LOCUS       NM_001389712            1617 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens glycine-N-acyltransferase like 1 (GLYATL1), transcript
            variant 7, mRNA.
ACCESSION   NM_001389712
VERSION     NM_001389712.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1617)
  AUTHORS   Eich,M.L., Chandrashekar,D.S., Rodriguez Pen,A. MDC, Robinson,A.D.,
            Siddiqui,J., Daignault-Newton,S., Chakravarthi,B.V.S.K.,
            Kunju,L.P., Netto,G.J. and Varambally,S.
  TITLE     Characterization of glycine-N-acyltransferase like 1 (GLYATL1) in
            prostate cancer
  JOURNAL   Prostate 79 (14), 1629-1639 (2019)
   PUBMED   31376196
  REMARK    GeneRIF: study characterizes the expression of
            glycine-N-acyltransferase like 1(GLYATL1) in prostate cancer and
            explores its regulation in prostate cancer
REFERENCE   2  (bases 1 to 1617)
  AUTHORS   Matsuo,M., Terai,K., Kameda,N., Matsumoto,A., Kurokawa,Y.,
            Funase,Y., Nishikawa,K., Sugaya,N., Hiruta,N. and Kishimoto,T.
  TITLE     Designation of enzyme activity of glycine-N-acyltransferase family
            genes and depression of glycine-N-acyltransferase in human
            hepatocellular carcinoma
  JOURNAL   Biochem Biophys Res Commun 420 (4), 901-906 (2012)
   PUBMED   22475485
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AP001636.4 and KF459756.1.
            
            On Feb 8, 2021 this sequence version replaced NM_001389712.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189652.95174.1,
                                           SRR5189661.52863.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000532726.6/ ENSP00000436116.2
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-163               AP001636.4         6870-7032
            164-287             AP001636.4         10925-11048
            288-407             AP001636.4         14428-14547
            408-515             AP001636.4         15240-15347
            516-642             AP001636.4         22152-22278
            643-820             AP001636.4         22558-22735
            821-1525            AP001636.4         22992-23696
            1526-1617           KF459756.1         1-92
FEATURES             Location/Qualifiers
     source          1..1617
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /map="11q12.1"
     gene            1..1617
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="glycine-N-acyltransferase like 1"
                     /db_xref="GeneID:92292"
                     /db_xref="HGNC:HGNC:30519"
                     /db_xref="MIM:614761"
     exon            1..163
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            164..287
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            288..407
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     CDS             330..1238
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /EC_number="2.3.1.68"
                     /note="isoform 2 is encoded by transcript variant 7;
                     glycine N-acyltransferase-like protein 1; acyl-CoA:glycine
                     N-acyltransferase-like protein 1; glutamine
                     N-acyltransferase"
                     /codon_start=1
                     /product="glycine N-acyltransferase-like protein 1 isoform
                     2"
                     /protein_id="NP_001376641.1"
                     /db_xref="CCDS:CCDS55768.1"
                     /db_xref="GeneID:92292"
                     /db_xref="HGNC:HGNC:30519"
                     /db_xref="MIM:614761"
                     /translation="MILLNNSHKLLALYKSLARSIPESLKVYGSVYHINHGNPFNMEV
                     LVDSWPEYQMVIIRPQKQEMTDDMDSYTNVYRMFSKEPQKSEEVLKNCEIVNWKQRLQ
                     IQGLQESLGEGIRVATFSKSVKVEHSRALLLVTEDILKLNASSKSKLGSWAETGHPDD
                     EFESETPNFKYAQLDVSYSGLVNDNWKRGKNERSLHYIKRCIEDLPAACMLGPEGVPV
                     SWVTMDPSCEVGMAYSMEKYRRTGNMARVMVRYMKYLRQKNIPFYISVLEENEDSRRF
                     VGQFGFFEASCEWHQWTCYPQNLVPF"
     exon            408..515
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            516..642
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            643..820
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     exon            821..1617
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1595..1600
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="hexamer: AATAAA"
     polyA_site      1617
                     /gene="GLYATL1"
                     /gene_synonym="GATF-C; GNAT"
                     /note="major polyA site"
ORIGIN      
        1 cagttgccat gggccaggag tctcacagaa ctactaagca gctgcttacc caattttggc
       61 tggagagata agtaccctct ggggccacca cagctggccc caaccatggt cctgattgcc
      121 ttggaagaac tgcctttgga atttcacatc ggcatccaga tagatggtgt cacaagaagg
      181 atctgaagtg gagcttctag tatccccagg agcgcgaagt gaacacggaa ggtacctgca
      241 ggatccaatt gtgtccattg atctctcaga gtggctgagg ataatagagt ttcttcttca
      301 aggtctcaag gtctgaagca tcccacagaa tgatcctact gaataactcc cataagctgc
      361 tggccctata caaatccttg gccaggagca tccctgagtc cctgaaggtg tatggctctg
      421 tgtatcacat caatcacggg aaccccttca acatggaggt gctggtggat tcctggcctg
      481 aatatcagat ggttattatc cggcctcaaa agcaggagat gactgatgac atggattcat
      541 acacaaacgt atatcgtatg ttctccaaag agcctcaaaa atcagaagaa gttttgaaaa
      601 attgtgagat cgtaaactgg aaacagagac tccaaatcca aggtcttcaa gaaagtttag
      661 gtgaggggat aagagtggct acattttcaa agtcagtgaa agtagagcat tcgagagcac
      721 tcctcttggt tacggaagat attctgaagc tcaatgcctc cagtaaaagc aagcttggaa
      781 gctgggctga gacaggccac ccagatgatg aatttgaaag tgaaactccc aactttaagt
      841 atgcccagct ggatgtctct tattctgggc tggtaaatga caactggaag cgagggaaga
      901 atgagaggag cctgcattac atcaagcgct gcatagaaga cctgccagca gcctgtatgc
      961 tcggcccaga gggagtcccg gtctcatggg taaccatgga cccttcttgt gaagtaggaa
     1021 tggcctacag catggaaaaa taccgaagga caggcaacat ggcacgagtg atggtgcgat
     1081 acatgaaata tctgcgtcag aagaatattc cattttacat ctctgtgttg gaagaaaatg
     1141 aagactcccg cagatttgtg gggcagtttg gtttctttga ggcctcctgt gagtggcacc
     1201 aatggacttg ctacccacag aatctagttc cattttagac aatgaagctg cttagtaatc
     1261 tctgccaagc catctcttaa tattaaagca gacaccacag aatagatttc ttcacttaca
     1321 aatgcatatt gggcacttat aatacagcag gaactcttct cacctggagc cttgatgtta
     1381 aaagacacag ccatgctctt gaggagctta caatcctggc tggaggcagg ggagggtata
     1441 ttctttaaat atgcttaagt gttataggga aagacggggt taccagtaaa catgtaacta
     1501 gaaagccagg ctcagttctt acctctggga atcagaactc tttatgcaac ttggttaata
     1561 gaatctacta tctggaagat aaatgaagga ttttaataaa attttcaata gaataaa
//
