LOCUS       NM_052899               4234 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens G protein regulated inducer of neurite outgrowth 1
            (GPRIN1), mRNA.
ACCESSION   NM_052899
VERSION     NM_052899.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4234)
  AUTHORS   Zhou,Q., Li,D., Zheng,H., He,Z., Qian,F., Wu,X., Yin,Z., Bao,P.T.
            and Jin,M.
  TITLE     A novel lncRNA-miRNA-mRNA competing endogenous RNA regulatory
            network in lung adenocarcinoma and kidney renal papillary cell
            carcinoma
  JOURNAL   Thorac Cancer 12 (19), 2526-2536 (2021)
   PUBMED   34453499
  REMARK    GeneRIF: A novel lncRNA-miRNA-mRNA competing endogenous RNA
            regulatory network in lung adenocarcinoma and kidney renal
            papillary cell carcinoma.
REFERENCE   2  (bases 1 to 4234)
  AUTHORS   Nordman,J.C., Phillips,W.S., Kodama,N., Clark,S.G., Del Negro,C.A.
            and Kabbani,N.
  TITLE     Axon targeting of the alpha 7 nicotinic receptor in developing
            hippocampal neurons by Gprin1 regulates growth
  JOURNAL   J Neurochem 129 (4), 649-662 (2014)
   PUBMED   24350810
REFERENCE   3  (bases 1 to 4234)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   4  (bases 1 to 4234)
  AUTHORS   Iida,N. and Kozasa,T.
  TITLE     Identification and biochemical analysis of GRIN1 and GRIN2
  JOURNAL   Methods Enzymol 390, 475-483 (2004)
   PUBMED   15488195
REFERENCE   5  (bases 1 to 4234)
  AUTHORS   Chen,L.T., Gilman,A.G. and Kozasa,T.
  TITLE     A candidate target for G protein action in brain
  JOURNAL   J Biol Chem 274 (38), 26931-26938 (1999)
   PUBMED   10480904
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC091934.2.
            
            On Nov 22, 2018 this sequence version replaced NM_052899.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC052950.1, SRR1163655.661507.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1968540
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000303991.5/ ENSP00000305839.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                AC091934.2         53012-53037
            27-158              AC091934.2         53038-53169
            159-4234            AC091934.2         63291-67366
FEATURES             Location/Qualifiers
     source          1..4234
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q35.2"
     gene            1..4234
                     /gene="GPRIN1"
                     /gene_synonym="GRIN1"
                     /note="G protein regulated inducer of neurite outgrowth 1"
                     /db_xref="GeneID:114787"
                     /db_xref="HGNC:HGNC:24835"
                     /db_xref="MIM:611239"
     exon            1..158
                     /gene="GPRIN1"
                     /gene_synonym="GRIN1"
                     /inference="alignment:Splign:2.1.0"
     exon            159..4234
                     /gene="GPRIN1"
                     /gene_synonym="GRIN1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4217..4222
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPRIN1"
                     /gene_synonym="GRIN1"
                     /note="hexamer: AATAAA"
     polyA_site      4234
                     /gene="GPRIN1"
                     /gene_synonym="GRIN1"
                     /note="major polyA site"
ORIGIN      
        1 gcgggagcgc ggagccggcg ctggggacgg cggcgccgag tctgcgggtc ctcccgccag
       61 cccggccgga ggcagccgag gccgctcggg cggcggcggc ggcggcggcg ggagccggag
      121 cgcatctcgc ccaggagccg gagcagcggc actgcctgaa ccagacagca gccttgggtg
      181 caggcgtggt catgagggca gatggacact gctgaagacc cggcctggct ccagctgctt
      241 caaaaggatt ccagcccccc aggaccccga cccacagcct tcttctgccc acaggatggg
      301 agcctggggg ctggcagctc ggctatgagg gattactgcc cctcccagca aaaggcaagc
      361 cctgcacccc ccaggcacac ccctgaccaa agcccaggca tggagtctag acacagaagc
      421 cccagtgggg ctggggaagg ggcctcctgc tctgacggcc ccagagggag cctggcctgc
      481 ccctccccaa cctgcttctc tccccaggag tcaccctcca aggagacatt ggaggcacat
      541 ggagcctcca tctcagggac accagaagcc accacgtctg ggaagccaga gcctgtgtcc
      601 tccgtgaaaa ctgagcccaa atcctcagat gacagaaatc ccatgttctt agagaagatg
      661 gatttcaagt cctcaaagca ggccgattcc acttccatag gaaaggagga tcctgggtcc
      721 tcacggaagg cagatcccat gtttacagga aaggcagagc ctgaaatctt gggaaagggg
      781 gatcctgtgg ctcctggaag gatggatccc atgactgtaa gaaaggaaga tcttggatcc
      841 ctgggaaaag tagatccttt gtgctccagc aagacgtata cagtgtcacc gaggaaggag
      901 gatcctgggt ctttgagaaa ggtggatcct gtgtcctcag acaaagtgga ccctgtattc
      961 ccaagaaagg aggagcccag gtattcagga aaagagcatc ctgtgtcctc agaaaaggtc
     1021 gctcctacat ctgcagaaaa ggtagatctt gtattgtcgg gaaagagaga tcctgggccc
     1081 tcgggaaagg cagatcccat gcccttggaa agcatggatt ctgcgtccac aggaaagaca
     1141 gagccggggc tcctgggcaa gctgattcca ggctcatcag gcaagaatgg gcctgtatcc
     1201 tctgggaccg gggctcctgg gtccttggga aggctggatc ccacatgctt ggggatggca
     1261 gatcccgcat ctgtgggaaa tgtagaaact gtgcctgcca caaaagagga ctcccggttc
     1321 ctgggaaaga tggaccctgc ctcctcagga gaggggcgtc ctgtgtctgg ccacacggat
     1381 actacggctt cagcaaagac agatctcaca tctttgaaaa atgtggatcc catgtcttca
     1441 ggcaaggtgg atccagtttc tctgggaaag atggacccca tgtgctcagg aaagccagag
     1501 ctcttgtctc ctggacaggc agagcgtgtg tctgtgggaa aggcaggaac tgtatcccca
     1561 ggaaaagagg acccggtgtc ctccagaagg gaggacccca tatctgctgg aagtagaaag
     1621 acatcatctg aaaaagtgaa tcctgagtct tcaggaaaga caaaccctgt gtcttcaggt
     1681 ccaggcgatc ccaggtcctt ggggacagca ggtcccccat ctgcagtaaa ggctgagcca
     1741 gcgacggggg gaaaaggaga tcccctgtcc tcggagaagg caggtctggt ggcctctgga
     1801 aaggcggctc ccacagcctc agggaaggcc gagcccctcg cggtgggcaa ggaggaccct
     1861 gtgagcaagg gaaaggcaga cgctggcccc tctggacaag gggactctgt gtctataggt
     1921 aaagtggtct caactccagg aaaaacagtc ccggtgccct cggggaaggt ggatcccgtg
     1981 tccctgggaa aagcagaagc tatcccagag ggaaaagtgg gttctctgcc tctagagaag
     2041 gggagtcctg ttaccaccac aaaggcggat cccagggcct cggggaaagc acagccgcag
     2101 tctggtggca aagcagaaac aaagctccct gggcaagagg gcgctgcagc accaggggaa
     2161 gcaggggctg tgtgtttgaa aaaggagaca ccacaggcct cagagaaggt ggatcctgga
     2221 tcctgcagaa aagcagagcc ccttgcctca gggaagggag agcctgtgtc cctggggaaa
     2281 gccgactctg caccttccag aaaaacggag tccccatcct tggggaaggt ggtccccctg
     2341 agtctggaga agaccaagcc gtcctcctcc tccaggcagt tagaccgcaa agccctcggc
     2401 tcagcccggt ctcccgaggg tgccaggggc agtgaaggcc gcgtggagcc gaaggccgag
     2461 cccgtgtcca gcaccgaggc ctccagtctc ggccagaaag acctggaagc cgctggggcc
     2521 gagagaagcc cctgcccaga ggccgcagcg cccccgccgg ggccgcggac tcgcgacaac
     2581 ttcaccaagg cgccgtcgtg ggaggcgagc gccccgccgc cgccgcgcga ggacgcgggc
     2641 actcaggcgg gcgcgcaggc ctgcgtctca gtggccgtga gccccatgtc tccgcaggac
     2701 ggcgctgggg gctcggcctt cagcttccag gcggcgccgc gcgcgcccag cccgccctcg
     2761 cgccgagatg cgggcctgca ggtgtcgctg ggcgccgccg agacgcgctc cgtggccact
     2821 gggcccatga cacctcaagc cgccgcgccg cccgccttcc ccgaagtgcg ggtgcggccc
     2881 ggctcagcgc tggcggccgc tgtagcgccc ccggagccgg ctgagcccgt gcgagacgtg
     2941 agctgggacg agaagggcat gacgtgggag gtatacggcg ccgccatgga ggtggaggtg
     3001 ctgggcatgg ccatccagaa gcatctggag cgacagatcg aggagcacgg ccgccaaggg
     3061 gcgcccgcgc cgccgcccgc cgcccgtgcc ggccccggcc gttcgggctc ggtgcgcacc
     3121 gcgcccccag atggcgccgc caagcgtccg cccggcctgt tccgcgcgct gctgcagagt
     3181 gtgcgccggc cgcggtgctg ctcgcgggcg ggacccacgg ccgagtgatc tgcccccatt
     3241 ttgtacgccc gagtttccga ccttctcagg ctcccttctt gatcacaggc ccctagaagg
     3301 ggtcccctct gcgtgccaca ggcctccgag gggttgtgca gcctctaggg ctgttgcgtc
     3361 cccgtctttc cagcccctcc catcacaaat acagaagaac cccttctacc aagctccctc
     3421 gtggccacga ggccacgaac ccggccagcc ctgacgcccc actgtcccct cacagccctc
     3481 agctctactc ccggtcacac tgggcgacca cgggggcctg ctcagcaccc tcacctccca
     3541 ccccctgaga gctggggcag gctcctgaga tgtctagact ggtgcgttgt ggtctccggt
     3601 ggggccagat ccccagaaca gggagagact gcatacaagt ctgagtggca gaagcttcaa
     3661 gtgggtgagg atcggtgtgt gagacccgcg agtgggcacg tctctgaatg tgaggtctcg
     3721 ggcagcacgt gaggtagaac gagtgtgagc gtctccacgc agtggctggc cccgtggccg
     3781 gggcgtctct tgcatgctgt tggtggtcct tccccagttc ctatctccca cccgcctggt
     3841 tccagcccca tcccctctcc cactgagtca caggtttgag attcccagag aggccaaaga
     3901 cagctacagg aagtaccctg ggggctcagc tgagagagag tcacagaaag gccagagggt
     3961 ctcaggaagg tctggaggtc acagctgggc tcacagaagc tcttgggccc tggcatcctg
     4021 ggtgaccggt gttcttgggt attggggaca ggacagagag ctcattctat aaccacagtt
     4081 gtcttttaaa ggccaccctc tccagcccct tgtcccccct gtgctgtgag cccaagtccc
     4141 ttgtgaccac tcagtgtccc gtccccaccc ctccagccgc agtttttggc tacaaactgt
     4201 cacagtatac attggtaata aaatatttcc ccaa
//
