LOCUS       NM_001387025            8330 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens GRAM domain containing 1B (GRAMD1B), transcript
            variant 11, mRNA.
ACCESSION   NM_001387025
VERSION     NM_001387025.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 8330)
  AUTHORS   Bandara,S., Ramkumar,S., Imanishi,S., Thomas,L.D., Sawant,O.B.,
            Imanishi,Y. and von Lintig,J.
  TITLE     Aster proteins mediate carotenoid transport in mammalian cells
  JOURNAL   Proc Natl Acad Sci U S A 119 (15), e2200068119 (2022)
   PUBMED   35394870
  REMARK    GeneRIF: Aster proteins mediate carotenoid transport in mammalian
            cells.
REFERENCE   2  (bases 1 to 8330)
  AUTHORS   Ercan,B., Naito,T., Koh,D.H.Z., Dharmawan,D. and Saheki,Y.
  TITLE     Molecular basis of accessible plasma membrane cholesterol
            recognition by the GRAM domain of GRAMD1b
  JOURNAL   EMBO J 40 (6), e106524 (2021)
   PUBMED   33604931
  REMARK    GeneRIF: Molecular basis of accessible plasma membrane cholesterol
            recognition by the GRAM domain of GRAMD1b.
REFERENCE   3  (bases 1 to 8330)
  AUTHORS   Andersen,J.P., Zhang,J., Sun,H., Liu,X., Liu,J., Nie,J. and Shi,Y.
  TITLE     Aster-B coordinates with Arf1 to regulate mitochondrial cholesterol
            transport
  JOURNAL   Mol Metab 42, 101055 (2020)
   PUBMED   32738348
  REMARK    GeneRIF: Aster-B coordinates with Arf1 to regulate mitochondrial
            cholesterol transport.
REFERENCE   4  (bases 1 to 8330)
  AUTHORS   Dai,X., Guo,X., Liu,J., Cheng,A., Peng,X., Zha,L. and Wang,Z.
  TITLE     Circular RNA circGRAMD1B inhibits gastric cancer progression by
            sponging miR-130a-3p and regulating PTEN and p21 expression
  JOURNAL   Aging (Albany NY) 11 (21), 9689-9708 (2019)
   PUBMED   31719211
  REMARK    GeneRIF: Circular RNA circGRAMD1B inhibits gastric cancer
            progression by sponging miR-130a-3p and regulating PTEN and p21
            expression.
REFERENCE   5  (bases 1 to 8330)
  AUTHORS   Sandhu,J., Li,S., Fairall,L., Pfisterer,S.G., Gurnett,J.E.,
            Xiao,X., Weston,T.A., Vashi,D., Ferrari,A., Orozco,J.L.,
            Hartman,C.L., Strugatsky,D., Lee,S.D., He,C., Hong,C., Jiang,H.,
            Bentolila,L.A., Gatta,A.T., Levine,T.P., Ferng,A., Lee,R.,
            Ford,D.A., Young,S.G., Ikonen,E., Schwabe,J.W.R. and Tontonoz,P.
  TITLE     Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER
            Cholesterol Transport in Mammalian Cells
  JOURNAL   Cell 175 (2), 514-529 (2018)
   PUBMED   30220461
REFERENCE   6  (bases 1 to 8330)
  AUTHORS   Khanna,P., Lee,J.S., Sereemaspun,A., Lee,H. and Baeg,G.H.
  TITLE     GRAMD1B regulates cell migration in breast cancer cells through
            JAK/STAT and Akt signaling
  JOURNAL   Sci Rep 8 (1), 9511 (2018)
   PUBMED   29934528
  REMARK    GeneRIF: GRAMD1B regulates cell migration in breast cancer cells
            through JAK/STAT and Akt signaling
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 8330)
  AUTHORS   Wistow,G., Bernstein,S.L., Wyatt,M.K., Ray,S., Behal,A.,
            Touchman,J.W., Bouffard,G., Smith,D. and Peterson,K.
  TITLE     Expressed sequence tag analysis of human retina for the NEIBank
            Project: retbindin, an abundant, novel retinal cDNA and alternative
            splicing of other retina-preferred gene transcripts
  JOURNAL   Mol Vis 8, 196-204 (2002)
   PUBMED   12107411
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP000783.4, AP000841.4 and AP002765.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038191.478807.1,
                                           SRR14038195.682583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000635736.2/ ENSP00000490062.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-898               AP000783.4         59702-60599
            899-976             AP000841.4         2982-3059
            977-1187            AP002765.3         30726-30936
            1188-1208           AP002765.3         37671-37691
            1209-1293           AP002765.3         47441-47525
            1294-1397           AP002765.3         48094-48197
            1398-1493           AP002765.3         49301-49396
            1494-1574           AP002765.3         53827-53907
            1575-1690           AP002765.3         56785-56900
            1691-1847           AP002765.3         58681-58837
            1848-2037           AP002765.3         59968-60157
            2038-2181           AP002765.3         62018-62161
            2182-2300           AP002765.3         63154-63272
            2301-2443           AP002765.3         63555-63697
            2444-2547           AP002765.3         66120-66223
            2548-2751           AP002765.3         66814-67017
            2752-2842           AP002765.3         68104-68194
            2843-2950           AP002765.3         72052-72159
            2951-3068           AP002765.3         72466-72583
            3069-8330           AP002765.3         75865-81126
FEATURES             Location/Qualifiers
     source          1..8330
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q24.1"
     gene            1..8330
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /note="GRAM domain containing 1B"
                     /db_xref="GeneID:57476"
                     /db_xref="HGNC:HGNC:29214"
                     /db_xref="MIM:620179"
     exon            1..898
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     CDS             525..3158
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /note="isoform 11 is encoded by transcript variant 11;
                     GRAM domain-containing protein 1B; long intergenic
                     non-protein coding RNA 1059; protein Aster-B"
                     /codon_start=1
                     /product="protein Aster-B isoform 11"
                     /protein_id="NP_001373954.1"
                     /db_xref="CCDS:CCDS91613.1"
                     /db_xref="GeneID:57476"
                     /db_xref="HGNC:HGNC:29214"
                     /db_xref="MIM:620179"
                     /translation="MPAANMMENRPLPALQVPEPQGAPEGSPVWSSSSTPTLRRRRFK
                     MRRMKNVQEQSLEAGLARDLPAVLAPGKEFLQLPSIEITPSSDEDTPWSNCSTPSASP
                     RRKRFLLRKWLRVRERKECSESSSQQSSQQSSHDDDSSRFLSPRAREESTASNSNRST
                     PACSPILRKRSRSPTPQNQDGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGK
                     NSKKSQSWYNVLSPTYKQRNEDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSE
                     NWICFYSNIFRWETLLTVRLKDICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDR
                     TYMMMFRLWQNALLEKPLCPKELWHFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYCE
                     EIPVEENEVNDSSSKSSIETKPDASPQLPKKSITNSTLTSTGSSEAPVSFDGLPLEEE
                     ALEGDGSLEKELAIDNIMGEKIEMIAPVNSPSLDFNDNEDIPTELSDSSDTHDEGEVQ
                     AFYEDLSGRQYVNEVFNFSVDKLYDLLFTNSPFQRDFMEQRRFSDIIFHPWKKEENGN
                     QSRVILYTITLTNPLAPKTATVRETQTMYKASQESECYVIDAEVLTHDVPYHDYFYTI
                     NRYTLTRVARNKSRLRVSTELRYRKQPWGLVKTFIEKNFWSGLEDYFRHLESELAKTE
                     STYLAEMHRQSPKEKASKTTTVRRRKRPHAHLRVPHLEEVMSPVTTPTDEDVGHRIKH
                     VAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVLVLLVILNMMLFYKLWMLEYTTQTL
                     TAWQGLRLQERLPQSQTEWAQLLESQQKYHDTELQKWREIIKSSVMLLDQMKDSLINL
                     QNGIRSRDYTSESEEKRNRYH"
     exon            899..976
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1187
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1208
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1293
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1397
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1398..1493
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1574
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1690
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1847
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..2037
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2038..2181
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2182..2300
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2443
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2444..2547
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2548..2751
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2752..2842
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2843..2950
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..3068
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     exon            3069..8330
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8308..8313
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /note="hexamer: AAGAAA"
     polyA_site      8330
                     /gene="GRAMD1B"
                     /gene_synonym="LINC01059"
                     /note="major polyA site"
ORIGIN      
        1 ctctctctct ctgtctctct ctccctttcc ctcctaccac tgcctcttcc tcccgctctc
       61 tacctccctg cagcgccaag ccggctcccc aacctggtct gctgaacgca aaccgctgag
      121 agtttgctgc accgccccct ggggcccctg gctgccgagt cccgctaagg caaagacgcc
      181 agcaagcgag gaagcgcagc ggaagaaaaa caagcgggcg cgcgagggga gccccaggag
      241 ggctgccgag tggctggcag gcggctcccg cccctcccgg gtggcctcgc cggcggctga
      301 cggcccggag gacgcgcgct ccgaaaagtt agactccggg cggcggcgcg ctacgccgcg
      361 tcccctcgcg tcccttcctc gctgcgctcc gggaaaggaa cttgttcctt cggccccagg
      421 attggggagt gtgccgcggg gccgagggtg gggaacagcc agagggagac gcgaaccagg
      481 ccgctggcgg agggctcagg gggagcgcag aggcgacggc ccccatgccg gcggccaaca
      541 tgatggagaa ccggccgctg cccgccctgc aggtgcccga gccgcagggt gcgcccgagg
      601 gcagcccggt ctggtccagt tcgtcgaccc ccacgcttcg ccgccggcgc ttcaagatgc
      661 gccgcatgaa gaacgtacag gagcagagcc tggaggccgg gctggcccgg gacctgcccg
      721 ccgtcttggc ccccggcaag gagttcctgc agctgccgtc catcgagatc acgccctcca
      781 gcgacgagga caccccgtgg tccaactgct ccacacccag cgcgtccccg cgccgaaaac
      841 gcttcctcct ccgcaagtgg ctgagggtga gggagcggaa ggagtgcagt gaaagcagca
      901 gccaacagag cagtcagcag agcagccacg atgatgattc tagcaggttc ctgagtcctc
      961 gagcgcggga agaaagcact gccagtaact ccaaccgcag cacgccggcc tgctcgccca
     1021 tcctccggaa gcggtctcgc tcgccaaccc cgcagaacca ggacggagac accatggtgg
     1081 agaagggctc agatcactcc tcggacaagt ccccgtccac accggagcag ggcgtgcagc
     1141 gcagctgctc ctcccagtcc ggccggagcg gcggcaagaa ttccaagaaa agccagagtt
     1201 ggtataatgt gttaagcccc acctacaagc agagaaatga agacttcaga aagctcttta
     1261 agcagcttcc agacacggag cgcctcattg ttgattactc atgtgcactc caaagagaca
     1321 ttctccttca gggccgactc tacctctctg aaaattggat ctgcttctac agcaacatct
     1381 tccgctggga aactctgctg acagtccgtt tgaaagacat ctgttccatg actaaagaaa
     1441 aaacagctcg cctcattccc aatgccatcc aagtttgcac tgattcagaa aagcacttct
     1501 tcacttcgtt tggggcccgg gataggacat atatgatgat gttccggctc tggcagaatg
     1561 ctctccttga aaagcctctg tgtcccaagg agctctggca ctttgttcac cagtgctatg
     1621 ggaacgaatt gggcctgacc agtgatgacg aggactacgt gccccctgac gacgacttca
     1681 acacaatggg atactgtgaa gagatccctg tggaagagaa tgaagtgaat gacagctcat
     1741 ccaagagcag catagagacc aagccagatg ccagtccaca gctgcccaag aaatccatca
     1801 ccaacagcac actaacatcc acagggagca gtgaggcccc cgtctcgttt gatgggctgc
     1861 ccctggagga agaggcgctg gagggagacg ggtccctgga aaaggagctc gccattgaca
     1921 acatcatggg ggagaagatt gagatgatcg ctcctgtgaa ctccccttca ctggacttca
     1981 atgacaatga ggacatcccc actgagctca gtgactcttc cgacacacac gatgaaggag
     2041 aggtccaggc cttctatgag gacctgagtg gccggcagta cgtgaatgaa gtcttcaact
     2101 tcagcgtgga caagctctat gacctcctct tcaccaactc gcccttccag cgggatttca
     2161 tggagcagcg gcgcttctct gatatcatct tccatccatg gaaaaaggag gagaatggaa
     2221 accagagccg agtgattctt tacaccatca cccttaccaa ccctctggct cccaaaactg
     2281 ccactgtcag ggagacacag accatgtaca aggcgagcca ggagagtgaa tgttacgtga
     2341 tagatgccga agtcctcacc cacgacgtgc cctaccatga ctacttctac acaatcaatc
     2401 gctacacgct cacccgtgtg gctcggaaca agagccgact cagggtctcc acagagctgc
     2461 gctatcgaaa acagccctgg gggttagtga aaacgttcat cgagaagaac ttctggagtg
     2521 ggctggagga ctacttccgc catttagaga gcgagctggc caaaacggag agcacttatt
     2581 tggctgagat gcacagacaa tctcccaaag agaaggccag caagactaca acggtgcgga
     2641 ggaggaagcg tccccatgcc cacctgcgag tccctcacct ggaagaggtg atgagcccgg
     2701 tcaccacgcc cacagatgag gatgtgggcc acaggatcaa acatgtggca ggttccacac
     2761 agacgcggca tatcccggag gacaccccca acggtttcca cctgcagagc gtgtccaagc
     2821 tgctgctggt tatcagctgt gttctggtgc tgctggtcat ccttaacatg atgctcttct
     2881 acaaactctg gatgttggaa tacaccacgc agaccctcac tgcctggcag ggtctaaggc
     2941 tccaagaaag gttaccccag tctcagacag aatgggccca gctcttagag tcccaacaaa
     3001 agtaccacga tactgagctc caaaaatgga gggaaatcat caaatcctca gtgatgctcc
     3061 ttgaccagat gaaggactcg ctcatcaacc ttcagaacgg catcaggtcc cgcgactaca
     3121 cgtcggaaag tgaagaaaag aggaatcgct atcattgaca aggcaggaac agggtggctg
     3181 caagaggcct gtgcaataca tgtacataga ccatataaat atatatatat aaatatatat
     3241 atatacagaa tataaatata tatattatat acagatttta aaaaagagat aatgcctatg
     3301 taccagggag aaggagcggg ccctcccgcg ccctgtgctg gccggagcag cgttttctta
     3361 tggtggagca gctgaggagg gcaggaaccg cctctcagca ccgacctccc ctgatctccc
     3421 tcctcccacc ctctgttccc caccccttcc cttgctggcc attcttggct tttagaaggg
     3481 aaatgttgag ccaaagttat gcctgcgaag accctaaggt ctcaaaaaga agtcttaaga
     3541 cggcattgct taaggtgctt cattccctaa tccccttttg atttgtttcc aaaataaaag
     3601 agaatctttt cttccctacc ccaggcttcc ccaggcattc tcttgggaac acagaagcat
     3661 caagggagcc cagtctaaac tcctagggtt ggccgcccac ttgatccaga ccgtactgag
     3721 tgtcagatgg agaggatgct tggaaagcta ggaaggctgc attgtgtggt ggcaggctcc
     3781 cgagactcgt gttctgaagg atactctcct ccatcacccc tgcaccttcc tccgacctgt
     3841 gtagggtgtg gacccagtaa gggctgggaa tttcttactt tcccacccgc tttctctctg
     3901 gtcttctccc aggctggatc tgggcgaagt gtcacttttt agtgcctaaa gtcctattgt
     3961 ttctctgtgc cctaagagca cattgtttat tagccagggt ggagcgtttt cgaccttatt
     4021 aaacctcttt tagtgcttct aagcaagtca ggtctgtggc tctgaggcct tcacttagag
     4081 ctgtcagtgt gatttccagg atgagtcagg gtgtgctggg ccctccagga tttgagagag
     4141 ggagagaagg cccttgccac gtccggggtg cagggtctac ccacagaaca ctgtgagtgg
     4201 tgagcaccaa gatgggttgc cagcctcatt tgctctttga acgaaccaac attagccagt
     4261 ggagacgact gtctgagaca gtttgcacat agaaaaagca tctgagccac tggagggaag
     4321 gatttggcaa aggtgcatgt gtttgggcag gaaaaggcca agtgaaatct atgccctacg
     4381 ggagccattc ccaatcctga gtttctcaga cttggcaatg ggggttctgg cgggggttgg
     4441 agtacaaatc ctgctctggt ctctggcccc acagaggtgt aagatcatta agaagtagaa
     4501 ggcactagct tcaaagagtg agacattcag ggccttttca gcattggccc actagcacca
     4561 tgcatttatc tgaattcacg gggccctctg ggcacattca tcatccctca tacactaact
     4621 actgtttctt catgtaatga ccaaaagagt cccaccagct ccaggcagag cttgtggaga
     4681 ttcatgaaag agtcatagcc agtttggcat gcagaggtct tcagtcttgc ttattcttct
     4741 cctgggcttc ttgacacagg ggcagaagaa accccagatg tcccagatgt cccagaacat
     4801 cagcccaaaa gacagaagat tttatcactc atctacccca aagataaagt tgtatttttt
     4861 tcttagaatg gcctttaatt ccctgtggca attacagttt ttgacttttc catgtgagaa
     4921 taaggccttg gtatttccct aagggcagga tcagaaaaca ggaaggtcca tgcccaggtg
     4981 atcctccaag ggaggagggt gaggaggctc cagggcatga gctagagtgg atattcctcc
     5041 cctagaagag gagatgggag gaaatgcagt ttcatgtaat ccctgtgaag agtgcctatg
     5101 cccacagccc agtgggtcct tgttcagttc ttgtccaggc ctttgggtga gggacactgg
     5161 tagggatcaa ggctcatggg ctctgagcca aagaaggagg catggtgcag actgctggaa
     5221 atctccccct tggcacagcc agaagccaaa actattccca gaaagttttg aatgcaaaac
     5281 ttgtagattc ctgaatttat tccatacata attatttcct taagttattt aattattaaa
     5341 ggtgccacgg tgggaccttt gggatgactt aaaaagggtt ctttgttggg agtcaagtga
     5401 cagagcagac ctggccgcag ggagttgttc tgcttctgct ttacctctca ggaccattcc
     5461 caggaggaaa aggtggcaga gagggcagta ctgagtatgt cagaagagcc ctcctggttt
     5521 tttagcgatt tgaacccact agacaatgtg tgcacatagg gaatgtcctt taagaatcat
     5581 ggatctcttg taggctctct gtgttccaat aattttttga ctatcatacc aggaaaaaac
     5641 caacaactct attcattccc aaacaaaatc tcttccccct tagtcaatag cttgcgaaag
     5701 acatcttaac tcacccttgc agataagtct tggagtgaaa caaataaata gcattgtatt
     5761 cctggccatt tgcctggcta gttgctgtct acaagggagc atcaaaacat cactacttct
     5821 tatgtaactt cttccagcca gtgcttttat tgttcgtttt agtttactgg ggacacacag
     5881 gagtctttct gtaatgactt atgtggtaaa atgtttgaga gtttgcactc aattttaaag
     5941 aatttgcagt ttctaacaag gtgaagaaca gctataggat ctaaagttcc attacagctt
     6001 actgtgaaag aattgacaag actggcctca gacaagctaa tcatggtgcg actctctccc
     6061 ttcctcatcc acctctttgg ggacaagagg attacatctc aggccagcaa gatcagctgc
     6121 ttgaagctct gtgtaagagc actgcactga cggtttggag acctgagcct gggtcctgac
     6181 ttttccattg actaagctct gtggccttgg gcaagtcact ccccctctct gagcttcagt
     6241 atcctcctgt cacaggaggg agttgggcta gatcatcttt aaggtaggtt ctagctttga
     6301 catcatcttg ggggttaggc cagaggctgg gaagactggg tggactttct caattgctct
     6361 gccaggaggg aacaagccca gaggctgaag cttcccagta tttagaggtg tggtagggca
     6421 gtgtctgcat tcccaggaga cccagggtga ttaaaattta ttctttaggt ggctaggagg
     6481 gctggggagg cccagtggaa gagagagaga gagagagaga gagagagaga gagagagaga
     6541 gagatcgagc ttgatgtatt gctcagtatt cacttagaag ggtttctttc tctttggcct
     6601 agtttgtgaa gggatcttcc tttggacttt ctctaagttg ggagaagaac attcttttca
     6661 atggagctca tcttctatct ctagggtctg ttcagccttt catctatcca tccttcctct
     6721 ttattggtag aagaaacagt ggagagtagc cacttctggt tctagcactt ctcttttgtt
     6781 aagatagggt ttggatttag tatgaagctt tggctaaaac ccttgggttt gccttagaac
     6841 actgacacta agaacctgga atgacatggg gaggacaaag agagctcaag aggaatgctt
     6901 tgtgagaagt ggattctctc cgtgtccctg ccccccaccc aaacttgaac tatacctatt
     6961 acatttccag gcagtatccc taagatgaga tcctggagaa aggactaggg gaagtatctt
     7021 tctggatgct tgtggtccca gaagggtact ttctgtgtca taccatgcca cttctttaag
     7081 ctcttcaggg cagccaaagc cagccctttt ctcctactgc ccccaggaga aatagcactc
     7141 ttctcccttc ccccagatgg cagggctctg gcctccctac acctcatacc ctgcctgcct
     7201 cctccaggag gaatctccgg ggccccttcc tgactctccc caccttcgcc acttgtctct
     7261 aggctatggg acaatcatcc cattcaccac ttgacatcct tgacatcctt gactttcatt
     7321 cccccaacct ccagcaggtt ggccccaatc ctcttcacct ctgtgttttc ttctagaaga
     7381 tgcattttgg gtctgagagg agcattttcc tggaaggcca tcttttaagg cccctgcttg
     7441 ctgtcatagt gcagagcaga aacttgcaca ctatttagag agctcccttc ccacctctct
     7501 gcccagcctt gttacctcac ttctgctctg gccatggctg tgaagggccc agccagctcc
     7561 ctgttttgat gttctgtgca acagctccgg ggtcttgtga ctggagatcc tcaacaggcc
     7621 ctggagccag gactggagtc ttggcagctg atgagcagca ccttgccggc caggaggagc
     7681 tgatgctgac gatctcccca acatctgaag gcttaaagaa cattgtcgtt cttcagccct
     7741 ccttgcttct ctcaatacaa taagacattg cagaagcaaa agggtggcct ctgctccagg
     7801 caaggcagct ggctctgtct ggggcatcgg cctggggctt gggtgccacg tgctgagatt
     7861 gcatagtcaa aacagccatt tttgccaaca atagcttgtg gctccccaca ttttcctacc
     7921 ctgcactcaa gggccagacc actctctgca tggaccagac catcttccca aacccatggt
     7981 gctttttccc caactcaacc tagactccaa ggtggggagg gatgggtcag aggccatagt
     8041 ggcccctgga taatcctgac gtggggtgga gtggggtgag gcagagggag cagccccaac
     8101 acctgcactg ggccatctat gggaaagaac acgggtcgag tgcagtcgag ttgtctggcc
     8161 atctgtattt ggatctataa ctgtactttg cctggcgctg tgcgcaaggt cagaaaactt
     8221 actgctagta cctagaaaca cacaaggctg cccagccaaa tcttaatgta aagtagctag
     8281 agccatggaa gtacagtatg aattaaaaag aaaaaagtat tgaactacaa
//
