LOCUS       NM_001267536            4553 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens golgin A6 family like 4 (GOLGA6L4), mRNA.
ACCESSION   NM_001267536 XM_006720634
VERSION     NM_001267536.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4553)
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium
  TITLE     Biological insights from 108 schizophrenia-associated genetic loci
  JOURNAL   Nature 511 (7510), 421-427 (2014)
   PUBMED   25056061
REFERENCE   2  (bases 1 to 4553)
  AUTHORS   Zody,M.C., Garber,M., Sharpe,T., Young,S.K., Rowen,L., O'Neill,K.,
            Whittaker,C.A., Kamal,M., Chang,J.L., Cuomo,C.A., Dewar,K.,
            FitzGerald,M.G., Kodira,C.D., Madan,A., Qin,S., Yang,X., Abbasi,N.,
            Abouelleil,A., Arachchi,H.M., Baradarani,L., Birditt,B., Bloom,S.,
            Bloom,T., Borowsky,M.L., Burke,J., Butler,J., Cook,A.,
            DeArellano,K., DeCaprio,D., Dorris,L. 3rd, Dors,M., Eichler,E.E.,
            Engels,R., Fahey,J., Fleetwood,P., Friedman,C., Gearin,G.,
            Hall,J.L., Hensley,G., Johnson,E., Jones,C., Kamat,A., Kaur,A.,
            Locke,D.P., Madan,A., Munson,G., Jaffe,D.B., Lui,A., Macdonald,P.,
            Mauceli,E., Naylor,J.W., Nesbitt,R., Nicol,R., O'Leary,S.B.,
            Ratcliffe,A., Rounsley,S., She,X., Sneddon,K.M., Stewart,S.,
            Sougnez,C., Stone,S.M., Topham,K., Vincent,D., Wang,S.,
            Zimmer,A.R., Birren,B.W., Hood,L., Lander,E.S. and Nusbaum,C.
  TITLE     Analysis of the DNA sequence and duplication history of human
            chromosome 15
  JOURNAL   Nature 440 (7084), 671-675 (2006)
   PUBMED   16572171
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC136698.6.
            
            On May 17, 2019 this sequence version replaced NM_001267536.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2145544 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000510439.7/ ENSP00000421586.2
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-146               AC136698.6         135312-135457
            147-266             AC136698.6         137125-137244
            267-326             AC136698.6         137867-137926
            327-407             AC136698.6         138112-138192
            408-495             AC136698.6         138857-138944
            496-1490            AC136698.6         139327-140321
            1491-1551           AC136698.6         140588-140648
            1552-1654           AC136698.6         141686-141788
            1655-4553           AC136698.6         141999-144897
FEATURES             Location/Qualifiers
     source          1..4553
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q25.2"
     gene            1..4553
                     /gene="GOLGA6L4"
                     /note="golgin A6 family like 4"
                     /db_xref="GeneID:643707"
                     /db_xref="HGNC:HGNC:27256"
     exon            1..146
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..1787
                     /gene="GOLGA6L4"
                     /note="golgi autoantigen, golgin subfamily a, 6-like 4;
                     putative golgin subfamily A member 6-like protein 4"
                     /codon_start=1
                     /product="golgin subfamily A member 6-like protein 4"
                     /protein_id="NP_001254465.2"
                     /db_xref="CCDS:CCDS73774.1"
                     /db_xref="GeneID:643707"
                     /db_xref="HGNC:HGNC:27256"
                     /translation="MWPQPRFPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGA
                     NRKKKINGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLEDLESQYQELAVALDSSS
                     AIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVE
                     QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQ
                     EDRLHEQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEE
                     RLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLE
                     QERRQEEQERLLERERLLEEVEKLLEQERQQEEQERLLERERLLEEVEKLLEQERRQE
                     EQERLLERERLLDEVEELLDEVEELLEQERLRQQDERLWQQETLQELERLRELERLRE
                     LERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESA
                     AAARPVAGAPVPQGAWMCGQAGWTPQEHPGLSGEAVGTGEAAGGAGEAACHSFRAAEN
                     RELNITII"
     exon            147..266
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            267..326
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            327..407
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            408..495
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            496..1490
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            1491..1551
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1654
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     exon            1655..4553
                     /gene="GOLGA6L4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4534..4539
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA6L4"
                     /note="hexamer: ATTAAA"
     polyA_site      4553
                     /gene="GOLGA6L4"
                     /note="major polyA site"
ORIGIN      
        1 agttgcacag ctgcctggta ggtgactgga ggcattgagc agtgctcact ggtatttcgc
       61 tgatgtggcc ccaaccccgc ttccctcccc accccgcgat gtcagaaaaa acacaacagg
      121 ggaaattggc cgcagccaag aaaaagttaa aagcatattg gcagaggaag agccctggca
      181 ttccagcagg agctaacagg aaaaagaaaa tcaatggcag tagccctgac acagccactt
      241 ctggtggtta ccactcacct ggggattcag caacaggtat ctacggggag ggccgtgcat
      301 cctctactac cctggaggat ctggagagcc agtaccaaga actagcagtg gccctggatt
      361 caagctccgc aataatcagt caactcactg aaaacatcaa ttcactggtt cgcacatcta
      421 aggaggagaa gaagcatgag atacatctgg tacagaagct tgggaggagc ttgttcaaac
      481 tcaaaaacca gacggctgaa cccctggccc cagagccccc agcagggcca tctaaggtag
      541 agcagctaca agatgagacc aaccacctaa ggaaggagct agagagtgtg ggaagacagc
      601 tccaggctga ggtggaaaac aatcagatgt tgagtctcct gaacaggaga caggaggaga
      661 ggctacgtga acaggaggag aggctacgtg aacaggagga gaggctacgt gaacaggagg
      721 ataggctaca tgaacaggag gagaggctac gtgaacagga ggagaggctg tgtgaacagg
      781 aggagaggct acgtgaacat gaggagaggc tgtgtgaaca ggaggagagg ctatgtgaac
      841 aggaggagag gctacgtgaa caggaggaga ggctacatga acaggaggag aggctacgtg
      901 aacaggagga gaggctgtgt gaacaggagg agaggctacg tgaacaggag gagaggctgt
      961 gtgaacagga ggagaggcta cgtgaacagg aggagaggct gtgtgaacag gagaagctgc
     1021 cagggcagga gaggctgctg gaagaggtgg agaagctgtt agaacaggag aggcggcagg
     1081 aggagcagga gaggctgctg gagagggaga ggctgctgga agaggtggag aagctgttag
     1141 aacaggagag gcagcaggag gagcaggaga ggctgctgga gagggagagg ctgctggaag
     1201 aggtggagaa gctgttagaa caggagaggc ggcaggagga gcaggagagg ctgctggaga
     1261 gggagaggct gctggacgag gtggaggagc tcctggatga ggtggaggag ctcctggagc
     1321 aggagaggct tcggcaacag gatgagaggc tgtggcagca ggagactctg caggagctgg
     1381 agaggctgcg ggagctggag aggctgcggg agctggagag gatgctggag ctggggtggg
     1441 aagccctgta cgagcagcgg gccgagccac gcagcggctt cgaggagctg aacaacgaga
     1501 acaagagcac actgcagttg gagcagcaag taaaggagct gaagaagtcg ggtggagctg
     1561 aagagccaag aggctccgag tctgcagcag cagccagacc agtagctgga gccccagtcc
     1621 cacaaggagc ttggatgtgc ggacaagcag ggtggactcc ccaggagcac ccaggcttga
     1681 gtggagaagc tgttggtaca ggagaggcgg caggaggagc aggagaggct gcatgccatt
     1741 cttttcgggc tgcggagaac agggagctaa acatcaccat catctaagag cgggtcaagg
     1801 aattgaaaaa aaaaaacaaa acatttaagg ggttaatatc ctacacaatt catttacttc
     1861 atttgaatgt tagagccact tatgtttatt tgtgtttcta atttatagtt taaatttatt
     1921 tgtgtttcta atttatagtt taaatttatt tgtgtttcta atttatagtt taaatttatt
     1981 tgtgtttcta atttataatt taaatttatt tgtaaaaagt taaatgagag tgggtgtttc
     2041 tctcatgttc actctggcat cttttagcat ttttttaatt tgataattat aggacgttag
     2101 catgcatatc gagtttgccc ttatgtggtg ggagttcaaa cacacaaaga cccactgtat
     2161 gcacacaact gttcttgctg gtttgggata ggctgccatg ctttttgaat gttagtacag
     2221 cctgtatatt cattacggaa ttcagataaa atttccttat gttctgctgt tatgtttgat
     2281 cgaatcctaa tcacagtgag ctcttcatta gctcaatatg cagtttgccc tcaagtgcgc
     2341 ggtctattac tttgtaatat gccactgtga gtactgacat ttacagttgt ttaaaggtgg
     2401 agcactggaa acagcctttc cccctttttc tgtgtattgg ggatgggagt aataacattt
     2461 tggggaggtt tttaaatctc ccagaagagg aaagtggcct gctttggcag gtgtgtgcag
     2521 gatagaatat gtttcatttg ttccggtgcc aagaatgagc gctgtactac ggtagttccc
     2581 ttaggatttg tatgtgctct gggctcatga agatactgcc tcatgagctg tggcagttgt
     2641 actctttttt gatgacctga aaagggatta tttctgagga atgaaaggct cccatcatga
     2701 ctgtggatgt ggaaaacctt ttctagctga gagcatttat atctacaata cattttaaag
     2761 tcagcgttca tgttccctgt tttaatcaca tgactacatg tcccagtaca caaaagggca
     2821 ctggttggcg ttctccttaa tgtatttagt aaagatcaga agaaatcctt taagagttta
     2881 aatgcccctg gaacaggcat atacaggctc tagtcaagaa tgaattcgag tgaaggaaag
     2941 ctgtgtgaca cctggcattc ctctgtgttc atggagctta tttgaggcta gaagatggat
     3001 tttaccatct agacctctct ggctaatagc tagtcttcaa ccatctgaca taggaattta
     3061 cttcttttcc ttgaatggag aacactttaa aaataataac aaacattatt ataaactaat
     3121 atatgtgaga gtacttagtt gaaacaaaaa ggagttttag tagacagtat tatactacat
     3181 ttgaaaatca aggagcagtt tatgcaacgt aaaatgttta caaactgcag cgcaatctac
     3241 tgtttgtgac tgtcaaagtg tcatgaggaa agtgtctata caatcacaga gttatatttc
     3301 ctcacaaagt tctttacgaa gagtgaaata tgtttttata cctctcagtt tcagttagag
     3361 gcatattttg tgtaatattt atggcttaaa atggactaaa ggtcctgttc ttgccttgtc
     3421 tgaacttgcc gcttttgcat tctttgagtt cagtttaaag acacttactt taactccatt
     3481 ttaaaccctc gggctagaaa tcgtaccact gttaattagc cacgttattt ggtctaacag
     3541 tttttgttta tcattctgaa actgagctta tctaatacat tgataaatta tttcaaaggt
     3601 atttttatag ttcaaatcgc ttcactttta ccctgacacg tataaatgaa taggaatgac
     3661 cttcagatag cgtttagcaa ctgtaaccaa tctgacaata atgtgttcat caggtacctg
     3721 tggattaaat cacatactgg catatttaag atgaatgtca gtctgaaaaa taaatatact
     3781 atattaattc aaatacgact ctttgtgtag gtattttgtc atatgtttaa gaaaaagcta
     3841 aagagaatgg aaatcctatg acaataactc aagtctttct tcaaagtgca tgcagtcttt
     3901 tgcagtacct cattcagcca agtatttgtt ctctacctca ttcagtataa ggcagccttt
     3961 aatttgctta gaaggcaaca ttagaaggtt agagttcagc aggaacatag aattttaaaa
     4021 tgtgacttca actgaataaa tttgaatttc tctagggagt aaagaatcaa aacacctatt
     4081 taaagactgc aaaatatgat aattattttt aaagtaattg attaaacctg gtaggttttc
     4141 ccaaaatgaa aaacaatcag ttctaaaacc aaagctgatt tttagaaaat gtgaaaatgt
     4201 aaatcaaccc tatccataat agattctcta aaactttatc ttacagtcac tttcaaataa
     4261 ctattcaaaa atgtaactgc tatattaacg tcttaaaata atttaaaaca ttttaaaata
     4321 tgaatactgt agtttaaaac aaagaatcta ggggaaggaa aagtagacaa agaaatgcca
     4381 attccagtcc aaagctgtat ttgccaagtt ttcttagaat gacttttacc gatttatgaa
     4441 ttcttataca cagaatgcat aatggaaata ctgatttttg tctaaagtgg cattattgac
     4501 tgcttctgtg atgctactgt aatgtaatac attattaaat tgtttcaagg tgc
//
