LOCUS       NM_001395373            5186 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens golgin A8 family member S (GOLGA8S), transcript
            variant 1, mRNA.
ACCESSION   NM_001395373
VERSION     NM_001395373.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5186)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC100756.5.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000562295.3/ ENSP00000455298.2
            RefSeq Select criteria    :: based on manual assertion,
                                         conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC100756.5         84724-84869         c
            147-266             AC100756.5         82907-83026         c
            267-326             AC100756.5         82262-82321         c
            327-407             AC100756.5         81998-82078         c
            408-446             AC100756.5         81107-81145         c
            447-494             AC100756.5         80786-80833         c
            495-579             AC100756.5         80613-80697         c
            580-689             AC100756.5         80408-80517         c
            690-779             AC100756.5         79299-79388         c
            780-887             AC100756.5         79085-79192         c
            888-975             AC100756.5         78802-78889         c
            976-1211            AC100756.5         78161-78396         c
            1212-1280           AC100756.5         77825-77893         c
            1281-1356           AC100756.5         76377-76452         c
            1357-1448           AC100756.5         75848-75939         c
            1449-1549           AC100756.5         75174-75274         c
            1550-1647           AC100756.5         74994-75091         c
            1648-1803           AC100756.5         74743-74898         c
            1804-5186           AC100756.5         71276-74658         c
FEATURES             Location/Qualifiers
     source          1..5186
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q11.2"
     gene            1..5186
                     /gene="GOLGA8S"
                     /note="golgin A8 family member S"
                     /db_xref="GeneID:653061"
                     /db_xref="HGNC:HGNC:44409"
     exon            1..146
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1979
                     /gene="GOLGA8S"
                     /note="isoform 1 is encoded by transcript variant 1;
                     golgin subfamily A member 8S"
                     /codon_start=1
                     /product="golgin subfamily A member 8S isoform 1"
                     /protein_id="NP_001382302.1"
                     /db_xref="CCDS:CCDS91964.1"
                     /db_xref="GeneID:653061"
                     /db_xref="HGNC:HGNC:44409"
                     /translation="MWPQARLPPHPAMAEETRQSKLAAAKRKLKEYWQRNSPGVPAGA
                     KRNRKTNGSIHETATSGGCHSPGDSATGIHGESPTSSATLKDLESPCQELAVVPDSRS
                     VKVSQLKNTIKSLKQQKKQVVHQLEEEKKANNEKQKAERELEVQIQRLNIQKGKLNTD
                     LYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALSAVTATQKKKAERQFSSRSKAR
                     TEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEYAEHLKGERARWQQRMRKMSQEV
                     CSLKKEKKHDKYRVETLERSLSKLKNQMAEPLPPEPPAVPSEAELQHLRKELERVAGA
                     LQAQVEYNQRISLLNEGQKERLREQQERLPEQEERLQQLAEPQNSFKELNNENKSVLQ
                     LEQQVKELQEKLGKERLEAASQQKQQLTAQLSLMALPGEGDGGGHLDSEGEEAPRPIP
                     SIPQDLESREAMSSFMDHLEEKADLSELVKKQELRFIQYWQERCHQKIHHLLSEPGGR
                     AKDAALGGGHHQAGAQGGDEDEAAGAAADGIAAYSNYNNGHRKFLAAAHNPADEPGPG
                     APAPQELGAADKHGDLCEVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGNNCC
                     VPFFCWAWLPRRRR"
     exon            147..266
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            267..326
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            327..407
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            408..446
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            447..494
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            495..579
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            580..689
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            690..779
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            780..887
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            888..975
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1211
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1280
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..1356
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1448
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1549
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1647
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1648..1803
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..5186
                     /gene="GOLGA8S"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5143..5148
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA8S"
                     /note="hexamer: AATAAA"
     regulatory      5151..5156
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA8S"
                     /note="hexamer: ATTAAA"
     polyA_site      5166
                     /gene="GOLGA8S"
                     /note="major polyA site"
     polyA_site      5186
                     /gene="GOLGA8S"
                     /note="major polyA site"
ORIGIN      
        1 agtcgcacag ctacctggta ggtgactgga ggtgttgatc agtgcttggt gggattttgc
       61 tgatgtggcc ccaagcccgc ctccctcccc accctgcgat ggcagaagaa actcgacaaa
      121 gtaaattggc agcagccaag agaaagttaa aagaatattg gcagagaaac agccctggtg
      181 ttccagcagg agccaagagg aacaggaaaa caaatggcag catccatgag acagccactt
      241 ctggtggttg ccactcacct ggagattcag caacaggtat ccacggggag agccctacat
      301 catctgctac cctgaaggat ctggagagcc cgtgccaaga actagcagta gtcccagact
      361 cgaggtccgt aaaagtcagt caactgaaga acaccatcaa atctttgaaa caacagaaga
      421 aacaagtggt acatcagctg gaagaagaaa agaaagcaaa caacgagaaa cagaaagccg
      481 aaagggagct agaggttcaa atccagagat tgaacataca gaaagggaaa ctaaatacgg
      541 acctgtacca cacgaaacgt tctctcagat actttgaaga agagtccaag gatctggccg
      601 tccgtctgca acattcattg cagcgtaaag gagagttaga gcgggctctc tctgctgtca
      661 ccgccacaca gaagaagaag gcggagaggc agttctccag ccgcagtaaa gcacgtacgg
      721 agtggaagtt agagcagtcc atgcgggagc aggcactgct gaaagcgcag ctgacacagt
      781 tgaaggagtc acttaaagaa gtccagctag agagggatga atatgctgaa catctaaaag
      841 gagagagggc ccggtggcag cagaggatga gaaaaatgtc gcaggaggtt tgctcgttga
      901 agaaggagaa gaagcatgat aaatatcggg tagagacgct ggagaggagc ttgtccaaac
      961 tcaaaaacca gatggctgaa cctctgcccc cggagccccc agcagtgccc tctgaggcgg
     1021 agctgcagca cctgaggaag gaactagaga gagtggcagg agcgctccag gcccaggtgg
     1081 agtacaatca gcgcataagt ctcctgaatg aggggcaaaa ggagaggctt cgggagcagc
     1141 aggagaggct tccagagcag gaggagaggc ttcagcagct ggccgagcca cagaacagct
     1201 tcaaggagct gaacaatgag aacaagagcg tactacagtt ggagcagcaa gtaaaggagc
     1261 tgcaggagaa gctaggcaag gagcgtctgg aagctgccag ccagcagaaa cagcagctaa
     1321 cggcccagtt gagcctcatg gctctccctg gggaaggaga tggaggagga catctggaca
     1381 gtgaggggga ggaggcacct cggcccattc ctagcatccc acaggacctg gagagcaggg
     1441 aggccatgag cagctttatg gaccacctgg aggagaaggc agacctgagt gagctggtga
     1501 agaaacaaga acttcgcttc attcaatact ggcaagagag atgccatcag aaaatccatc
     1561 accttttatc agaaccaggg ggccgtgcca aagatgcggc actgggagga ggacaccatc
     1621 aggctggagc tcagggagga gatgaagatg aagctgctgg agctgcagca gatggtattg
     1681 cggcttacag caactacaac aatgggcaca gaaaattcct ggccgctgcc cacaaccctg
     1741 ctgatgagcc cggtccagga gccccagccc cccaggagct tggggctgca gacaagcatg
     1801 gtgatctttg tgaggtgagc ctcacctcct ctgcccaagg agaggccagg gaggatcctc
     1861 tccttgacaa gcctactgca cagccgatcg tgcaggacca ccaggagcac ccaggcttgg
     1921 gcaacaactg ctgtgtgcca ttcttttgct gggcttggct gccaagaaga aggagataaa
     1981 catcaccatc atcaaagagc tgctcaagaa atttttaaat aagaaaccaa gttatggggt
     2041 taatctccta cacaattcat ttacttcctt tgaatgttag agtcactcat gattatttgt
     2101 gtttctaatt tatagtttta agtttatttg taaaaagtta aaagagagtg ggtgtctgtg
     2161 gctctcactg atgttcactc tggcatcctt tagcattttt cttttttaat ttcataattg
     2221 taggtcatta gcatgcatat cgagtttgcc cttacgtggt gggggttcaa acacacaaag
     2281 acccactctt tgcccaaaac tgttctcgct ggtttggaat aggctgccat gcttttttaa
     2341 tgttattgca gcatgtatat tcactacaga attcagacaa aatttgccta tgttctgctg
     2401 ttgtttgatc taatcttaat cacagtgagc tcttcgttag ctcaatatgt agtttgcccc
     2461 caagcgtgca ctgtttatta ctttgtaata tgccactatg agtactgaca tttagagttg
     2521 tttaaaggcc aagaactgga aacagccttt cctccatttt ctgtgtattg gtgatgggag
     2581 tgaaaccttt tgagggagct ttttaaatct cacagaagag gaaagtggcc tcctctggca
     2641 ggtatgtcca ggatagagtg tgtttcatct gttccggtgc caggaattag cagtgtatta
     2701 tggtggttcc cttaggattt gtatgtgctc tgggctcatg aagatactgc atcatgagct
     2761 gcagcagttg tactcttttt caatgaccta aaaagggctt atttctgagg aatgaaaggt
     2821 tcccatcgtt gactgtggat gtggaaaacc tttcctagct tagagcattt gtatctacaa
     2881 tacattttaa actcagagtt catgttacct gttttaatca catgactaca tgtcccagta
     2941 cacaaaaggg cactggttgg cattcttctt aatgtattta gtaaagatca taagaaatcc
     3001 tttacgagtt caaatgtccc tggaacaggc atacaggctc tagtcaagaa tgaattagag
     3061 tgaaggaaag ctgtgtgaca cctggcattc ctctctgttc acggagattc tttgaggctt
     3121 gaagattgat tttaccatct agacctcttt ggctaatacc tattcttcaa ccaccttggt
     3181 tactctgaca taggaattta cttctttttc cttgaatgga aaacacttta aaaaataata
     3241 gaaacattat tataaactaa tatatgtgag atacttagtt gaaacaaaag ggagttttag
     3301 tagacggtat tatactatct ttgaaaatca aggagaagtt tatgaaactt aaaatgtgta
     3361 caaactgcag tgcaatctac tgttcgtgaa tgtcaatgta ttatcaggaa acgtgcctat
     3421 acaatcacag agttatattt tctcacagac ttctttacaa agtgaaatat gtttttgtat
     3481 ctctgggttt ctgttcggga catattttgt gcaatattta tgtgattgtg cctatgcatg
     3541 atgaatgaat gcatttcagt tatgtattgc ctaaatcgta acttgatgat gcttgggaaa
     3601 gactcaacag ttaaaacttc atgaagttct aatgtctgtg ttccaaaaca catcacattg
     3661 ttaggatgca gggagatagg tgtgtgtgct ccctgcggtg gggatttcta gttactagat
     3721 catctccatt tttagcattt ggcatcctca tgatacttct ataaatatga cattaacagg
     3781 agagcaacaa tacgatttta ccgatggaat aacagatttg ctggcattca ctgaaagagt
     3841 gcaaatattc ggtccttgtg acttcaactg actcttccaa attttatgaa tgtatcaatg
     3901 tattagataa acccagtttc agaatgataa agaaaaaatg ttagaccaaa taatgcggct
     3961 aattaacagt ggtacgattt ctagcccgtg ggtttaaaat gcacttaaag tcctgttctc
     4021 gccttttatt ttctgaactt gccgcttttg cattctttga gttcagttta aagacggtta
     4081 ctttaagagc attttaaacc ctcgggctag aaatcggacc actgttaatc agccacatta
     4141 tttggtctaa cgttttttct tttatcattc tgaaactggg tttatctaat acattgataa
     4201 attatttcaa aggtactttt atcgttgaaa tcacttcact tttaccctga taaatatcag
     4261 tgactaggaa tgaccttcgg atagcgttta gcatctgtaa ccaatctgac aataatgtgt
     4321 tcatgaggtg cctatggatt aaatcacaca ctggcatatt taagctgaag gtcagtctgg
     4381 aaaataaatt tactatattg actgaaatac cactctttgt gtaggtattt gtcatatatt
     4441 taagaaaaag ctaaaaggaa tggaaattgt atgacaataa cttaagtctt tctccaaagt
     4501 gcatgcagtc ttttgcgata cctcattcag ccgagtattt gtgctcttcc tcattcggta
     4561 taaggcagct ttcagtttgc ttagaaggca acattggaat gttagagttc atcagaaaca
     4621 tagaatttta aaatgtgagt tccactgaat acattttaat ttctgtagga agaatcaaaa
     4681 cacctattta aagatggcaa tatataataa tcattttaaa agtatttgat taaacctgat
     4741 aattttccag aaatgaaaaa aaaatcagct ctaaaacgaa agctgatttt agaaaatttg
     4801 aaaatgtaaa tcagccctat ccataatata gtttctctaa aactttatct tagagtcatt
     4861 ttaaaataat ataactatta aaaatgtaac tgctatctta atgttctgaa ataagttaaa
     4921 acattttaaa atatgaatac tatagtataa aagaaagaaa cagtgggaag gaaaagcaga
     4981 gaaagaaatg ccaattccag tccaaagctt tatttgccaa gttttgttag aatgaatttt
     5041 accagtttgt gaattcttgt aaacagaatg tgtaatggaa atactgaaag atttttccct
     5101 agagtggcct tattgactgc tggtgtgatg ccactgtaat gtaataaatc attaaattgt
     5161 ttctaagtgt tgtttttgcc ttaaaa
//
