LOCUS       NM_001282490            5188 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens golgin A8 family member H (GOLGA8H), mRNA.
ACCESSION   NM_001282490 XM_003959940 XM_005276468
VERSION     NM_001282490.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Speed,D., Hoggart,C., Petrovski,S., Tachmazidou,I., Coffey,A.,
            Jorgensen,A., Eleftherohorinou,H., De Iorio,M., Todaro,M., De,T.,
            Smith,D., Smith,P.E., Jackson,M., Cooper,P., Kellett,M., Howell,S.,
            Newton,M., Yerra,R., Tan,M., French,C., Reuber,M., Sills,G.E.,
            Chadwick,D., Pirmohamed,M., Bentley,D., Scheffer,I., Berkovic,S.,
            Balding,D., Palotie,A., Marson,A., O'Brien,T.J. and Johnson,M.R.
  TITLE     A genome-wide association study and biological pathway analysis of
            epilepsy prognosis in a prospective cohort of newly treated
            epilepsy
  JOURNAL   Hum Mol Genet 23 (1), 247-258 (2014)
   PUBMED   23962720
REFERENCE   2  (bases 1 to 5188)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
COMMENT     INFERRED REFSEQ: This record is predicted by genome sequence
            analysis and is not yet supported by experimental evidence. The
            reference sequence was derived from AC026150.7 and AC091057.6.
            
            On Nov 20, 2020 this sequence version replaced NM_001282490.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on paralogous alignments.
            
            CCDS Note: The exon combination of this CCDS representation is
            inferred. It is supported by paralogous golgin A8 family
            alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000566740.2/ ENSP00000456894.1
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC026150.7         104375-104520
            147-266             AC026150.7         106190-106309
            267-326             AC026150.7         107202-107261
            327-407             AC026150.7         107443-107523
            408-446             AC026150.7         108377-108415
            447-494             AC026150.7         108678-108725
            495-579             AC026150.7         108814-108898
            580-689             AC026150.7         108994-109103
            690-776             AC026150.7         110153-110239
            777-884             AC026150.7         110346-110453
            885-972             AC026150.7         110649-110736
            973-1229            AC026150.7         111113-111369
            1230-1298           AC026150.7         111625-111693
            1299-1374           AC026150.7         112944-113019
            1375-1466           AC026150.7         113451-113542
            1467-1567           AC026150.7         114117-114217
            1568-1665           AC026150.7         114300-114397
            1666-1821           AC026150.7         114493-114648
            1822-3983           AC026150.7         114733-116894
            3984-5188           AC091057.6         141751-142955       c
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q13.2"
     gene            1..5188
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /note="golgin A8 family member H"
                     /db_xref="GeneID:728498"
                     /db_xref="HGNC:HGNC:37443"
     exon            1..146
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     CDS             99..1997
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /note="golgi autoantigen, golgin subfamily a, 6-like 11;
                     Golgin subfamily A member 8-like protein 1"
                     /codon_start=1
                     /product="golgin subfamily A member 8H"
                     /protein_id="NP_001269419.1"
                     /db_xref="CCDS:CCDS61576.1"
                     /db_xref="GeneID:728498"
                     /db_xref="HGNC:HGNC:37443"
                     /translation="MAEETQHNKLAAAKKKLKEYWQKNSPRVPAGANRNRKTNGSVPE
                     KATSGGCQPPGDSATGFHREGPTSSATLKDLESPCQERAVVLDSRSVEISQLKNTIKS
                     LKQQKKQVEHQLEEEKKANNKKQKAKRVLEVQIQTLNIQKGKLNTDLYHMKRSLRYFE
                     EKSKDLAVCLQHSLQRKGELESVLSNVMATQKKKANQLSSRSKARTEWKLEQSMREEA
                     LLKVQLTQLKESFQQVQLERDECAEHLKGERARWQQRMRKMSQEICTLKKEKQQDMRR
                     VEKLERSLSKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQAQVKKNQRISL
                     LNQRQEERIQEQEERLRKQEERIQEQHKSLQQLAKPQSVFEEPNNENKNALQLEQQVK
                     ELQEKLGEEHLEAASQQNQQLTAQLSLMALPGEGHGGEHLDSEGEEAPRPMPSVPEDP
                     ESREAMSSFMDHLEEKADLSELVKKKELCFIHHWRDRCHQKTHHLLSEPGGRAKDAAL
                     GGGHHQAGAQGGDEGEAAGAAADGIAAYSNYNNGHRKFLAAAHNSADEPGPGAPAPQE
                     LGAADKHGDLCEVSLTSSAQGEAREDPLLDKPTAQPIVQDHQEHPGLGSNCCVPLLCW
                     AWLPRRRR"
     exon            147..266
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            267..326
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            327..407
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            408..446
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            447..494
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            495..579
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            580..689
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            690..776
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            777..884
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            885..972
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1229
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1298
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..1374
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1375..1466
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1467..1567
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1568..1665
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1821
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     exon            1822..5188
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5165..5170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /note="hexamer: AATAAA"
     polyA_site      5188
                     /gene="GOLGA8H"
                     /gene_synonym="GOLGA6L11"
                     /note="major polyA site"
ORIGIN      
        1 actcacacag ctgcctggta ggtgactgga ggccttgatt ggttctcatt gagattttgc
       61 tgctgtgacc ccaaccctgc ctccctcccc accctgcgat ggcagaagaa actcaacaca
      121 acaaattggc tgcagccaag aaaaagttaa aagaatattg gcagaaaaac agccctagag
      181 ttccagcagg agcgaacagg aacaggaaaa caaatggcag tgtccctgag aaagccactt
      241 ctggtggttg ccagccacct ggggattcag caacaggttt ccacagggaa ggccctacat
      301 catctgctac cctgaaagat ctggagagcc cgtgccaaga acgagcagta gtcctggatt
      361 caaggtccgt agaaatcagt caactgaaga acaccatcaa atctctgaaa caacagaaga
      421 aacaagtgga acatcagctg gaagaagaaa agaaagcaaa caacaagaaa cagaaagcca
      481 aaagggtgct agaggttcaa atccagacat tgaacataca gaaagggaaa ctaaatacgg
      541 acctgtacca catgaaacgt tctctcagat actttgaaga aaagtccaag gatctggctg
      601 tctgcctgca acattcattg cagcgtaaag gagagttaga gagtgttctc tctaatgtca
      661 tggccacaca gaagaagaag gcaaaccagt tgtccagccg cagcaaagca cgtacggagt
      721 ggaagttaga gcagtccatg cgggaggagg cactactgaa agtgcagctg acacagttga
      781 aggagtcatt tcaacaagtc caattagaaa gagatgagtg tgctgaacat ctaaaaggag
      841 agagggcccg gtggcagcag aggatgagaa aaatgtcgca ggagatttgc acattaaaga
      901 aagagaagca gcaagatatg cgtcgggtag agaagctgga gaggagcttg tccaaactca
      961 aaaaccagat ggctgaaccc ttgcccccgg agcccccagc agtgccctct gaggtggagc
     1021 tgcagcacct gaggaaggaa ctagagagag tggcaggaga gctccaggcc caggtcaaaa
     1081 agaatcagcg cataagtctc ctgaaccagc gacaagaaga gaggattcag gagcaggaag
     1141 agaggcttcg gaagcaggag gagaggattc aggagcagca caagagcctt cagcagctgg
     1201 ccaagccaca gagcgtcttc gaggagccga acaatgagaa caagaacgca ctgcagttgg
     1261 agcagcaagt aaaggagcta caggagaagc ttggcgagga gcacctggaa gctgccagcc
     1321 agcagaacca gcagctaacg gcccagctga gcctcatggc tctccctggg gaaggacacg
     1381 gaggagaaca tctggacagt gagggggagg aggcacctcg gcccatgccg agtgtcccag
     1441 aggacccgga gagcagggag gccatgagca gctttatgga ccacctggag gagaaggcag
     1501 acctgagtga gctggtgaag aaaaaagaac tctgcttcat ccaccactgg cgagacagat
     1561 gccatcagaa aacccatcac cttttatcag aaccaggggg ccgtgccaaa gatgcggcac
     1621 tgggaggagg acaccatcag gctggagctc agggaggaga tgaaggtgaa gctgctggag
     1681 ctgcagcaga tggtattgcg gcttacagca actacaacaa tgggcacaga aaattcctgg
     1741 ccgctgccca caactctgct gatgagcccg gtccaggagc cccagccccc caggagcttg
     1801 gggctgcaga caagcatggt gatctttgtg aggtgagcct cacctcctct gcccaaggag
     1861 aggccaggga ggatcctctc cttgacaagc ctactgcaca gccgatcgtg caggaccacc
     1921 aggagcaccc aggcttgggc agcaactgct gtgtgccatt gttgtgctgg gcttggctgc
     1981 caagaagaag gagataaaca tcaccatcct caaagagctg ctcaagaaat ttttaaataa
     2041 gaaaccaagt tatggggtta atctcctaca caattcattt acttcctttg aatgttagag
     2101 tcactcatga ttatttgttt ttctaattta tagttttaag tttatttgta aaaagttaaa
     2161 agagagtggg tgtctgtggc tctcactgat gttcactctg gcatccttta gcatttttct
     2221 tttttaattt cataattgta ggtcattagc gtgcatatcg agtttgccct tacgtggtgg
     2281 gagttcaaac acacaaagac ccactctttg cccaaaactg ttctctttgg tttggaatag
     2341 gctgccatgc ttttttaatg ttattgcagc atgtacattc actacagaat tcagacaaaa
     2401 tttgcctatg ttctgctgtt gtttgatcta atcttaatca cagtgagctc ttcattagct
     2461 caatatgtag tttgccccca agtgtgcact gtttattact ttgtaatatg ccactatgag
     2521 tactgacatt tagagttgtt taaaggccaa gaactggaaa cagcctttcc tccattttct
     2581 gtgtattggt gatgggagtg ataacctttt gggggagctt tttaaatctc acagaagagg
     2641 aaagtggcct cctctggcag gtacgtgcag gatagagtgt gtttcatctg ttccggtgcc
     2701 aggaattagc agtgtattat ggtggttccc ttaggatttg tatgtgctct gggctcatga
     2761 agatactgca tcatgagctg cagcagttgc actctttttc gatgacctaa aaagggctta
     2821 tttctgagga atgaaaggtt cccatcattg actgtggatg tggaaatcct ttcctagctt
     2881 agagcatttg tatctacaat acattttaaa gtcagagttc atgttacctg ttttaatcac
     2941 atgactacat gtcccagtac acaaaagggc actggttggc attcttctta atgtatttag
     3001 tgaagatcat aagaaatcct ttatgagttc aaacgtccct ggaacaggca tacaggctct
     3061 agtcaagaat gaattagagt gaaggaaagc tgtgtgacac ctggcattcc tctctgttca
     3121 cggagattct ttgaggcttg aagattgatt ttaccatcta gacctctttg gctaatacct
     3181 attcttcaac caccttggtt actctgacat aggaatttac ttctttttcc ttgaatggac
     3241 aacactttaa aaaataatag aaacattatt ataaactaat atatgtgaga tacttagttg
     3301 aaacaaaaag gagttttagt agacggtatt gtactctctt tgaaaatcaa ggagaagttt
     3361 atgaaactta aaatgtgtac aaactgcagt gcaatctact gttcgtgaat gtcaatgtat
     3421 tatcaggaaa cgtgtctata caatcacaga gctatatttt ctcacagact tctttacaaa
     3481 gtgaaatatg tttttgtacc tctgggtttc tgttcgggac atattttgtg cgatatttat
     3541 gtgattgtgc ctatgcatga tgaatgaatg catttcagtt gtatattgcc taaatcgtaa
     3601 cttgatgatg cttgggaaag actcaacagt tcaaacttca tgaagttcta atgtctgtgt
     3661 tccaaaacac atcacattgt taggatgcag ggagataggt gtgtgtgctc cctgcggtgg
     3721 ggatttctag ttactagatc atctccattt ttagcatttg gcatcctcat gatacttcta
     3781 taaatatgac attaacagga gagcaacaat acgattttac cgatggaata acagatttgc
     3841 tggcattcac tgaaagagtg caaatattcg gtccttgtga cttccactga ctcttccaaa
     3901 ttttatgaat gtatcaatgt attagataaa cccagtttca gaatgataaa gaaaaaatct
     3961 tagaccaaat aatgcggcta attaacagtg gtacgaattg tagcccgtgg gtttaaaatg
     4021 cacttaaagt cctgttctcg ccttttattt tctgaacttg ccgcttttgc attctttgag
     4081 ttcagtttaa agacagttac tttaagagca ttttaaaccc tcgggctaga aatcggacca
     4141 ctgttaatca gccacattat ttggtctaac gttttttctt ttatcattct gaaactgggt
     4201 ttatctaata cattgataaa ttattgcaaa ggtactttta tcgttgaaat cacttcactt
     4261 ttaccctgat aaatatcagt gactagaatg accttcggat agtgtttagc atctgtaacc
     4321 aatctgacaa taatgtgttc atgaggtgcc tatggattaa atcacacact ggcatattta
     4381 agctgaaggt cagtctggaa aataaattta ctatattgac tgaaatacca ctctttgtgt
     4441 aggtatttgt catatattta agaaaaagct aaaaagaatg gaaattgtat gacaataact
     4501 caagtctttc tccaaagtgc atgcagtctt ttgcgatacc tcattcagcc gagtatttgt
     4561 gctcttcctc attcagtata aggcagcttt cagtttgctt agaaggcaac attggaatgt
     4621 tagagttcat cagaaacata gaattttaaa ctgtgagttc cactgaatac attttaattt
     4681 ctgtaggaag aatcaaaaca cctatttaaa gatggcaata tataataatc attttaaaag
     4741 tatttgatta aacctgataa ttttccagaa atgaaaaaaa aaatcagctc taaaaccaaa
     4801 gctgatttta gaaaatttga aaatgtaaat cagccctatc cataatatag tttctctaaa
     4861 actttatttt aaagagtcat tttaaaataa tataactatt aaaaaatgta actgctatct
     4921 taatgttctg aaataattta aaacatttta aaatatgaat actgtagtat aaaagaaaga
     4981 aatggtggga acgaaaagca gagaaagaaa tgccaattcc agtccaaagt tttatttgcc
     5041 aagttttctt agaatgaatt ttaccagttt atgaattatt gtaaacagaa tgtgtcatgg
     5101 aaatactgaa agatttttcc ctagagtggc cttattgact gctggtgtga tgccactgta
     5161 atgtaataaa ttattaaatt gtttctaa
//
