LOCUS       NM_001389717            1886 bp    mRNA    linear   PRI 16-FEB-2024
DEFINITION  Homo sapiens glycine-N-acyltransferase like 1 (GLYATL1), transcript
            variant 12, mRNA.
ACCESSION   NM_001389717
VERSION     NM_001389717.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1886)
  AUTHORS   Eich,M.L., Chandrashekar,D.S., Rodriguez Pen,A. MDC, Robinson,A.D.,
            Siddiqui,J., Daignault-Newton,S., Chakravarthi,B.V.S.K.,
            Kunju,L.P., Netto,G.J. and Varambally,S.
  TITLE     Characterization of glycine-N-acyltransferase like 1 (GLYATL1) in
            prostate cancer
  JOURNAL   Prostate 79 (14), 1629-1639 (2019)
   PUBMED   31376196
  REMARK    GeneRIF: study characterizes the expression of
            glycine-N-acyltransferase like 1(GLYATL1) in prostate cancer and
            explores its regulation in prostate cancer
REFERENCE   2  (bases 1 to 1886)
  AUTHORS   Matsuo,M., Terai,K., Kameda,N., Matsumoto,A., Kurokawa,Y.,
            Funase,Y., Nishikawa,K., Sugaya,N., Hiruta,N. and Kishimoto,T.
  TITLE     Designation of enzyme activity of glycine-N-acyltransferase family
            genes and depression of glycine-N-acyltransferase in human
            hepatocellular carcinoma
  JOURNAL   Biochem Biophys Res Commun 420 (4), 901-906 (2012)
   PUBMED   22475485
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001652.4, AP001636.4 and KF459756.1.
            
            On Feb 8, 2021 this sequence version replaced NM_001389717.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: BG427782.1, SRR5189664.90214.1
                                    [ECO:0000331]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                AP001652.4         138248-138319
            73-387              AP001652.4         139468-139782
            388-432             AP001636.4         9922-9966
            433-556             AP001636.4         10925-11048
            557-676             AP001636.4         14428-14547
            677-784             AP001636.4         15240-15347
            785-911             AP001636.4         22152-22278
            912-1089            AP001636.4         22558-22735
            1090-1794           AP001636.4         22992-23696
            1795-1886           KF459756.1         1-92
FEATURES             Location/Qualifiers
     source          1..1886
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..1886
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="glycine-N-acyltransferase like 1"
                     /db_xref="GeneID:92292"
                     /db_xref="HGNC:HGNC:30519"
                     /db_xref="MIM:614761"
     exon            1..72
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            73..387
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            388..432
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            433..556
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            557..676
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             599..1507
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /EC_number="2.3.1.68"
                     /note="isoform 2 is encoded by transcript variant 12;
                     glycine N-acyltransferase-like protein 1; acyl-CoA:glycine
                     N-acyltransferase-like protein 1; glutamine
                     N-acyltransferase"
                     /codon_start=1
                     /product="glycine N-acyltransferase-like protein 1 isoform
                     2"
                     /protein_id="NP_001376646.1"
                     /db_xref="CCDS:CCDS55768.1"
                     /db_xref="GeneID:92292"
                     /db_xref="HGNC:HGNC:30519"
                     /db_xref="MIM:614761"
                     /translation="MILLNNSHKLLALYKSLARSIPESLKVYGSVYHINHGNPFNMEV
                     LVDSWPEYQMVIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQ
                     IQGLQESLGEGIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSKLGSWAETGHPDD
                     EFESETPNFKYAQLDVSYSGLVNDNWKRGKNERSLHYIKRCIEDLPAACMLGPEGVPV
                     SWVTMDPSCEVGMAYSMEKYRRTGNMARVMVRYMKYLRQKNIPFYISVLEENEDSRRF
                     VGQFGFFEASCEWHQWTCYPQNLVPF"
     exon            677..784
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            785..911
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1089
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1886
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1864..1869
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="hexamer: AATAAA"
     polyA_site      1886
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="major polyA site"
ORIGIN      
        1 agacaggcaa gagagaagtc ttcccaacac ctgcgaatcg ggagcagcgg gcactagcac
       61 gtgcactgtc tggtcacccg ccaggtttgt ggcctgtgat ctcttgtcac cttggtctct
      121 cagctttgtc ttctgaaatc tggacttcca attgtctttg tcttgctgcc cttccttgcg
      181 acactggcct ggaatccctc acggtagtct gctggagtgg aatttaggac gcatctcagt
      241 tgtcaccatc tttaattgca tgatgtctag ttccttgcaa accattattt catgtatttc
      301 gctctttttt gtttgttttg ttttgttttg ttttcaggct aggggaaaat ccagtccctg
      361 ttactccatt ttggccagaa attcaaggtg aagaaatgga gttgccatca actaagttga
      421 gaaagactac agatggtgtc acaagaagga tctgaagtgg agcttctagt atccccagga
      481 gcgcgaagtg aacacggaag gtacctgcag gatccaattg tgtccattga tctctcagag
      541 tggctgagga taatagagtt tcttcttcaa ggtctcaagg tctgaagcat cccacagaat
      601 gatcctactg aataactccc ataagctgct ggccctatac aaatccttgg ccaggagcat
      661 ccctgagtcc ctgaaggtgt atggctctgt gtatcacatc aatcacggga accccttcaa
      721 catggaggtg ctggtggatt cctggcctga atatcagatg gttattatcc ggcctcaaaa
      781 gcaggagatg actgatgaca tggattcata cacaaacgta tatcgtatgt tctccaaaga
      841 gcctcaaaaa tcagaagaag ttttgaaaaa ttgtgagatc gtaaactgga aacagagact
      901 ccaaatccaa ggtcttcaag aaagtttagg tgaggggata agagtggcta cattttcaaa
      961 gtcagtgaaa gtagagcatt cgagagcact cctcttggtt acggaagata ttctgaagct
     1021 caatgcctcc agtaaaagca agcttggaag ctgggctgag acaggccacc cagatgatga
     1081 atttgaaagt gaaactccca actttaagta tgcccagctg gatgtctctt attctgggct
     1141 ggtaaatgac aactggaagc gagggaagaa tgagaggagc ctgcattaca tcaagcgctg
     1201 catagaagac ctgccagcag cctgtatgct cggcccagag ggagtcccgg tctcatgggt
     1261 aaccatggac ccttcttgtg aagtaggaat ggcctacagc atggaaaaat accgaaggac
     1321 aggcaacatg gcacgagtga tggtgcgata catgaaatat ctgcgtcaga agaatattcc
     1381 attttacatc tctgtgttgg aagaaaatga agactcccgc agatttgtgg ggcagtttgg
     1441 tttctttgag gcctcctgtg agtggcacca atggacttgc tacccacaga atctagttcc
     1501 attttagaca atgaagctgc ttagtaatct ctgccaagcc atctcttaat attaaagcag
     1561 acaccacaga atagatttct tcacttacaa atgcatattg ggcacttata atacagcagg
     1621 aactcttctc acctggagcc ttgatgttaa aagacacagc catgctcttg aggagcttac
     1681 aatcctggct ggaggcaggg gagggtatat tctttaaata tgcttaagtg ttatagggaa
     1741 agacggggtt accagtaaac atgtaactag aaagccaggc tcagttctta cctctgggaa
     1801 tcagaactct ttatgcaact tggttaatag aatctactat ctggaagata aatgaaggat
     1861 tttaataaaa ttttcaatag aataaa
//
