LOCUS       NM_002077               4877 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens golgin A1 (GOLGA1), mRNA.
ACCESSION   NM_002077
VERSION     NM_002077.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4877)
  AUTHORS   Grimaldi,G., Filograna,A., Schembri,L., Lo Monte,M., Di Martino,R.,
            Pirozzi,M., Spano,D., Beccari,A.R., Parashuraman,S., Luini,A.,
            Valente,C. and Corda,D.
  TITLE     PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of Golgin-97
            is required for E-cadherin transport from Golgi to plasma membrane
  JOURNAL   Proc Natl Acad Sci U S A 119 (1) (2022)
   PUBMED   34969853
  REMARK    GeneRIF: PKD-dependent PARP12-catalyzed mono-ADP-ribosylation of
            Golgin-97 is required for E-cadherin transport from Golgi to plasma
            membrane.
REFERENCE   2  (bases 1 to 4877)
  AUTHORS   Shin,J.J.H., Crook,O.M., Borgeaud,A.C., Cattin-Ortola,J.,
            Peak-Chew,S.Y., Breckels,L.M., Gillingham,A.K., Chadwick,J.,
            Lilley,K.S. and Munro,S.
  TITLE     Spatial proteomics defines the content of trafficking vesicles
            captured by golgin tethers
  JOURNAL   Nat Commun 11 (1), 5987 (2020)
   PUBMED   33239640
  REMARK    GeneRIF: Spatial proteomics defines the content of trafficking
            vesicles captured by golgin tethers.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4877)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 4877)
  AUTHORS   Shin,J.J.H., Gillingham,A.K., Begum,F., Chadwick,J. and Munro,S.
  TITLE     TBC1D23 is a bridging factor for endosomal vesicle capture by
            golgins at the trans-Golgi
  JOURNAL   Nat Cell Biol 19 (12), 1424-1432 (2017)
   PUBMED   29084197
  REMARK    Erratum:[Nat Cell Biol. 2018 Feb;20(2):222. doi:
            10.1038/s41556-017-0026-7.. PMID: 29311657]
REFERENCE   5  (bases 1 to 4877)
  AUTHORS   Jing,J., Junutula,J.R., Wu,C., Burden,J., Matern,H., Peden,A.A. and
            Prekeris,R.
  TITLE     FIP1/RCP binding to Golgin-97 regulates retrograde transport from
            recycling endosomes to the trans-Golgi network
  JOURNAL   Mol Biol Cell 21 (17), 3041-3053 (2010)
   PUBMED   20610657
  REMARK    GeneRIF: FIP1/RCP binding to Golgin-97 is required for tethering
            and fusion of recycling endosome-derived retrograde transport
            vesicles to the trans-Golgi network.
REFERENCE   6  (bases 1 to 4877)
  AUTHORS   Luke,M.R., Houghton,F., Perugini,M.A. and Gleeson,P.A.
  TITLE     The trans-Golgi network GRIP-domain proteins form alpha-helical
            homodimers
  JOURNAL   Biochem J 388 (Pt 3), 835-841 (2005)
   PUBMED   15654769
  REMARK    GeneRIF: The ability of the four mammalian GRIP domain proteins,
            p230, golgin-97, GCC88, and GCC185 to interact is reported.
REFERENCE   7  (bases 1 to 4877)
  AUTHORS   Lu,L., Tai,G. and Hong,W.
  TITLE     Autoantigen Golgin-97, an effector of Arl1 GTPase, participates in
            traffic from the endosome to the trans-golgi network
  JOURNAL   Mol Biol Cell 15 (10), 4426-4443 (2004)
   PUBMED   15269279
  REMARK    GeneRIF: Data show that Arl1 regulates the membrane recruitment of
            Golgin-97, which plays a role in transport from the endosome to the
            trans-Golgi network.
REFERENCE   8  (bases 1 to 4877)
  AUTHORS   Lu,L. and Hong,W.
  TITLE     Interaction of Arl1-GTP with GRIP domains recruits autoantigens
            Golgin-97 and Golgin-245/p230 onto the Golgi
  JOURNAL   Mol Biol Cell 14 (9), 3767-3781 (2003)
   PUBMED   12972563
REFERENCE   9  (bases 1 to 4877)
  AUTHORS   Barr,F.A.
  TITLE     A novel Rab6-interacting domain defines a family of Golgi-targeted
            coiled-coil proteins
  JOURNAL   Curr Biol 9 (7), 381-384 (1999)
   PUBMED   10209123
REFERENCE   10 (bases 1 to 4877)
  AUTHORS   Griffith,K.J., Chan,E.K., Lung,C.C., Hamel,J.C., Guo,X., Miyachi,K.
            and Fritzler,M.J.
  TITLE     Molecular cloning of a novel 97-kd Golgi complex autoantigen
            associated with Sjogren's syndrome
  JOURNAL   Arthritis Rheum 40 (9), 1693-1702 (1997)
   PUBMED   9324025
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL451125.7 and AL354928.9.
            
            On May 17, 2019 this sequence version replaced NM_002077.3.
            
            Summary: The Golgi apparatus, which participates in glycosylation
            and transport of proteins and lipids in the secretory pathway,
            consists of a series of stacked cisternae (flattened membrane
            sacs). Interactions between the Golgi and microtubules are thought
            to be important for the reorganization of the Golgi after it
            fragments during mitosis. This gene encodes one of the golgins, a
            family of proteins localized to the Golgi. This encoded protein is
            associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010].
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.103942.1,
                                           SRR1803617.108573.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000373555.9/ ENSP00000362656.4
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL451125.7         24400-24512         c
            114-163             AL451125.7         23535-23584         c
            164-453             AL451125.7         22006-22295         c
            454-544             AL451125.7         14745-14835         c
            545-619             AL451125.7         12645-12719         c
            620-717             AL451125.7         11617-11714         c
            718-750             AL451125.7         10138-10170         c
            751-879             AL451125.7         6524-6652           c
            880-1049            AL451125.7         5152-5321           c
            1050-1161           AL451125.7         4558-4669           c
            1162-1287           AL354928.9         171769-171894       c
            1288-1383           AL354928.9         168245-168340       c
            1384-1479           AL354928.9         160320-160415       c
            1480-1629           AL354928.9         159197-159346       c
            1630-1725           AL354928.9         158417-158512       c
            1726-1815           AL354928.9         150257-150346       c
            1816-1918           AL354928.9         149302-149404       c
            1919-2079           AL354928.9         149011-149171       c
            2080-2223           AL354928.9         148121-148264       c
            2224-2283           AL354928.9         142378-142437       c
            2284-2454           AL354928.9         141652-141822       c
            2455-2541           AL354928.9         141039-141125       c
            2542-4877           AL354928.9         138143-140478       c
FEATURES             Location/Qualifiers
     source          1..4877
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q33.3"
     gene            1..4877
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="golgin A1"
                     /db_xref="GeneID:2800"
                     /db_xref="HGNC:HGNC:4424"
                     /db_xref="MIM:602502"
     exon            1..113
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            114..163
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            164..453
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..2622
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="golgi autoantigen, golgin subfamily a, 1; gap
                     junction protein, alpha 4, 37kD"
                     /codon_start=1
                     /product="golgin subfamily A member 1"
                     /protein_id="NP_002068.2"
                     /db_xref="CCDS:CCDS6860.1"
                     /db_xref="GeneID:2800"
                     /db_xref="HGNC:HGNC:4424"
                     /db_xref="MIM:602502"
                     /translation="MFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDD
                     FASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSS
                     MRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQS
                     MNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMN
                     SNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLS
                     IDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHLQELLKEKTLAEQNLEDT
                     RQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQ
                     ESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQTTAEQGMRQLEQENAALKEC
                     RNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIID
                     EKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQ
                     EDLLRLRGPLQAEALSVNESHVTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQ
                     DLEQQLLEKNKTIKQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMAPSVT
                     NNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEY
                     KMSWFGSKPAPKGSIRPSISNPRIPWS"
     exon            454..544
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            545..619
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            620..717
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            718..750
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            751..879
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1049
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1161
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1287
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1383
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1479
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1480..1629
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1725
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..1815
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1816..1918
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2079
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            2080..2223
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            2224..2283
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2454
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            2455..2541
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..4877
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3925..3930
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="hexamer: AATAAA"
     polyA_site      3945
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="major polyA site"
     regulatory      4760..4765
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="hexamer: ATTAAA"
     polyA_site      4803
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="major polyA site"
     regulatory      4832..4837
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
                     /note="hexamer: ATTAAA"
     polyA_site      4877
                     /gene="GOLGA1"
                     /gene_synonym="golgin-97"
ORIGIN      
        1 ggttccgggt cgctgctcgg ctcgccggct gggcggtggg ggttggtgac gcgggccggg
       61 gctcacgaga ggcccgggag gcggggcttt gctggcttcc cagagagagg caggacagaa
      121 tgctttgacc tccaagctgt tttaaatcta gtagataagc cagatcctgt gttgccataa
      181 gcccttggcc cacatttaag tgggaatgca gctagcttgg atgtctgaaa ctttgtaggc
      241 gcctctgtct gaatcctgaa cacaggcacc aggactactg agagctcgtc atctgtgcag
      301 gatagccaca cagcaaacat gtttgcaaaa ctgaagaaga aaattgcaga agagactgct
      361 gttgctcaga ggccaggagg tgctactagg atcccacggt ctgtgagcaa ggaatcagtt
      421 gcctcaatgg gagctgactc aggagatgac tttgcttccg atggaagcag ctccagagaa
      481 gatctttcat cccagcttct gagaaggaat gaacagatac ggaagttaga ggccagactt
      541 tctgactatg ctgaacaggt ccgaaacttg cagaagataa aagagaagct tgaaattgca
      601 ttagaaaaac accaggattc ttccatgcgg aaatttcaag agcagaatga gacattccaa
      661 gccaacagag ccaaaatggc agaaggactg gctttggcat tagccagaaa ggaccaggaa
      721 tggtcagaaa agatggatca gcttgaaaag gagaaaaata ttctgacagc ccagttacag
      781 gaaatgaaga accagagtat gaatcttttc caaaggagag atgaaatgga tgaattagag
      841 gggttccagc agcaggaact aagtaaaata aagcacatgc ttttaaaaaa agaagaaagt
      901 ctagggaaaa tggaacaaga attggaggca cgaaccagag aacttagtcg tacccaggag
      961 gagttgatga actccaatca gatgtcatca gacttaagcc agaagctaga agaattgcag
     1021 agacactact caacgctgga agagcagaga gatcatgtga tagcttcaaa aacaggtgca
     1081 gaaagtaaga tcacagccct ggaacaaaag gaacaagagc tccaagcact cattcagcag
     1141 ctttccattg atttgcaaaa ggtcactgct gaaactcaag agaaagaaga cgttatcaca
     1201 catttgcaag agaaggttgc atccttggag aagagactag aacagaactt atcaggagaa
     1261 gaacacttgc aagaactcct gaaagagaaa acacttgctg agcagaattt ggaggatacc
     1321 agacaacagc tcttggcagc cagaagcagc caggctaagg ccattaacac cctggagact
     1381 cgggtgagag aactggagca gaccttgcag gcctctgagg agcagctcca acagagcaag
     1441 ggcattgtgg ctgcccagga aactcagata caggagctcg ctgccgccaa ccaggagagc
     1501 agccatgtgc agcagcaggc ccttgctctg gagcagcagt tcttggagcg cacccaggcg
     1561 ctagaagccc agatagtggc cctggagaga acgcgggcag ctgaccagac caccgcagag
     1621 caagggatga gacaactgga gcaagaaaat gcagccctta aagaatgcag gaatgaatat
     1681 gaacgttctt tacaaaatca ccaatttgaa ctaaagaagc tgaaggaaga atggagccaa
     1741 agagaaattg tgagcgtggc catggctcaa gccctggagg aggtgcggaa gcaaagggaa
     1801 gagttccagc aacaggcagc taacctgaca gccataatag acgagaagga acagaatctg
     1861 cgggaaaaaa ccgaagtgct tctccagaaa gagcaggaga ttctccagct ggagcgaggt
     1921 cacaactctg ccctgctgca gatacaccag ctgcaggccg agctggaggc cctgaggacc
     1981 ctcaaggcgg aggaggctgc agtggtcgcg gagcaggagg acctgctgag gctgcggggc
     2041 ccattgcagg ccgaagcact ctcagtcaat gagtcgcacg tgacctcgag ggccatgcag
     2101 gaccctgtgt tccagcttcc aactgcagga agaacaccaa atggtgaggt tggggccatg
     2161 gatctcacac agctacagaa ggagaaacag gacttggagc agcaacttct ggagaaaaat
     2221 aagaccataa agcagatgca gcagcggatg ctggagctcc ggaagactct gcagaaggag
     2281 ctgaaaatca gacccgataa tgagctcttc gaagtccggg agaaacctgg acctgagatg
     2341 gcaaacatgg cgccttccgt cacgaataac actgacctga cagatgcccg cgagatcaac
     2401 tttgagtacc ttaaacatgt ggttttaaaa ttcatgtctt gtcgcgaatc cgaggctttt
     2461 catcttataa aagctgtgtc agtgttgctg aacttttccc aagaggagga gaacatgctc
     2521 aaggaaactc tggaatataa gatgtcatgg tttgggtcca aaccagctcc caagggcagc
     2581 atccggccgt ctatctcaaa ccctcggata ccatggtcct agaggggact acccaaggat
     2641 ggagctccgt gggttgacac tttttctgtg aaaagaacac tgacacacca gtctgggtgg
     2701 gtttttaatc actgtaactg cagtattttg tacaagtgtc taaacattgt ttacaagact
     2761 aaggcccact tccctgcagg ctgacctgaa cctcaggggg tagctgatcc tgtcattctg
     2821 gtcaccaaac aggagggtcc tggcactacc cagatttcca cagtgctgct aatatcccag
     2881 ctccagccag caccccatct gcacctgaat cctctaactt cacggtagca cttacagctg
     2941 aagccatcag catctggcag gcacacctga gtcaccatgt agcgctgcta ctggaggtag
     3001 agacggccct ttgagatggt gcccagcagg ccaaacccac ctgcctctgc caggaacagc
     3061 caactccatg ggaactctat gggagtggct tttaaaaatt cagatgagtt agaagctttt
     3121 tatcccttcc tctcaagaaa atattctttc accctgtctc tcaaaccacc tagaacttta
     3181 gaggatccat ctttaagggt cggtgtggat gaatgagaaa atgcaccttt ctgacagtat
     3241 ctccacttta cttaagaaaa ctagcaaata tatgaaaaga cccttagtac caaatacact
     3301 caattgcctt tttaatgaat gtacttgtct tggataggtt gctggtaaac cattttaaac
     3361 tattttttat agctgaagtt cttcactact ataaacatgt cttctgtact ataaaatcca
     3421 tttaactggt gttcttaaaa tcagagcgtc cagaggaaat tcttcctaaa actaggattc
     3481 ctgttccttt gtcttctcac tcgcactctg gcactgctcc ctctgaagtg cagtgggatc
     3541 tcgtgtgctt tgtcttgatt ctgtgctgcg ctgccgctgg gcgatgcaga ccacctgtct
     3601 tctactgaag gacagtccgc tgtctccagt gggggcagca gctgtccccc agcctcgatg
     3661 gagacactgg ggcagtctgc cttgtctgtg gagctgctct ctctccctca tcccacccca
     3721 aatacttaaa atgacactac acccagacgg cgcccagctg gctgcagcac ttgtagcatg
     3781 cacatgactc tggtagtaac caacaaaaac ttgttttatg gattcctcgt ttactgagga
     3841 aagggaacat gctggttctg gaaaagccac aatattgaat ctaaaaggaa accgtttatt
     3901 gtttgatgaa agtttcactg gttaaataaa aaactaaatt aataactgga gcctctaaat
     3961 ttattatcca ttatccagtg atggaaagtt gtatttctca atcatgctta gggccaaaat
     4021 aggtatataa aatgtgtcac agaaaaacac gcatttgcaa cgttaaccta acgaaatttc
     4081 catgaagaac caagtcaggg cagcatctcc ttagtcccag ctcaggctct ctgccttcca
     4141 gaggccgctt ctccagtgac taacctcctc ctctggctcc tccttgcaga cagttatccc
     4201 ttgtttagaa cacgaatttc catttacctg gtgggaacac gaaacaggag tctcttctgt
     4261 tctgcaagtt tgatgggtaa gaggtagcct tttttcaaag taggatttcc tttttcaact
     4321 gttccaggaa agaatctcta agactgggta gctcacagcc agccaaaggc agctacattt
     4381 ccacagaagc ccatccgctg cctccgtggc ttctccagcc attgaactgg tcccacacgc
     4441 accccaggcc ccactcctcg gcagtttcag gtgtagctgt ggggcccgtt cctaggtctg
     4501 tactcacttt agggaggctt cactgactag gctttcctcc tgcatgttga atttccttca
     4561 gctttaagag gaagagtgga ataaatattc taagtgattt aatgcacttt gacttgtata
     4621 aaactttctg tgttagcgac ggtatctata gccctttata cgagcgatgg atcttgagct
     4681 ctccttccat gttgtaaata gggattgtat tcttgaaaac tgctgtagca aattcatctg
     4741 tggtgcaata cactttttga ttaaagctct tcaatccaga tgcaactaca atggatttta
     4801 ctagtttggt gtgtcagtat ttctttgact cattaaatct ggtattttgt gtctcatatt
     4861 taacactcca aggccaa
//
