LOCUS       NM_001350919            4971 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens golgin A8 family member G (GOLGA8G), transcript
            variant 1, mRNA.
ACCESSION   NM_001350919
VERSION     NM_001350919.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4971)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4971)
  AUTHORS   Chen,S., Fragoza,R., Klei,L., Liu,Y., Wang,J., Roeder,K., Devlin,B.
            and Yu,H.
  TITLE     An interactome perturbation framework prioritizes damaging missense
            mutations for developmental disorders
  JOURNAL   Nat Genet 50 (7), 1032-1040 (2018)
   PUBMED   29892012
REFERENCE   3  (bases 1 to 4971)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138749.6.
            
            On Dec 28, 2020 this sequence version replaced NM_001350919.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA1968189, SAMEA1968968
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000525590.3/ ENSP00000458130.1
            RefSeq Select criteria :: based on manual assertion, conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC138749.6         63977-64122
            147-266             AC138749.6         65820-65939
            267-326             AC138749.6         66525-66584
            327-407             AC138749.6         66768-66848
            408-446             AC138749.6         67703-67741
            447-494             AC138749.6         68015-68062
            495-579             AC138749.6         68151-68235
            580-689             AC138749.6         68331-68440
            690-779             AC138749.6         69460-69549
            780-887             AC138749.6         69656-69763
            888-975             AC138749.6         69959-70046
            976-1232            AC138749.6         70437-70693
            1233-1301           AC138749.6         70961-71029
            1302-1377           AC138749.6         72401-72476
            1378-1469           AC138749.6         72914-73005
            1470-1570           AC138749.6         73580-73680
            1571-1671           AC138749.6         73763-73863
            1672-1824           AC138749.6         73953-74105
            1825-4971           AC138749.6         74191-77337
FEATURES             Location/Qualifiers
     source          1..4971
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q13.1"
     gene            1..4971
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /note="golgin A8 family member G"
                     /db_xref="GeneID:283768"
                     /db_xref="HGNC:HGNC:25328"
     exon            1..146
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..2009
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /note="isoform 1 is encoded by transcript variant 1; golgi
                     autoantigen, golgin subfamily a, 8G; putative golgin
                     subfamily A member 8F/8G; putative golgin subfamily A
                     member 8G"
                     /codon_start=1
                     /product="putative golgin subfamily A member 8G isoform 1"
                     /protein_id="NP_001337848.1"
                     /db_xref="CCDS:CCDS86439.1"
                     /db_xref="GeneID:283768"
                     /db_xref="HGNC:HGNC:25328"
                     /translation="MWPQARLPPHPAMAEETRQSKLAAAKRKLKEYWQRNSPGVPAGA
                     KRNRKTNGSIHETATSGGCHSPGDSATGIHGESPTSSATLKDLESPCQELAVVPDSRS
                     VKVSQLKNTIKSLKQQNKQVEHQLEEEKKANNEKQKAERELEVQIQRLNIQKGKLNTD
                     LYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALSAVTATQKKKAERQFSSRSKAR
                     MEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEYAEHLKGERARWQQRMRKMSQEV
                     CSLKKEKKHDKYRVEKLERSLSKLKHQMAEPLPPEPPAVPSEVELQHLRKELERVAGE
                     LQAQVEYNQRISLLNEGQKERLREQEERLQEQQERLPEQEERLQQLAEPQNSFKELNN
                     ENKSVLQLEQQVKELQEKLGKERLEAASQQKQQLTAQLSLMALPGEGDGGGHLDSEGE
                     EAPRPIPSIPQDLESREAMSGFMDHLEEKADLSELVEKEELGFFQYYRERCHQKVYHP
                     ITKPGGSAKDAAPGGGHHQAGPGQGGDEGEAAGAAGDGVAAGGDYKGHSKFLVTAQNP
                     AHEPSPGAPAPQELGAAHKHGDLCEVSLTDSVEPVQGEAREGSPHDNPTAQPIVQDHQ
                     EHPGLGSNCCVPFFCWAWLPRRRR"
     exon            147..266
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            267..326
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            327..407
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            408..446
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            447..494
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            495..579
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            580..689
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            690..779
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            780..887
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            888..975
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            976..1232
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..1301
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1377
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1378..1469
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1570
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1571..1671
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1824
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     exon            1825..4971
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4192..4197
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /note="hexamer: AATAAA"
     polyA_site      4216
                     /gene="GOLGA8G"
                     /gene_synonym="GOLGA8F"
                     /note="major polyA site"
ORIGIN      
        1 agtcgcacag ctacctggta ggtgactgga ggtgttgatc agtgcttggt gggattttgc
       61 tgatgtggcc ccaagcccgc ctccctcccc accctgcgat ggcagaagaa actcgacaaa
      121 gtaaattggc agcagccaag agaaagttaa aagaatattg gcagagaaac agccctggtg
      181 ttccagcagg agccaagagg aacaggaaaa caaatggcag catccatgag acagccactt
      241 ctggtggttg ccactcacct ggagattcag caacaggtat ccacggggag agccctacat
      301 catctgctac cctgaaggat ctggagagcc cgtgccaaga actagcagta gtcccagact
      361 cgaggtccgt aaaagtcagt caactgaaga acaccatcaa atctttgaaa caacagaata
      421 aacaagtgga acatcagctg gaagaagaaa agaaagcaaa caacgagaaa cagaaagccg
      481 aaagggagct agaggttcaa atccagagat tgaacataca gaaagggaaa ctaaatacgg
      541 acctgtacca cacgaaacgt tctctcagat actttgaaga agagtccaag gatctggccg
      601 tccgtctgca acattcattg cagcgtaaag gagagttaga gcgggctctc tctgctgtca
      661 ccgccacaca gaagaagaag gcggagaggc agttctccag ccgcagtaaa gcacgtatgg
      721 agtggaagtt agagcagtcc atgcgggagc aggcactgct gaaagcgcag ctgacacagt
      781 tgaaggagtc acttaaagaa gtccagctag agagggatga atatgctgaa catctaaaag
      841 gagagagggc ccggtggcag cagaggatga gaaaaatgtc gcaggaggtt tgctcgttga
      901 agaaggagaa gaagcatgat aaatatcggg tagagaagct ggagaggagc ttgtccaaac
      961 tcaaacacca gatggctgaa cctctgcccc cggagccccc agcagtgccc tctgaggtgg
     1021 agctgcagca cctgaggaag gaactagaga gagtggcagg agagctccag gcccaggtgg
     1081 agtacaatca gcgcataagt ctcctgaatg aggggcaaaa ggagaggctt cgggagcagg
     1141 aggagaggct tcaggagcag caggagaggc ttccagagca ggaggagagg cttcagcagc
     1201 tggccgagcc acagaacagc ttcaaggagc tgaacaatga gaacaagagc gtactacagt
     1261 tggagcagca agtaaaggag ctgcaggaga agctaggcaa ggagcgtctg gaagctgcga
     1321 gccagcagaa acagcagcta acggcccagt tgagcctcat ggctctccct ggggaaggag
     1381 atggaggagg acatctggac agtgaggggg aggaggcacc tcggcccatt cctagcatcc
     1441 cacaggacct ggagagcagg gaggccatga gcggctttat ggaccacctg gaggagaagg
     1501 cagacctgag tgagctggtg gagaaagaag aacttggatt cttccagtac tacagagaga
     1561 gatgccatca gaaagtttat caccctataa caaagccagg gggcagtgcc aaagatgcag
     1621 caccgggagg aggacaccat caggctggcc ctggacaggg aggagatgaa ggtgaagctg
     1681 ctggagctgc aggagatggt gttgcagctg gtggcgacta caagggacac agcaaattct
     1741 tggtgactgc ccagaaccct gctcatgagc ccagtccagg agccccagcc ccccaggagc
     1801 ttggggctgc ccacaagcat ggtgatcttt gtgaggtgag cctcactgac agcgtggagc
     1861 ctgtgcaagg agaggccagg gagggttctc cccacgacaa ccctactgca cagccgatcg
     1921 tgcaggacca ccaggagcac ccaggcttgg gcagcaactg ctgtgtgcca ttcttttgct
     1981 gggcttggct gccaagaaga aggagataaa catcaccatc gtcaaagagc tgctgaagaa
     2041 atttttaaaa aagaaacaaa gttatggggt taatctccta cacaattcat ttacttcatt
     2101 tgaatgttat agccacttat gattatttgt gtttctaatt tatagtttaa gttcatttgt
     2161 aaatagttaa aagagagtgg gtctctgtgg ctttcactga tgttcactct ggcatacttt
     2221 cgcaattttc tttttcaatt tcataattgt aggtcattag catgcatatt gagtttgccc
     2281 ttacgtggtg ggagttcaaa cacacaaaga cccactattt gcacaaaact attcttgctg
     2341 gtttggaata ggctgccatg tgtttttaat gttattgcag catgtatatt cattacagaa
     2401 ttcagataaa atgtgcctat gttctgctgt tgtttgatct aatcttaatc acagtgagct
     2461 cttcattagc acaatatgtg gtttgcccca agtgtgcact atttaatact ttgtaatatg
     2521 ccaccaagag tactgacatt tagagttgtt taaaggccga gaactggaaa cagccttttc
     2581 ctcattttct gtgtattggt gatgggagta ataacatttt gggggagctt tttaaatttc
     2641 acagaagagg aaagttgcct gctctggcag gtatgtgcaa gatagagtgt gtttcatttg
     2701 ttctgttgcc aagaattagt gctgtactat tgtagttcct ttaggatttg tatgtgctct
     2761 gggctcatga agatattgca tcatgagctt cagcagttgt actctttttt gatgacctaa
     2821 aaagggctta tttctgagga atgaaaggtt cccatcattg actacggttg tggaaaacct
     2881 ttcctagctt agagcatttg tatctatatt ttaaagtcag agttcatgtt acctgtttta
     2941 atcacatgac tgcatgtccc agtacacaaa agggcactgg ttggcattct tcttaatgta
     3001 tttagtaaag atcataagaa atcctttaag agttcaaatg tccctggaac aggcatacag
     3061 gctctagtca agaatgaatt agagtgaagg aaagctgtgt gacacctggc attcctctgt
     3121 tcatggagct tctttgaggc ttgaagattg attttaccat ctagaccact ctgcctattc
     3181 ttcaaccacc ttggttactt tgacatagga attgacttct tttccttgaa tggaaaacac
     3241 tttgaaataa taataaacat tgttataaac taatatatgt gagagtgctt agttgaaaca
     3301 aaaaggagtt ttagtagaca gtattatact atctttgaaa atcaaggaga agtttatgca
     3361 acttaaaatg tgtacaaact gcagtgcaat ctactgttgg tgaatgtcag tgtattatca
     3421 ggaaacatgt ctatacaatc acagagttat atttcctcac aaacttcttt gtgaagagtg
     3481 aaatgtgttt ctgtacctct gggtttcact tacgggcata ttttgtgcag tatttatgtg
     3541 attgtgccta tgcatgatga atgaatgaat ttcagttgta cattgcctaa atcataactt
     3601 gatgatgctt gggaaagact caacagttaa aacttcatga agttctaatg tctgtgttcc
     3661 aaaacacatc acattattag gatgtaggga gatatgtatg tgtgctccct ggggtgggga
     3721 tttctagtta ctagaccatc tccattttta gcatttggca tcctcatgat acttttataa
     3781 atacgacatt aacaggagag cagcagtacg attttgccga tggaataaca gatttgccgg
     3841 caatcactga aagagtgcaa acatcgggtc cttgtgactt caacggactc ttccaaattg
     3901 tatgaatgta tcaatgtatt agataaaccc agtttcagaa tgataaagaa aaaatgttag
     3961 accaaataat gcggctagtt aacagtggta cgatttctcg cccgtggctt taaaatgcac
     4021 ttaaagtcct gtccttgcct tttattttct gaacttgatg tttttgcatt ctttgagttc
     4081 agtttaaaga caactacgag catctgtaac caatctgaca ataatgtgtt catcaggtgc
     4141 ctgtggatta aatcacatac tggcatattt aagctgaatg tcaatctgga aaataaattg
     4201 actgtattaa cggaaatacc actctttgtg tagatatttg tcgtatattg aagaaaaagc
     4261 taaaaagaat ggaaatcgca tgactataac ttaagtcttt cttcaaagtg catgcagtct
     4321 tttgcgatac ctcattcagc caagtattgg tattcttcct cattcggtat aaggcagctt
     4381 tcaatttgct tagagggcaa cattggaagg ttagagttca tcagaaacag aattctaaaa
     4441 tgtgagttca attcaataaa tttgaatttc tgtaggaaga atcaaatcac cgatttaaag
     4501 attgcaatat ataataatca tttttaaagt attggattaa atctgatagg ttttccagaa
     4561 atgaacaaaa atcagctcta aaaccaaagc tgatttttag aaaatttgaa aatgtaaatc
     4621 agccctatcc atactatagt ttctctaaaa ctttatctga aagagtcatt ttaaaataac
     4681 tattaaacaa tgtaactgct atcttaatgt tctgaaataa gttaaaacat tttaaaatat
     4741 gaatactgta aaggaaataa acggtgggaa ggaaaagtag agaaagaaat gccaattcca
     4801 gtccaaagct ttatttgcca agttttctta gaatgaattt taccaattta tgaattcttg
     4861 taagcggaat gtaaaacgga aatactgaaa gacttttgcc taaagtggca ttattgactg
     4921 ctggtgtgat gctactgtaa tgtaataaat tattaagttg ttgcaaagtg c
//
