LOCUS       NM_024980               5197 bp    mRNA    linear   PRI 24-JUN-2024
DEFINITION  Homo sapiens G protein-coupled receptor 157 (GPR157), mRNA.
ACCESSION   NM_024980 XM_375687
VERSION     NM_024980.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5197)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 5197)
  AUTHORS   Gregory,S.G., Barlow,K.F., McLay,K.E., Kaul,R., Swarbreck,D.,
            Dunham,A., Scott,C.E., Howe,K.L., Woodfine,K., Spencer,C.C.,
            Jones,M.C., Gillson,C., Searle,S., Zhou,Y., Kokocinski,F.,
            McDonald,L., Evans,R., Phillips,K., Atkinson,A., Cooper,R.,
            Jones,C., Hall,R.E., Andrews,T.D., Lloyd,C., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Anderson,F., Andrew,R.W., Ashwell,R.I.,
            Aubin,K., Babbage,A.K., Bagguley,C.L., Bailey,J., Beasley,H.,
            Bethel,G., Bird,C.P., Bray-Allen,S., Brown,J.Y., Brown,A.J.,
            Buckley,D., Burton,J., Bye,J., Carder,C., Chapman,J.C., Clark,S.Y.,
            Clarke,G., Clee,C., Cobley,V., Collier,R.E., Corby,N.,
            Coville,G.J., Davies,J., Deadman,R., Dunn,M., Earthrowl,M.,
            Ellington,A.G., Errington,H., Frankish,A., Frankland,J., French,L.,
            Garner,P., Garnett,J., Gay,L., Ghori,M.R., Gibson,R., Gilby,L.M.,
            Gillett,W., Glithero,R.J., Grafham,D.V., Griffiths,C.,
            Griffiths-Jones,S., Grocock,R., Hammond,S., Harrison,E.S., Hart,E.,
            Haugen,E., Heath,P.D., Holmes,S., Holt,K., Howden,P.J., Hunt,A.R.,
            Hunt,S.E., Hunter,G., Isherwood,J., James,R., Johnson,C.,
            Johnson,D., Joy,A., Kay,M., Kershaw,J.K., Kibukawa,M.,
            Kimberley,A.M., King,A., Knights,A.J., Lad,H., Laird,G., Lawlor,S.,
            Leongamornlert,D.A., Lloyd,D.M., Loveland,J., Lovell,J., Lush,M.J.,
            Lyne,R., Martin,S., Mashreghi-Mohammadi,M., Matthews,L.,
            Matthews,N.S., McLaren,S., Milne,S., Mistry,S., Moore,M.J.,
            Nickerson,T., O'Dell,C.N., Oliver,K., Palmeiri,A., Palmer,S.A.,
            Parker,A., Patel,D., Pearce,A.V., Peck,A.I., Pelan,S., Phelps,K.,
            Phillimore,B.J., Plumb,R., Rajan,J., Raymond,C., Rouse,G.,
            Saenphimmachak,C., Sehra,H.K., Sheridan,E., Shownkeen,R., Sims,S.,
            Skuce,C.D., Smith,M., Steward,C., Subramanian,S., Sycamore,N.,
            Tracey,A., Tromans,A., Van Helmond,Z., Wall,M., Wallis,J.M.,
            White,S., Whitehead,S.L., Wilkinson,J.E., Willey,D.L., Williams,H.,
            Wilming,L., Wray,P.W., Wu,Z., Coulson,A., Vaudin,M., Sulston,J.E.,
            Durbin,R., Hubbard,T., Wooster,R., Dunham,I., Carter,N.P.,
            McVean,G., Ross,M.T., Harrow,J., Olson,M.V., Beck,S., Rogers,J.,
            Bentley,D.R., Banerjee,R., Bryant,S.P., Burford,D.C., Burrill,W.D.,
            Clegg,S.M., Dhami,P., Dovey,O., Faulkner,L.M., Gribble,S.M.,
            Langford,C.F., Pandian,R.D., Porter,K.M. and Prigmore,E.
  TITLE     The DNA sequence and biological annotation of human chromosome 1
  JOURNAL   Nature 441 (7091), 315-321 (2006)
   PUBMED   16710414
  REMARK    Erratum:[Nature. 2006 Oct 26;443(7114):1013. Banerjee, R [added];
            Bryant, SP [added]; Burford, DC [added]; Burrill, WDH [added];
            Clegg, SM [added]; Dhami, P [added]; Dovey, O [added]; Faulkner, LM
            [added]; Gribble, SM [added]; Langford, CF [added]; Pandian, RD
            [added]; Porter, KM [added]; Prigmore, E]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY768808.1 and AL158048.35.
            
            On Nov 23, 2018 this sequence version replaced NM_024980.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK292888.1, AY768808.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377411.5/ ENSP00000366628.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               AY768808.1         69-555
            488-492             AL158048.35        21661-21665
            493-683             AY768808.1         561-751
            684-728             AL158048.35        27452-27496
            729-1085            AY768808.1         797-1153
            1086-5197           AL158048.35        28705-32816
FEATURES             Location/Qualifiers
     source          1..5197
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.22"
     gene            1..5197
                     /gene="GPR157"
                     /note="G protein-coupled receptor 157"
                     /db_xref="GeneID:80045"
                     /db_xref="HGNC:HGNC:23687"
                     /db_xref="MIM:620860"
     exon            1..458
                     /gene="GPR157"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1083
                     /gene="GPR157"
                     /note="probable G-protein coupled receptor 157"
                     /codon_start=1
                     /product="G-protein coupled receptor 157"
                     /protein_id="NP_079256.4"
                     /db_xref="CCDS:CCDS100.2"
                     /db_xref="GeneID:80045"
                     /db_xref="HGNC:HGNC:23687"
                     /db_xref="MIM:620860"
                     /translation="MQPSPPPTELVPSERAVVLLSCALSALGSGLLVATHALWPDLRS
                     RARRLLLFLSLADLLSAASYFYGVLQNFAGPSWDCVLQGALSTFANTSSFFWTVAIAL
                     YLYLSIVRAARGPRTDRLLWAFHVVSWGVPLVITVAAVALKKIGYDASDVSVGWCWID
                     LEAKDHVLWMLLTGKLWEMLAYVLLPLLYLLVRKHINRAHTALSEYRPILSQEHRLLR
                     HSSMADKKLVLIPLIFIGLRVWSTVRFVLTLCGSPAVQTPVLVVLHGIGNTFQGGANC
                     IMFVLCTRAVRTRLFSLCCCCCSSQPPTKSPAGTPKAPAPSKPGESQESQGTPGELPS
                     T"
     exon            459..672
                     /gene="GPR157"
                     /inference="alignment:Splign:2.1.0"
     exon            673..867
                     /gene="GPR157"
                     /inference="alignment:Splign:2.1.0"
     exon            868..5197
                     /gene="GPR157"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5178..5183
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPR157"
                     /note="hexamer: AATAAA"
     polyA_site      5197
                     /gene="GPR157"
                     /note="major polyA site"
ORIGIN      
        1 agacggcggc ggcgtggccg cacgcgcggc ccggcttctg tcctcgcggc gctccggctc
       61 ctggcccccc acgccatgca gccgtccccg ccgcccaccg agctggtgcc gtcggagcgc
      121 gccgtggtgc tgctgtcgtg cgcactctcc gcgctcggct cgggcctgct ggtggccacg
      181 cacgccctgt ggcccgacct gcgcagccgg gcacggcgcc tgctgctctt cctgtcgctg
      241 gccgacctgc tctcggccgc ctcctacttc tacggagtgc tgcagaactt cgcgggcccg
      301 tcgtgggact gcgtgctgca gggcgcgctg tccaccttcg ccaacaccag ctccttcttc
      361 tggaccgtgg ccattgcgct ctacttgtac ctcagcatcg tccgcgccgc gcgcgggcct
      421 cgcacagatc gcctgctttg ggccttccat gtcgtcagct ggggggtccc gttggtcatc
      481 actgtggcag ccgtcgccct gaagaagatt ggctatgacg cctcggacgt gtctgtgggc
      541 tggtgctgga tcgacctgga ggccaaggac catgtcctgt ggatgctgct gacggggaag
      601 ctgtgggaga tgctggcata tgtgctgctg cctctgctgt acctcctggt ccggaagcac
      661 atcaacagag cgcacacggc actctctgag taccggccca tcctctccca ggagcaccgc
      721 ctgctgcgcc actcctccat ggcggacaag aagctggtgc tcatcccgct catcttcatc
      781 ggcctcaggg tctggagcac cgtgcggttc gtgctgaccc tctgtggctc cccggccgtg
      841 cagacgccgg tgctggtggt tctgcatggt atcgggaaca cgtttcaggg aggtgccaac
      901 tgcatcatgt tcgtcctctg cacccgcgcc gtccgaactc ggctcttctc tctctgttgc
      961 tgctgctgct cttctcagcc tcccaccaag agcccggctg gcactcccaa ggctcccgcg
     1021 ccttccaagc caggagaatc tcaggaatcc caagggaccc caggggaact tccaagcacc
     1081 tgagcttttg tcctttctag ttctgtgcat aggtgctgcc ttcctggggg taggcacttc
     1141 tgtgagtccc tgctgcaggg gcagaagtgc atgtctgctg caccagaagc ccccgctatt
     1201 gatgctctcg gctccattgg gagagcagct gccaactcag cttcttctac ctcctagatc
     1261 ctcaggcagc aagttccacc ggtaccagcg tcctggccca cgggtgggcg ttcatctgca
     1321 taagggtagc agtgagattc gggaagccgg tggcccacag ctgtggccac agtgccccca
     1381 cccagtggac cttgatgtcc tgaggaccac acagcactgt ttacaatctg agggacccac
     1441 atctgtgcac ctatcctctg tgtgattaaa taagctgtca ggggccctca gagatgtgtc
     1501 cccatccaca catcatggag cagattcccg gctggtcagg gtgttaagat tctctggaga
     1561 acccggcttt ccttggagac tttgctcaac agaggaacca gttgccattc accaggttga
     1621 aggttcccct gaggttgcat ggtgaccacc aggggcaagc acagcccggc gcagctgctc
     1681 agggacagca gtctccccgg gcctcctggc ctctccctcc atgggctgct aacccttgcc
     1741 gtagcttggg tttgagtgtc aagcacaggc cagaatccac actcctgtcc ccacctgtca
     1801 atcacttcag acacaggttc cctccttcca attccaaagc tggaacaagg gcaggaagag
     1861 gcgtctcagg gaacccccga agaccccact gtctctccag ctcctttctt agaatcctcc
     1921 tcttcttggg gagaccaaag gggatgagta gggaggggtt ctggcttatt tacttcttag
     1981 tttagttttt tgtaagtaaa gtggccggag agatgagtaa tccaaatacg attcctcagg
     2041 ccgggcacag tggctcacac ctgtaaccct agcactttgg gaggccaagg caggcagatc
     2101 acctgaggtc aggagttcaa gaccagcctg gccaacatgg tgaaaccctg tctctactaa
     2161 aaatacaaaa attagccagg catggtgatg cacgtctgta atcccaggtc tttgggaggc
     2221 tgaggcagga gaatctcttg aacctgggag gcggaggttg cggtgagcca agaccacacc
     2281 attgcactcc agcctgggca acaagagtga aactcggtct caaacaaaca aatacgattt
     2341 cttcctaaag gtgaaggttt taagcttcag agtcagtttt tttttttttt tttttttaaa
     2401 aaaggagcct cattctgtcg cccggagctg atgtggtggt gcgtgcctgt agtccctact
     2461 actcaggagg ctgagacggg aggatccctt gagcccaggg atttgaggct tcattgaact
     2521 gggatggcac cactgccact ccagcctggg caacagcagg accctgtctc aaaaaaagaa
     2581 aaaaacaaag gattcaaaag gattcagctg ttttgtattc agctgaggta agtggcggca
     2641 tggagcatgg agcgattatt tacatttaaa agaaaagaat tgaaagtaag cacctgtatc
     2701 tctattttta ttctgtgggt cttccacaaa cgctttcgtc ttatttcaga aaacagcttc
     2761 tgtgttcagt cacaggagcc atcggcaaag aatggaagtg gaaatgctac ctccagggtc
     2821 ttggtgagag aaagtacagc tttacctgat aggtgatttc ccttggaatc catcagaact
     2881 cgacaaagca tgattttctg agcctagtaa aatggttctg aatcaaaacc gaagtcacgc
     2941 tgtgctgccg atccctgttt gactctcaaa accaaaatct gtatcaggaa aggaataatc
     3001 atttagcaga ctgagtccaa aatgctcatt tttggtttcc tgtgaaaatg gatttctttt
     3061 tgtcgctttc tttttttttt tttttttttt tgagatggag tctcactcta ttgcccaggc
     3121 tggagtgcag tggtgcaatt ttgactcact gcaaccaccg cctcccaggt tcaagcgatt
     3181 ctcctgcttc ccaatcccaa gctgctggga ttacaggcat gcgccaccat gctcggctaa
     3241 ttttttgtat tttcagtaga gacgggtttt caccatgttg gccaggctgg tctcgaactc
     3301 ctgacctcag gtgatccacc cacctcagcc tcccaaaatg cttcgattgc aggcatgagc
     3361 cactgtgcct gtccaagaaa acagatttct tgatggaaat tagtgagaca gacatcccct
     3421 taggattgaa agagagctct gggctgctcc agggaaagcc acttggcaga aatagcctct
     3481 gtaagtgaat tctggattcc cctgaagacg ttacagcaaa tctctgggta tgtctctggt
     3541 aaagaccctc acttgagctt ctagaaggga gcgaaaattc aggaatttgc ttgctgcaaa
     3601 agagaacatg attaacaggt aaaagagaaa agacaatata ggccacagag gaatagtgtt
     3661 aggatcaacc ctgctcagca ggggcctctg gagccctccc tgctgtaccc aagccagagc
     3721 tgagacatgg ctccccagat ggactggctg tggtcaggaa aggcctgtag agggagctga
     3781 gggctcagaa aatacctgct ccgggtgcct gggctcaagt tctcattcca tttctttgat
     3841 gccactggcc actgtatctg cttttgtaaa aacctccaaa aagttataca tcaggtatct
     3901 ctagtcagct tcctccgctg cccacctctt gccacagatg agtgatcact gtgaatggtg
     3961 gtgaccaggt gggcagggca ggggcttgtc taagtgcctt agcccaggcc cctggcccat
     4021 cgacctcgaa aacagcaata tcgcctcctt cttagatcca gttaccaagt cagtctagct
     4081 gggtgggtag tgctcagaca gaaaggctgg atgggaagga agtcacatcc taaaagtcca
     4141 ggagggggcc aggcgcagtg gctcacgcct gtaatcccag cactttggga gaccaaggtg
     4201 ggcagatcac ctgaggtcag gagtttgaga ccagcctggc caacatggtg aaaccctgtt
     4261 tctactaaat atacaaaaaa aaaaaaaata gttggatgtg gtttcgtgtg cctgtagtgc
     4321 cagctactca ggaggctgag gcaggagaat tgcttgaacc cagaaggcag aggttgcagt
     4381 gagccgagac tgcaccactg cactccagcc tgggtgacag agcaagactc catctcaaaa
     4441 aataaaacaa gtccaggagg ggctgttact tctttttagt ttatttattt ttgtgaggca
     4501 gggttttgct gtctggagca tcatacccag tctggagtgc agtgatgcaa tcatggctca
     4561 ctgcagcctc cacctcccag gctcaagcga tcctcccacc tcagctccct gagaagctgg
     4621 gaccacaggc ctggctaaat tttgactttt tgtagagaca aggttttgcc atgttgccca
     4681 gtcagatctc aagcgagggg ctgttacatc tgatcagggc aaaaggggct gtgctccttg
     4741 gacactttgc acagccccag tgggcttctt tctcctctgt tagtgtggtt aatgttcatc
     4801 tgcctgcatc cctgagtcac ccaagtgtaa cctcagccat aacacgtact gcagccggaa
     4861 cggtgtccgc agctcagcgt ccctctccca tgcactttct gaactttggt cttttaacca
     4921 ggtttaccag ccgctttctg cctctttgtg cttttgaggg ttttttggtt tgtttgttct
     4981 gttttgtttt taaataaaga tgattatttg gcccaggctg agggtgcaaa cagaactctt
     5041 cacgtgtcca cgacaagaaa aatagttttt acaaacttct agttgtggca tcaaaagtgt
     5101 gagtttttgc acctgcaaaa ttgtaatgca agccctgact gggtggaagc tgaagtcttg
     5161 ctgttttaaa ttaaataaat aaattatttt tctccta
//
