LOCUS       XM_006713721            6428 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens G protein subunit beta 4 (GNB4), transcript
            variant X4, mRNA.
ACCESSION   XM_006713721
VERSION     XM_006713721.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000003.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_006713721.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6428
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
     gene            1..6428
                     /gene="GNB4"
                     /gene_synonym="CMTD1F; HG2B"
                     /note="G protein subunit beta 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 4
                     mRNAs, 21 ESTs, 624 long SRA reads, 23 Proteins, and 91%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 19 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:59345"
                     /db_xref="HGNC:HGNC:20731"
                     /db_xref="MIM:610863"
     CDS             281..1303
                     /gene="GNB4"
                     /gene_synonym="CMTD1F; HG2B"
                     /codon_start=1
                     /product="guanine nucleotide-binding protein subunit
                     beta-4 isoform X1"
                     /protein_id="XP_006713784.1"
                     /db_xref="GeneID:59345"
                     /db_xref="HGNC:HGNC:20731"
                     /db_xref="MIM:610863"
                     /translation="MSELEQLRQEAEQLRNQIQDARKACNDATLVQITSNMDSVGRIQ
                     MRTRRTLRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMT
                     CAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTS
                     SGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMC
                     RQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSV
                     AFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDS
                     FLRIWN"
ORIGIN      
        1 gggtctcccc gggctcgggc ggccgacgct gcccgggagg gacgaggagg gcgcgcctgt
       61 gtcgcgccca gctgccacgc gggaactggc cccacgaccg ccggcgcagg cacttcccgg
      121 gcggtccaga ccgctcgccc cggggagcga ggaacggtcg gcggtccaag tcctgcagac
      181 ccccctggtt tctcgtcact ccccgaggcc tccttccagg aactcagagc acgagcccct
      241 gttttcactc attagctcct gaggtaaaca aattgaaaaa atgagcgaac tggaacagtt
      301 gaggcaagaa gcagaacaac tgcggaatca gattcaggat gctcggaaag catgtaatga
      361 tgcaacgctt gttcagatta catcaaatat ggactctgtg ggtcgaatac aaatgcgaac
      421 aagacgtaca ctgaggggcc acctagctaa aatctatgct atgcattggg gatacgattc
      481 caggctgcta gtcagtgctt ctcaagatgg aaaattaatt atttgggata gctatacaac
      541 aaataagatg catgctattc ctttgaggtc ctcctgggtg atgacctgtg cttatgctcc
      601 ctctggtaat tatgttgcct gtggaggctt ggacaacatc tgctctatat ataacttaaa
      661 gaccagagag ggaaatgtga gagtaagccg agagttgcca ggtcacacag ggtacttgtc
      721 ctgctgtcgt tttttagatg acagccaaat tgttacaagt tcaggagata caacttgtgc
      781 tttatgggac atcgaaactg cccagcagac caccacattc actgggcatt ctggagatgt
      841 gatgagtctt tctttgagtc ctgacatgag gacttttgtt tctggtgctt gtgatgcctc
      901 ttccaaatta tgggatattc gagatggaat gtgtagacag tctttcacgg gacatgtctc
      961 agatatcaat gctgtcagtt ttttcccaaa tggatatgcc ttcgccactg gctctgatga
     1021 tgccacttgc cggctctttg accttcgtgc agatcaagag ttattattgt attctcatga
     1081 caatatcatc tgtggaatca cttctgtagc cttctcaaaa agtgggcgtc tcttgttggc
     1141 tggttacgat gactttaatt gtaatgtatg ggacacgcta aaaggagatc gtgcaggtgt
     1201 ccttgctggt catgacaacc gtgtgagctg cttaggtgta actgatgatg gcatggctgt
     1261 ggcaacaggc tcttgggaca gttttcttag aatctggaat taacagtgtc atacatattt
     1321 gttctccatt gatatatctg gagaaatcaa tgctacagcc tatagctgtg aaaaaattct
     1381 accttatatt tgcaggtgaa gatttttcta ttagattatc tacaaaaaca agctttcagt
     1441 aaactaccaa aaaaaaagtg ggggtggagg aaaaaaggca aaggcgcctt ctgagatcaa
     1501 aaggaccagt gtattaattt gaggggttgg gttattttaa ccttggtgaa ttgttgtgtg
     1561 tactcagagt gtattttctt tgtgtagaac agaatgtaca cattatagca gctcgccatt
     1621 gtgtttgcat tttttaagaa gtacattttt aactttgtat acacaagaaa tgtcatattt
     1681 ttgagttttg taatggaaga accaggcaca gaaacagaca gaaatgatac tgtatgtgtg
     1741 tgtatttatg tctgaagaaa gtccccttga attctgatat ctctttgaat ctaagagatc
     1801 ctgatagctt catgtttaag agcattgaca ggtggggcac ctctgagggg agttcattgt
     1861 ttctcatgca tcatttgcca tatactatta atcaaagtgc ttgctttcag tcctttgagg
     1921 ggacagataa tctgaaggcc agagattaga gatttcactg atattttgga catacataag
     1981 aaacatcatt ataattaata aaaagtaggt aatagcatat aaatggttct tgacatttta
     2041 aaagcctggt tatgatcagt tgacactttg agtacccccc taaatagctg gactttcctt
     2101 ttcatttcat atttggaact aagtttgtag cgtatactca tctttcagaa gtttggtaaa
     2161 cattgggatt gtccctgcat ctgaacatct ttcccagtgc tatcagtata catctagaga
     2221 ggaaatgcaa tgtgacagtg ttacatttgg agagaagtgt gaaatctaac caatcgctag
     2281 cacatatttg ttgtaatacg gtggtttatt tcatgtttgc atactataaa atctgaattg
     2341 atgtgaaata tctgtgcctt taaatttctt aaacctttaa gctttttgtt ctgttttgca
     2401 acattttgta gtatttcttc ccttccttag cacaaaatac tggtttctaa gtggttttgc
     2461 ttcaaaggat gtctagatgt aagtgattcc acttaaagcc aaaataaaaa ttcctaaagc
     2521 agttcttaaa ggagttagag agctatatta aacagttttt ctgtggtata ataatgtgtc
     2581 tcttactaga agtcccccac gaccaagtta aagatacttt tcctgttgga ttctctttta
     2641 caaataagtc taaatgactg ataatagaag attgttagtc ttgcttgatg gtaaagtctt
     2701 ggattattct gatatataga cgtgcattgt tttgtaactt agttactttt cagataggtc
     2761 tgtgttaact tttgaacatg tgtaacttaa cctaaatact cccaaacttt acctctaaat
     2821 ttttgttttt atgttgtgaa tgtgctaata tgtgcatcaa ctgtaaagat gtatcagttt
     2881 tattaaaatc agttgacaat tagaataata aagtggataa aggcaaatta agatatagga
     2941 ccaaaacaga atattgtaga tggcagttat gaatgtatat ttatattttg attaagattt
     3001 ctattaactt tttggctggg cagagtggct tacacctata atcccagcaa tttgggaggc
     3061 caaggtgggc agatcacttg aggtcaggag ttcgcgacca gcctacccaa catggtgaaa
     3121 ccccatctct tctaaaaata caaacattag ccgggcgtgg tggcacattc ctgtaatccc
     3181 agctactcgg gaggctgagg caggagattc gcctgaaccc gggaggcaga ggttgcagtg
     3241 agccgagatt gtgccactgc actccagcct aggcgacaga gtgagactcc atctcaaatt
     3301 ggaaaaaaaa aaaattatat gaacttttgc tattaatgtt tatttgtagg ctatttatat
     3361 cacttcataa agaacagttc tttgagaaaa gaataaagga atgtattcat ttccagaaaa
     3421 agagggttgg ggaaagtttg ccatgtaggt tagtcagaag aaagcaattc tattatgcat
     3481 aaaaataacc ttaaatatgt aagagagtat ctcctctact taaaagttat tatagtagtc
     3541 acaggcatac agaccacagg aattctatgg tcttaacata ttttaaaatt acatttattt
     3601 taatgttctt aaagtttatg aagaggagtt taaagcaatt cccataatta aatatttact
     3661 cggcaactaa aaactattta acacttgtgg ttaattatac acataaacaa atggcgacag
     3721 agtagcctca ctaccacaat tacttcatgg ttacaccttt gctttctaat aataggggct
     3781 ccagttgcta aatatatttg tttacttaca gtttaagttg agctgattgt tgaattctgt
     3841 tattgttcct gaattcaatg agtatataat ttgtagagat gttgaatagt ttggatctta
     3901 gtttttaagg ctgaaaaatc tggctggatt tagtttttaa aaatttgcat catcaagaat
     3961 attgcagtta atgttccttt tttttttttt ttaaagacag agtctcactc tgtcacccag
     4021 gctggagtgt acagtggtgt gattttggct cattgcaacc tcaacctctg cctcctgggt
     4081 tcaagcaatt cttgtgcctc agcctcccaa gtagctggga ctataggcat gtgccaccat
     4141 gcccggctaa tttttgtatt tttagtagag atggggtttc accatcttgg ccagtctgat
     4201 ctcgtactcc tggcctcaag tgatccacca gcctcagcct cccaaagtgc tgggattaca
     4261 gacgtgagcc accgtgccca gccaggtttc cttctttacc ttctaagaaa catttaaaca
     4321 taatgtgcct gagaaggtta atttgttgac tctgtagcat gtcaagaaga gtagtttttt
     4381 gagatctggc aagaatattt tagagataca tattcttttc taagtatgtt atcaccctgt
     4441 ggtgttgagc atatcgtccc aaaaacctgc ttcagcaagc agttcttggc caggcatggt
     4501 ggctcacacc tgtaatccca gcactttggg aggccgaggc aggtggatca cgaggtcagg
     4561 agttcaagac cagcctggcc aagatggtga aaccccatct ctactaaaaa tacaaaaatt
     4621 agccgggcgt ggaggtgggc gcctgtcagc tactcgtgag gctgaggcag agaattactt
     4681 gaactcagga ggtggaggtt ttggtgagct gagatggcgc cactgcactc caacccgagc
     4741 gacagagcaa gattccgtcc caaaaagaaa aagcagtttt tgccatcagc aaggatatct
     4801 cctccacttt aatggacagg cctcattttt ggcagctatg ctgtttgaga tgtagactga
     4861 atatccaagg ttcctcccta gctcaagttt ttacttgtga ttacacacac cacattgaat
     4921 tccgtcttca gaggcaaaga tttgggcttc atatctcaac agcaaaaggg cctgttcagc
     4981 aattcccttc attttagact catatgacct cagcgattgc atgatagtag taaactagtc
     5041 tcctggaaat aatggatgta ggtgcttcta gaatatgtta cagaatttca gacttaacct
     5101 attaatagat aaatggatct tgacttaagg tgacaaaatg aaacttttat tattgcttaa
     5161 aaatgctgtg ccaatattgt ataactagct cctctaatac ttttggtatt ttggatttaa
     5221 taataagacc ttaagcattt taaatgtgaa catgttcagg gaagtatgct ttgatgtaaa
     5281 tgtctcagat ctaagttgta acacaattga atacttgtgg cttattcttg gtttaactta
     5341 ggaaaactgg ttaaacaatc ccccatttgg gcctgtcatc attttaatag tgacgatgtt
     5401 ctttctgaaa tcttcagggt cggagtcagg ctgaattttt ttaaaaatta aatattatgt
     5461 tcaaattctt tcctttttgc cattgtgaaa aagcaaaatt ttaaatgatt tctcctgtta
     5521 gaatttttaa aaatacccac aggttggacc atctttctta tgggttgcac aatgaattta
     5581 tattttaaat tagattaagt agaatgtgaa gtacatttca gatttactag ttttctttcc
     5641 attgttcatt ttgggttgcc tcagattcag tgtatatttt aaaatattgg ttacataata
     5701 ggtactcaat gaaatggttt atagtagaat atctaagcta gcactttatt ttaaaaagta
     5761 acttattaat taatcacaca ttgatggtac accttgtatt tagcaaatgt ttgcatgttg
     5821 ataaaatctc ctatgtcttc tttcttaaat ccagttgctg attttgtaaa atacagttgt
     5881 gataaagcag cattacgggg gggaaaaagc tatattccaa ctggtgttaa atgtattcaa
     5941 caaaatctta catcatacag tatttatttc ttaattaata gaacttcagt gatatacttg
     6001 gtagatatct caagcctttt gtcttttaca caatggtgct ctatcctatt gttttctttt
     6061 caaagaagca tctgaacact tgcatttcta ttttcctatc caaaggcatc cacatctaag
     6121 tgtgttttta aagttgatta aaattatttt tctgttaaag cattctgaaa gtgtttgtct
     6181 ttacctagaa tgatttgtac acactcgtgg tcaactgaac atgaatgtca gtagtagtct
     6241 aattatggga agggtaaacg tgttagatta aggctcttaa agctctaaac catataaact
     6301 atggacttgt atcatgattt aactgttctt agatctttct tacacagtga ttcattcctc
     6361 tatttgtaca gtggctttat gaaatgttgt gaattgatac tgtaatcaat aaagtgcttt
     6421 taaccaga
//
