LOCUS       NM_080865               2119 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens G protein-coupled receptor 62 (GPR62), mRNA.
ACCESSION   NM_080865
VERSION     NM_080865.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2119)
  AUTHORS   Oishi,A., Karamitri,A., Gerbier,R., Lahuna,O., Ahmad,R. and
            Jockers,R.
  TITLE     Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2
            receptor reciprocally modulate their signaling functions
  JOURNAL   Sci Rep 7 (1), 8990 (2017)
   PUBMED   28827538
  REMARK    GeneRIF: Collectively, these data show that GPR61, GPR62 and GPR135
            are unable to bind melatonin, but show a reciprocal regulatory
            interaction with MT2 receptors.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2119)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   3  (bases 1 to 2119)
  AUTHORS   Takeda,S., Kadowaki,S., Haga,T., Takaesu,H. and Mitaku,S.
  TITLE     Identification of G protein-coupled receptor genes from the human
            genome sequence
  JOURNAL   FEBS Lett 520 (1-3), 97-101 (2002)
   PUBMED   12044878
  REMARK    Erratum:[FEBS Lett 2002 Jul 17;523(1-3):257]
REFERENCE   4  (bases 1 to 2119)
  AUTHORS   Lee,D.K., George,S.R., Cheng,R., Nguyen,T., Liu,Y., Brown,M.,
            Lynch,K.R. and O'Dowd,B.F.
  TITLE     Identification of four novel human G protein-coupled receptors
            expressed in the brain
  JOURNAL   Brain Res Mol Brain Res 86 (1-2), 13-22 (2001)
   PUBMED   11165367
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115284.4 and BC026357.1.
            
            On Nov 23, 2018 this sequence version replaced NM_080865.3.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC026357.1, AB032600.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000322241.6/ ENSP00000319250.4
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-966               AC115284.4         37268-38233
            967-2119            BC026357.1         967-2119
FEATURES             Location/Qualifiers
     source          1..2119
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.2"
     gene            1..2119
                     /gene="GPR62"
                     /gene_synonym="GPCR8; KPG_005"
                     /note="G protein-coupled receptor 62"
                     /db_xref="GeneID:118442"
                     /db_xref="HGNC:HGNC:13301"
                     /db_xref="MIM:606917"
     exon            1..2119
                     /gene="GPR62"
                     /gene_synonym="GPCR8; KPG_005"
                     /inference="alignment:Splign:2.1.0"
     CDS             273..1379
                     /gene="GPR62"
                     /gene_synonym="GPCR8; KPG_005"
                     /note="probable G-protein coupled receptor 62; hGPCR8;
                     G-protein coupled receptor GPCR8; G-protein coupled
                     receptor KPG_005"
                     /codon_start=1
                     /product="G-protein coupled receptor 62"
                     /protein_id="NP_543141.3"
                     /db_xref="CCDS:CCDS2838.1"
                     /db_xref="GeneID:118442"
                     /db_xref="HGNC:HGNC:13301"
                     /db_xref="MIM:606917"
                     /translation="MANSTGLNASEVAGSLGLILAAVVEVGALLGNGALLVVVLRTPG
                     LRDALYLAHLCVVDLLAAASIMPLGLLAAPPPGLGRVRLGPAPCRAARFLSAALLPAC
                     TLGVAALGLARYRLIVHPLRPGSRPPPVLVLTAVWAAAGLLGALSLLGTPPAPPPAPA
                     RCSVLAGGLGPFRPLWALLAFALPALLLLGAYGGIFVVARRAALRPPRPARGSRLHSD
                     SLDSRLSILPPLRPRLPGGKAALAPALAVGQFAACWLPYGCACLAPAARAAEAEAAVT
                     WVAYSAFAAHPFLYGLLQRPVRLALGRLSRRALPGPVRACTPQAWHPRALLQCLQRPP
                     EGPAVGPSEAPEQTPELAGGRSPAYQGPPESSLS"
     polyA_site      2072
                     /gene="GPR62"
                     /gene_synonym="GPCR8; KPG_005"
     polyA_site      2119
                     /gene="GPR62"
                     /gene_synonym="GPCR8; KPG_005"
                     /note="major polyA site"
ORIGIN      
        1 agtaccatct ccgacagggg ctgagttgct ggagctgggc tggggcaggg gagaaagaca
       61 gcagactcat ccttgcaccc ctccatgggc ctggccaagc ccccaagagg atggcagcct
      121 gggcgtcgga gccacctcct gggcagccaa tgaggtgagg ggccggagga gcaagggaca
      181 agaggagcag aggacaggtg atggaaatcc tgcagcttta ggctccattc tgccatctac
      241 atcccagcgc agggtgaagc ctgagagccc aaatggccaa ctccacaggg ctgaacgcct
      301 cagaagtcgc aggctcgttg gggttgatcc tggcagctgt cgtggaggtg ggggcactgc
      361 tgggcaacgg cgcgctgctg gtcgtggtgc tgcgcacgcc gggactgcgc gacgcgctct
      421 acctggcgca cctgtgcgtc gtggacctgc tggcggccgc ctccatcatg ccgctgggcc
      481 tgctggccgc accgccgccc gggctgggcc gcgtgcgcct gggccccgcg ccatgccgcg
      541 ccgctcgctt cctctccgcc gctctgctgc cggcctgcac gctcggggtg gccgcacttg
      601 gcctggcacg ctaccgcctc atcgtgcacc cgctgcggcc aggctcgcgg ccgccgcctg
      661 tgctcgtgct caccgccgtg tgggccgcgg cgggactgct gggcgcgctc tccctgctcg
      721 gcacgccgcc cgcaccgccc cctgctcctg ctcgctgctc ggtcctggct gggggcctcg
      781 ggcccttccg gccgctctgg gccctgctgg ccttcgcgct gcccgccctc ctgctgctcg
      841 gcgcctacgg cggcatcttc gtggtggcgc gtcgcgctgc cctgaggccc ccacggccgg
      901 cgcgcgggtc ccgactccac tcggactctc tggatagccg cctttccatc ttgccgccgc
      961 tccggcctcg cctgcccggg ggcaaggcgg ccctggcccc agcgctggcc gtgggccaat
     1021 ttgcagcctg ctggctgcct tatggctgcg cgtgcctggc gcccgcagcg cgggccgcgg
     1081 aagccgaagc ggctgtcacc tgggtcgcct actcggcctt cgcggctcac cccttcctgt
     1141 acgggctgct gcagcgcccc gtgcgcttgg cactgggccg cctctctcgc cgtgcactgc
     1201 ctggacctgt gcgggcctgc actccgcaag cctggcaccc gcgggcactc ttgcaatgcc
     1261 tccagagacc cccagagggc cctgccgtag gcccttctga ggctccagaa cagacccccg
     1321 agttggcagg agggcggagc cccgcatacc aggggccacc tgagagttct ctctcctgag
     1381 caggagaaag gagggtggtt tccgtggggg ctcatccaac ccctgcacag gtcacagcag
     1441 gtgccctgct ggatatctgg gtctggaaca ggaggagaaa gggtgtctgc tgcctggtga
     1501 ggcccacgga cttctgagag ccaggaatcc tgcggtctgg gcccaacact gcatagcact
     1561 gtgcataggc cgacccttcc ttaggcctca gctttcccat ctgcaccctg cagcatctct
     1621 aagggcccct ccagcatagg tggtttgtga aactcacagg tggtccccag gccaagatgg
     1681 gcaggtgtca caaagaagag ggccctaagg gctcacaacc aaagtgatcc gccaagcagg
     1741 gcagtatctg ggttacagcc acagcaggaa gaaccactgg agagacactc agaaggactt
     1801 ccctgacatc tgcaccaagg agagtctgga caaagctact gaaactcctc cacctgcttc
     1861 taaaatgccc agaagacaac tggaccagtt tggtattaga agtaggaggc tggacgactt
     1921 cacccccaaa gggtcctgaa gccccagaac tggcatgtgg aaggggctga ggcctaattg
     1981 aggttggtgg attcacacat gggggtcctc caggacctca gctgcaccca ttttctggag
     2041 gttttgctgc ccacaacacc agtatttcac aacttcctgg tcgctgagaa tatttattca
     2101 aaaacaggga ttgaaaaaa
//
