LOCUS       NM_001362980            1956 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens golgin A7 (GOLGA7), transcript variant 5, mRNA.
ACCESSION   NM_001362980 XM_024447175
VERSION     NM_001362980.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1956)
  AUTHORS   Zeng,X.T., Yu,X.X. and Cheng,W.
  TITLE     Correction to: The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2
            spike (S) protein and their effects on S protein's subcellular
            localization, palmitoylation and pseudovirus entry
  JOURNAL   Virol J 19 (1), 25 (2022)
   PUBMED   35115020
  REMARK    Correction to:[Virol J. 2021 Dec 27;18(1):257. doi:
            10.1186/s12985-021-01722-w.. PMID: 34961524]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1956)
  AUTHORS   Zeng,X.T., Yu,X.X. and Cheng,W.
  TITLE     The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike (S) protein
            and their effects on S protein's subcellular localization,
            palmitoylation and pseudovirus entry
  JOURNAL   Virol J 18 (1), 257 (2021)
   PUBMED   34961524
  REMARK    GeneRIF: The interactions of ZDHHC5/GOLGA7 with SARS-CoV-2 spike
            (S) protein and their effects on S protein's subcellular
            localization, palmitoylation and pseudovirus entry.
            Erratum:[Virol J. 2022 Feb 3;19(1):25. doi:
            10.1186/s12985-022-01750-0.. PMID: 35115020]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1956)
  AUTHORS   Wu,Z., Zhang,Z., Wang,X., Zhang,J., Ren,C., Li,Y., Gao,L.,
            Liang,X., Wang,P. and Ma,C.
  TITLE     Palmitoylation of SARS-CoV-2 S protein is essential for viral
            infectivity
  JOURNAL   Signal Transduct Target Ther 6 (1), 231 (2021)
   PUBMED   34117209
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1956)
  AUTHORS   Stukalov,A., Girault,V., Grass,V., Karayel,O., Bergant,V.,
            Urban,C., Haas,D.A., Huang,Y., Oubraham,L., Wang,A., Hamad,M.S.,
            Piras,A., Hansen,F.M., Tanzer,M.C., Paron,I., Zinzula,L.,
            Engleitner,T., Reinecke,M., Lavacca,T.M., Ehmann,R., Wolfel,R.,
            Jores,J., Kuster,B., Protzer,U., Rad,R., Ziebuhr,J., Thiel,V.,
            Scaturro,P., Mann,M. and Pichlmair,A.
  TITLE     Multilevel proteomics reveals host perturbations by SARS-CoV-2 and
            SARS-CoV
  JOURNAL   Nature 594 (7862), 246-252 (2021)
   PUBMED   33845483
REFERENCE   5  (bases 1 to 1956)
  AUTHORS   Gordon,D.E., Hiatt,J., Bouhaddou,M., Rezelj,V.V., Ulferts,S.,
            Braberg,H., Jureka,A.S., Obernier,K., Guo,J.Z., Batra,J.,
            Kaake,R.M., Weckstein,A.R., Owens,T.W., Gupta,M., Pourmal,S.,
            Titus,E.W., Cakir,M., Soucheray,M., McGregor,M., Cakir,Z., Jang,G.,
            O'Meara,M.J., Tummino,T.A., Zhang,Z., Foussard,H., Rojc,A.,
            Zhou,Y., Kuchenov,D., Huttenhain,R., Xu,J., Eckhardt,M.,
            Swaney,D.L., Fabius,J.M., Ummadi,M., Tutuncuoglu,B., Rathore,U.,
            Modak,M., Haas,P., Haas,K.M., Naing,Z.Z.C., Pulido,E.H., Shi,Y.,
            Barrio-Hernandez,I., Memon,D., Petsalaki,E., Dunham,A.,
            Marrero,M.C., Burke,D., Koh,C., Vallet,T., Silvas,J.A.,
            Azumaya,C.M., Billesbolle,C., Brilot,A.F., Campbell,M.G.,
            Diallo,A., Dickinson,M.S., Diwanji,D., Herrera,N., Hoppe,N.,
            Kratochvil,H.T., Liu,Y., Merz,G.E., Moritz,M., Nguyen,H.C.,
            Nowotny,C., Puchades,C., Rizo,A.N., Schulze-Gahmen,U., Smith,A.M.,
            Sun,M., Young,I.D., Zhao,J., Asarnow,D., Biel,J., Bowen,A.,
            Braxton,J.R., Chen,J., Chio,C.M., Chio,U.S., Deshpande,I., Doan,L.,
            Faust,B., Flores,S., Jin,M., Kim,K., Lam,V.L., Li,F., Li,J.,
            Li,Y.L., Li,Y., Liu,X., Lo,M., Lopez,K.E., Melo,A.A., Moss,F.R.
            3rd, Nguyen,P., Paulino,J., Pawar,K.I., Peters,J.K., Pospiech,T.H.
            Jr., Safari,M., Sangwan,S., Schaefer,K., Thomas,P.V., Thwin,A.C.,
            Trenker,R., Tse,E., Tsui,T.K.M., Wang,F., Whitis,N., Yu,Z.,
            Zhang,K., Zhang,Y., Zhou,F., Saltzberg,D., Hodder,A.J.,
            Shun-Shion,A.S., Williams,D.M., White,K.M., Rosales,R., Kehrer,T.,
            Miorin,L., Moreno,E., Patel,A.H., Rihn,S., Khalid,M.M.,
            Vallejo-Gracia,A., Fozouni,P., Simoneau,C.R., Roth,T.L., Wu,D.,
            Karim,M.A., Ghoussaini,M., Dunham,I., Berardi,F., Weigang,S.,
            Chazal,M., Park,J., Logue,J., McGrath,M., Weston,S., Haupt,R.,
            Hastie,C.J., Elliott,M., Brown,F., Burness,K.A., Reid,E.,
            Dorward,M., Johnson,C., Wilkinson,S.G., Geyer,A., Giesel,D.M.,
            Baillie,C., Raggett,S., Leech,H., Toth,R., Goodman,N., Keough,K.C.,
            Lind,A.L., Klesh,R.J., Hemphill,K.R., Carlson-Stevermer,J., Oki,J.,
            Holden,K., Maures,T., Pollard,K.S., Sali,A., Agard,D.A., Cheng,Y.,
            Fraser,J.S., Frost,A., Jura,N., Kortemme,T., Manglik,A.,
            Southworth,D.R., Stroud,R.M., Alessi,D.R., Davies,P., Frieman,M.B.,
            Ideker,T., Abate,C., Jouvenet,N., Kochs,G., Shoichet,B., Ott,M.,
            Palmarini,M., Shokat,K.M., Garcia-Sastre,A., Rassen,J.A.,
            Grosse,R., Rosenberg,O.S., Verba,K.A., Basler,C.F., Vignuzzi,M.,
            Peden,A.A., Beltrao,P. and Krogan,N.J.
  CONSRTM   QCRG Structural Biology Consortium; Zoonomia Consortium
  TITLE     Comparative host-coronavirus protein interaction networks reveal
            pan-viral disease mechanisms
  JOURNAL   Science 370 (6521) (2020)
   PUBMED   33060197
REFERENCE   6  (bases 1 to 1956)
  AUTHORS   Talmud,P.J., Drenos,F., Shah,S., Shah,T., Palmen,J., Verzilli,C.,
            Gaunt,T.R., Pallas,J., Lovering,R., Li,K., Casas,J.P., Sofat,R.,
            Kumari,M., Rodriguez,S., Johnson,T., Newhouse,S.J., Dominiczak,A.,
            Samani,N.J., Caulfield,M., Sever,P., Stanton,A., Shields,D.C.,
            Padmanabhan,S., Melander,O., Hastie,C., Delles,C., Ebrahim,S.,
            Marmot,M.G., Smith,G.D., Lawlor,D.A., Munroe,P.B., Day,I.N.,
            Kivimaki,M., Whittaker,J., Humphries,S.E. and Hingorani,A.D.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am J Hum Genet 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 1956)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   8  (bases 1 to 1956)
  AUTHORS   Swarthout,J.T., Lobo,S., Farh,L., Croke,M.R., Greentree,W.K.,
            Deschenes,R.J. and Linder,M.E.
  TITLE     DHHC9 and GCP16 constitute a human protein fatty acyltransferase
            with specificity for H- and N-Ras
  JOURNAL   J Biol Chem 280 (35), 31141-31148 (2005)
   PUBMED   16000296
  REMARK    GeneRIF: Data show that H- and N-Ras are palmitoylated by a human
            protein palmitoyltransferase encoded by the ZDHHC9 and GCP16 genes.
REFERENCE   9  (bases 1 to 1956)
  AUTHORS   Ohta,E., Misumi,Y., Sohda,M., Fujiwara,T., Yano,A. and Ikehara,Y.
  TITLE     Identification and characterization of GCP16, a novel acylated
            Golgi protein that interacts with GCP170
  JOURNAL   J Biol Chem 278 (51), 51957-51967 (2003)
   PUBMED   14522980
  REMARK    GeneRIF: results indicate that GCP16 is the acylated membrane
            protein, associated with GCP170, and possibly involved in vesicular
            transport from the Golgi to the cell surface
REFERENCE   10 (bases 1 to 1956)
  AUTHORS   Jia,L., Young,M.F., Powell,J., Yang,L., Ho,N.C., Hotchkiss,R.,
            Robey,P.G. and Francomano,C.A.
  TITLE     Gene expression profile of human bone marrow stromal cells:
            high-throughput expressed sequence tag sequencing analysis
  JOURNAL   Genomics 79 (1), 7-17 (2002)
   PUBMED   11827452
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC009630.14, BP341683.1, HY131836.1, BC001227.2, AF068291.1,
            AV650886.1, AF125102.1 and BG939345.1.
            
            On Aug 13, 2020 this sequence version replaced NM_001362980.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.2094347.1,
                                           SRR18074969.1932869.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-30                AC009630.14        158014-158043       c
            31-43               BP341683.1         1-13
            44-514              HY131836.1         4-474
            515-1064            BC001227.2         448-997
            1065-1129           AF068291.1         968-1032
            1130-1175           BC001227.2         1063-1108
            1176-1227           AV650886.1         436-487
            1228-1338           BC001227.2         1161-1271
            1339-1742           AF125102.1         1251-1654
            1743-1954           BG939345.1         20-231              c
            1955-1956           BC001227.2         1888-1889
FEATURES             Location/Qualifiers
     source          1..1956
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="8"
                     /map="8p11.21"
     gene            1..1956
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /note="golgin A7"
                     /db_xref="GeneID:51125"
                     /db_xref="HGNC:HGNC:24876"
                     /db_xref="MIM:609453"
     exon            1..108
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     exon            109..241
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..544
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /note="isoform a is encoded by transcript variant 5; Golgi
                     complex-associated protein of 16kDa; golgi autoantigen,
                     golgin subfamily a, 7; golgin subfamily A member 7; golgi
                     complex-associated protein of 16 kDa"
                     /codon_start=1
                     /product="golgin subfamily A member 7 isoform a"
                     /protein_id="NP_001349909.1"
                     /db_xref="CCDS:CCDS34887.1"
                     /db_xref="GeneID:51125"
                     /db_xref="HGNC:HGNC:24876"
                     /db_xref="MIM:609453"
                     /translation="MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRIDRQQFE
                     ETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNE
                     KIYAPQGLLLTDPIERGLRVIEITIYEDRGMSSGR"
     exon            242..394
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     exon            395..496
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     exon            497..559
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     exon            560..1956
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1936..1941
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /note="hexamer: AATAAA"
     polyA_site      1956
                     /gene="GOLGA7"
                     /gene_synonym="GCP16; GOLGA3AP1; GOLGA7A; HSPC041"
                     /note="major polyA site"
ORIGIN      
        1 ggcggtgcga cagcagctgg agggcagagg aggcgggttt gtgtttcccg ggccgaaccg
       61 ggttgtgggg ggcgcggggc ctgggccagg cggcagctaa ggcccgcgcg cggggtgtcc
      121 tgtcctcgcc atgaggccgc agcaggcgcc ggtgtccgga aaggtgttca ttcagcgaga
      181 ctacagcagt ggcacacgct gccagttcca gaccaagttc cctgcggagc tggagaaccg
      241 gattgatagg cagcagtttg aagaaacagt tcgaactcta aataaccttt atgcagaagc
      301 agagaagctc ggcggccagt catatctcga aggttgtttg gcttgtttaa cagcatatac
      361 catcttccta tgcatggaaa ctcattatga gaaggttctg aagaaagtct ccaaatacat
      421 tcaagagcag aatgagaaga tctatgctcc acaaggcctc ctcctgacag accctattga
      481 gcgaggactg cgagttattg aaattaccat ttatgaagac agaggcatga gcagtggaag
      541 ataaaccgaa gaattaaaga tcccacttcc agccgggccc ctcatgtatc cactggccga
      601 ccgcagagtg tccctacctc ctctccagag catcattcct ttctatctgc tgccagagcc
      661 acggtgccat ttactccaag gactcacttt ctaaaattcc acacctggag tgacctctag
      721 tcgctcagca tccactttgt gtctccaaat tgtgtaggac tctgtaatct tttgattagt
      781 ttctgagaaa acacaatgaa gcacttcact tttttttatt caaagccatt taataaaaca
      841 cagttggtca gcccagtgca aagcttgtta tctgccacca gtacatacca ttggttctct
      901 tcattccttg ggccagcttc tcaggtggct ttagacctca acaagccgta tcttcaccag
      961 tgttctatct tgttccccta aattaataaa atgtttttct ccaggatttt ggtgagggtt
     1021 ggctgtggct gtcgttttgc acctcccaga tttcaaagaa ttactggttt taccatgact
     1081 caaatcttaa gatctgtttc tactattcag ttcctcaaac tgaagcttat tgaaaaaaaa
     1141 atgtataatg ttatttgttt tattatagca attatgccta attaaagcag tatttaatgc
     1201 aatttccagt tatttctttg gagaatttta tgtcattgtt ccattacctt gaatgttgga
     1261 aagatatgat acgtgctgct tgttcatcac aaaaatcagt aagcacaata aagtggatgc
     1321 caaaccatca gacacataaa tgttcccgct gtgtccctgg atatggaata agcaggtata
     1381 aaaaatattt taattatagt tttgttataa atataactta tgagaaaaaa atttgatagg
     1441 aataatactg tatattacta atttttaact atccctaagg caaaccttat gacccacaga
     1501 attttctcat atacagtatt cagtgcacag aaatcttatg attggctcaa gtacagtaag
     1561 ttacttctca gtaaaactct caagtctgag tccatatttg tagctctgct tttggctgta
     1621 cgttcctagg atcggggctg cttatgcctt tcgtttatcc ttggggtttg agagcgctgt
     1681 atttgggaga gagtttaaaa atacattagg agagagaaac cattaaaagt ttcactgtca
     1741 gatatattgt aggtgctaat actggatttc gtctcagatt taatttcttt tatgggtctg
     1801 ttagtcattc aacaaatccc ataagtatgt gttaatattt taattgtgta aaactcattt
     1861 gttactttac agcctgtaat agtgtgtctg cattttcaac ctgttgcaat aactttgctg
     1921 aaatattaac acattaataa aacttttctt aaacaa
//
