LOCUS       NM_198281              14037 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens GPRIN family member 3 (GPRIN3), mRNA.
ACCESSION   NM_198281 XM_291108
VERSION     NM_198281.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14037)
  AUTHORS   Zhou,W., Ding,X., Jin,P. and Li,P.
  TITLE     miR-6838-5p Affects Cell Growth, Migration, and Invasion by
            Targeting GPRIN3 via the Wnt/beta-Catenin Signaling Pathway in
            Gastric Cancer
  JOURNAL   Pathobiology 87 (6), 327-337 (2020)
   PUBMED   33254176
  REMARK    GeneRIF: miR-6838-5p Affects Cell Growth, Migration, and Invasion
            by Targeting GPRIN3 via the Wnt/beta-Catenin Signaling Pathway in
            Gastric Cancer.
REFERENCE   2  (bases 1 to 14037)
  AUTHORS   Tarabeux,J., Kebir,O., Gauthier,J., Hamdan,F.F., Xiong,L.,
            Piton,A., Spiegelman,D., Henrion,E., Millet,B., Fathalli,F.,
            Joober,R., Rapoport,J.L., DeLisi,L.E., Fombonne,E., Mottron,L.,
            Forget-Dubois,N., Boivin,M., Michaud,J.L., Drapeau,P.,
            Lafreniere,R.G., Rouleau,G.A. and Krebs,M.O.
  CONSRTM   S2D team
  TITLE     Rare mutations in N-methyl-D-aspartate glutamate receptors in
            autism spectrum disorders and schizophrenia
  JOURNAL   Transl Psychiatry 1 (11), e55 (2011)
   PUBMED   22833210
  REMARK    GeneRIF: Functional compensation could occur to counteract the loss
            of one allele in GRIN2C and GRIN3 family genes.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 14037)
  AUTHORS   Iida,N. and Kozasa,T.
  TITLE     Identification and biochemical analysis of GRIN1 and GRIN2
  JOURNAL   Methods Enzymol 390, 475-483 (2004)
   PUBMED   15488195
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093862.3 and AC105388.3.
            
            On Nov 23, 2018 this sequence version replaced NM_198281.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK124616.1, SRR1660807.45637.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000609438.2/ ENSP00000476603.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               AC093862.3         20576-20761         c
            187-6142            AC105388.3         75901-81856         c
            6143-14037          AC105388.3         68006-75900         c
FEATURES             Location/Qualifiers
     source          1..14037
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q22.1"
     gene            1..14037
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="GPRIN family member 3"
                     /db_xref="GeneID:285513"
                     /db_xref="HGNC:HGNC:27733"
                     /db_xref="MIM:611241"
     exon            1..186
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /inference="alignment:Splign:2.1.0"
     exon            187..14037
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /inference="alignment:Splign:2.1.0"
     CDS             310..2640
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /codon_start=1
                     /product="G protein-regulated inducer of neurite outgrowth
                     3"
                     /protein_id="NP_938022.2"
                     /db_xref="CCDS:CCDS34030.1"
                     /db_xref="GeneID:285513"
                     /db_xref="HGNC:HGNC:27733"
                     /db_xref="MIM:611241"
                     /translation="MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNA
                     NGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQL
                     PGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQR
                     TSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGG
                     PEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSA
                     CPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVS
                     TSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQV
                     HIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREES
                     TAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPD
                     CKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNP
                     KSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTP
                     SRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKRVR
                     DVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTS
                     SNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD"
     regulatory      11542..11547
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="hexamer: AATAAA"
     polyA_site      11563
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="major polyA site"
     regulatory      12735..12740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="hexamer: AATAAA"
     polyA_site      12756
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="major polyA site"
     regulatory      14005..14010
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="hexamer: AATAAA"
     regulatory      14016..14021
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="hexamer: GATAAA"
     polyA_site      14031
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
     polyA_site      14037
                     /gene="GPRIN3"
                     /gene_synonym="GRIN3"
                     /note="major polyA site"
ORIGIN      
        1 gcatagtaat ttcagttcct gaacgcacgg agctcgctcc gggaccgggc tgagaaggac
       61 ctcagctcgc gggcccgccg gagccatcgg tgtggcgccg agagacggtg cttgggatat
      121 gcgacgggaa gcccccgcca cagcgcaggc agtggccccg ccgcgccgcg gagccgggca
      181 gagcaggctg gttcttcaga ggaatcatcc ctgactgtgt catcactctg agctctgact
      241 gcgctcccct cccccaccag tgggaccagt actcaagaga gctctggagt gctcctgaag
      301 agaaattcca tggggactgt acctgaccct ctgagatcag ctaaaacttc cctgattgca
      361 gcttccggaa aagaagacga tctaggagag ccacaggctg cctcacctcg gcatcgacca
      421 gctctcctgt gtaagaatgc caatggcttt tcaggtgccc ctgcagaacc agacctcagc
      481 cccagggcag ctgccgaagc cctgatgcag gtttgtgagc atgagaccac ccaaccagat
      541 atgtcttctc ctggtgtgtt caatgaagtg cagaaagcac ctgccacatt caactctccc
      601 ggcaatcccc agctgccagg gagcagccag cccgcagcat cagccccgag ttctgcagca
      661 ggaagggatc ttatacacac accattgaca atgcccgcca atcagcacac ctgccagtcc
      721 atcccaggtg atcagcccaa tgccatcacc tcatccatgc ctgaagattc cctgatgaga
      781 tcacagagaa cctcaaatag agagcaacct gagaaaccaa gttgtcctgt gggaggcgtc
      841 ctcagtagca gcaaagatca ggtgtcctgt gagtttcctt ctccagaaac aatccaggga
      901 acagtgcaga ctccagtgac agcagccagg gtggtcagtc actcatcctc tcctgtaggt
      961 ggacctgaag gggaaaggca gggagccatc tgtgactctg aaatgaggtc ctgtaaacct
     1021 ctaactagag aatctggatg ttcagagaac aagcagccct ctgtcactgc ctcgggcccc
     1081 caaggcacaa cttctgtgac acctcaacca acccccctca ctagcgaacc ttcggcatgt
     1141 cccccaggtc cagagaaggt gccgctgcca gcacagcgtc agatgtcaag gttcaaagaa
     1201 gccagtacga tgaccaacca agctgaaagt gaaatcaagg aagttcccag cagggcttgg
     1261 caagatgcgg aggtgcaggc agtggcgagt gtcgagagca gatccgtctc caccagcccc
     1321 agtatcctca ctgcatttct gaaggaaagc cgtgctcctg agcattttga acaagagcag
     1381 ctgcgtgtca tttgccacag cagtgggagc cacacactgg agctctctga cagcacgcta
     1441 gccccccagg agtccagcca gtgccctggc atcatgccac aggtgcacat tcaggcagct
     1501 gcagctgagt ctacagcttt ccaacgggaa aataaacttg cgagcctacc aggtggggtc
     1561 cttaaaacct catcaatcaa tttggtctcc agtaatgccc agcatacgtg taaagaagat
     1621 gggaggttag caggaatgac tccagtgagg gaagagtcaa ctgctaaaaa gctcgcaggt
     1681 actaattcta gctccctgaa agctaccgcc attgaccaga tttctatcag tgcatgcagt
     1741 caagctgaaa caagttatgg attggggaaa tttgaaacca ggccatctga gtttgcagag
     1801 aaaacgacaa acggccacaa aacagaccca gattgcaaac tatctgactc ttgtggctct
     1861 atcagcaaag ctgatcattc tgggagcttg gatcccacta ataaaggaga tgcaagggaa
     1921 aagaagcctg catctcctca ggtagtaaaa gaaaaagagt ctactggcac tgatacctcg
     1981 gatgccaaaa ccctactgct caatcctaaa tcccaagaaa gtggaggcac agaatcagct
     2041 gctaatccta caccctcccc aattaggaag aaccaggaga gcaccttaga agaaaacaga
     2101 cagaccaaga cagccaccag cctgagcctg ccatctgatc ccatgggtga ctccagccca
     2161 ggttctggca agaagacccc atctcgctcc gtcaaagcca gcccacgcag gcccagccgc
     2221 gtcagcgagt tcctcaagga gcaaaagtta aatgtgacag cagctgctgc tcaggtagga
     2281 ctcactccag gagataagaa aaagcagctt ggcgcagact ccaagctcca gctgaaacag
     2341 tccaagcgtg tcagggacgt cgtgtgggat gagcagggaa tgacctggga agtgtatggt
     2401 gcatccttgg acgcagagtc cctgggaatc gcgatccaga accatttgca aagacaaatc
     2461 agggaacatg agaaattaat caaaactcaa aatagccaga cccggagatc catttcctca
     2521 gatacttctt caaataagaa gctcagagga aggcagcaca gtgttttcca gtccatgctg
     2581 cagaacttcc gacgccccaa ctgctgcgtc cgtcctgccc cgtcttctgt gttagattga
     2641 aagggagtat ttatgggagt ttgtgtataa atttacggta ttcacatgcg tccctctatg
     2701 tcaaagcttg cttagttttt tgctgcaaga ctaggaagaa aaagcaagta ttcactatag
     2761 gaaattgcta ttaaaaattg ttagatcctt tgacctggag ctctataaac aaaaatgtca
     2821 tttcaatttg aaagaaggaa caagaaaaga gaaacaagct tcactgaagg tttgcaacct
     2881 taacaaattg aaaataatac tcactgggtt tttaaaaata tgatgttgtt catagaaata
     2941 gcattattgt atcattatac atgtattatt ttgtataact gcctcaattt atcacacagt
     3001 agtagttcca ttaaaatccc tgcttcatat tgaaagtagc aaaaacacta ttggcgaaaa
     3061 cattgttata atttctagtc ttattgcagt aagaatgctg taaccacaca aattataaat
     3121 aggtgataag aaccataatg aaaaaaatga gaacatattt gattcattcc taggccagat
     3181 aacattaaat aaaaacagtt aaatgtgtaa aatatgaaat atgaattaat gtttataaac
     3241 atctgcagac aactcttttt ataaaccttc ttattgctgt taataaatat aagaaagtta
     3301 tattaggaac attagctaag cttttgacta tgaaaactgc ctacattaaa catggattta
     3361 tatagaccca ttttcctgca ctgaaggcaa ggcgcatctc tgtgattctg accagacata
     3421 ttcatatttt cttaccctag aggaagtaca tgggactgaa ttcttgaaaa gagccatcaa
     3481 attagggata atactaaatt gatactgtgc aggtgttctc cagtgatatt ctactgagaa
     3541 tgctaaggtt ctggtcagga actataaata gcagattacc aaacactgct ttttctgtga
     3601 tgataaaagc ctcataagta acaaaaacaa tgtttaattt agactcctgt aaacaggatg
     3661 caattagtga ttttttttaa ttgggttcag taacttccag taacaaatgt agtcaacacc
     3721 aaattagaat gtgagcttcc ttacaatttt tgtacataga ctactatcat ctaattgctt
     3781 aaatatatat gctggagtaa aaaggtaact tctgcaaact tattgatttt aagagaaata
     3841 cccataatat ccttcaaacc caatgaaaga agaggccttt acgaaaacat ggcttgtgat
     3901 ttgggtggat tatacttcct gggaccttgg ccctcccgtg tctccagaag agacgtgtgt
     3961 cccgagacac atgagtatcc tccaaggcac tggcctggat gagcagcatc gccttgagaa
     4021 ttggggtagt gtggaaagga agaatgaaca acggccctgg gaagccttcc cttcctgcag
     4081 atattgttgg gggagtgctg gtctccattt tgcgtttaga aaaccagact tagatgctgg
     4141 aggggcaccg gttgtcttct ttgaactcat tccccgtaat gagctagaaa agagtaccta
     4201 accataggta ttctctctag agactcatgt gtcccgtggg tacagtcaat tcacagtatc
     4261 tgttctggct tttttcactt taattctgtt ctgcacattc tgaacatatg caggaaaaaa
     4321 aatcattcct gaacttagca caagctacac tcgacacaac ctaaattagt aaaaagcctt
     4381 tgatttattt tgaagcaatt taactgtaga caaagcttgc atatatggaa cagtattctc
     4441 agagcctgag agttgttaca gttgttctat ttggaaatta gaaggaattt tttaataagg
     4501 cacatttttc agtttcttac ccattggtgt ctattaagaa tactatgtaa tgttgaaatt
     4561 tccatcaaat taccaagcaa attactatta atgattagag atttagccta acactctctc
     4621 tttgggcctt aaatacccat ttgtagttgt gttcgtgtca cttctgtctc agatgcctct
     4681 gccaggacat aatctctcta actcttgcta gctggcttct ccctcccaca tgggcataca
     4741 tgctgtgtat acacagagta cagcctgtgt acacagtagc agctgtcaac agggcctact
     4801 ccagatgggt ggccccaggt aatcctctgc tgtaaagtgg ctagaacagg ctgtccctgc
     4861 attaaaatag gtgagaataa ggaatttcgc ctctgataat aatatttatt ttcatgactt
     4921 tagagtaacc acatgatttg taaacagtta aatgaagcag aggcctgaga gagttgttgg
     4981 catttgtctc acattaaata cattaaaatt gctagatttg ctattgtggt tatgtctatc
     5041 aaaactttaa gaaaatttgt ttaatgtact gagtttaact gattttcttt ggtgctggga
     5101 ccaaattctt cacttctaca acactcaaga gattgtcaca aaatattaca aaaatattgt
     5161 ttgttttgtg gctcattaaa ccctatataa ctaacagctt ttaaggacat taacagaaat
     5221 atatcttcag atggataaat aagataggga cctattcaag acagcagcat ttttgtattg
     5281 tgatacctcc cctaagttac tctcacaata aaaccttatt tgagaatttt ccttcacttc
     5341 aatctgtgac atagcattag gcatttagta taccttattt gtgaaaccta aggttcattc
     5401 aacagatgaa gctgcaaaac agttttcttg gtagactctt ggaacttgct cagttttttc
     5461 cttactttac ctgcatgaca cacattgggt tgaaagttgt ttggttttac ccttcatttc
     5521 tcttagatat gatttggttc tttttcatgc attatatttt tgaaatatat ggaggaaata
     5581 ttttattgaa tcaagaaata gaaaatattc cttaaaccag tagtaaaaag gtgagttaga
     5641 actccatgtc tggaagacaa ttcaacattt aaaatattaa gatgctatac cacttaacaa
     5701 gtgaatacta aaatttttaa tttaaagatt gattgttctg tttttatgac catgagaaaa
     5761 atgtgacagc ttcagctgtc atatgtttat cttgaatgct tttctaatta tgtatttctg
     5821 gattattgac tttgaatgcc acagaccaac tactttacat agagtaaaat attgattaac
     5881 ctttgtgctt tgggtcactg gcaaaagttg aacatcctga taagtcaatg ttaaccagaa
     5941 acctttttgt tcacgtctga aattgaatat ttataaaatg tgttagtatg tttcctgcct
     6001 tgataagttc acctatattg aatgtaattt gatctttgat aatttttttt aatcttgaga
     6061 attctctgat actgttttga ataccagtgt tcaccatgtt ataaagttaa acataaaaat
     6121 tgaaataaat tgaactaaat atgcatgtgt aacatatacc ttagaggttg gatttcagaa
     6181 ccaaattcat aataggagct tgctgtctta aagtagaaag cagaagagga aaatagcatt
     6241 tgtttgtatt ctagcatatt gaggtttcac tgttcctagc ttatactaat gtttttcctc
     6301 tcatttctgg gaatgcctgt cattctgaga atccctatat atagcatacc aagaacagag
     6361 tatgatgtta ctttaaaatg tgtttacaga ggatatatgc aagtgtgctg ttaatataaa
     6421 ttgtttgtcc ttttctgcat ccactttgtt actgttttgc tgccaaaatg tgtgaaatgt
     6481 gtgtcttctc ttcctcctac atattgtgcc aagtgtttaa aattttgtct actcctagta
     6541 acacataatt aaccacatcc cttgtctact tttatgaatc agtataaaga aaaacaatac
     6601 attaggataa ggtttgcata tatgtatatg tgtttttatt gaaaactggg cacttgtagc
     6661 cttgtgtaga cctctacctg cctgatttac taattatctg taatgctgcc atggagatga
     6721 tgctgtttac tctctcctgc tttgttctaa gtggtgtttg agaagtgagg cctgtgaatt
     6781 tccctttgtg gtagaacagt gaactcagca gtatcttgca taagtgagcc gactacctta
     6841 ttcccactct gtttttgtgt acatggtgaa atcagaagtc aaacatcccc tttagtgttt
     6901 gttattttac atatgtatct gagcattttg ttttctgtta gcaatgcttc ctgatgttgt
     6961 gcgtggccct ttttggttga ttctctccaa attcgggtca gctgctgcca cctggcaaat
     7021 aacagaggat atgctgaatc tcctgtccat ccttgtaacg atatccttct taatgaaatt
     7081 cttcaactgg ctgagcaatt acaaatgtca tctgtccaga cacatgggct taaggatgtc
     7141 tacaaaattt tagacatttt tgcaaatggg aaaaaaaata gtcttgtaaa tactgaaaca
     7201 gatttccatg aactttatcc tactcttgga aagaaaacaa ttctccttgg ctgcagaaat
     7261 caaataagct gggtttgcaa tgaccaagga cataaatgaa gatggattga agtggaaaaa
     7321 ttctgtctcc caagtgatca gtgacatctg ccagaggtca ttacagctac ttttaactgt
     7381 gaacagtcac cagctaaact actcacttgc cacaacaaaa taacctctct caaaataaat
     7441 ccagtgcatc tgtatatatg tgtagatagc agcaacaaac aatcctgaaa cattattttt
     7501 ggctgttagg taagtaaacg tgatgataat tataaacaac attcaaataa ccttggacct
     7561 tggtgaaatg acttgtggtg gccagaatgg tgcaacaaga tgttatttgc aagttttttt
     7621 aagacacaaa tatctcagat actaataatg agaataaaga ctgttgaata tgaaattaaa
     7681 gccaagcaat aatgtgccaa aaagaggcag ttataccagc aaatgcatct attatgggca
     7741 caccattata taatgatggt ttgctttatg aagactgact gtaacccaca ggataaaata
     7801 agcaaaggca tagtttctgc tttcttcctg gaaaaacttg tttagaagct tcataaagag
     7861 gtacagcact aatgagcatt agtcaggata cagttggcat ctatgttttt atgtgagccc
     7921 agagggaaga ggagccactc aaagtcttgc tggcttaaaa ctcaagacag ctgcaaccag
     7981 aagttttgtt gaaatggaga ctttaaactt atggtaatta ctctttctgg acactagcat
     8041 gtagaaagca attcagttaa ctctgcccag aggattacca gctttagctg tgaaaaaatg
     8101 ggctcccgga tgtaaaatca ctaaaacatg agatcttgta tccaaagagg cttcaaatga
     8161 tgccttacag aaaacgatgc tccagatggg cacttctaaa tgctaactct tcatcaagta
     8221 tctttctgga ttcaagctca aaattaattg gctgcaaaat agtaggaata aaaatcacat
     8281 attttacact ttagaaaagg atattgatga tcaacctgca tggtgataat tatgatgaga
     8341 taccccagtg atttaatgat gttagaaaga attaaatggg agagaattgc taacagcttt
     8401 cttgatctct taactatgga gatgtcattc atttatttct ggggtgaaaa ttatagcttg
     8461 ctttttgaca ttgctgctag tattgttctt tgttgcttta aaaattgtct ctctttagaa
     8521 aaactcttga gcagttaaac agtttttttt ctgattcata tcattgcttt taataacatg
     8581 taaaggctgt gtgtagagca aactatataa aatgagtaga aagggcttac tcatgttaat
     8641 tggcatcctt gatgatttta gttgagattc cttaacattt attttagatc acatctttac
     8701 gtaacttatt tttcctaatg ttttccatcg tgtcttaaaa tgatgctggt atatcaggag
     8761 attgcagtat tatagtcata ctccccaatc cctagaggag aggaaagact aattcttgtt
     8821 ttaagggccc ctggagatac cttttattaa ggttgaaaaa ggtcaacaca gcctgaaaat
     8881 aagaaaaata tatactagca attactaatt ttctaaatgt gtgtatctct gctgtactaa
     8941 tgtgtgaaca atatgtcgtg cataatactg tagctggtcg tggtatgtca atacattctg
     9001 tgagtgtgta cagtctgagt gatcagtttt ctatttttat gtgtaaaaaa aataacttgt
     9061 cgtatcccat ttaaaggcca atttctgtat tcaggcaggc atatgtacat acatgaataa
     9121 agccaacaaa agtgtgcaca tgtattcagt aacagaattt gtccttttat ttttgaaggt
     9181 cagaaagggc tgtttgattt gtgttttttt tttatcatct ccttgagtag gtaacataat
     9241 tatcacaaag gctgaatata gtaatcagta cattggcata ttattaaata tgccagggct
     9301 aagtaaccat gccattagtc acaggtaagg tcagttcttt gaccactggg ataatttaca
     9361 ttcctcacac atcctctccg tgttaagtgt gtgactagga tgtacatact atgggtgtga
     9421 ttgtgtacat accttgtatg aattatctaa atcctcaaag cagttgcagg aaagaaggaa
     9481 gatgaaacag ttgttcaaaa gcctcaaaag ggctaatcaa tatatatttt tcattttcta
     9541 cacataaaaa tgtaaatagc ttatccacat atataggcac acataataca ttttatttat
     9601 actagtatat tcagataaat cacaaattaa aaccactaat tgaaagttgc atatttccat
     9661 gactgctctg ttttacaaat attattattg aatgagatgc ccccccaatt aatggtgtta
     9721 ctccctggta gcagattttg tgcttagaaa actccagcaa ctgaagcaca gactggtaac
     9781 tgagtagcta cagggaatta atgcttctct ttaagcacct aatttcatat ctggaaatgg
     9841 caaacaggga tgaaaatcga ttatgttttg gagactcctt ttggacatgt atcagtgtgt
     9901 tgatttgcac aaaccaataa aagccctaca ttttttggaa atggatccct agatttcaag
     9961 catgtataat cactcaaagt ggatatgatc acaggcattc ttctcttgag ctcagcaaaa
    10021 ctatgcctac caacaccgaa gagaagtcaa agatttaaat gaaaaaaaat tgcagatgat
    10081 gttggtgaga taataggata tgagcaatga acccttgggt ggggttccag ggcacttaaa
    10141 ttgcctcgtg tcttgagttc cttaagatgg actcaaacaa aaaattagta ttatcaataa
    10201 caggtaatac tgtgtggatt ctaacaacat tagaatcatt agctggcaag tgtcaactct
    10261 gaacaagatt tgtcagctta tcataattcc aaccagttaa ttgatattgt tcgaatttat
    10321 ctcatttttt ctcaaaggaa gtgctctatt agggatcaaa aagtctcacc tggttcttaa
    10381 aacctaacac aatttgacct tgaatcctcg acactaaaaa ttacgttggt tgggtatcag
    10441 attgaaaata tgcatggagg ctgggcgtgg tggctcacac ctgcaatccc agcactttgg
    10501 gaggccaagg caggcagatc acctgaggtc aggagttcaa gaccagcctg gccaacatgg
    10561 caaaaccccg tctctactaa aaatacaaaa actagccggg catggtggtg tgtgcctgta
    10621 atcccagcta ctcgggaggc tgaggtggga gaatcacttg aacctgggaa gcagaggttg
    10681 cagtgagcca agttcgcgcc attgcactcc agcctgggag acagggcaag gctctgtctc
    10741 aaaaaaaaga aaatataaat ggaaatacca gaatcacccc ttgatagaga attccatttg
    10801 gcaaagtaca aacaaccact tctcagtaga aagttaagaa taacatttaa aaacatattc
    10861 atgttttaga gaacgaatgt gccatcgttg tatattaaat aaaaataaaa gattaaccag
    10921 ctataagaac actacaatta caactagagt ggcagtgttt tttaactaat aaaagtatac
    10981 atgtttataa gtgcagcata cctgaaatct tgatgtttgt caatacttat ggttgcttca
    11041 aagataaatt tatgtgatta tttttgaaag atgtgtatta atttgaataa tacccagaaa
    11101 aattataact taaaaattgc agttttcaat atgagaatca tttatgtgtg taaatactca
    11161 actaagaaag atcaaaagtg tggtataata ttacaagaaa aaatattcaa aatggaaagt
    11221 ccatttatga atgtattaat attaaaatcc aaagttatgt ttttttataa tgtctacatt
    11281 ataatgttta caaaggccat aaaatcattt cagaaagttc tcatcctcca gatattgacc
    11341 aataaaactt catttcctag aaaaaagaag aaatgttata atttatacaa agatgaagta
    11401 agattttgga attacgtata cttacacctt cattttggat ttgatttttg aatggatgct
    11461 taaaattctg atattcaact aatgacttag ttttaccatc aaaaaattta gattatgatt
    11521 tttttgcatc tcacttttca taataaatgt aatatagata caatttattc tgttttttgt
    11581 tgatgttatt attgtttcca ctgctattga aatcgttctt ttaaccatga atgtgcagaa
    11641 tcagttgatt ttccatgtga cagcttctgc taggaatctg cagtggaact ggaagtattt
    11701 gcaatgaaag aacttttttc tttaattaaa atagaattcc catagaatca acaattcctc
    11761 ctggtcatca aacgcgaggt ttttcctgta cttggtagag cagagtgtgt gtgtgtttgt
    11821 gcgttgtgtg tgtgttgttt ggtgagaatg atgagagctg agcattgtga aaatacaggc
    11881 gggggtgggg taacagagct gggtaggggt ccagggcgct tagattgcct tattgtccag
    11941 gcttagatgc ctcttaccca gagccatcag gtgtacccta tatagctcca gcctttctgc
    12001 ctactcctga gaagataaac tgggatcctg cagtctggat tcctagaagg agatggaaag
    12061 cccagccata tccccagttt gacttgacca gtagtaaaac tagcactaca gtttgatccc
    12121 tttttacctc cttgaatatc ttcaattcat caaggatctg taaagaagga gaggtacaag
    12181 atatatgaaa cccaaatctc aaaacaatga tttagtgaat ttcccatgaa ctttaaacag
    12241 tgattgcttc aaaatttcca agagccatac tctccctcca gctgctgtgt gtgtgtgtgt
    12301 gtataaatgc acactatttt aacctaaaat ggtgccctgt ggctgccatt ctctaactct
    12361 tgcatactta aacatttatt cttggtcaaa ttaaaacctc atgcatttcc aaagatataa
    12421 atgccttgcc tggagaagtt agatcttgca agtctcagga gggccgagat ggtttgtctt
    12481 atgcctatag ctgtttatgt cccaccagtg ggtgtttgtt tcattaggtg ccgtttccag
    12541 ccaaatgttc tcattcttca catcttcaat gttgagtagc aaacagaaga acatccttct
    12601 tagcataata ttgcttcact ggactgattg tgaactcaaa atacctcttg tttcttgtga
    12661 agggtttgcc ttttgtaaac aatataagat cacttttggt caaccaccct gtctgaattt
    12721 atctgggctg ctataataaa gtatcataaa ctgggaggct tgtaaataaa tttatttctt
    12781 acagttttgg aagctgggaa ccccaaaatc aaggccaatt tggtgtctgg tgagggccta
    12841 cttgccggct cacgtgtggt gcctgtttgc tgtgtcctca cacagtaaaa gggatgaagt
    12901 gtcccctccc gggccacttt caaaagggca ctaatctcac tcatgagggc tctgtgacca
    12961 ccatctaatc accacccaaa gcccccactt tctaacacca tcgccttagg agttcagact
    13021 tcaacatgag ttttggaggg atacagacat ttagaccatg gcatacacat tcttaatgaa
    13081 cttctgaatg ccaccattat taaattttct tcaacaccat tctacacaac cactgagcta
    13141 attgacagag ttctaaaatg tttagaccct tgtaactacc ttagcaatgt tctgaagctg
    13201 gtttttctaa atatatcaca gaggtctaac atagttgaaa ttcaaattgt ctggatggaa
    13261 gctgaaagtg cttgcagaga tttctggtgg gagtactggc atctcaagaa tggtatttcc
    13321 ctacaccttt tttagtcccg cttgacgtct ctcaatcaaa ctgcaaaaga gccttgacct
    13381 gccattaaaa ataataataa gcagaatgtc attgccaaag attattatag gtgtttaaaa
    13441 gcaagataag acttcttaaa gggctccaaa gcatttgctt gttatctatg tttttttagc
    13501 ccaaagccaa aacaaaaaat aatgcctttg tgccagacgt tttgctgggc acttccatct
    13561 atgtctcaac cttaggaggt ataatgtata catgcacagt tttacaattt gtcaatggca
    13621 cagatacttg agacatataa attggatgat cacagagata ttgtggtaaa tatctgggct
    13681 tggaatcaaa ggaccctggg ttcaaatctc agcttcgaat caaagaagct aaattctttg
    13741 gctgagtaaa ccaaaacacc tcccaccaga ccccacctcc aaatttcaac atgaaatttg
    13801 gagaggataa atatccaaat tatttcagtg cattcatctg gaaactgaga ataacaatgc
    13861 tcactttgca aatttgtggg aattaaatgg cataggcaaa atattgttct tttcttctct
    13921 tactcctctg agttttgctt tcttccactt gaactttacc actcaattgt taaaagcctt
    13981 gaattttgcc attgtattct atttaataaa cttttgataa atctggataa ataataa
//
