca tcttctccct gatcgctggc aggaagcagt acaacgcccc tacagaccac
     1801 gggctctgca taaagccaaa caaagtcagg aatgaaacta aagagctgag gttgctctgt
     1861 gcagaggacg agcaaaccag gacgtgctgg atgacagcgt tcagactcct caagtatgga
     1921 atgctccttt accagaatta ccgaatccct cagcagagga aggccttgct gtccccgttc
     1981 tcgacgccag tgcgcagtgt ctccgagaac tccctcgtgg caatggattt ttctgggcaa
     2041 acaggacgcg tgatagagaa tccggcagag gcccagagcg cagccctgga ggagggccac
     2101 gcctggagga agcgaagcac acggatgaac atcctaggta gccaaagtcc cctccaccct
     2161 tctaccctaa gtacagtgat tcacaggaca cagcactggt ttcacgggag gatctccagg
     2221 gaggaatccc acaggatcat taaacagcaa gggctcgtgg atgggctttt tctcctccgt
     2281 gacagccaga gtaatccaaa ggcatttgta ctcacactgt gtcatcacca gaaaattaaa
     2341 aatttccaga tcttaccttg cgaggacgac gggcagacgt tcttcagcct agatgacggg
     2401 aacaccaaat tctctgacct gatccagctg gttgactttt accagctgaa caaaggagtc
     2461 ctgccttgca aactcaagca ccactgcatc cgagtggcct tatgaccgca gatgtcctct
     2521 cggctgaaga ctggaggaag tgaacactgg agtgaagaag cggtctgtgc gttggtgaag
     2581 aacacacatc gattctgcac ctggggaccc agagcgagat gggtttgttc ggtgccagcc
     2641 gaccaagatt gactagtttg ttggacttaa acgacgattt gctgctgtga acccagcagg
     2701 gtcgcctccc tctgcatcgg ccaaattggg gagggcatgg aagatccagc ggaaagttga
     2761 aaataaactg gaatgatcat cttggcttgg gccgcttagg aacaagaacc ggagagaagt
     2821 gattggaaat gaactcttgc cctggaataa tcttgacaat taaaactgat atgtttactt
     2881 tttttgtatt gatcactttt ttgcactcct tctttgtttt caatattgta ttcagcctat
     2941 tgtaggaggg ggatgtggcg tttcaactca tataatacag aaagagtttt gaatgggcag
     3001 atttcaaact gaatatgggt ccccaaatgt tcccagaggg tcctccacac cctctgccga
     3061 ctaccacggt gtggattcag ctcccaaatg acaaacccag cccttcccag tatacttgaa
     3121 aagctttctt gttaaaataa aaggtgtcac tgtggtaggc atttggcata ttttgtggac
     3181 tcagtcaagc aaccacagtc tgttaatcat ttctctatgc tcagatgtca gatcctcttg
     3241 ttattagtgt gtcttgttct gcacagtgca ggagacttta ttcctttgga aaattcactg
     3301 ttccacaaac agcaggctga atggcctcgc ctctagattg acgtgggcca gcctccttga
     3361 gacacacctg gcacccgtca tcggccagcg gtggatgctg cataatccac ctgggtactt
     3421 cagccttgcg tttccacagc cttcagcctg ttctagaacg atcactgcct tacccctgct
     3481 gctgcagtgg tgtgagtcgt ttcacggctg atgtccctcg ggggattaaa ggatctaaag
     3541 agaaaatggc acctggttgt cttcgtgctg tgtctcatgg gtttccatag tgataaagac
     3601 aaggaaacgc tgcaggggcc acaggcacag gctgatattt aaagatcttt gcttgcagcc
     3661 ctccgtcctg ctgaaaaccc ccataagcca gtgaacacag agcagctaga ggctcctcct
     3721 ctgctggctt agggtcagaa gtacctcaca gtggttgtgg acatggaaga gttttgtcaa
     3781 cacaacactt tgtccccgct ccgggagatg agtcagatgg tggcttgagt tgtcacttgg
     3841 tcccctccgc ccctcgggtg gccccctttg ccacgtcccc ttagcttagt gatcaggtgt
     3901 gagagtggcc atttccttac ctttgatccc tgtaaagcag aaaggactcc tttgacaggc
     3961 gacaaactac tgtggtgagc agaatgattt cctttttcaa gacaacacct gcctggcttc
     4021 tattaatgtg tgctggccat gatattgccc caaatccgcc ccactgaagt gttccctaag
     4081 gaacagcatt tctctgctcc tcagtcaacc cccgtagcct agagcagtgt cacaagcttc
     4141 agtaaggcca gtcagctgga agtcagtcta ccgtatagta acactgtatg tcagtctaca
     4201 gaccacactc tagttgtttt ccatgaaagg tatacaaatg aagaattttc tagcaaaaca
     4261 tgtttttaac catcagtgct caattgcatt ttcttccttt cgcagccagt cagtctttca
     4321 aactattgac agtaagataa ttctcacgtt cacacctggt ggcaggcttc actgtaggga
     4381 cggacattgc agttacacca cgattccttc ctcttcactg gctcgaggta aacccttttc
     4441 aaggaaaaac aactctagga tttctttttt ctgtgtacgt agaccagtcc catcagtgta
     4501 taatctctct ctcacacgcc tctctccaat agacagcttg tatttgcagt atttcatatt
     4561 tataaatatg cgtttattta aaaggagaac aaaagcttga ctctgattca cagttttgta
     4621 tgtagctggt ttgacgtagt cttttgtatt ttccctgccg aagtgaattg ttggagaatg
     4681 taaaccgcct ccacgtggcg gcagacttcc taaggcccca gctcgctggc ctcgcgctgg
     4741 gcggctggga attccacctg agaacaagtc ccgcaaaccg gggacggaag gacatttgac
     4801 ttttattttt gtatttaatt gacatgaatg taaaggggac agctcagggt tgttttggag
     4861 cctgttgact ttgtatctct gcctgtgatt ttcttttcta aatgaaactc catgtagcaa
     4921 ccaggacgaa gttgagaagg aaaacgccaa atgctttggt tattagagtt taataggtaa
     4981 gctctgttac actaggtgtt agagttccag aatgttcttt tgtttgctaa accttgaaga
     5041 aacatgtgcc tcagcctaga tgttttgtct tctcttttct gcacttaata cctgacagta
     5101 tgaccgatct ctgcgccttt ctgggggcgg gcaagctggc ggtagatttg tgatgtcaca
     5161 gtgcaaactg cagtgactgt aaattggcct ggcgtgtata aacgttttca gggaatgcag
     5221 aaggtattaa tgaagagaca aaacctttat tccatgtgct ttgcttcatt ctgtacatag
     5281 ctctttggct cgtgaaccta attgtaaact ttcaggtatt tttgtacaaa taagggactg
     5341 atgttctgtt tcttgtaatt agaaataaac attaatacag tgttcttca
//
