LOCUS       NM_018559               3442 bp    mRNA    linear   PRI 06-JUN-2022
DEFINITION  Homo sapiens GPALPP motifs containing 1 (GPALPP1), transcript
            variant 2, mRNA.
ACCESSION   NM_018559
VERSION     NM_018559.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC333111.1, BC039586.1 and AL359706.18.
            
            On Aug 31, 2019 this sequence version replaced NM_018559.4.
            
            Transcript Variant: This variant (2) differs in the 3' UTR compared
            to variant 1. Variants 1 and 2 both encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038193.1831741.1, BC039586.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000379151.9/ ENSP00000368447.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-14                DC333111.1         9-22
            15-1407             BC039586.1         1-1393
            1408-3442           AL359706.18        52210-54244
FEATURES             Location/Qualifiers
     source          1..3442
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="13"
                     /map="13q14.12"
     gene            1..3442
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="GPALPP motifs containing 1"
                     /db_xref="GeneID:55425"
                     /db_xref="HGNC:HGNC:20298"
     exon            1..205
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1140
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="isoform a is encoded by transcript variant 2;
                     lipopolysaccharide specific response-7 protein;
                     lipopolysaccharide-specific response protein 7; GPALPP
                     motifs-containing protein 1"
                     /codon_start=1
                     /product="GPALPP motifs-containing protein 1 isoform a"
                     /protein_id="NP_061029.2"
                     /db_xref="CCDS:CCDS9394.1"
                     /db_xref="GeneID:55425"
                     /db_xref="HGNC:HGNC:20298"
                     /translation="MARDLIGPALPPGFKARGTAEDEERDPSPVAGPALPPNYKSSSS
                     DSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQ
                     DDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNV
                     TTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSG
                     DRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESL
                     MDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHG
                     KGNMFL"
     exon            206..338
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            339..440
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            441..525
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            526..657
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            658..822
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            823..921
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     exon            922..3442
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1377..1382
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="hexamer: AATAAA"
     polyA_site      1407
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="major polyA site"
     regulatory      3404..3409
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="hexamer: ATTAAA"
     regulatory      3419..3424
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
                     /note="hexamer: AATAAA"
     polyA_site      3424
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
     polyA_site      3442
                     /gene="GPALPP1"
                     /gene_synonym="AD029; bA245H20.2; KIAA1704; LSR7"
ORIGIN      
        1 gtcatttctc ggcgccggga aacctgccat tcttcgctgc tgatcgcggg attctttttg
       61 gatagggttg acgttcgtgg atagactcat atctgtgacc agtgtccgcc accgcggatg
      121 gcaagagacc tgatcggacc ggccctgccg cccggcttca aggcccgcgg aacagcggag
      181 gacgaagagc gggacccgag ccctgttgca ggaccagctc tgccccctaa ttataaaagc
      241 agtagttcag attcatcaga cagcgatgaa gacagtagtt ctttgtacga agaaggaaat
      301 caagaatctg aagaagatga cagtggtcca actgcaagaa aacagaggaa aaatcaggat
      361 gatgacgatg atgatgatga tgggtttttt ggaccagccc ttcctcctgg atttaaaaag
      421 caggatgatt ctcctccaag gcccataata ggtcctgcat tgccacctgg tttcattaaa
      481 tctacacaga aaagtgacaa gggcagagat gatccaggac aacaggaaac agacagcagt
      541 gaagatgagg atattattgg accaatgcct gcaaaaggac cagttaacta taatgtaacg
      601 acagagtttg aaaaaagggc ccagagaatg aaagaaaaac tgaccaaagg agatgatgat
      661 tcatctaaac ccattgtaag agagtcatgg atgactgaac ttcctccaga aatgaaagac
      721 tttggtcttg ggccaaggac ttttaagaga agagctgatg acacatctgg agatcgatca
      781 atctggacag atactccagc tgatagggaa aggaaagcta aggaaacaca agaagcaagg
      841 aagtcatcca gtaagaaaga tgaagaacat atattatcag gaagagataa gagactggct
      901 gagcaggtat cttcatacaa tgaatcaaaa agatcagaat ctcttatgga catacatcat
      961 aaaaagttaa agagtaaggc tgctgaagac aaaaataagc ctcaagagag aataccattt
     1021 gaccgtgata aagatctcaa ggttaatcgg tttgatgaag ctcagaaaaa agccctaata
     1081 aaaaaatcta gagaactaaa caccagattt tcacacggca aaggcaatat gtttttataa
     1141 gtaagtatat ttcagtgagg tatattttaa tactgatcaa tgtgaacttt tctaaatact
     1201 ctattgtctt taataattgt gctgaaatct atttcctttt ataatagatt aaaaatttta
     1261 tatttttata agtaaacagt gatttttgaa aagtcagcct tgtgggatga aaaatatgtc
     1321 ttactggaaa aatccctcat aataacctaa tagggcattg ctattaaaaa tgctaaaata
     1381 aaaattcagc ttatgagaaa tggcaaagga aggtgtggtt tgatacttga gtaaatatgc
     1441 atgctttatt aaagatgaag aaaggcttgc tggttgtttg tatgttaaac aaaatcccaa
     1501 ctaggaaatg tttgttgctt agaaaggtcc cctataagtt aaggttcaaa actattccaa
     1561 tattcatcca tagcccaatc tgacaagggt tcagaatggt gattaagaaa ttacataaag
     1621 ctgggtgcag tggctcacgc ctgtaatccc aacactttgg gaggccaatg tgagaggatc
     1681 gcttgagccc agtagtttga gaccagcctg cttaagatgg tgagaccccg tatctacaaa
     1741 aaactaacca ggtgcagtgg agcacaccta tagtcccagc tactcagcag gctgaggtgg
     1801 gaggatccct tgagcccagg aattcaaggc agcagtgagc tgtgattgtg ccattgcact
     1861 ccagtctggg caacaaagtg agacctcgtc tctttagaaa aaaaaaaaga ggccagtggc
     1921 tcacacctgt aatcccagca ctttgggagg gtgaggcggg tggatcacct gaggtcagga
     1981 gttcgagacc agcctgaaca acatggtgaa accccatctc tattaaaaat atatatatat
     2041 aaaaattagc caggtgtggt ggcacgtgcc tgtaatctca gctacttggg agcctgaggc
     2101 aggagaattg cttgaacccg ggaggtggag gttacagtga gccgagatcg tgccactgca
     2161 ctctagccta ggtgacaaga tcgagagact ctgtctcaaa aaagaaagaa aaagagaaga
     2221 aaagaaatta cataaaagct gaggttgctt cttaatatct ttatgatttt taattgtatt
     2281 aaacctatat caatattcaa atgtgatttt tgaggaaaat atgttaaatt tagaaatatt
     2341 ttccaactta ctgagttttc ttattcttac ctcaggggga tttccctgtg caatgaagaa
     2401 aagttgaaga atactctttg tccatcttta tttctttgtt tttggcttct taagattaga
     2461 gattacttta atcttaaaaa acatacaaat ttaccttgtt ctgtatgtcc ttttaaggtc
     2521 atgtggaaac ataaaacgaa tgttttttat gtagaacaga atattctatg tgcctttagc
     2581 ttctgtggaa gtatggggaa ttatgggctt ttcttcaaat aattatttta agaggcttcc
     2641 attccccctg atttttgtgg tgtctcacaa gtaccctcta aggtctggtc aggactgacc
     2701 accaaatctc taccacagcc tggacctcct tgtgaaatat acctaacctg ccctagagtc
     2761 agtgtgtcaa gtccttactg taaatccatg actttgaaat ttgttgtttt ttccctttaa
     2821 actgcagcca gtgaatacaa atttacttga aaatagaggg tatggggttt tgcctgtttt
     2881 gtaatcagtt tgcttgtttt agcactcagg gctttttatt tgttatttaa ttttttaatt
     2941 gtttttaagt cagaaagatc tctgggttat ctcatgtgct aaggaaaaac tattttgctt
     3001 tttccaactt taatagttag tatttctagg ggaggcaatc aagataagat atgccattaa
     3061 ctgttagcat tgtgaaatct gtaagactca atctctgatc tcaaccaaag ctttctgagt
     3121 cctggaactt tgctttggga caactttact ttacccattt atatgctgta cttaacagtt
     3181 tgtagctaat ttatggggtc atatcttttt tttagctaat ttacgggggt catatcagtc
     3241 atgaatagcc ttttttaaaa atttaataat ccctgaatac aaaaatggaa atggaaaatt
     3301 tataatcata acccccctaa ttgggagtat tataagtttg taatgcttta agcactgcct
     3361 cttaagatga taaatttata agatgagaaa ttctatttaa actattaaac tattgttaaa
     3421 taaatgccaa ttctataagt ta
//
