LOCUS       NM_017926              14021 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens G-patch domain containing 2 like (GPATCH2L),
            transcript variant 1, mRNA.
ACCESSION   NM_017926
VERSION     NM_017926.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 14021)
  AUTHORS   Chen,Z., Song,J., Xie,L., Xu,G., Zheng,C., Xia,X., Lu,F., Ma,X.,
            Zou,F., Jiang,J. and Wang,H.
  TITLE     N6-methyladenosine hypomethylation of circGPATCH2L regulates DNA
            damage and apoptosis through TRIM28 in intervertebral disc
            degeneration
  JOURNAL   Cell Death Differ 30 (8), 1957-1972 (2023)
   PUBMED   37438603
  REMARK    GeneRIF: N6-methyladenosine hypomethylation of circGPATCH2L
            regulates DNA damage and apoptosis through TRIM28 in intervertebral
            disc degeneration.
REFERENCE   2  (bases 1 to 14021)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 14021)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 14021)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 14021)
  AUTHORS   Weimann,M., Grossmann,A., Woodsmith,J., Ozkan,Z., Birth,P.,
            Meierhofer,D., Benlasfer,N., Valovka,T., Timmermann,B.,
            Wanker,E.E., Sauer,S. and Stelzl,U.
  TITLE     A Y2H-seq approach defines the human protein methyltransferase
            interactome
  JOURNAL   Nat Methods 10 (4), 339-342 (2013)
   PUBMED   23455924
REFERENCE   6  (bases 1 to 14021)
  AUTHORS   Levy,D., Larson,M.G., Benjamin,E.J., Newton-Cheh,C., Wang,T.J.,
            Hwang,S.J., Vasan,R.S. and Mitchell,G.F.
  TITLE     Framingham Heart Study 100K Project: genome-wide associations for
            blood pressure and arterial stiffness
  JOURNAL   BMC Med Genet 8 Suppl 1 (Suppl 1), S3 (2007)
   PUBMED   17903302
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC016526.6, AB032978.1 and AK000696.1.
            
            On May 17, 2019 this sequence version replaced NM_017926.3.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.96264.1,
                                           SRR1803611.239451.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000261530.12/ ENSP00000261530.7
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                AC016526.6         34710-34721
            13-803              AB032978.1         1-791
            804-1111            AK000696.1         779-1086
            1112-1112           AC016526.6         59458-59458
            1113-1690           AK000696.1         1087-1664
            1691-14021          AC016526.6         84801-97131
FEATURES             Location/Qualifiers
     source          1..14021
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.3"
     gene            1..14021
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /note="G-patch domain containing 2 like"
                     /db_xref="GeneID:55668"
                     /db_xref="HGNC:HGNC:20210"
     exon            1..70
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            71..742
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..1529
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /note="isoform 1 is encoded by transcript variant 1; G
                     patch domain-containing protein 2-like"
                     /codon_start=1
                     /product="G patch domain-containing protein 2-like isoform
                     1"
                     /protein_id="NP_060396.2"
                     /db_xref="CCDS:CCDS9848.1"
                     /db_xref="GeneID:55668"
                     /db_xref="HGNC:HGNC:20210"
                     /translation="MDELVHDLASALEQTSEQNKLGELWEEMALSPRQQRRQLRKRRG
                     RKRRSDFTHLAEHTCCYSEASESSLDEATKDCREVAPVTNFSDSDDTMVAKRHPALNA
                     IVKSKQHSWHESDSFTENAPCRPLRRRRKVKRVTSEVAASLQQKLKVSDWSYERGCRF
                     KSAKKQRLSRWKENTPWTSSGHGLCESAENRTFLSKTGRKERMECETDEQKQGSDENM
                     SECETSSVCSSSDTGLFTNDEGRQGDDEQSDWFYEGECVPGFTVPNLLPKWAPDHCSE
                     VERMDSGLDKFSDSTFLLPSRPAQRGYHTRLNRLPGAAARCLRKGRRRLVGKETSINT
                     LGTERISHIISDPRQKEKNKALASDFPHISACAHEFNPLSPLYSLDVLADASHRRCSP
                     AHCSARQANVHWGPPCSRDIKRKRKPVATASLSSPSAVHMDAVEPTTPASQAPKSPSS
                     EWLVRTSAAEKATDATTATFFKMPQEKSPGYS"
     exon            743..807
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            808..984
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1064
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            1065..1132
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1187
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            1188..1273
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1368
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..14021
                     /gene="GPATCH2L"
                     /gene_synonym="C14orf118"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagagggaa gccccggcgg tgagagtcgg cccaaaaagc ggcggccgtt ggaggtggct
       61 gcggcagctg atgtggcctc atggatgagc tggtacacga cttagcctca gccttggagc
      121 agacatctga gcagaataag cttggtgaac tgtgggagga gatggcgctg agcccccgac
      181 agcagaggcg gcagcttcgg aaacgccgag gtcggaagcg tcgttctgac ttcactcacc
      241 tggcagagca tacctgctgc tacagcgagg cctctgagtc aagtctggat gaggccacta
      301 aggactgtcg agaagtggct ccggtgacca attttagtga ctctgatgac acaatggtag
      361 ccaaacgaca cccagctctc aatgccattg tcaagagtaa gcaacattct tggcatgaat
      421 ctgactcctt tactgaaaat gcaccttgtc gaccactcag gcgcaggcgg aaggtgaagc
      481 gagtgacatc agaggtggct gctagccttc agcagaagct gaaggtgtca gattggagct
      541 atgagagagg ctgcaggttc aagtctgcta agaagcagcg tctgtcccgc tggaaggaga
      601 atactccctg gacctcatca ggccacggat tgtgtgaatc agcagaaaat aggactttcc
      661 taagcaaaac aggaaggaaa gaaaggatgg agtgtgaaac agatgaacaa aaacagggct
      721 ctgatgagaa catgtcagaa tgtgaaacca gcagtgtgtg tagcagcagt gacactgggc
      781 tctttaccaa tgatgaaggg cgacaaggtg atgacgaaca gagtgattgg ttctatgaag
      841 gagaatgtgt cccaggattc actgtcccta atcttctgcc caagtgggct cctgatcatt
      901 gttctgaagt agaaagaatg gattctggat tggataaatt ttcagattcc acattccttt
      961 taccttctcg gccagctcaa agagggtacc atactcgctt gaatcgtcta cctggagctg
     1021 cagctcgatg cctcagaaag gggcgaagaa ggctggttgg gaaggagacc agcataaaca
     1081 ctttggggac tgagaggata agccatatca ttagtgaccc tcggcagaaa gaaaagaata
     1141 aagcgttggc ttctgatttt cctcacattt ctgcttgtgc acatgagttc aatcccctgt
     1201 ctccccttta ctccctggat gttcttgccg atgcttctca ccgaaggtgt tcaccagcac
     1261 actgctctgc cagacaggca aatgtacact ggggaccacc atgttcacgt gacatcaaga
     1321 ggaagcggaa accagtggcc acagcatctt tgtctagccc cagtgcagtt cacatggatg
     1381 cagtggagcc aaccacacca gcatcacaag cccccaaatc acccagctct gagtggttgg
     1441 tgaggacctc tgcagcagag aaagccacag acgcaactac tgctacattt tttaaaatgc
     1501 cacaagaaaa gagccctgga tacagctaga gagcaggact tcaccctcca ggagctgact
     1561 gggtgttgct gaagcaaatg ttggactttg tgttagatag tcttgcatat cttaatcgac
     1621 attcccagtc ctttcaccac cagaaccaac tcctctttca aacacagcag tggattcttt
     1681 ctctcagaag atcatgttgt gggaatcttt tttttaaata gtgaaatatt gaggcagcaa
     1741 ttttttacaa aaaggtcatc ctctgctcta tttgttacct tgttattgct gtctcaacat
     1801 ttactacagc tccatttaca gaactgttgc ttttttgcag ttgtctttgt tcttgaaaaa
     1861 ccagtaactg cttctgcata ccttttgtgt agagctttta atatcatttg aggaagttcc
     1921 aaatttgtag ccagttccaa acaaatttaa atattgagtt gagacctgta tggaattgtg
     1981 ttcgcaggag ataaggcttg cctttgagcc tactcttgat tcatgcagag tgccaataag
     2041 ataaatcaac caagttttgg ggcctcaaaa gagacaccag caactgggcc ttgagaactt
     2101 ccattttttt gcagattgtc tgcagaaact cagacagctc atcagcagca gcagctgtat
     2161 tgtattttac ctcatcttca gagtttatgt tctactgaaa gaggacgtgt gtatacacac
     2221 acacacacac acacacacac agattggtat aatggagaag atggtttagg tgtacagcaa
     2281 atttaaaata gtcagtggat tgtgtcttac tacttcatgt cccagtgtaa gcctttatgt
     2341 cctaagcagg actttattgt tagtattata ggctaataac ctgcagcaga aattcatact
     2401 ctattataat aatggcttct tggggccatg ctttggggaa gtaaaatgtc tttttgacat
     2461 gcctttatac ttggcgtgtt tatgatggct cagctgcatg tggagttata tatacagtcg
     2521 tgcctgaagt tggatgctac tttgtcaaaa tgagaaataa gtgatggcct ggagctgctg
     2581 gagagaagcc acgctttcta gaaaatatta tcaggagtgt ctgtcattca ttcaggggcc
     2641 tagctgacag aagggctctt ttttttatac caatgagtgc gtttactctg aaatacatag
     2701 aagctcttgg tgaagtgctc cctgctctgg tcacattgta gagggactcc cactcatgca
     2761 tctgcttatt ttctgtctta aataggtgct gaatggggca gcacctcctt cccccaaagt
     2821 gcgattgccc ctgtttccca tacgaagtgt aatgacgggt tgcttttaaa attatagtcc
     2881 ttatcaatgg aaactccaga tttctttatc aaagggaggt gggtgggcat gaatctagtt
     2941 ggaaaagggg acttgaagct aagtttacat ggcactttaa gactgagaac atatcaattg
     3001 ttcataatca ggaatatggt agagggagag caggtgtaga tgatgggacg ggaaagtgct
     3061 gaaaccagcc cagcagacct gtgagtcgcc tctggttctc acgcagcagt gtgtgtgtgc
     3121 tcacagggat gttccacccc tggttctcat gcagtagtgt gggagagtgc tgaagccggc
     3181 ccagcatgcc tcttagttgc ctctggttct catgcagcag tgtgtgtgct tacaggagtg
     3241 gagatgatgg gatgggagag tgctgaagct ggcccagcat gcctctgagt cacccctggc
     3301 tctcatgcag cagtgtgtgt gcttacaggg acttcccagg ctgcacttcc cttccctgtg
     3361 ggctgcaccc gtagaagtat agaaaatgta atgtctgttg aatataaaat cgtaccactg
     3421 aattgttcta gtgatgaggt tagattttgt tgtcatgtgc attgtcacca tagtgacccg
     3481 tggcatatat ttttaacata cttggttggg tttgagagaa atctgtggac gtaatttttt
     3541 gtttgtgtca agctctatga ctcatgcagt gattggtccc atgatcatgg cctattagtg
     3601 aaaacctcca aaggtcaggt ggccaaggtg ttcccacatt ttttctatat aacttgtttc
     3661 ctaatagtct gcctttctac ctatgattaa aaataatttt tatatacaac attatttaca
     3721 tttcaaacat ctctacgaag tcatgccatt ttaaggagat gaaaacagcc acagagttga
     3781 gtgacttgct ccaaatcaca taactaagcc aggactagaa tcccagactt tcagattttc
     3841 tctgccctgg gttataatct cttgtttttc agtgatagac ctgagtcagt ctgagatgct
     3901 tatttatgaa acagtatacc atgaatattt attatctttc ttgggcatgc ttttctacac
     3961 attttgaata ctttcaacag ggattaccca agaatgcaac atctacctgt aataaatggg
     4021 gagaaaatta gttgcctgag agaacagaat attaagcaca caaatacttt ccaacacagg
     4081 gttgtaaatt gtgctcctca ttttaaggtg ctgtacgtgc atgtttaagg aattattaat
     4141 cagtgtattc tgcttgcttt ctgtattaac cagttccaga ggatagcctt agaaatgagt
     4201 gtattttgaa tcttaaagtt tctttatatg cggcacagtg tataatgtcg taagttaaga
     4261 aaaatctgtt atctttcaaa gaagttacgt agtttcaaaa atgaggtttt gtaatcagtg
     4321 ttgaaaaaac tctgaactat gacttacttt gaggatgatc cttgagctca tgtatttgat
     4381 ctgctcaaaa gtaataacta aagctgagtt aaacagttgt tatttatttc agggttctga
     4441 tttttcccag ctggctacac aaatggcctg tctgaatcct agtttagtgt gttttccacg
     4501 atgggcagaa gtcagaacat tatctgcttc tgtgaggatc ataataaaaa gttagtttta
     4561 attacgagtt taaaggaatt ttagattttt ttcagatgca gtattttaaa ggaacaaaac
     4621 tcctgtgttg ccttttgttg ttgttgttgt tgttgttgtt tcctagagac aggttcttga
     4681 tctgtcactc aggttagagt gcagtgatgt gttcatagct cactgtaacc ttgaactcat
     4741 aagctcaagc catcctcctg cctcagcctc ctgagttgtg aggactatgg aagtgtgcca
     4801 ccatgcctgg ctaatttttt aagtttttgg agagatgggg tcttgctctg ttgcctatgc
     4861 tggtcttgaa ctcctaacct caagcaatct tcctgcctca gcctccccag gtgttgtaat
     4921 aataggtgcg agccaccatg cccagccttg tgttgcctct tggtaagaaa taataaaaag
     4981 aaattagtag cttgtttacc tggtaccaga tttggagggg gctgagtata atttttactg
     5041 agtggtatgt ggttggaaaa taggccacat ttagccttga attgtttaga aatcaaatgc
     5101 gattcagaat tgaagaggac attgctgggc tatgaaatag ggtactaaca aggctatttt
     5161 tgtagcaaaa tggccaaaag ctgaaataaa tcttcttagt ctgtgatgct tgtagcatcc
     5221 tttgttaagt aaagcacaac accctggaca agcgactagt tatgacttcc aaatagattg
     5281 ataatagcct tgcatgttgt agttagagac actgtagctg tatctgtata cctgtaatat
     5341 agcctgggaa gttctgttgc tgcagagtta tcattaaagt cacttggaat tgaaaaagat
     5401 acagagtgtt gagacaaagg aactaggctg gcacagtcat tgctgatgcg atgggttctc
     5461 cactttggct ccaggcgaag gctcctggtg gtgatgcatg attgatttca ggtctttgtt
     5521 tcattttggc ttcattactg tgattctgag ccacacaggt ttttccccct ggggagaaga
     5581 ctatgtaaaa atctcagcgt tagaagctgt gttcagtgcc ctatatgtct tgtgaaccta
     5641 tctgagctgg gctgagagca gagtggctta ctgtagcagc tgtggatgca gtctagttgg
     5701 aggcatggct tggaggacgt catggttcat gcgatggttg gagggatggt aaaagcagtt
     5761 agctcttgtc agctgcttcc ctctgctagt gcttgagctg ccaattttat ttgtcagtat
     5821 ttcctgatct cccactcctg ttgtgaaagg tcacagagtt actgtcactg gcaacaattt
     5881 cgccccttag aagaaaactg gtacagaggg aaagggtgag gaaaatggtg agttccatca
     5941 ctcagaacta aatgcaagtg gtagagagat gctttctcct gtgttaacgt ctccaaaaga
     6001 tgaacatcaa atgcccggaa acagcaacat caaaaagaag gaagatgaga agtattgttg
     6061 aagagtatgg acctacaggg tttttaacaa gtccagcaaa acaaactatg gccaaaagaa
     6121 gaaatttttc tgtcactgcg agtagacatc ataaatgctt ggtaaaattg ccagatttag
     6181 ggaataaaaa atttttaaag tacagtgttg aagaatgggg catgtcatga agacattcag
     6241 caaagaagca atcttggcaa ggtggagaag tgggaagcaa tggggagaga aagggagatg
     6301 cccagagcag gaattctcaa tgtgtggtcc ctaggccaac agcatcagca catcttgccc
     6361 tcaccagacc tactgaatcc gaaactccca gcgcaaggcc cagcagtctt caacaagccc
     6421 tccaggggtc tttggtgcat gctcaagttt gagaaccata ggctttgcca cggttaaaaa
     6481 gatgttttaa tggactggtc tcctcctaag ctctgaggtg ctctcatatt ccctccataa
     6541 gtaaagagat tttttttgta taattctttg cagaaactgt taatgtcttt atttctcata
     6601 tttttttttt cccctacaag ctcctgaaag atctttttga agaattgaca aaggatgcta
     6661 tcaagggcta tgtttaggtg gatggaaata accttttgaa aatggataaa gcctgggtgt
     6721 ggtgactcac gcccataatc ccaacacttt gggaggccag ggcgggagga ttgctttatt
     6781 gcaggagttg aagaccagcc tatgcaacac agtgagacct tgtctctaca aaaaatttta
     6841 aaaattagct ggctgtggtg gtgcatgcct gtggtcccag ctacttggga ggcagaggca
     6901 ggaggatcac tcaagcccag gaggttgagg gtgcagtgag ccatgatctg gccactgcac
     6961 tccagcctgg gtgacagagc aagaccctgt atcaaaaaat agataataaa ataaaaattg
     7021 ataaaaatag atcaatgaat tgttagtcta cgaatgatag tcatttttca caattggcag
     7081 taaaaatagg atttgtgtaa ggtatgagtt taccatattt gttcattaga tcttagtttc
     7141 aagggaaagt atcatgtatt ttccagcatg ataatgatga atcatttaaa gtacggctca
     7201 taaaaatgaa aaaaaaaatt ggaagaaaaa aacaccttgg gtacatagat gtgtaataaa
     7261 tacctgttga gttattggta atctcttgct aggactgaat ctcagtactt cagagcatgt
     7321 aaaaatcaat tttctgtgat cccacttaat cacaccgtgt tttctttttt tagatttcag
     7381 ctagcaattt tgcaggggtt ggagaccaat agcgatgtca tgctttttgg ttgttgttat
     7441 tgtctgactc gtggattcag catttcagaa tatggtactc taatcttaag gctttgaaaa
     7501 gaaaccatgg ccattttttc ttcatatttt acctttatta attgggctgg gtcctaactg
     7561 gttgccagag cccagaaatc caagttctgt cttttcaggg aatatgcata gctaaagagt
     7621 tcattgtgtt tgcaaaggtg tactaggagt tctcatttcc tcagatgctc atgtctgtag
     7681 gctgttaagc tctcatttca atttttgcag tcttttaaaa caccacactt cttttccatc
     7741 ttgaagacca gttaaaacta cctctggcca aaaatgttag tgttactaga tattatcaag
     7801 gtgtgagact aaaaagttag aaggctttaa gatgtaaatt atataagtta atgttttctt
     7861 tccctaaaag ttctgaccct tgctgacccc tcaatcaaat gtttttaatt gaaaggggaa
     7921 agaaaatatc agagaactta aagatggcct tcgtgacttt gactcaaaat caatgcattt
     7981 cattatgtat gggtcctaca ccttgcttcc tcaagtggcc atgaaaaaaa atctcacgac
     8041 catgcaaact gatgccaccc caaagtcatg gtaacgattt gaattgctct cagtattgat
     8101 gtcaaactcc ctcctgttgt cagcagctta ttgcaaactg gccattctaa acccttttac
     8161 ccccaccttc tctcaatctt agcagttaat ctcagccctc ccccaccaca taacagcctc
     8221 gggcagaact tcccacttag acacccacac acacacacgc ttccttacct tcttgccagt
     8281 gcctgtcctg cccaagacga accccttttc ctgtgcccta ggacctctcc cttgataaat
     8341 gacttgatct agctacagcc tcacactcct ggcacataca gctttgcatt taaacatgtt
     8401 cagatactcc ttccttcaaa caaaagacct ttcctcaacc ctttgaaagc ctgagtacca
     8461 ctaaggtata ctgcccttat ctgcactctg tccattctgc agtctaccga ggcagtggtt
     8521 tttaaccctg gctgcatgtt agggtcacct gggaagtttt aaaaagtcct aattcctgga
     8581 ctggaccaca gaccagttaa atcagcatgg ggaggtgggg atgggtttca gtctttaaaa
     8641 agaaatgtag ctgaggctga gaaccaccac tctaaaacct ggctgctacc cttgctacca
     8701 ttaaaactgt tcttgctgga ttcacccacc agtgacttct actattaaaa tttagcccat
     8761 aggttgattt ttatgacact gatgctatat aaccacttcc ttctttggaa tgctcccttt
     8821 cctgacccta ctttcctgat ttttctgcca cttctttgct ctttctcagt ttctgtggag
     8881 ttgtttggta ggtcagtcta gcacagactg gatgccggtc tctgccgcca cctccgttat
     8941 ttcagtgaac acctgtatgc cagtgagttc ctttgccata ccaccttaat gcaccaactt
     9001 aaaagcacag attagagtgg agcattcaca tttattactg caggcttcta ggaaagcata
     9061 ttaaaggtct ctggtccttc tctcacctcc cttgttcctc ctccaagccc agtgaggtag
     9121 gaggaattgc taattagatt agtgagattc taaggtgggt cactcctgtt tacttatgag
     9181 ttgctattta tgaaaagatg gcctggactg tgttccctct tctgctttct cctcttccgg
     9241 gtcttggact ggtaaggggg cctgtgccca aaaggggctc ctccacctaa tgctgtcttt
     9301 aatctgtggc tttctgctgc tggttaattt tttaatttgg cttcctcaag cctttttggc
     9361 cttgaacttc atgttgattt ttatcaaaga actttttatt ggggcatcag cactagccct
     9421 atgaatacag tgaaacttgg ggttccactt tcatcagatg tgaccctgtg tgttcctgat
     9481 gtctttgaat cactagtttc tgattcaaaa tatggggtag gtggatctga ttagtagtca
     9541 tatgcctgtg tcctggctag gaagtcagaa tgaggttatc tggaaagttg agcttcctca
     9601 cacatgggaa ggtacttcag atgctggaca gccaataaga ataacaaagg tccaccagaa
     9661 ccattgcccc agtcactgat tgaacaaaca tttactgaac actgatgaag cgaagtcctc
     9721 ctcagggacc tcttagggaa gagggtaact gccctaaagc aggatactcc tgggctcctt
     9781 agatatacta tccttgaaac tattaggccc ctgtccagag tacctaataa taataatggc
     9841 aaatatgtat ttggtggtct gccatttgga agcaacatct cacttattca acaactctaa
     9901 aggtaggtac ttttatctcc attttaaaac aatgaaatac acttacagtt acagacaaac
     9961 ttgctcgagt cacatatcta ttaagtgtca gtcaagattc agattcaagt ctgatgttaa
    10021 agagtgtctg ttcccaatca atacctctgc tgcctctttt tacaaactga actgttggag
    10081 ggcatgtaca tatgcataag ctgtgggcca ctgggccatg ggccagtgtc tgatgagacc
    10141 tctttattga cttgtttgtc ctggtgggct gtttctctac caggcaactg tgaatgggct
    10201 catcccttct ctgtgcgtac atgattgaaa ggagatagcc ggtttctgtg acatcctctt
    10261 ataacaacct agttttgttc ttgagagtga ccagagcaag agaaaagtca atgaaatttt
    10321 gcagatcttg caaacctgtg gcaataagaa ggtattatcc tttctgtacc aaggcacaac
    10381 tgattcctaa gtgaggggga tatgtgttct gagatgttaa tgttagtgat agactgtttt
    10441 caacaccttg gtaaacattt cttttgactg ttagcaaaag ctgccttaac agtcttggct
    10501 tttagaaatg ccccttcatt cattagatgt gtatggaaca catcttatgc caagcactct
    10561 gctaggagct gggtatacag agaagaaagg cattcctgct ctcatgatgt tcatggtctt
    10621 ctgcggaaga gaccagaaaa aaagtattac aatgtagaat gaaataagaa tgacagggta
    10681 ttttggcagc aaggaggagg gcactttaac tcaaactggg cagtggaaga agtaaaaaaa
    10741 aacattgaaa gaaatcctga aggataagca ggagttaaga agagtggatg aagccctcca
    10801 agggtaaaag catggtttat tcagagcact gcaagtgttt tagtatggcc cacatgtaaa
    10861 gcttacagag gaacaaagag agaaaggcaa gagccaggaa gtgaagggtc ctgtgtatac
    10921 tggcttactt gttgagttgg agaactattg ccgtattcct ctgctaagct cagggtgcat
    10981 tcgtggaaac cctactgcaa ctggcccatt gtgcatacaa agctggaact gagatgtgaa
    11041 cagatttgca ttgccttgat caccttccgt gggaaatata gctaggccca cttattggta
    11101 ggagctactg acatgttaaa actaggttaa actgaattgg aagtaatggt gtatttggaa
    11161 tcatggctga ctgattccat tacatgttct agcatgatac cagtctgagg ttattcccct
    11221 tgaaccaccg acttagtaga gtttaatgca caatgtgatg gtcttagttc cttgtactgt
    11281 tcttcagtgt caaagttgtt caactaccag ttaagttttt tgggctttgt ttctcagtag
    11341 tgacaataaa tttgtgttga tctatttaca ccttttggac tgaacacctt agcaatcatt
    11401 gatattttaa gcctacagga agtgcccatg ggataaaacc aatctgctgg ctcacactaa
    11461 gttctgatcc catgattttg gtctcattaa taccgtgcta taaataaagt tagctaaatc
    11521 ttttgaaact gcataaaagt gaaataatta tgagttttgg gccaacattt ttcctgaaca
    11581 gcttctgact gaccagcatt ttaaattagg cgatgcagtc tagcttttgt acatagaaat
    11641 aagaaagtga cttatgttcc attattaaaa tagtataggg aggacaggta aattactaat
    11701 ttttcattgc tcatagtaga gaattaaggt atattgacta gtgaaataga ggattatggg
    11761 gatcatatga aaatatgatt aaagagatta tcactagaag aaaaattcag actgctaatt
    11821 atgagaaaaa acatgtatgc acaaccaaac aaatcacaaa aatgaaagat gtctaaaacc
    11881 atagaatagg aacaaatgta cctgtcatat taataaaagt aaacttatct gtagataaaa
    11941 ggcaaaaatg tcagcaaaca ctaatttcat gttataagat tcagaaaggt tgagcaaaag
    12001 taaaccaagc aaacacaaac aagaaaatga gttgtagtct gcatatcagg caaggttgaa
    12061 cttagggaaa aggaaccgga aaaaaaaaaa ccaaaaaaaa ccacgacata atgctaaagg
    12121 gtgtgactca cgagataatg tttctagata tctgtgtacc aaataatgga aaaccattta
    12181 tgtattggaa accataggag acacaggaag aaacaaatac aatgttagtt ggatatttta
    12241 attcaattct gtcaattcat gacagatcaa gtggataaaa aactaggaca tgggatgatt
    12301 taaataagat acagaagatc tagttgatgc atattagact ttaccctaaa agtggtaact
    12361 acacttcaaa gtatccatga aacatttccc catttgactg tgtattagag cgtacagaaa
    12421 acataagttt cagaacggaa aaaaggaaca acagatggca tttgctgata aaaatgcaat
    12481 aaacttagaa tttgaggata ggtggtcaga aaaaaaaatg caataaatta aagccagaaa
    12541 acactgctca tctgcaatcc aaaatgtttt taagctcttc aactattctt gggttgatta
    12601 ggaaatgcaa agtattaaaa aaacatttca tatctaaaat ataaacttgt tcctctgaga
    12661 tacaaataaa acagtgctca gaggaaaatt cattgcccta aaatttatgt attaaaaaat
    12721 aagataaatg tcatataact caaaatatta ggaaaaggaa tcttttaaag gcaggctaaa
    12781 agaatcaaga aaaattaatt agaaaaatga ggaaacaaag ctaattttta aaatatgtag
    12841 taaaatatgt aacattttag ctaacattac aagagaagac aaacacaaaa taagaattac
    12901 caagtattga ataggtaaga gtcataaaat attctttgct caactgtatg caaacaattt
    12961 aaaaacttgg attaaatgga taattttcca ggaaggtata gtttgccaaa aaatgacatc
    13021 aaaagaaatc taatataaca attgtcatag aagaaatgaa gtaagtattt caattagcat
    13081 gacagactaa atacttttaa agacccaatg aaaacaaaga aatgcatttg gagaattaac
    13141 agaaactttt tgtaacacca attttttatt ttacatttta aagcatggaa tggaatttat
    13201 tgtaaagacg tgtattttat agaatccaag caaaagctca ccagccagag ataaagtgag
    13261 gccagctcag ggaatgtgag cagtggcgat ttattccctc tggtgttcca tgttagcctg
    13321 acacagagcc ccctcttcac attctcaggg gctcttgatc caaaaccttt tttaaaaaaa
    13381 ataattttag acttaacaga aaatctgcaa aaatagattt cctgtgtgcc cttctctcag
    13441 cttcttctaa tgttaactta cataccaatg gtacaattat tgaaactagg aaattaacat
    13501 tggcacaatc ctattaacta catactttat ttgaattgta gctgttttcc cagtaatgtt
    13561 gtttttctgg ttcggtattc aatccaggat ccatatgtac ttgggtcttt ctgggttttc
    13621 tgttccactg gtctacttgt gcatggtacc acactgtttt aattatagag actttatagt
    13681 atgttttaac aactggcaag gctagtcccc cttataattt ttcctattgt gcttctggct
    13741 attcatacat gtttgttttt ccatgtgaac tttagtatca acttgtctaa attcattttt
    13801 taaggtacat tggtatttta ttgatattat atgatattaa ctgatttaga gagaactaac
    13861 atctttaaaa tgtggtgtca tcctatccaa gaataggaga tgtatttcca tttattcaag
    13921 tctattttgt gccttttagc agtgttttaa aattatcctt gtgtaggttt tgtgcatttc
    13981 ttgctaagct tatccctaag tatttaattt atttgctagt a
//
