LOCUS       NM_152529               7346 bp    mRNA    linear   PRI 17-JAN-2025
DEFINITION  Homo sapiens G protein-coupled receptor 155 (GPR155), transcript
            variant 3, mRNA.
ACCESSION   NM_152529
VERSION     NM_152529.7
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7346)
  AUTHORS   Bayly-Jones,C., Lupton,C.J., Keen,A.C., Dong,S., Mastos,C., Luo,W.,
            Qian,C., Jones,G.D., Venugopal,H., Chang,Y.G., Clarke,R.J.,
            Halls,M.L. and Ellisdon,A.M.
  TITLE     LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR
  JOURNAL   Nature 634 (8036), 1238-1244 (2024)
   PUBMED   39358511
REFERENCE   2  (bases 1 to 7346)
  AUTHORS   Liu,L., Li,X., Song,L., Yang,Y. and Li,B.
  TITLE     Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit gastric
            adenocarcinoma malignant characteristics by targeting miR-223-3p
  JOURNAL   Pathol Res Pract 257, 155325 (2024)
   PUBMED   38678850
  REMARK    GeneRIF: Circular RNA hsa_circ_0094976 modulates GPR155 to inhibit
            gastric adenocarcinoma malignant characteristics by targeting
            miR-223-3p.
REFERENCE   3  (bases 1 to 7346)
  AUTHORS   Shin,H.R., Citron,Y.R., Wang,L., Tribouillard,L., Goul,C.S.,
            Stipp,R., Sugasawa,Y., Jain,A., Samson,N., Lim,C.Y., Davis,O.B.,
            Castaneda-Carpio,D., Qian,M., Nomura,D.K., Perera,R.M., Park,E.,
            Covey,D.F., Laplante,M., Evers,A.S. and Zoncu,R.
  TITLE     Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency
            to mTORC1
  JOURNAL   Science 377 (6612), 1290-1298 (2022)
   PUBMED   36007018
  REMARK    GeneRIF: Lysosomal GPCR-like protein LYCHOS signals cholesterol
            sufficiency to mTORC1.
REFERENCE   4  (bases 1 to 7346)
  AUTHORS   Umeda,S., Kanda,M., Sugimoto,H., Tanaka,H., Hayashi,M., Yamada,S.,
            Fujii,T., Takami,H., Niwa,Y., Iwata,N., Tanaka,C., Kobayashi,D.,
            Fujiwara,M. and Kodera,Y.
  TITLE     Downregulation of GPR155 as a prognostic factor after curative
            resection of hepatocellular carcinoma
  JOURNAL   BMC Cancer 17 (1), 610 (2017)
   PUBMED   28863781
  REMARK    GeneRIF: Downregulation of GPR155 may serve as a prognosticator
            that also predicts initial recurrence sites independent of
            hepatitis virus infection.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7346)
  AUTHORS   Shimizu,D., Kanda,M., Tanaka,H., Kobayashi,D., Tanaka,C.,
            Hayashi,M., Iwata,N., Niwa,Y., Takami,H., Yamada,S., Fujii,T.,
            Nakayama,G., Fujiwara,M. and Kodera,Y.
  TITLE     GPR155 Serves as a Predictive Biomarker for Hematogenous Metastasis
            in Patients with Gastric Cancer
  JOURNAL   Sci Rep 7, 42089 (2017)
   PUBMED   28165032
  REMARK    GeneRIF: GPR155 may represent a biomarker for diagnosing and
            predicting hematogenous metastasis of gastric cancer.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 7346)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   7  (bases 1 to 7346)
  AUTHORS   Nishimura,Y., Martin,C.L., Vazquez-Lopez,A., Spence,S.J.,
            Alvarez-Retuerto,A.I., Sigman,M., Steindler,C., Pellegrini,S.,
            Schanen,N.C., Warren,S.T. and Geschwind,D.H.
  TITLE     Genome-wide expression profiling of lymphoblastoid cell lines
            distinguishes different forms of autism and reveals shared pathways
  JOURNAL   Hum Mol Genet 16 (14), 1682-1698 (2007)
   PUBMED   17519220
REFERENCE   8  (bases 1 to 7346)
  AUTHORS   Vassilatis,D.K., Hohmann,J.G., Zeng,H., Li,F., Ranchalis,J.E.,
            Mortrud,M.T., Brown,A., Rodriguez,S.S., Weller,J.R., Wright,A.C.,
            Bergmann,J.E. and Gaitanaris,G.A.
  TITLE     The G protein-coupled receptor repertoires of human and mouse
  JOURNAL   Proc Natl Acad Sci U S A 100 (8), 4903-4908 (2003)
   PUBMED   12679517
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK315125.1 and AC018470.11.
            
            On Jun 2, 2019 this sequence version replaced NM_152529.6.
            
            Transcript Variant: This variant (3) differs in the 5' UTR,
            compared to variant 1. Variants 1, 2 and 3 encode the same isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK315125.1, BX537947.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000392552.7/ ENSP00000376335.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2647              AK315125.1         1-2647
            2648-7346           AC018470.11        127216-131914       c
FEATURES             Location/Qualifiers
     source          1..7346
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q31.1"
     gene            1..7346
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /note="G protein-coupled receptor 155"
                     /db_xref="GeneID:151556"
                     /db_xref="HGNC:HGNC:22951"
                     /db_xref="MIM:620855"
     exon            1..157
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            158..648
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     CDS             189..2801
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /note="isoform 1 is encoded by transcript variant 3;
                     integral membrane protein GPR155; G-protein coupled
                     receptor PGR22; lysosomal cholesterol signaling protein"
                     /codon_start=1
                     /product="lysosomal cholesterol signaling protein isoform
                     1"
                     /protein_id="NP_689742.4"
                     /db_xref="CCDS:CCDS2259.1"
                     /db_xref="GeneID:151556"
                     /db_xref="HGNC:HGNC:22951"
                     /db_xref="MIM:620855"
                     /translation="MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFP
                     ALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSF
                     LYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQT
                     TYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNP
                     IVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAF
                     VVLILLITAKLLVLPLLCREMVELLDKGDSVVNHTSLSNYAFLYGVFPVAPGVAIFAT
                     QFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLI
                     SLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKNFVGQILVFVLL
                     YSSLYSTYLWTGLLAISLFLLKKRERVQIPVGIIIISGWGIPALLVGVLLITGKHNGD
                     SIDSAFFYGKEQMITTAVTLFCSILIAGISLMCMNQTAQAGSYEGFDQSQSHKVVEPG
                     NTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFE
                     KNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFN
                     QEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWNNKDTAENRD
                     SPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASD
                     RGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYK
                     EIEHSSPPSHSPKT"
     exon            649..1048
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1214
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1215..1370
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1371..1454
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1455..1572
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1573..1657
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1658..1748
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1749..1959
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            1960..2064
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            2065..2201
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            2202..2297
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2362
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            2363..2500
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     exon            2501..7346
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6655..6660
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /note="hexamer: AATAAA"
     polyA_site      6679
                     /gene="GPR155"
                     /gene_synonym="DEP.7; DEPDC3; LYCHOS; PGR22"
                     /note="major polyA site"
ORIGIN      
        1 actttatcgg aacgtgccta agctgctgca gctggcaccc ggttgcgctc ggcgaagagg
       61 gctgggggcg ggagatgacg gtggtcttct ccctgcttgg caccctgcga gcaccagctc
      121 ccttctcctc gccactccaa ggttgcagac gaagcagaga tctggttgga gttggagggt
      181 gagagaaaat gaattctaat ttacctgcag agaacttaac cattgcagtc aatatgacca
      241 agactttgcc tacagcagta acgcatggat ttaattccac taatgaccca ccttcaatgt
      301 caattacaag gctttttcca gccttactgg aatgctttgg cattgtcctt tgtggctaca
      361 tagcaggaag ggccaatgtc ataacatcaa cccaggccaa aggactagga aattttgtct
      421 ccagatttgc acttccagct ttattattca aaaacatggt tgtacttaat ttttccaatg
      481 tggactggtc cttcctatat agtatcttaa ttgccaaagc ttctgtattt ttcattgtat
      541 gtgtattaac cttattggtt gccagtcctg atagtcgatt tagcaaagct ggactattcc
      601 ctatttttgc tacacaaagt aatgactttg cattgggata ccctatagtt gaagctttat
      661 atcaaactac atacccagaa tatctccagt acatttattt ggtggcacca atatctctta
      721 tgatgttaaa ccctataggg tttattttct gtgaaatcca aaagtggaaa gacactcaaa
      781 atgcttctca aaataaaata aaaattgtgg gactcggact cctgcgtgta ttacagaacc
      841 caatagtatt tatggtcttc attggcatcg ccttcaattt tattcttgat cgaaaggtac
      901 ctgtatatgt cgaaaatttt cttgatggac ttggaaattc tttttctgga tcagccctat
      961 tttatcttgg tctcacgatg gtgggaaaaa taaagagact gaagaagtcg gcatttgtag
     1021 tactaattct tctcatcaca gctaaacttc tggtgctgcc acttctgtgc agagaaatgg
     1081 tggaactctt ggacaagggc gacagtgtgg tgaaccatac aagtttatca aattatgcat
     1141 ttctgtatgg tgtatttcct gtagcaccag gagtggctat ctttgcaaca caattcaaca
     1201 tggaagtaga aattataacc tcagggatgg tgataagcac atttgtgtct gctcccatca
     1261 tgtacgtttc tgcctggtta ctgacctttc ccactatgga ccctaagcca ttggcatatg
     1321 ccatccagaa tgttagtttt gatataagta ttgtcagcct gatctccttg atctggtctc
     1381 tggctattct tcttttgagt aagaaatata aacagcttcc tcatatgctt acaactaatt
     1441 tactcattgc tcagtctatt gtctgtgctg gaatgatgat atggaatttt gttaaagaaa
     1501 aaaattttgt tggacaaatt ttggtgtttg ttctattgta cagctccctc tatagcacct
     1561 acctgtggac aggccttcta gcaatttctt tgtttctttt gaaaaagcga gagagggtac
     1621 aaattcctgt tggaataatc ataatatctg gctggggaat tcctgctctc cttgttggtg
     1681 ttcttttgat aactggaaaa cacaatggag atagcattga ctcagccttc ttttatggaa
     1741 aagaacagat gatcaccaca gcagtcaccc tgttctgcag catcctgata gctggcatat
     1801 ccctcatgtg catgaaccag actgcccaag caggaagcta tgaaggtttc gatcagtctc
     1861 agagccacaa agtggtggag cctggaaata ctgcttttga ggagagtcca gcaccagtaa
     1921 atgaaccaga actttttaca agctctattc cagaaacaag ttgctgctcc tgctccatgg
     1981 gaaatggtga attacactgc ccatcaatag agccaatagc aaacacaagc accagtgagc
     2041 ctgtgattcc ttcgtttgag aaaaacaatc attgtgtgag tcgctgtaac tcccagagct
     2101 gcatattagc ccaggaagaa gaacagtatc tacagagtgg agaccagcaa ctgacccgac
     2161 atgtgttgct gtgtttactt ctcatcattg gcctgttcgc taatctttcc agttgtttat
     2221 ggtggctatt caaccaagag cctggaagac tttatgttga gttacagttt ttctgtgccg
     2281 tgtttaactt tggtcaggga tttatttcct ttggaatctt tggattagat aaacatttaa
     2341 tcatcctgcc tttcaaaaga agacttgaat tcctatggaa caataaagac acagcagaaa
     2401 acagggattc tcctgtttca gaggaaataa aaatgacctg tcaacaattt atccattatc
     2461 accgtgacct ctgtatccga aacattgtca aagaaagaag gtgtggtgca aagacttctg
     2521 ctggaacttt ctgtggctgt gacctggtga gctggctaat tgaagtcggc cttgcctccg
     2581 accgtggtga agctgtgata tacggagaca ggctggtaca agggggagtc atccaacata
     2641 ttaccaacga gtatgaattc cgggatgagt acttgtttta cagatttctt caaaagagtc
     2701 ctgaacagag tcctcctgct attaatgcaa acactctcca acaggaaaga tataaagaaa
     2761 ttgagcattc atccccaccc tcacattccc ctaagaccta aattatgcag gggagaaccc
     2821 tacatggaat catattctag ccgcgtattc attagttttt agctgggtga ccttgggcaa
     2881 gttaacagag gcaacctctc tgagcctcag ttgtctcttc tgtaaaatgt gaaaagatgt
     2941 gctcccacca catgcgcagg gtctgtgatt ttacatgtat gtaaaacaca taggaagctg
     3001 acttaggaaa aagagaaaac caaattaaag ttctgataat gaatataata tagtcatcct
     3061 ttagtatcca aggggattgg ttccaggact cctgaagatc ccaaaatctg aggatactca
     3121 agtcccttat ataaaatggt gtaggccggg catggtggct cacgcctgta atcccagtac
     3181 tttgggaggc cgagtcaggt ggatcacctg aggtcaggag ttcaagacca gcctggccaa
     3241 catggcgaaa ccccgtctct actataaaat acaaaaaatt agttgggtgt ggtggcgggt
     3301 gcctgtaatc ccagctactc aggaggctga ggcaggagaa tcgcttgaat ctgggaggca
     3361 gaggttgctg tgagccgaga tcgtgccact gcactccagc ctgagcaaca gagcaagact
     3421 ctatctcaaa aataaaataa aataaaataa aataattaat aaaatggtgt agtatttgca
     3481 tataacctat gcacattctc ccatatagtt taatcatctt tagatactta taatgcctaa
     3541 tacaatgtaa atgctatgta aatagttgtt gttatactgt attgtttagg gaataacaat
     3601 aagaaaaaca gtctgtacat gttcactaca gatgcaacca ttgttaagcc tgactacatc
     3661 tttttatctg cggttgattg aatctatgga tgtggaacct gtgcatatgg agggtcaact
     3721 gtactataaa taatacgaat atgccaacat tatataatca ttgctttctg caactgttta
     3781 ctataatttc aaaattaata tcctattaac tgttcctata aattatcaaa tttggcaagt
     3841 gtattactag caggagatgg accttaaatt atgacaactt tatatttttt gatagcatct
     3901 cttgaaaaag aattttaatg attctaataa gaggttcttt ttcttttttc catttccttg
     3961 acaaatagta ctcatttaaa aactagaggg ctaggcttag tggctcacgc ctgtaatctc
     4021 agcactttgg gaggctgagg cgggcagatc gcttgaggtc aggagttcaa gaccagcccg
     4081 ggcaacgtgg tgaaacccgg tctgtactaa aaaaaaaaaa aaagaaaaag aaaaagaaaa
     4141 aagaataccc aggtgtggta gtgcatgcct gtagtcccag ctactttgga gactgaggtg
     4201 ggagtacccc ttgagcctgg gaggcgcagg ttgcagtgaa ccaagatcac atcactgcac
     4261 ttcaacctgg gtgacagagc aagaccctgt ctcaaaaaca aaaaacaagc aaaaaaaacc
     4321 tagaggcact attttttttt aaagtttgtc ttttcttttc tacccaaatt actaatctat
     4381 gccattaagg aaaggaataa gaacctccat atgtattatt atctccacag tcctgcagaa
     4441 gtacaatctg atctttaact ttcatgctac aaataataat ttgagtagat taatttgaat
     4501 tttatcaaca aaattattgc catatgatgt atcatttctg tgtttgaaca aagcatcgta
     4561 atgcaggata acttctactt tattccctgt agttaaaaaa aaaaaaacta tatagttcaa
     4621 gccaatattt aaaaattcta aacctaggct gggcatggtg actcatacct gtaatcccag
     4681 cactttggga ggccgaggca ggtgaattgc ttcagcccag gagttcgaga ccagcctggc
     4741 caatgtggtg aaaccccatc tctactaaaa aaaaaaaaaa aaaaaaaaat tagccaggtg
     4801 tggtggtgtg cacctgtaat cccagctacc caggaggctg aggcaggaaa attgcttgaa
     4861 accaggaggc agaggttgca gtgagctgag atcgtgccac tgcactccag cctgagtgtc
     4921 agagtgagac tctgtctcag aaaaaaaaaa aaaaattcta aagattacat ttagaattta
     4981 gtctttttaa agtgtccatg tataaaaata tataattttt aaaattacta aatgttgcct
     5041 tttctcttag tctaatattt tagctactaa aacaaaatat aaactggata gcttataaac
     5101 aacataaact tatttctcac agttttggag gctgtgaagt ccaagattaa ggcactaaca
     5161 gatctagtgt ctggtaaggc aaatttctgg ctcatagatg gtaccttctt gctgtgtccc
     5221 cacatggtag atgggaagaa ctggtctcat tggcccctta taaggacatt aattccactc
     5281 aataggctcc accctcatga tctaataacc tctcaaaggc cctacctcct aatactaaca
     5341 cattgaggat gtgacttcaa ctttacattt ctacaggcag agaagtgggg ctgtgtaaat
     5401 tcttcccatc agtacttgaa tgttcattta acaaataact tatcgagcat ctagcatgtt
     5461 ccagacacaa tctgaacact gagcacacaa cagttggaac aaatatgatt cctatcctca
     5521 tggagcttct attctcctgt gaaaaacaga tgttaaacat gattgaggat taggtttcaa
     5581 cataagaatt ctaggaggac acagacattt agaccatagc atcttcaggt aaactttatc
     5641 ttcagtaaat taaagagatc tatttagatg acctttgagc atcttaatta ttagatgtca
     5701 gtgctagttt aacttatttt aaacgtttca gatatttatt taattatact ttaagtgtct
     5761 catgtaaaaa agttatttat aaaataattt atagggttag agtcattgcc cttttaatgc
     5821 aacaaataaa cagtttttta aaaacctgca tgggggccag gcgcggtggt tcatacctgc
     5881 aatcccagca ctttgggagg tcgaggctgg cggatcacga ggtcaggaga tcgagaccac
     5941 cctgattaat gcggtgaaat cccgtctcta ctaaaaatac aaaaaattag ccagacgtgg
     6001 tggtgggcac ctatagtccc agctactcgg gaggctgagg caggagaatg gcatgaaccc
     6061 ggaaggcgga gcttgcagtg aaccaagatc gcgccactgc actccagcct gggcgacaga
     6121 gtgagactcc atcgcaaaaa aaaaaaaaaa aaaacctgca tggaagccta gtatatttat
     6181 taataacaaa taaattatac tttagtgtac tattaaccta taccaatttt aagttgtgat
     6241 tagggaatgg ggatgttttt aagctgaatt gtcttgctgc ggaactttcc ttttttaata
     6301 agaccatatt atgactctga atgctcaagg gtaagtctaa ggcctcattg ctgttaccag
     6361 gagatttttc tagttacagt aataaagatg ttaattcaca tgcatgcaga caactgaaac
     6421 tcaagtggag aatttgtttg tgaacaagtc atactacttc tgttatttgc atgaatggaa
     6481 tctgcaatat ctttttccat gggagaccct aaaagaaaac cctggatcag aatgatctgc
     6541 agtttcagat aataaaggct tttaagagac atttttagaa ttaaaaatat gctaatttta
     6601 ttaaatgaaa atatttgtaa ctgttaactt tctcactgac aaagcaagtt tctcaataaa
     6661 atacctattt taacttgcat tactgacatc ttttctttga gtaatctgaa taatgcagaa
     6721 gccatcatag aggtcttttc tatacattct caatgttttc ttaaatgggt ttcctgagtt
     6781 ctgttcttca tgactctggg ctctgcaaac agggtttccc aattacgcat tctataaaca
     6841 cttttatgaa tgagtcaata tgacattgag tccttttcat acatttcatc atttccaata
     6901 tgtagagtga cagctagaaa aatgataaaa ttttgattaa aacctatctc tttttcttca
     6961 gcatagtcaa ttgttttctt aactctcaat gagtaactcc atgcctagct tgtgcttagc
     7021 tttcaatatt tttagactaa gacaaagtgt atttggcatt ttgagaacaa caattaatgg
     7081 tcagtaaatt tctaaagcaa gaaaaatgtg aaactagtgt tttatatgtt tgttacgcag
     7141 cagaatgcgg ctcttagtgt ttgccccttc atatctcatc atgtaaaata ttaaattact
     7201 ttaggccact gcacataggt agtcctgtca tgagtgatgg ctggagaaaa gttcaggatc
     7261 ataaatgtta tcatcattct tcaagaaaag atgagattat aaatttctgc aattggtatg
     7321 ataaaaggtt gaaataatta atgaaa
//
