LOCUS       NM_001396022             520 bp    mRNA    linear   PRI 08-APR-2024
DEFINITION  Homo sapiens G protein subunit gamma 5B (GNG5B), mRNA.
ACCESSION   NM_001396022
VERSION     NM_001396022.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
REFERENCE   2  (bases 1 to 520)
  AUTHORS   Hurowitz,E.H., Melnyk,J.M., Chen,Y.J., Kouros-Mehr,H., Simon,M.I.
            and Shizuya,H.
  TITLE     Genomic characterization of the human heterotrimeric G protein
            alpha, beta, and gamma subunit genes
  JOURNAL   DNA Res 7 (2), 111-120 (2000)
   PUBMED   10819326
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL031319.5.
            
            ##Evidence-Data-START##
            Transcript is intronless :: H16050.1, H42807.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000697560.1/ ENSP00000513336.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-520               AL031319.5         65722-66241         c
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq23"
     gene            1..520
                     /gene="GNG5B"
                     /gene_synonym="dJ364I1.1; GNG5P2; GNG5ps; HG3L1; HG3L3"
                     /note="G protein subunit gamma 5B"
                     /db_xref="GeneID:347687"
                     /db_xref="HGNC:HGNC:24826"
     exon            1..520
                     /gene="GNG5B"
                     /gene_synonym="dJ364I1.1; GNG5P2; GNG5ps; HG3L1; HG3L3"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..271
                     /gene="GNG5B"
                     /gene_synonym="dJ364I1.1; GNG5P2; GNG5ps; HG3L1; HG3L3"
                     /note="G protein gamma 5-like subunit; G protein subunit
                     gamma 5 pseudogene 2; dJ364I1.1 (G Protein (Guanine
                     Nucleotide-binding protein) Gamma 5 subunit (GNGT5, GNG5)
                     LIKE protein); guanine nucleotide binding protein (G
                     protein), gamma 5 pseudogene 2; heterotrimeric guanine
                     nucleotide-binding protein 3L1; heterotrimeric guanine
                     nucleotide-binding protein 3L3"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein
                     G(I)/G(S)/G(O) subunit gamma-5B"
                     /protein_id="NP_001382951.1"
                     /db_xref="CCDS:CCDS94650.1"
                     /db_xref="GeneID:347687"
                     /db_xref="HGNC:HGNC:24826"
                     /translation="MSGFSSVAATKKVVQQLQLEAGLNSVKVSQAAADLKQFCLQNAQ
                     HDPLLTGVSSSTNPFRPQKVCSFL"
     regulatory      490..495
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GNG5B"
                     /gene_synonym="dJ364I1.1; GNG5P2; GNG5ps; HG3L1; HG3L3"
                     /note="hexamer: AATAAA"
     polyA_site      520
                     /gene="GNG5B"
                     /gene_synonym="dJ364I1.1; GNG5P2; GNG5ps; HG3L1; HG3L3"
                     /note="major polyA site"
ORIGIN      
        1 ggccccgccg acccacggcc cacgacccac cgacccacga atcggcccgg cccccgcgtt
       61 caccatgtct ggcttctcca gcgtcgccgc tacgaagaaa gtggttcaac agctccagct
      121 ggaggccggg ctcaacagcg taaaagtttc ccaggcagct gcagacttga aacaattctg
      181 tctgcagaat gctcaacatg accctctgct gactggagta tcttcaagta caaatccctt
      241 cagaccccag aaagtctgtt cctttttgta gtacaatgaa tctttcaaag gtttcccaaa
      301 ccacttctta tgatccagtg aatattcaag agagatacat ttgaagcctg tacaaaagct
      361 tatccctgta acacatgtgc tgtaatatac aaaattctac ttttgtctgt ccttaacatc
      421 tacctctgaa tttttatgaa tttctacttc acaagggtaa ttgttttata tacattggca
      481 gcagcataca ataaaactta gtgtgcaagt tttaaaaaat
//
